ライフサイエンスコーパス: permease

1 on and encode a putative membrane-associated permease.

2 on protein, YknY is an ATPase, and YknZ is a permease.

3 activity with the broad specificity mannose permease.

4 phosphate-binding cassette (ABC) transporter permease.

5 receptor, ComR, after uptake by oligopeptide permease.

6 ular hinge between the two halves of lactose permease.

7 ne is located in a hydrophobic region of the permease.

8 ve structural model based on E. coli lactose permease.

9 scriptional repressor of the NikABCDE nickel permease.

10 he cytoplasm from the periplasm via the AmpG permease.

11 facilitator transporter superfamily, lactose permease.

12 T456S and S176N convert Can1 to a Lyp1-like permease.

13 ransfer it to its cognate inner membrane ABC permease.

14 n of not only Trk1 but also several nutrient permeases.

15 romise with suboptimal activity for most PTS permeases.

16 endent sugar:phosphotransferase system (PTS) permeases.

17 membrane domain protein with homology to ion permeases.

18 cells with a small number of membrane-bound permeases.

19 f the nutrient scavenging general amino acid permease 1.

20 The Ureide Permease 5 (UPS5) is expressed in the cortex and endoder

21 scherichia coli PTR dipeptide and tripeptide permease A (DtpA), which shows substrate specificities s

22 the five annotated homologs of oligopeptide permease A (OppA5, BBA34).

23 ermease (biofilm and endocarditis-associated permease A [BepA]), as important in infective endocardit

24 Amino acid permeases (AAPs) in the plasma membrane (PM) of Saccharo

25 M. catarrhalis has a putative oligopeptide permease ABC transport operon (opp) consisting of five g

26 hreshold, and abolishes bistability at large permease activities, a conclusion that can be tested exp

27 Potassium, but not chloride, permease activity required the presence of calcium ions

28 the lac operon that minimize the cost of lac permease activity, not protein expression.

29 Instead, we discovered that the lac permease activity, which relates linearly to cost, is th

30 of the cel regulon, but loss of specific PTS permeases alleviated repression of cel genes in the pres

31 s, a defect in the trafficking of the uracil permease, alpha-syn accumulation and foci, and a slow gr

32 idis recycles PG fragments via the selective permease AmpG and that meningococcal PG recycling is mor

33 tinct domains: a membrane-anchored metal ion permease and a diphtheria toxin repressor (DtxR)-like tr

34 osine and uridine uptake mediated by the NT1 permease and also induced up to a 200-fold enhancement i

35 All LIV permease and ATPase components were dispensable for in v

36 dentify these proteins, mutants of candidate permease and ATPase genes were generated allowing for ch

37 results provide the first description of the permease and ATPase proteins required for the import of

38 cus tag: SO_1522-SO_1518) containing lactate permease and candidate genes for both d- and l-lactate d

39 Mutants lacking the FpuB permease and FatE ATPase (DeltafpuBDeltafatE) and a muta

40 incided with a reduction in putative sulfate permease and not sulfate adenylyltransferase transcripts

41 diacylglycerol 1 (TGD1) and TGD2, encode the permease and substrate binding component, respectively,

42 thway (sugar-phosphotransferase system [PTS] permease and sucrose-6-PO(4) hydrolase) constitute the m

43 notype with the activity of the auxin intake permease and suggests that MED12 acts upstream of AUX1 i

44 ligand-binding component of an ABC-type zinc permease and that perturbation of zinc homeostasis inhib

45 FsrA also represses the DctP dicarboxylate permease and the iron-sulfur-containing enzyme glutamate

46 ndocytosis by interacting with both a client permease and the ubiquitin ligase Rsp5.

47 for a heterodimeric pair of ABC transporter permeases and may code for part of a new pathway for syn

48 consists of ddT transport by host nucleoside permeases and phosphorylation to ddTMP by the host thymi

49 ese data, a model for the involvement of PTS permeases and the general PTS proteins enzyme I and HPr

50 ed lipid transporter consisting of the TGD1 (permease) and TGD3 (ATPase) proteins.

51 the inducer enters the cell via the carrier (permease), and exits by a diffusion-like process.

52 , arsP that encodes the ArsP MAs(III) efflux permease, and arsH encoding the ArsH MAs(III) oxidase.

53 ogic machines, such as ATP synthase, lactose permease, and G-protein-coupled receptors.

