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1 and show that the apical membrane is highly permeable.
2 effects, suggesting that hPL is not membrane-permeable.
3 e TRPV1 pore, rendering the channel chloride-permeable.
4 We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearrang
7 Na2S enhanced CFTR stimulation by membrane-permeable 8Br-cAMP under inhibition of adenylyl cyclase-
9 mpound 5c has been identified as a promising permeable agent showing excellent antioxidant properties
12 ore synapses through incorporation of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole pro
13 common nucleus accumbens (NAc) shell calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazoleprop
14 its permeation through Ca(2+)- (and Zn(2+))-permeable AMPA channels in CA3 and Zn(2+) mobilization f
15 TNFalpha triggers the upregulation of Ca(2+)-permeable AMPA receptor (CP-AMPAR) expression in RGCs of
16 -term potentiation (LTP) and inserts calcium permeable AMPA receptor (CP-AMPAR) for variable periods.
17 rawal from this regimen; furthermore, Ca(2+)-permeable AMPA receptors (CP-AMPARs) increase in the NAc
18 rawal from this regimen; furthermore, Ca(2+)-permeable AMPA receptors (CP-AMPARs) increase in the NAc
19 ransport of GluA1 subunit-containing calcium-permeable AMPA receptors (CP-AMPARs) to synapses in subr
20 STN synapses showed a decrease in calcium-permeable AMPA receptors after cocaine, but no change in
21 ntiation and selective antagonists of Ca(2+)-permeable AMPA receptors also blocked the potentiation o
22 eptors but requires co-activation of Ca(2+) -permeable AMPA receptors and group I metabotropic glutam
23 s, an enhanced relative expression of Ca(2+)-permeable AMPA receptors at muscle afferent synapses dri
24 esults suggest that Ca(2+) influx via Ca(2+)-permeable AMPA receptors can elicit a rapid form of post
25 (and experiments verified) that fast calcium-permeable AMPA receptors enable basket cells to respond
26 coupled to removal of high-conducting Ca(2+)-permeable AMPA receptors from synapses, resulting in syn
28 In the present study, we looked for calcium-permeable AMPA receptors in two distinct populations of
32 lencing/maturation by recruitment of calcium-permeable AMPA-type glutamate receptors (CP-AMPARs) afte
35 on, eating 'junk-food' increased NAc calcium-permeable-AMPAR (CP-AMPAR) function only in obesity-susc
37 structural evidence for GluA2-lacking Ca(2+)-permeable AMPARs (CP-AMPARs) at the mature hair cell rib
38 ivergent species, we demonstrate that Ca(2+)-permeable AMPARs (CP-AMPARs) mediate glutamatergic trans
40 synaptic expression of GluA2-lacking Ca(2+)-permeable AMPARs, contributing to toxic Ca(2+) influx.
41 and promoting synaptic expression of Ca(2+)-permeable AMPARs, which in turn induced a previously uni
45 ed, selective activation of Epac by the cell-permeable analog 8-(4-chlorophenylthio)-2'-O-methyladeno
47 at was accompanied by an increase in calcium-permeable and calcium-impermeable AMPARs, respectively.
48 d to imaging acidic tissues, delivering cell-permeable and impermeable molecules to the cytoplasm, an
51 ics of two uncharged derivatized sugars, one permeable and one impermeable, through a validated conne
52 the blood-brain barrier (BBB), a selectively permeable and protective interface between the brain and
54 o the periplasm to oxidize the more membrane-permeable and toxic Cu(I) before it can enter the cytopl
55 ease resistant, structurally rigid, membrane permeable, and capable of modulating protein-protein int
57 microvasculature tends to be malformed, more permeable, and more tortuous than vessels in healthy tis
58 low deactivation kinetics, are highly Ca(2+) permeable, and require depolarization to relieve channel
