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1 ibers without affecting absolute sensitivity permanently.
2 maculopathies that can reduce central vision permanently.
3 s in which the investigated molecule changes permanently.
4 eficits that affect humans and other mammals permanently.
5 tively repairing or replacing damaged joints permanently.
6 o halt or exit the cell cycle temporarily or permanently.
7 ogies that prevent content from being stored permanently.
8 thyroid function of neonates transiently or permanently.
9 ergoing intubation elected to keep the stent permanently; 34% (n = 22) had an eyelid-tightening proce
12 shape change, the CAN structure responds by permanently adjusting its structure through either rever
15 t developmental chronic circadian disruption permanently affects somatic and behavioral development i
16 n, and that a history of stress exposure can permanently alter gene expression patterns in the hippoc
17 rgeted biochemical modifications that do not permanently alter the DNA sequence (epigenome editing) m
18 anthropogenic inputs to natural systems may permanently alter the natural signatures of REE, motivat
22 terrestrial chemical weathering flux may be permanently altered--contrasting with the conventional v
24 manipulation of CB(1) cannabinoid receptors permanently alters cholinergic projection neuron identit
26 ut primary amino groups [R-NH2 ] and becomes permanently anchored via a tetrahedral iminosulfur(VI) l
27 nt protein were microinjected into the PB to permanently and selectively disrupt Vglut2 expression wh
28 her the selfie was shared temporarily versus permanently) and are instead driven by the disinhibition
29 ng a Sericomyrmex fungus-growing ant host, a permanently associated parasitic guest ant of the genus
30 ly, is the only member of this group that is permanently associated with the spliceosome, thus requir
33 5 and 8.5, but two leaks did not self-repair permanently at pH 11.0 suggesting that water chemistry m
34 aspartates in the C2A-domain localizes Doc2B permanently at the plasma membrane, and renders an upstr
37 the Oligocene (27 Mya), all parts of the JMM permanently became part of the Eurasian plate following
38 arctic clam Laternula elliptica lives almost permanently below 0 degrees C and therefore is a valuabl
41 actions, the unpaired cysteine-34 of HSA was permanently blocked by iodoacetamide and the primary ami
42 promote killing; and 3) surfaces containing permanently bonded agents that generate antimicrobial su
43 f cement proteins (CPs) that organize into a permanently bonded layer displayed as nanoscale fibers.
45 e is typically a monolithic integration that permanently bonds acoustic transducers with microfluidic
47 als can temporarily be carried off course or permanently carried away from their preferred habitat by
48 g to secondary interactions of the analytes' permanently charged quaternary ammonium head or hydropho
49 Hofmeister effects in Ca2+/Na+ exchange on a permanently charged surface over a wide range of ionic s
54 Ladahk were among the last habitable places permanently colonized by prehistoric humans due to the c
55 Sensory deprivation during these periods permanently compromises an organism's ability to perceiv
56 he results show that K4Nb6O17 nanolamina can permanently confine the toxic cations within the interla
59 r goal-directed movements, their accuracy is permanently controlled by adaptation mechanisms that, in
60 f this technology is that genome editing can permanently correct disease-causing mutations and circum
61 y and community composition of fungi in five permanently covered lake basins located in the Taylor an
63 hese advancements, achieving self-healing in permanently cross-linked hydrogels has remained elusive
68 or T cell production can be dramatically and permanently damaged after a single relatively low TBI do
69 marrow stroma cells (BMSCs) are severely and permanently damaged by the pre-conditioning irradiation
70 The affected joints are often rapidly and permanently damaged despite antibiotic treatment, indica
71 orter than drought recovery time, leading to permanently damaged ecosystems and widespread degradatio
74 l cortex, in which loss of vision to one eye permanently degrades cortical responsiveness to that eye
77 ts with short bowel syndrome (SBS) who were "permanently" dependent on parenteral nutrition (PN) and
78 using rhesus macaques (RMs) selectively and permanently depleted of CD4(+) T(N) before SIV infection
80 currently with peptide self-assembly without permanently destroying the hydrogel's architecture and r
81 Covalent capture of oxidized PTP1B could permanently disable the intracellular pool of enzyme inv
83 ial fibrillation patients who temporarily or permanently discontinued anticoagulation, the risk of st
84 brillation (RELY-ABLE) trial if they had not permanently discontinued study medication at the time of
89 onRI complexes, such allergic effector cells permanently display allergen-specific IgE on their surfa
90 ntensity monopolar pulsed electric fields to permanently disrupt cell membranes within a well-defined
93 rbing axon projection beyond postnatal day 7 permanently disrupts targeting specificity of the sensor
95 oma cells deficient for TF remain viable but permanently dormant at the injection site for nearly a y
96 arget genes independently of HOCl stress and permanently down-regulates intracellular iron levels.
98 T cells in which the CCR5 gene was rendered permanently dysfunctional by a zinc-finger nuclease (ZFN
99 ntified multiple pathways which appear to be permanently dysregulated in UC patients at formerly acti
100 the metastatic behavior of primary tumors by permanently 'educating' bone marrow progenitors through
103 esent strong evidence that WDPS females have permanently emigrated to the East, reproducing at two 'm
104 of triggering unrestrained proliferation of permanently engineered T cells raises safety concerns th
108 tion I: the initially formed wrinkles can be permanently erased and never reappear; and (3) irreversi
109 d that sexual phenotypes formed in utero are permanently established and do not require maintenance.