54 t encodes a ferric hydroxamate uptake system permease, and propose that the norA transcription is iro

55 e mapped to a topological model of the hFbpB permease, and the implications of mutations are discusse

56 nnose family phosphotransferase system (PTS) permease, and we designate the genes encoding the permea

57 ed by well studied xanthine and/or uric acid permeases, and COG2252, consisting of transporters for a

58 imensional structure exists for any of these permeases, and they are not present in prokaryotes, the

59 topology, stability and function of lactose permease are found to have different dependences on bila

60 These permeases are known to positively affect sporulation in

61 ox because five putative carbohydrate uptake permeases are present in Mtb, but there are essentially

62 Interestingly, TbPT family permeases are related to polytopic proteins from plants

63 that regulates the expression of amino acid permeases, are impaired in multiple aspects of fungus-ma

64 A bacterial permease, ArsP, from Campylobacter jejuni, was recently

65 athway of Gap1 down-regulation targets other permeases as well, and it likely allows cells facing adv

66 hal5 growth defects by stabilizing nutrient permeases at the plasma membrane.

67 f unknown function adjacent to the canonical permease, ATPase, and solute-binding protein (SBP) genes

68 two-hybrid analyses and could show that the permease BceB and the histidine kinase BceS interact dir

69 analyzed substrate binding by the transport permease, BceB.

70 Permeases belonging to the equilibrative nucleoside tran

71 Therefore, we propose that the PTS permease BepA is directly implicated in E. faecium patho

72 carbohydrate phosphotransferase system (PTS) permease (biofilm and endocarditis-associated permease A

73 roposal that HPr is not optimal for most PTS permeases but instead represents a compromise with subop

74 se permease (MelB), supporting the idea that permeases can differ in their thermodynamic response to

75 ificity of the H(+)-driven arginine-specific permease Can1.

76 the Crithidia fasciculata inosine-guanosine permease CfNT2 to facilitate biochemical studies using t

77 nd to iron limitation by expressing the iron permease CgFtr1 primarily on the cell membrane, and to i

78 e ATPase(s) interacting with each individual permease channel.

79 structure and function of the hFbpB membrane permease component of the transporter, a protein that ha

80 s: SmbF (the ATPase component) and SmbT (the permease component).

81 ng the permease dgaABCD (d-glucosaminate PTS permease components EIIA, EIIB, EIIC, and EIID).

82 Deletions of Hup permease components hupD, hupG or hupDGC reduced Hn/Hb u

83 uired the binding protein and inner membrane permease components of its overall transport system; pos

84 genome neighborhoods encoded SBPs as well as permease components of the TRAP transporters, members of

85 Members of the Acr3 family of arsenite permeases confer resistance to trivalent arsenic by extr

86 nally, we show for the first time that HrtBA permease controls heme toxicity by its direct and specif

87 hat we tested, the expression of the lactose permease could be costly or beneficial, depending on the

88 r data establish that bbb22-23 encode purine permeases critical for B. burgdorferi mammalian infectiv

89 Herein, TM organization of sucrose permease (CscB) and phenylalanine permease (PheP) as a f

90 -galactosidase from the cytoplasm of lactose permease-deficient E. coli ML-35.

91 Expression of AUX1 in a permease-deficient vat3 mutant resulted in increased net

92 erse conditions to retrieve amino acids from permease degradation.

93 A mutant strain lacking both permeases, DeltafpuBDeltafatCD, was incapable of using p

94 Potentially similar ammonium permease-dependent regulatory cascades operate in other

95 ase, and we designate the genes encoding the permease dgaABCD (d-glucosaminate PTS permease component

96 Moreover, the unusual membrane permease-DNA-binding polypeptide fusion configuration wa

97 er SYG1, Pho81 and XPR1) domain and an anion permease domain.

98 cells maintained in rich media and nutrient permease downregulation in yeast.

99 Furthermore, cell-free synthesis of lactose permease during DIB formation also results in active tra

100 ecific sugar phosphotransferase system (PTS) permease (EII(Cel)).

101 The glucose- and lactose-PTS permeases, EII(Man) and EII(Lac), respectively, were sho

102 tansenzyme II (EII(Lev)), a fructose/mannose permease encoded by the levDEFG genes, and fruA, which e

103 hic allele of rhb1(+) dramatically increased permease expression levels in Deltabhd but not in wild-t

104 ized yeast to rapamycin-induced increases in permease expression levels, and rapamycin induced lethal

105 repressor from DNA result in large bursts of permease expression that trigger induction of the lac op

106 As a membrane permease, Fcy2 may mediate limited cisplatin transport b

107 gh both hephaestin (Hp) and the ferrous iron permease ferroportin (Fpn) have been identified in BMVEC

108 sphatidylethanolamine lipids, lowers lactose permease folding and reconstitution yields but stabilise

109 rter for fructose (Frt), a major facilitator permease for glucose (GlcP), and a porin needed for the

110 he requirement of a putative ABC transporter permease for intracellular survival in macrophages.

