ライフサイエンスコーパス: perivascular cell

1 of microglia and has little or no effect on perivascular cells.

2 culture, are themselves derived in part from perivascular cells.

3 ed from both endothelial and Lepr-expressing perivascular cells.

4 including lumen formation and recruitment of perivascular cells.

5 rise to interstitial cardiac fibroblasts and perivascular cells.

6 ies implicating osteoblasts, endothelial and perivascular cells.

7 ently due to the insufficient recruitment of perivascular cells.

8 ires a ready source of endothelial cells and perivascular cells.

9 adjacent to lumens, confirming their role as perivascular cells.

10 activity of fresh, adult CNS parenchymal and perivascular cells.

11 In the absence of Arf, perivascular cells accumulate within the HVS and prevent

12 We show that a Nestin-Cre transgene targets perivascular cells (adventitial cells and pericyte-like

13 malian cardiomyocytes, is sharply induced in perivascular cells after injury to the adult zebrafish h

14 f the remaining vasculature by enhancing the perivascular cell and basement membrane coverage.

15 helium through co-seeding of endothelial and perivascular cells and a two-phase culture protocol.

16 rain barrier and was found in brain vessels, perivascular cells and in brain parenchyma 30 min after

17 of HO-1 immunoreactivity in CD163-expressing perivascular cells and infiltrating monocytes/macrophage

18 Ang1 is constitutively produced by perivascular cells and is protective of the adult vascul

19 f gp41 and iNOS was present predominantly in perivascular cells and most often in the basal ganglia.

20 ion site, meninges surrounding the brain and perivascular cells and neuron-like cells throughout the

21 ocyte survival or proliferation; a supply of perivascular cells and possibly other cell types such as

22 CTGF activated bone marrow-derived perivascular cells and promoted fibrovascular membrane f

23 nd differentiate tumor vessels from both the perivascular cells and the matrix.

24 eport a mechanism of the interaction between perivascular cells and tumour-associated macrophages (TA

25 fibroblasts in the three layers of meninges, perivascular cells, and ependymocytes and in a populatio

26 rupted co-localization of ECs with desmin(+) perivascular cells, and reduction of blood flow primaril

27 tional vessels, a reduced vessel coverage by perivascular cells, and were more necrotic.

28 ium and their cognate receptors expressed on perivascular cells are involved in blood vessel maturati

29 lete loss of mature osteoblastic cells while perivascular cells are maintained.

30 These results identify perivascular cells as fibro/adipogenic progenitors in WA

31 COX-2 was induced in endothelial cells, perivascular cells as well as infiltrating leukocytes 1

32 ested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs

33 Later, vascular and perivascular cells associated with smaller penetrating b

34 type I collagen and Dspp gene expression in perivascular cells associated with the pulp stones.

35 obust expression of COX2 mRNA was induced in perivascular cells between 45 min and 6 h after LPS inje

36 g bone remodeling originate from bone marrow perivascular cells, bone remodeling compartment canopy c

37 ult tcf21(+) cells revealed contributions to perivascular cells, but not cardiomyocytes, during each

38 Cathepsin K was localized to some perivascular cells by in situ hybridization.

39 Activation of PDGFRalpha signaling in perivascular cells causes them to transition into ECM-sy

40 adult organ at 3 mo of age, these NC-derived perivascular cells continue to be associated with the va

41 r to normal perivascular cells, hMSC-derived perivascular cells contracted in response to endothelin-

42 traparenchymal cells that networked with the perivascular cells coursing in the sheaths of adjacent b

43 cediranib treatment induced normalization of perivascular cell coverage and thinning of the basement

44 not change the functional vessel density and perivascular cell coverage in both tumor variants.

45 gration of mural cells in vitro and improved perivascular cell coverage in vivo.

46 c vascular network likely via regulating the perivascular cell coverage of the vessels thus affecting

47 impaired lymphatic vessel function, enhanced perivascular cell coverage, and abnormal lymphatic vesse

48 h infrequent vascular branches and increased perivascular cell coverage.

49 decreased alpha-smooth muscle actin-positive perivascular cell coverage.

50 lesions CCR1+/CCR5+ monocytes were found in perivascular cell cuffs and at the demyelinating edges o

51 Genetic inactivation of Klf4 in perivascular cells decreased formation of a pre-metastat

52 with human cells, including endothelial and perivascular cells derived from induced pluripotent stem

53 ols, whereas the frequency of CXCR4-positive perivascular cells did not correlate with disease severi

54 ular tissue engineering and for the study of perivascular cell differentiation.

55 The origin of these scars is thought to be perivascular cells entering lesions on ingrowing blood v

56 We conclude that perivascular cells exhibit the lower threshold to COX-2

57 Moreover, CD146(+) perivascular cells express, natively and in culture, mol

58 Perivascular cells expressing phosphorylated PDGFR-beta

59 atopoietic stem cells is present in CD146(+) perivascular cells extracted from the nonhematopoietic a

60 discussion, and current consensus holds that perivascular cells form mesenchymal stem cells in most t

61 Similar to normal perivascular cells, hMSC-derived perivascular cells cont

62 Perivascular cells, however, quickly resumed proliferati

63 To enhance the recruitment of perivascular cells, human umbilical vein endothelial cel

64 deletion from vascular endothelial, but not perivascular, cells impeded tumor growth, suggesting a v

65 Zyme is immunolocalized to perivascular cells in monkey cortex and the AD brain.

66 uted throughout the BM, and on pericytes and perivascular cells in multiple organs.