59 Hsp90 inhibitors are not blood-brain barrier-permeable, and several present associated toxicities.
61 s was confirmed via calculation of the total permeable area created by the micropores (which would ap
62 ounterintuitively, we find that reducing the permeable area of an ion exchange membrane, with appropr
64 e report the first predictive model for cell permeable background-free probe development through opti
65 umnar epithelial cells that forms a dynamic, permeable barrier allowing for selective absorption of n
67 of wellbore cement, the cement becomes less permeable because of carbonate mineral precipitation wit
68 This strategy was applied to generate a cell-permeable bicyclic peptidyl inhibitor against the NEMO-I
70 terrestrial ecosystems are characterized by permeable boundaries that are crossed by resource subsid
71 elucidate the coupled effects of the highly permeable, but heterogeneous tumor vasculature, with the
73 with high propensity to extravasate across a permeable capillary endothelial barrier, but not with ga
75 r Potential Melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel essential for immunocyte activa
76 tential canonical type 5 (TRPC5) is a Ca(2+)-permeable cation channel that is highly expressed in the
77 tential 6 (TRPC6), a nonselective and Ca(2+)-permeable cation channel, mediates pathophysiological re
78 ass of NAADP- and PI(3,5)P2-sensitive Ca(2+)-permeable cation channels in the endolysosomal system of
79 ial (TRP) proteins form a superfamily Ca(2+)-permeable cation channels regulated by a range of chemic
82 one isoform, AtMCU1, gives rise to a Ca(2+)-permeable channel activity that can be observed even in
83 tial canonical channel-1 (TRPC1) is a Ca(2+)-permeable channel found in key metabolic organs and tiss
84 agonist and modulator complex harbors an ion-permeable channel gate, providing the first view of an a
89 (ANN1), which was reported to form a calcium-permeable channel that contributes to the NaCl-induced [
92 dilation model, ATP binding opens an NMDG(+)-permeable channel within milliseconds, with a conductanc
93 ptor potential canonical 3 (TRPC3), a Ca(2+)-permeable channel, acts as a positive regulator of ROS (
94 We fused CaV1.2 to a ligand-gated Ca(2+)-permeable channel, enabling independent control of local
95 channels form a complex with the postassium-permeable channel, which modulates nuclear Ca(2+) releas
99 w that GLR genes encode non-selective Ca(2+)-permeable channels that can regulate cytoplasmic Ca(2+)
100 nnexins, which can form mechanosensitive ATP-permeable channels, are present in human dental pulp.
103 with newly developed, freely diffusing, cell-permeable chemical probes with targeted affinity for DNA
106 ities for the rational design of future cell-permeable compounds and for the optimization of delivery
111 these silent synapses via recruiting calcium-permeable (CP) AMPARs contributes to incubation of cocai
113 lacking an edited GluA2 subunit are calcium-permeable (CP) and contribute to synaptic plasticity in
114 , using CSD mutants (F92A/V94A) and membrane-permeable CSD-competing peptides, that Src kinase-depend
116 g-chain acyl-coenzyme A synthetase2 (lacs2), permeable cuticle1 (pec1), cyp77a6, glycerol-3-phosphate
117 phosphodiesterase 3B (PDE3B), and a membrane-permeable cyclic guanosine monophosphate (cGMP) analog o
118 discovery of geometrically diverse, membrane permeable cyclic peptide scaffolds based on the synthesi
119 utic effect of an orally bioactive and brain permeable delta-secretase inhibitor in mouse models of A
120 utility of this chemistry in creating a cell-permeable derivative of a high-affinity HIV Rev protein-
121 ipulating actin dynamics are limited to cell-permeable drugs that preclude single-cell perturbations.