111 ty and subsequently release it to a membrane permease for translocation into the cytoplasm.

112 Four encoded putative transporters or permeases for gamma-amino acids or drugs.

113 is and showed that they encode high affinity permeases for the uptake of adenine (PurP and YicO) or g

114 Either of two distinct permeases, FpuB or FatCD, is required for iron acquisiti

115 Crystal structures of lactose permease from Escherichia coli (LacY) exhibit two six-he

116 tures of both a mutant and wild-type lactose permease from Escherichia coli (LacY) in an inward-facin

117 f the NCS1 family, the Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to

118 r such a transporter, the LdNT1.1 nucleoside permease from the parasitic protozoan Leishmania donovan

119 r such a transporter, the LdNT1.1 nucleoside permease from the parasitic protozoan Leishmania donovan

120 is generally accomplished by arsenite efflux permeases from Acr3 or ArsB unrelated families.

121 ity with the glycerol-3-phosphate and fucose permeases from Escherichia coli, respectively.

122 EfeU is homologous to the high-affinity iron permease, Ftr1p, of Saccharomyces cerevisiae and other f

123 ecificity towards Fe(2)(+) and a ferric iron permease, Ftr1p, which supports Fe-accumulation.

124 mmetry motifs in the Escherichia coli fucose permease (FucP) results in remarkable homology to lactos

125 organic Pi transporter, Glycerol-3-phosphate permease (G3Pp) family, comprising five members (AtG3Pp1

126 replaced by increased expression of the GalP permease (galP) and glucokinase (glk).

127 Galactose permease (GalP) is the closest bacterial homolog of huma

128 For instance, the general amino acid permease Gap1 transports all amino acids, whereas Can1 a

129 racellular sorting of the general amino acid permease Gap1.

130 The high capacity general amino acid permease, Gap1p, in Saccharomyces cerevisiae is distribu

131 llular trafficking of the general amino acid permease, Gap1p, of Saccharomyces cerevisiae is regulate

132 The high affinity iron permease gene (FTR1) is required for R. oryzae iron tran

133 esis in Staphylococcus aureus, the glutamine permease gene (glnP) was inactivated and TCA cycle activ

134 repressing the adjacent phosphate-responsive permease gene transporter for glycerophosphodiester 1 (t

135 lncRNA transcription upstream of the tgp1(+) permease gene.

136 polycistronic with the upstream oligopeptide permease genes (opp1ABCDF), which encode an ABC oligopep

137 p295) (P = 0.003) and two glycerol transport permease genes (potA [mhp380; P = 0.006] and ugpA [mhp38

138 G, argH and argJ) and two arginine/histidine permease genes (SSA_1568 and SSA_1569) were upregulated

139 and rafEFG (raffinose substrate binding and permease genes), and both glucose and sucrose inhibited

140 unced for the highly expressed NCR-regulated permease genesGAP1,MEP2,DAL5,PUT4, andDIP5 Our results r

141 his report, we characterize this schistosome permease heavy chain (SPRM1hc) gene and protein.

142 sence of a heterologous plasma membrane heme permease (HRG-4), but the mode of suppression mediated b

143 ng of another gene involved in resistance, a Permease-I like protein, did not affect the expression o

144 ined the topological organization of lactose permease in an Escherichia coli model cell system in whi

145 he first evidence of an intracellular purine permease in apicomplexan parasites and suggests a novel

146 of the YtgR domain from a membrane-anchored permease in C. trachomatis could represent a previously

147 eisseria spp., the importance of the lactate permease in colonization of the host has been demonstrat

148 Lactose permease in Escherichia coli (LacY) transports both anom

149 transporter 1.1 (LdNT1.1) that captured this permease in the outward-closed conformation, and we iden

150 teria, we discovered that inactivating these permeases in C. difficile resulted in the earlier expres

151 ing necessary for transport catalysed by MFS permeases in general.

152 components, and certain fructose/mannose-PTS permeases in the transcriptional regulation of the cel l

153 ular sorting of Gap1, the general amino acid permease, in response to nutrients.

154 nd Tor2 inhibition leads to up-regulation of permeases including those that are regulated by Bhd.