112 study has data for whether a child has been permanently excluded from school up to the age of 8 year
114 any cellular constituents in the human brain permanently exit from the cell cycle during pre- or earl
115 onal nuclei that reside in an aged brain had permanently exited from the cell cycle during prenatal d
116 ess, accumulated irreparable DNA damage, and permanently exited the cell cycle after transient exposu
118 ding site or a cytosolic tripeptide sequence permanently expose the alpha-arrestin-targeted region so
119 The ability to control T cells engineered to permanently express chimeric antigen receptors (CARs) is
120 andomly integrate into plant chromosomes and permanently express encoded transgenes, a process known
121 tent retroviruses can be used in axolotls to permanently express markers or genetic elements for func
122 r basal state, recognize transporter regions permanently facing the cytosol or unveiled during transp
123 ross-linking of the B compartments allows to permanently fixate the phase-separated state and dissolu
124 of note was that executive boards may not be permanently fixed as either unsupportive or supportive a
125 hology collections I show that nematodes are permanently fixed in shells for hundreds of years and th
126 nhancement, making PAiRFPs advantageous over permanently fluorescent probes for in vivo imaging condi
127 al and temporal sensitivity in comparison to permanently fluorescent small molecules, represent power
129 most common type of DNA damage, as they are permanently formed in living cells due to erroneous inse
130 geographic ranges of arctic megafauna became permanently fragmented after stable, interglacial climat
131 cumulation of fructose 1,6-bisphosphate in a permanently frozen solution as followed over months.
132 e argue that UV(254) treatment of aggregates permanently fused a fraction of viruses, which increased
134 that infection leads to the establishment of permanently growing lymphoblastoid cell lines, whereas C
135 leads to an accumulation of DNA damage that permanently halts beta-cell proliferation and dramatical
136 ugs, which bind with protein targets but not permanently, have been gaining attention because of thei
137 y share an allele at only one locus, or fuse permanently if they share an allele at both genes [5, 9]
139 es plants to establish a vegetative cover to permanently immobilize contaminants in the rooting zone,
140 elease, a histone H2B-Chk1 chimera, which is permanently immobilized in chromatin, is unable to promo
143 rbances in this process would be expected to permanently impact lung structure and might predispose t
144 e during adolescence, but not adulthood, may permanently impair cognition and increase the risk for p
147 gen-specific antibody responses but does not permanently impair their development or induce tolerance
151 g System (CardioMEMS, Atlanta, Georgia) is a permanently implantable pressure measurement system desi
153 electromechanical system pressure sensor was permanently implanted in all participants during right h
156 other sexual dimorphisms, drug metabolism is permanently imprinted by perinatal hormones, resulting i
157 or Ku expression, we found that cells arrest permanently in G2 phase when Ku expression is turned off
159 xhibited by nonswitching proteins, which are permanently in the on-state; when these bind to DNA nons
160 ereafter (time 3: cardiogenic shock excluded permanently) in New York and compared with Michigan.
161 uorescent protein expression, transiently or permanently, in cells that survive caspase-3 activation
162 ecision medicine strategy to selectively and permanently inactivate only mutant, not normal allele, c
166 unct PV neurons in the generation of TLE, we permanently inhibited GABA release selectively from PV n
170 d structures by external fields can be bound permanently into stiff chains through electrostatic or v
172 ently, transplantation experiments involving permanently labeled cells revealed multipotent neural st
174 ombination with a reporter mouse line (Ai9), permanently labels a cell population, termed 'SMA9'.
175 re)R26R(eYFP) mice, the fluorescent reporter permanently labels cells that have switched on Il22 expr
178 ay-old rat pups had the right carotid artery permanently ligated followed by 160min of hypoxia (8% ox
180 for independent movements of the digits was permanently lost after a complete, bilateral lesion of t
182 a afferent synapses and stretch reflexes are permanently lost, even after regeneration and reinnervat
186 we used an inducible Atoh1(CrePR) allele to permanently mark Atoh1-expressing cells at different dev
188 rowth of 97 199 individual trees within 1070 permanently marked inventory plots as a function of tree
189 facilitates the study of neural circuits by permanently marking cells active during user-specified t
190 facilitates the study of neural circuits by permanently marking cells active during user-specified t
191 itive moiety yields an "ion integrator" that permanently marks cells undergoing high Ca(2+) flux duri
192 glucocorticoid receptor and degradation of a permanently misfolded protein, two previously defined ro
193 pre-1950, most (74%) of the sea floor in the permanently mixed area off East Anglia was within the ph
194 ngs suggest that tumor endothelial cells are permanently modified compared with normal counterparts.
196 posons offer an efficient nonviral method of permanently modifying the genomes of mammalian cells.