67 revealed a previously unidentified role for perivascular cells in pre-metastatic niche formation and

68 expressed at enhanced levels in vascular and perivascular cells in scleroderma skin samples.

69 The role of prostaglandins produced by these perivascular cells in the cerebral components of the acu

70 ad activation of macrophages, microglia, and perivascular cells in the CNS are held in check.

71 ss is known about the origin and turnover of perivascular cells in the human central nervous system.

72 Cell, Kramann et al. (2016) show that Gli1+ perivascular cells in the outermost vessel layer are pro

73 lineage-tracing models to trace the fate of perivascular cells in the pre-metastatic and metastatic

74 ass II (OX3) molecules was detected in a few perivascular cells in the retina of chimeric rats treate

75 utative glial cells in the soma clusters and perivascular cells in the walls of arterioles.

76 we use a developmental model to investigate perivascular cells in white adipose tissue (WAT) and the

77 Perivascular cells, including vascular smooth muscle cel

78 leaky blood vessels, disrupted endothelium - perivascular cell interactions, endothelial cell vacuoli

79 creased the recruitment and incorporation of perivascular cells into tumor blood vessels and increase

80 Pericytes, perivascular cells involved in microvascular function, e

81 Presumptive perivascular cells lining large blood vessels had extrem

82 Pericytes are perivascular cells localized to capillaries that promote

83 We show that perivascular cells lose the expression of traditional vS

84 In the HVS, Arf expression in perivascular cells may block their accumulation or repre

85 pericytes (also defined as mural, Rouget, or perivascular cells) may play during angiogenesis, vascul

86 Our analysis also reveals that perivascular cells migrate into the gonad from the meson

87 ues and protein delivery into nonendothelium perivascular cells, neurons, and astrocytes within 2 d o

88 mice, CTGF was prominently expressed in the perivascular cells of arteries.

89 ctivity and synthesis of prostaglandin E2 by perivascular cells of the cerebral vasculature.

90 emaphorin receptor Nrp-1 is expressed on the perivascular cells of the collecting lymphatic vessels.

91 pothalamus, cyclooxygenase-2 fluorescence in perivascular cells of the paraventricular nucleus of hyp

92 Importantly, PDGFRs were expressed only in perivascular cells of this tumor type, suggesting that P

93 ent is the reduction of both endothelial and perivascular cell populations.

94 In conclusion, hMSCs are perivascular cell precursors and may serve as an attract

95 y gene Klf4 in these phenotypically switched perivascular cells promoted a less differentiated state,

96 of coronary veins, while HH signaling to the perivascular cell (PVC) is necessary for coronary arteri

97 A small population of cells with perivascular cell (PVC)-like properties was found.

98 GE(2)) synthesis by endothelial (ECs) and/or perivascular cells (PVCs) (a macrophage-derived vascular

99 r cell types, endothelial cells (ECs) versus perivascular cells (PVCs; a subset of brain-resident mac

100 This study was conducted to determine the perivascular cell responses to increased endothelial cel

101 naling in cardiac myocytes, as compared with perivascular cells, resulting in excessive coronary arte

102 ndothelia and differential interactions with perivascular cells seeded in the collagen bulk; and we d

103 dent signals and prevent the accumulation of perivascular cells selectively in a vascular bed destine

104 In adult mouse bone marrow, perivascular cells shape a "niche" for HSPCs.

105 of perivascular cells, we hypothesized that perivascular cells similarly regulate tumor cell fate at

106 We used perivascular-cell-specific and pericyte-specific lineage

107 Perivascular cells such as macrophages and mast cells th

108 CD146(+) perivascular cells support the long-term persistence, th

109 dominantly present in stromal, vascular, and perivascular cells surrounding nests of tumor cells.

110 Transducing the Shh signal is a perivascular cell-the pericyte-rather than the more inte

111 we found that Scf was primarily expressed by perivascular cells throughout the bone marrow.

112 his study was to examine the contribution of perivascular cells to odontoblasts during the developmen

113 Sox10(+) stem cells could differentiate into perivascular cells to stabilize newly formed microvessel

114 ptoclast is a specialized, cathepsin B-rich, perivascular cell type that accompanies invading capilla

115 me cases, colocalization of HDMEC with mouse perivascular cells was observed.

116 Given the well-described plasticity of perivascular cells, we hypothesized that perivascular ce

117 smooth muscle cells (HSVSMCs) as a source of perivascular cells, were combined in Matrigel and implan

118 differentiation antigen, identifying them as perivascular cells, whereas none coexpressed endothelial

119 lood barrier also includes a large number of perivascular cells with both macrophage and melanocyte c

120 ent a unique subtype of microvessel-residing perivascular cells with diverse angiogenic functions and

121 in the kidney detected evident expression in perivascular cells, with negligible expression in the en

122 liposomes accumulated in a subpopulation of perivascular cells within the brain.

123 Arf was selectively expressed in perivascular cells within the vitreous of the postnatal

124 f cells (endothelial cells, ablumenal cells, perivascular cells) within the inner retina; however, th