155 IIA(Glc) is a negative regulator for several permeases, including the maltose transporter MalFGK2.

156 Facilitator Superfamily transporter, lactose permease, into Droplet Interface Bilayers and demonstrat

157 ransduction proteins, metabolic enzymes, and permeases involved in nitrogen assimilation.

158 transduction proteins, metabolic enzymes, or permeases involved in nitrogen metabolism.

159 It is believed that sugar binding to the permease is involved in an induced fit mechanism, and th

160 tant defective in a putative ABC transporter permease is resistant to both streptococcus/nitrite- and

161 y depleting glucose from the medium, and the permease is strongly down-regulated when flagellated ins

162 Therefore, the topology of both permeases is dependent on PE.

163 Gap1, the yeast general amino acid permease, is a convenient model for studying how the int

164 The lactose permease (LacY) catalyzes coupled stoichiometric symport

165 The lactose permease (LacY) catalyzes galactoside/H(+) symport via a

166 x bundles on the periplasmic side of lactose permease (LacY) cause complete loss of transport activit

167 ty (K(d)(app)) of purified wild-type lactose permease (LacY) for sugars was studied.

168 ribe an x-ray structure of wild-type lactose permease (LacY) from Escherichia coli determined by mani

169 According to x-ray structure, the lactose permease (LacY) is a monomer organized into N- and C-ter

170 gy-independent downhill transport by lactose permease (LacY) is impaired when expressed in Escherichi

171 N-terminal half of Escherichia coli lactose permease (LacY) is inverted with respect to the C-termin

172 The lactose permease (LacY) of Escherichia coli catalyzes stoichiome

173 In vivo lactose permease (LacY) of Escherichia coli displays a mixture o

174 Lactose permease (LacY) of Escherichia coli is an archetypal mem

175 The lactose permease (LacY) of Escherichia coli, a paradigm for the

176 Lactose permease (LacY) of Escherichia coli, when reconstituted

177 Based on the crystal structure of lactose permease (LacY) open to the cytoplasm, a hybrid molecula

178 X-ray crystal structures of lactose permease (LacY) reveal pseudosymmetrically arranged N- a

179 Sugar/H(+) symport by lactose permease (LacY) utilizes an alternating access mechanism

180 Lactose permease (LacY), a paradigm for the largest family of me

181 Lactose permease (LacY), a paradigm for the largest family of me

182 of Escherichia coli is catalyzed by lactose permease (LacY), which uses an alternating access mechan

183 P) results in remarkable homology to lactose permease (LacY).

184 s to a plant-specific class of purine uptake permease-like transporters that originated after the bry

185 ed for expression of genes encoding a malate permease (maeP) and malic enzyme (maeE).

186 Further, the Sap translocator permease mediated heme transport into the bacterial cyto

187 The bacterial melibiose permease (MelB) belongs to the glycoside-pentoside-hexur

188 Melibiose permease (MelB) is one among several permeases subject t

189 ITC differs from the inhibition of melibiose permease (MelB), supporting the idea that permeases can

190 The ammonium permease Mep2 is required for the induction of pseudohyp

191 he peptide transporter Ptr2 and the ammonium permease Mep3 as Syp1 cargoes containing DxY motifs.

192 ibe the details known for examples of uptake permeases, metallochaperones and proteins involved in me

193 ells is mediated by about 16 plasma membrane permeases, most of which belong to the amino acid-polyam

194 argeted at residues within the two conserved permease motifs were generated.

195 ent the molecular features in the methionine permease Mup1 that are required for Art1-Rsp5-mediated u

196 l, suggesting that one of the two nucleobase permeases must be retained for robust growth of the para

197 the presence of fucose, although its fucose permease mutant (fucP) shows no change.

198 Pase mutants were generated in either of the permease mutant backgrounds to identify the ATPase(s) in

199 dies using E. coli or C. glutamicum arsenite permease mutants clearly show that CgAcr3-1 is specific

200 To study the roles of the four purine permeases NT1-NT4 in Leishmania major, null mutants in e

201 iana tabacum gene encoding a nicotine uptake permease (NUP1).

