ライフサイエンスコーパス: permissive

1 s certain other mammalian cells remain fully permissive.

2 , and low concentrations of sialic acid were permissive.

3 human cancer cells (HeLa and A549), one semi-permissive (786-0), and one nonpermissive cell line (PAN

4 icity involves a mechanism that requires the permissive activity of mTORC1 and GSK3beta, demonstratin

5 ve classically activated phenotype to a more permissive alternatively activated phenotype.

6 of hematopoietic origin were generally less permissive and formed discrete groups on the basis of hi

7 nes-suggesting that zebrafish M1-4 is growth permissive and less inhibitory than rat M1-4.

8 and promotes viral propagation in hosts both permissive and non-permissive for AcMNPV and SeMNPV.

9 I at these Bdnf promoters in VTA and altered permissive and repressive histone modifications and occu

10 Permissive and restrictive epistatic mutations across th

11 f the variants in rhesus macaques expressing permissive and restrictive TRIM5alpha alleles.

12 tigate the pathogenesis of adenoviruses in a permissive animal model.

13 strictive animals, but not in the TRIM5alpha-permissive animals, the number of challenges to infectio

14 d different ligands, DMF5 uses a more rigid, permissive architecture with greater reliance on slower

15 l isolates and laboratory HCMV strains, HCMV-permissive astrocytoma, or dendritic cells, as well as "

16 newal versus amniogenesis under self-renewal-permissive biochemical conditions.

17 system (VirB T4SS) to generate a replication-permissive Brucella-containing vacuole (rBCV) derived fr

18 3Dmol.js is distributed under the permissive BSD open source license.

19 Notch is permissive but not instructive for differentiation of mu

20 ation and/or required metabolic functions of permissive cancer cells.

21 % of surveyed individuals are homozygous for permissive CD4 alleles, which encode an asparagine at po

22 Here, we report that HIV-1-permissive CD4 T cells engineered with GPI-scFv X5 are r

23 In line with this, a highly HBV permissive cell clone of HepAD38 cells showed a prominen

24 The second is the nature of the permissive cell functions required by the nonpermissive

25 icroenvironment is converted into a lymphoma-permissive cell niche remain poorly understood.

26 sive human cell culture models and protected permissive cells against HSV-1 infection.

27 rmissive cells, and ICAM-5 expression in non-permissive cells allowed EV-D68 replication.

28 predominant APOBEC3G signature in partially permissive cells but was not mutated in permissive cells

29 We demonstrate that replication in permissive cells in a susceptible host animal is a major

30 ally permissive cells but was not mutated in permissive cells or in nonpermissive cells that block se

31 5 silencing attenuated EV-D68 replication in permissive cells, and ICAM-5 expression in non-permissiv

32 s interaction is required for SVV binding to permissive cells, and that ANTXR1 expression is necessar

33 Using prion permissive cells, we determined how impairment of endocy

34 focusing on engineering HIV-1 resistance in permissive cells.

35 with the more traditionally used replication-permissive cells.

36 rived function, but not all require the same permissive changes that occurred during history.

37 f NKX2-1 and LHX6 promotes transcriptionally permissive chromatin and activates genes expressed in co

38 P cells, indicative of fate restriction, but permissive chromatin at both pro-memory and pro-effector

39 g mechanisms and incompletely characterized, permissive chromatin conditions.

40 EBF1, and IRF4 but is required for a highly permissive chromatin environment, a function that cannot

41 ent non-coding transcription can establish a permissive chromatin environment.

42 erleukin 3 regulated (NFIL3), which promotes permissive chromatin remodelling of the Tim-3 locus and

43 onversely, NKX2-1 is required to establish a permissive chromatin state and transcriptional activatio

44 explained by their transcriptionally poised, permissive chromatin state prior to stimulation.

45 27 (H3K27me3) to establish transcriptionally permissive chromatin.

46 al cells is sufficient to establish a tumour-permissive, chronic inflammatory microenvironment that c

47 to retroviral restriction in relatively non-permissive CNS cell types.

48 nly the conserved N-terminal region but also permissive communication of the Orai N terminus and loop

49 regions were found exclusively in the active/permissive compartment of the nucleus and were predomina

50 substrates that mediate aging as a uniquely permissive condition and the primary risk for neurodegen

51 roinflammatory conditions might constitute a permissive condition for the onset of insulin resistance

52 n, vascular injury, and/or rejection creates permissive conditions for the expression of cryptic auto

53 AQP1 is a water channel, and under permissive conditions, a nonselective cation channel gat

54 veillance and for metastatic outgrowth under permissive conditions.

55 adually becomes highly stable even under non-permissive conditions.