124 elling method based on the organic, membrane-permeable dyes SiR and ATTO590 as Halo and SNAP substrat
125 ible photonic structure that is encased by a permeable envelope which mediates liquid-induced colour
127 during hyperammonaemia, and providing a cell-permeable ester of alphaKG reversed the lower TCA cycle
131 4,5-diaminofluorescein diacetate, a cell-permeable fluorescent molecule, was used to detect chang
132 rted a general method to improve small, cell-permeable fluorophores which resulted in the azetidine-c
133 zone diameter of congruent with1.4 nm and is permeable for glucose, glucose 1-phosphate and glucose 6
134 ng a diffusion barrier, which is selectively permeable for nuclear transport receptors that interact
135 ructural requirements rendering certain AQPs permeable for weak monoacids and the mechanism of conduc
139 ts on both cell volume homeostasis and Cl(-)-permeable GABAA receptor-dependent membrane excitability
141 ration of the analyte from the sample with a permeable gas diffusion membrane and its indirect detect
144 f unedited GRIA2 subunits leads to a calcium-permeable glutamate receptor, which can promote cell mig
145 ,096 known compounds identified two membrane permeable GO inhibitors: dichromate salt and colistimeth
147 carbon pool contains more of the highly cell-permeable H2CO3, necessitating a substantial expenditure
149 ch transactivation complex by using the cell-permeable, hydrocarbon-stapled synthetic peptide stapled
150 emonstrated by incorporating 1.Eu into water-permeable hydrogels that can be utilized as an alternati
151 of C. difficile spore germination and poorly permeable in a Caco-2 model of intestinal epithelial abs
153 By establishing 5-nitroisatin as a cell-permeable inhibitor for Torsin processing, we provide th
154 xpression, yet there are few selective, cell-permeable inhibitors or suitable tool compounds for thes
155 k-in mouse lacking the PDZ motif, and a cell-permeable interfering peptide, we found that this mechan
156 ester)phenylphosphine borane complex, a cell-permeable intracellular disulfide-reducing drug, slowed
158 7 (TRPM7) is a ubiquitously expressed Mg(2+)-permeable ion channel fused to a C-terminal alpha-kinase
161 The role of mechanosensitive (MS) Ca(2+)-permeable ion channels in platelets is unclear, despite
162 a(2+) source, either from influx via calcium permeable ion channels on plasmic membrane or release fr
163 eptors (NMDARs) are glutamate-gated, calcium-permeable ion channels that mediate synaptic transmissio
165 hich sets the driving force for the chloride-permeable ionotropic GABAA receptor in mature neurons.
166 Activation of most representative Ca(2+)-permeable ionotropic receptors similarly regulate T-type
167 and shear stress profiles for flow over the permeable layer for the limiting cases of alpha --> 0 an
172 how specific IDPs can phase separate to form permeable, low-density (semi-dilute) liquids, whose stru
173 tion of the first class of oxadiazole-based, permeable macrocyclic inhibitors of norovirus 3CL protea
174 ater and nutrients, and the elastomer is air-permeable, maintaining long-term viability and functiona
175 rs that are GluA2-subunit lacking and Ca(2+) permeable, making them distinct from AMPA receptors at m
176 es were built with walls made of lightweight permeable materials (bamboo, shade net, or timber) with
177 stem distinguishes opaque surfaces and light-permeable materials and why discrepancies arise between
179 re-scale dynamics of two-phase fluid flow in permeable media is important in many processes such as w
180 ols the displacement of immiscible fluids in permeable media, with far reaching implications for stor
181 force distance curves also exhibited a more permeable membrane for CYnLIP-incubated skin than hydrat
182 r leads to opening of the characteristic dye-permeable membrane pore for molecules up to 900 Da.
184 are, OECTs have not been integrated in thin, permeable membrane substrates for epidermal electronics.
185 hwater rainbow trout gill epithelium on flat permeable membrane supports within cell culture inserts.
186 ulated by means of ultrafiltration over semi-permeable membrane with a molecular weight cut-off of 5
190 r a ubiquitous, pernicious trade-off: highly permeable membranes lack selectivity and vice versa.
191 nting engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold.