202 d through a crystal structure of the lactose permease of E. coli (LacY), manually adjusted, and energ

203 The lactose permease of Escherichia coli (LacY) is a highly dynamic

204 The lactose permease of Escherichia coli (LacY) is a highly dynamic

205 lines of evidence indicate that the lactose permease of Escherichia coli (LacY) is highly dynamic an

206 WT lactose permease of Escherichia coli (LacY) reconstituted into p

207 nt (Gly46-->Trp/Gly262-->Trp) of the lactose permease of Escherichia coli (LacY) with a bound, high-a

208 Lactose permease of Escherichia coli (LacY) with a single-Cys re

209 enesis, insertion and folding of the lactose permease of Escherichia coli (LacY), a 12-transmembrane

210 The lactose permease of Escherichia coli (LacY), a highly dynamic me

211 The lactose permease of Escherichia coli (LacY), a highly dynamic po

212 ed for sugar-binding affinity to the lactose permease of Escherichia coli (LacY), indicating that, un

213 The melibiose permease of Escherichia coli (MelB) catalyzes the couple

214 We previously established that lactose permease of Escherichia coli displays a mixture of topol

215 -transmembrane domain (TM) bundle of lactose permease of Escherichia coli is uniformly inverted when

216 the galactoside/H(+) symporter LacY (lactose permease of Escherichia coli) are irreplaceable for an a

217 X-ray crystal structures of LacY (lactose permease of Escherichia coli) exhibit a large cytoplasmi

218 The melibiose permease of Salmonella enterica serovar Typhimurium (Mel

219 tal structure of the Na(+)-coupled melibiose permease of Salmonella enterica serovar Typhimurium (Mel

220 The melibiose permease of Salmonella typhimurium (MelB(St)) catalyzes

221 The MelB permease of Salmonella typhimurium (MelB-ST) catalyzes t

222 d in TMAO metabolism, including Msil_3606, a permease of the amino acids-polyamine (APC) superfamily,

223 a putative transcription factor and a sugar permease of the phosphotransferase system (PTS), which a

224 apBC mutant, which lacks both inner membrane permeases of the Sap transporter, and tested the mutant

225 the LmGT4 permease (previously called the D2 permease), on a circular extrachromosomal element, and t

226 mutation in fucP (encoding a putative fucose permease), one of the genes in the plasticity region, we

227 The oligopeptide permease (opp) ABC transport system is a nutritional vir

228 The B. burgdorferi oligopeptide permease (Opp) is one of only a few transporters encoded

229 gated the role of two conserved oligopeptide permeases, Opp and App, in the regulation of sporulation

230 ispanning membrane proteins such as mannitol permease or TatC, which had been considered to be exclus

231 of the FCY2 gene, encoding a purine-cytosine permease, or the HPT1 gene, encoding the hypoxanthine gu

232 ased on multiple-sequence alignments between permease orthologs, a series of site-directed mutations

233 the ATP-binding cassette (PA14_57880) or the permease (PA14_57870) produced substantially less extrac

234 bined activity of Smf3p and the ferroxidase, permease pair of proteins, Fet5p and Fth1p.

235 The 4-hydroxybenzoate permease PcaK was shown to modulate the chemotactic resp

236 own that the parasite plasma membrane purine permease, PfNT1, plays an essential function in the tran

237 Here, we describe an intracellular permease, PfNT2.

238 of sucrose permease (CscB) and phenylalanine permease (PheP) as a function of membrane lipid composit

239 ine transport system involving the polyamine permeases PotH and PotI, and was reversible.

240 s, extracellular solute binding proteins and permeases predicted to be active on milk oligosaccharide

241 an alternative hexose transporter, the LmGT4 permease (previously called the D2 permease), on a circu

242 for vaccine antigens identified oligopeptide permease protein A (OppA), an oligopeptide binding prote

243 e triple co-silencing of SlVRSLip, LeHT1 and Permease provoked an immediate cessation of growth of R

244 Additional copies of the pea amino acid permease PsAAP1 were introduced into the pea genome and

245 Furthermore, the permeases PurP and YjcD were subjected to site-directed

246 grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activi

247 shift mutation in the gene encoding nitrogen permease regulator-like 3 (NPRL3).

248 CPr14 shows decreased activity with most PTS permeases relative to HPr, but increases activity with t

249 Can1p, the plasma membrane basic amino acid permease, results in increased cell volume and a severe

250 Ammonium transporter/methylamine permease/rhesus (AMT/Mep/Rh) transporters are responsibl

251 ort elicited endocytosis of other amino acid permeases similarly involves unmasking of a cytosolic Ar

252 libiose permease (MelB) is one among several permeases subject to IIA(Glc) regulation.

253 ability, as did deletion of the oligopeptide permease subunit oppD, suggesting that XIP is imported.