198 inding mutants of kinesin-1 as roadblocks to permanently obstruct individual microtubule binding site
200 state, i.e. in the absence of DctA, DcuS is permanently "on", but its activity is C4-diC-dependent w
203 lanted for hereditary HLH (2000-2013) and DC permanently or transiently <75% (overall, CD3(+), CD56(+
205 ental factors, including air pollutants, may permanently organize these systems toward trajectories o
206 d inactivation, whereas a Cys residue can be permanently overoxidized to the sulfinic acid form, and
207 rasting depositional regimes: Zaka Bay, with permanently oxic bottom and station D, where anoxic cond
210 th large three-dimensional channels that are permanently porous and chemically stable offers new oppo
212 Zn2(TTFTB) represents the first example of a permanently porous MOF with high charge mobility and may
213 network is stable up to 425 degrees C and is permanently porous to CO(2) with an apparent BET surface
216 t organic frameworks (COFs) are crystalline, permanently porous, two-dimensional or three-dimensional
217 (i) stable to the removal of solvents, (ii) permanently porous, with surface areas of ~1200 m(2) g(-
220 ere, we used DcxCreER(T2) transgenic mice to permanently pulse-label age-defined cohorts of granule c
221 the recombinases can be layered and used to permanently record the transient state of a transcriptio
222 of an inactive, dsRNA-binding mutant can be permanently recorded by the input-responsive action of a
226 ple doses of ivermectin may cumulatively and permanently reduce the fertility and shorten the lifespa
228 least 2% of most populations and can lead to permanently reduced vision if not detected and treated w
229 uring pregnancy and lactation in mice, which permanently reduces endocannabinoid levels in the offspr
230 of older people (aged >/=65 years) who were permanently registered with a general practice in three
231 chemotherapeutic, gemcitabine, the treatment permanently remodels the tumor microenvironment and cons
232 The renewed effort to eliminate malaria and permanently remove its tremendous burden highlights ques
233 ecause of a continuous leak, Na(+) has to be permanently removed from the intracellular milieu, a pro
235 The creation of a transplantable graft to permanently replace kidney function would address donor
236 ed bacterial carbohydrates and phospholipids permanently reprograms the natural antibody repertoire d
240 ns' normal anterior-posterior pattern can be permanently rewritten by a brief perturbation of endogen
242 cessfully launch polio endgame activities to permanently secure and sustain the enormous gains of pol
243 e, which lack alphaCaMKII or which express a permanently self-inhibited alphaCaMKII (alphaCaMKII(T305
244 bind to a capture or competitor DNA strand, permanently separating it from the BHQ-modified reporter
247 t the lunar volatile inventory in the Cabeus permanently shadowed region includes a water concentrati
248 esigned to search for evidence of water in a permanently shadowed region near the lunar south pole.
250 tly impacts key developmental processes that permanently shape circuit function and behavior, as well
253 elopment when activity plays a large role in permanently shaping neural circuits, our data show how t
254 nn widget is incorporated into a website, it permanently shows timely relevant information as if it w
255 egulated subnuclear genome reorganization to permanently silence Hunchback target genes that results
256 K4me3 mark prevents the region from becoming permanently silenced and prepares the domain for activat
259 he previously intact side before UL remained permanently silent during natural vestibular stimulation
260 dipose expansion and during chronic obesity, permanently skewing the immune system to a proinflammato
264 large minority of resilient cooperators can permanently stabilize unravelling among a majority of ra
265 ferroelastic domains can be effectively and permanently stabilized by dislocations at the substrate
266 ion and transcription in the affected region permanently stall, so the failure of R-loop removal in R
269 olution depends on the ability to safely and permanently store CO2 This study demonstrates for the fi
270 to the atmosphere of C putatively considered permanently stored, thus challenging current models of l
271 e incremental oil from depleted fields while permanently storing large tonnages of injected CO2.
274 anscriptionally silenced in the syncytium to permanently suppress its activity during all nematode pa
275 lation, demonstrating that CD8(+) dT are not permanently suppressed and retain the capacity to respon
278 e by using a stable form of GFP (H2B-GFP) to permanently tag neurons that are active during contextua
279 blocks, the PEDOT chains are intimately and permanently tethered on the PbTe nanoparticle surface, t
280 rse ferroelectric nanoparticles directly and permanently tethered with ferroelectric polymers by capi
282 ocessable, and have limited ability to alter permanently their stress state, topography, topology, or
284 nests at the field site and sometimes moving permanently to new nests should that offer better (inclu
288 al upward ice transport, which may therefore permanently trap them below the ice surface and explain
289 ation appears to occur through Ede1, because permanently ubiquitinated Ede1 phenocopies deletion of U
290 enotypes could be replicated by expressing a permanently ubiquitinated version of Ede1, the yeast Eps
291 of yield, where a material changes its shape permanently under external deformation, are not yet unde
292 atients who stopped dosing at week 12 either permanently under the original protocol, or temporarily
293 poptotic pathways in effector T cells and by permanently upregulating their IL-7 receptor expression,
295 the minor antenna complexes were present in permanently weakly fluorescent states under most conditi
299 ill needlessly and potentially harm patients permanently without providing any significant benefit.
300 However, the influence of temperature was permanently written into tree-ring structure only for th
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