192 e lattice to create mechanically robust, gas-permeable membranes, and direct printing of micron-scale
197 for a more soluble equivalent led to a cell-permeable molecule that selectively and efficiently bloc
200 Bleeding and vascular complications, using permeable nitinol cardiac occluders to close the access
202 tor potential canonical 5 (TRPC5), a calcium-permeable, non-selective cation channel is expressed in
203 influx of the divalent ion via more Ca(2+) -permeable normal MT channels inhibits the anomalous chan
204 rs, including those able to desensitize, are permeable not only to NMDG(+) but also to spermidine, a
206 are proteinaceous intracellular organelles, permeable only to gas, that enable flotation in aquatic
207 torage facilities, type of packaging (oxygen-permeable or not), and premix composition (with or witho
209 ncreased by increasing GSH adducts with cell-permeable oxidized GSH (GSSG-ethyl ester) or 2-acetylami
216 Moreover, an exogenously applied membrane-permeable peptide that competes for Tau-vesicle binding
218 ethyl and d-amino acids to produce passively permeable peptides, which contain multiple polar residue
221 enic peptide nucleic acid probes embedded in permeable, physically crosslinked, alginate beads were a
223 st cancers that overexpress specific calcium permeable plasmalemmal ion channels with available selec
226 his challenge by incorporating a biomolecule-permeable polymer layer on the surface of silicon nanowi
227 oluble polymethyloxazoline shells and oxygen-permeable polystyrene cores crosslinked with metal-free
228 tuted into liposomes, forms an intrinsic dye-permeable pore in the absence of other cellular componen
229 onstitutes a lipid-composition dependent dye-permeable pore, whose opening is facilitated by palmitoy
230 ns (eg, claudin-4) as receptors to form Ca2+-permeable pores in the membrane, damaging epithelial cel
231 reflects an interplay among multiple Ca(2+) permeable pores with distinct electrophysiological prope
234 roelectrode array is covered with a layer of permeable porous polymethacrylate functionalized with a
235 enyl diphosphate (HMBPP) or a synthetic cell-permeable prodrug, bis (pivaloyloxymethyl) (E)-4-hydroxy
237 rget biological analytes through use of cell-permeable profluorogenic probes is dependent on the avai
239 enzymatic core encapsulated in a selectively permeable protein shell; prominent examples include the
241 potential of zerovalent-iron- (Fe(0)) based permeable reactive barrier (PRB) systems for arsenic (As
242 ition to increase the contribution of Ca(2+)-permeable receptors (CP-AMPARs) containing GluA1 but lac
243 creased permeability, a is the radius of the permeable region, and D is the solute diffusion coeffici
244 tem that utilizes a light-programmable, cell-permeable reporter deliverable simultaneously to many ce
245 ll uptake properties of a dinuclear membrane-permeable Ru(II) cell probe show that, at low concentrat
246 We image the flow of N2 and brine through a permeable sandstone at subsurface reservoir conditions,
247 brary, followed by deconvolution of membrane-permeable scaffolds to identify cyclic peptides with goo
252 HIDE) membrane probes, based on the membrane-permeable silicon-rhodamine dye HMSiR, that assemble in
253 oxygen species (ROS) state, whereas the more permeable sinusoids promote HSPC activation and are the
254 elective release in the liver of a passively permeable small-molecule cargo was achieved by retro-Die
255 velopment of DI-591 as a high-affinity, cell-permeable small-molecule inhibitor of the DCN1-UBC12 int
257 ed on the reaction of AMD with calcite-based permeable substrates followed by decantation ponds.
258 tively, 2-dimensional HAT-7 cell cultures on permeable supports 1) form tight junctions, 2) express t
259 able transepithelial resistance on Transwell permeable supports and expressed claudin-1, claudin-4, a
262 ate or heptadecanoyl heptadecanoate are less permeable than pure 1,2-dipalmitoyl-sn-glycero-3-phospha
263 tial vanilloid 3 (TRPV3) channel is a Ca(2+)-permeable thermosensitive ion channel widely expressed i
265 To test whether 6-CF was transported through permeable TJ, we intravenously injected low molecular we
267 el made from 20% to 30% of PEG700 monomer is permeable to amino acids yet impermeable to oligopeptide
270 are located at the nuclear envelope and are permeable to Ca(2+) We demonstrate that the cyclic nucle
272 swelling-activated chloride channel that is permeable to inorganic anions and a variety of small org
275 has an exceptionally wide filter but is only permeable to monovalent cations; filter residue Gln973 i
279 ties of these two polymer materials: PDMS is permeable to O2 and the presence of O2 inhibits the poly
280 tochondrial membrane becomes depolarized and permeable to osmolytes, proposedly due to the opening of
282 enabling long term study, and is selectively permeable to small molecules including antibiotics, sign
284 y tuned concentrations to render RBCs highly permeable to substrates, while low concentrations of glu
285 modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plas
287 to water in normal animals but become highly permeable to water in Ildr1 knockout animals whereas par
289 renal protection by down-regulating calcium-permeable transient receptor potential canonical type is
290 In barley (Hordeum vulgare), the root anion-permeable transporter Bot1 plays a key role in tolerance
291 ssion may favour formation of highly Ca(2+) -permeable TRPC4-containing channels that promote transfo
297 rens intercellular junctions and became more permeable when cultured on stiffer substrates in the pre
298 o enhance NPC migration, we generated a cell-permeable wild-type p38 protein (PTD-p38WT) in which the
299 rable labelling probes should be highly cell permeable without nonspecific interactions with other ce
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