254 es diversion of the high affinity tryptophan permease Tat2 to the vacuole rather than the plasma memb

255 P-binding protein (TDE0143), a transmembrane permease (TDE0144), and a cytosolic ATPase (TDE0145).

256 ABC) transporter, with TGD1 representing the permease, TGD2 the substrate binding protein, and TGD3 t

257 We propose that ArsJ is an efflux permease that extrudes 1As3PGA from cells, where it rapi

258 he opp operon, which encodes an oligopeptide permease that is essential for sporulation and genetic c

259 The genes bbb22 and bbb23 encode purine permeases that are essential for B. burgdorferi mouse in

260 lated proteins are conserved, membrane-bound permeases that bind and translocate heme in metazoan cel

261 silicification includes a family of membrane permeases that recognize and actively transport the solu

262 ained mutant of the Escherichia coli lactose permease (the LacY double-Trp mutant Gly-46-->Trp/Gly-26

263 sylase activity or from defects in AmpG, the permease through which PG monomers enter the cytoplasm f

264 acids and activate expression of amino acid permeases through the SPS-sensing pathway, which consist

265 RNA-binding protein CsrA and the tryptophan permease TnaB coregulate tryptophanase activity, through

266 genes for trytophanase (tnaA), a tryptophan permease (tnaB), and a nitrate reductase (narG), as well

267 nutrients induce endocytosis of the cognate permeases to prevent toxic accumulation of metabolites.

268 HPr functions in concert with particular PTS permeases to prioritize carbohydrate utilization by modu

269 quires the coordinated actions of HRG-1 heme permeases to transport environmental heme into the intes

270 sine uptake by the wild-type and mutant Can1 permeases, together with docking calculations for each a

271 s (HOM3, HOM2, HOM6, THR1, THR4), amino acid permease trafficking (LST4, LST7), and threonine catabol

272 Moreover, the nascent full-length metal permease-transcriptional repressor protein was processed

273 s of the sterol sensing domain (SSD) and the permease transporter domain GxxxD/E motif reveal that th

274 (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including

275 red gene expression, degradation of nutrient permeases, trehalose accumulation, and translation initi

276 B, oppC, oppD, oppF, and oppA), encoding two permeases, two ATPases, and a substrate binding protein.

277 and a specific porin (OphP) in addition to a permease-type phthalate transporter (OphD).

278 t of nodules requires the function of ureide permeases (UPS1) located in cells adjacent to the vascul

279 hia coli mutant lacking the bacterial uracil permease uraA allowed a detailed biochemical characteriz

280 hia coli has 10 members, of which the uracil permease UraA and the xanthine permeases XanQ and XanP a

281 on the recently described x-ray structure of permease UraA.

282 Disruption of ampG (peptidoglycan permease), waaL (lipopolysaccharide O antigen ligase), o

283 targeting of LmxGT1, and trafficking of the permease was arrested in the flagellar pocket.

284 mammalian macrophages, the function of this permease was examined under acidic pH conditions.

285 ion of SlVRSLip and LeHT1; expression of the Permease was not affected by silencing SlVRSLip or LeHT1

286 Expression of the NT3 permease was profoundly downregulated at the protein but

287 by ScoC and encodes a putative oligopeptide permease, was activated indirectly by CodY due to CodY-m

288 to known Saccharomyces cerevisiae polyamine permeases, we identified six C. albicans Dur polyamine t

289 e membrane, and V320N (TM10) inactivates the permease, whereas R327G (TM10) or S426N (TM14) reduces t

290 GAP1 encodes the general amino acid permease, which transports amino acids across the plasma

291 of protonated ammonium outward via the UreI permease, which was shown to facilitate diffusion of bot

292 ichoic acid protein A), a predicted membrane permease whose structural gene is located in an operon w

293 By monitoring fluorescently labeled lactose permease with single-molecule sensitivity, we investigat

294 ransport dynamics is determined by glutamine permeases with two different kinds of kinetics.

295 family transporters and other Na(+)-coupled permeases within MFS has been lacking, although a wealth

296 t from our previous Cys-scanning analysis of permease XanQ, we subjected YgfU to rationally designed

297 ch the uracil permease UraA and the xanthine permeases XanQ and XanP are functionally known.

298 ure experiments, a xanthine/uracil/vitamin C permease (XUV) was upregulated approximately 20-fold und

299 lved crystallographic models of the D-xylose permease XylE from Escherichia coli and GlcP from Staphy

300 utants in the yclNOPQ transporter, including permease YclN, ATPase YclP, and a substrate-binding prot