56 on a leash long enough to adopt a triggering-permissive conformation but short enough to limit roamin

57 ormation of mitofusin and promote the fusion-permissive conformation, reversing mitochondrial abnorma

58 e in intracellular calcium levels, under the permissive control of transient receptor potential vanil

59 Membrane-bound Klotho acts as a permissive coreceptor for FGF23, and its expression was

60 zation, and the development of versatile and permissive culture systems.

61 Overuse may lead to permissive decision making favoring intervention.

62 encountering a Tus-ter complex from the non-permissive direction.

63 We found that the permissive effect of large electrolytic DMH lesions on c

64 t memory T cells arise from a subset of fate-permissive effector T cells.

65 ds to increased expression of hCYP11B2, with permissive effects on blood pressure and inflammatory mi

66 solated helicase was also blocked at the non-permissive end, but unexpectedly the isolated polymerase

67 Instead, the polymerase was blocked at the permissive end.

68 We train our deep learning model on permissive enhancers and then adopt a transfer learning

69 Leukemic cells can remodel the niche into a permissive environment favoring leukemic stem cell expan

70 aired with age, which, we propose, creates a permissive environment for protein aggregation, unresolv

71 oward a proregenerative population creates a permissive environment for repair.

72 es the balance of growth factors, creating a permissive environment for repair.

73 ssue damage during early life creates a more permissive environment for the production of LTP within

74 /PLK-1 in the posterior cytoplasm provides a permissive environment for the retention of POS-1, which

75 ulatory mechanisms create an immunologically permissive environment for tumor colonization.

76 extracellular matrix remodelling to create a permissive environment for tumour cell invasion and prom

77 e IFN produced a weaker response in the more permissive environment of the macrophage.

78 nervous system is limited in part by the non-permissive environment, including axonal growth inhibito

79 ruct MSC toward the creation of regeneration-permissive environment.

80 t be useful to enable axon regrowth in a non-permissive environment.SIGNIFICANCE STATEMENT Repair of

81 ults can induce overly restrictive or overly permissive epigenetic landscapes that contribute to path

82 nscription was associated with enrichment of permissive epigenetic marks on histone proteins in the h

83 deed, Batf(-/-) CD4(+) T cells do not obtain permissive epigenetic modifications within the Th2 locus

84 -length L1s located within transcriptionally permissive euchromatic environments, and promote deposit

85 site genome is packaged as transcriptionally permissive euchromatin with few loci embedded in silence

86 methylation programming, thereby providing a permissive expression environment for newly formed/trans

87 udies identify brain insulin as an important permissive factor in hepatic VLDL secretion that protect

88 vealed upregulation of chemokines and axonal permissive factors including FGF2, BDNF, and NGF.

89 oung children to produce conditions that are permissive for accumulation of multiple driver mutations

90 propagation in hosts both permissive and non-permissive for AcMNPV and SeMNPV.

91 Induction of a chromatin environment permissive for acquiring neuronal subtype identity is th

92 DBA/2 mice were permissive for all 4 HMPV subgroups, and 54G10 was effec

93 pressive extracellular matrix to become more permissive for axon regrowth.

94 ic rearrangements leading to genetic changes permissive for cancer initiation and progression.

95 ither certain biochemical systems are simply permissive for cellular oscillations (with frequencies f

96 We show that RA is permissive for cerebrovascular growth via suppression of

97 d constrain the substrate sequences that are permissive for cleavage of one type 2 transmembrane segm

98 , which provides selective microenvironments permissive for DC development.

99 Thus, X is broadly permissive for dosage compensation, and the DCC acts via

100 ly demethylated EBV type III latency program permissive for expression of EBNA2, EBNA3s, and LMP tran

101 abilizing the SC and making chromosomes less permissive for further DSB formation.

102 These results reveal that acetylation is permissive for generation of the apoptotic form of FOXO3

103 maturation with a prolonged critical period permissive for giant depolarizing potentials.

104 ar purines that are either permissive or non-permissive for growth and monitoring for previously defi

105 Studies have shown that NPCs are fully permissive for HCMV infection, which causes neural cell

106 cells in this stage were substantially more permissive for HIV-1 latent infection than other CD4(+)

107 Myeloid cells are permissive for HIV/SIV replication in vitro and may cont

108 PV16) gene expression, cervical cancer cells permissive for HPV16 late gene expression were identifie

109 However, LAD2 MCs were permissive for HRV replication and release of infectious

110 h, inhibits the endothelial programme and is permissive for HSC specification.

111 suggest that these gallinaceous poultry are permissive for infection and sustainable transmissibilit

112 RIM5alpha) genotypes that are restrictive or permissive for infection by the challenge virus SIVsmE66

113 R) in order to create a cellular environment permissive for infection.

114 f the bacteria, the range of host cell types permissive for initiation and completion of the intracel

115 loading of modified mRNAs renders them more permissive for initiation by favoring either ribosome re

116 te immune functions to create an environment permissive for its intracellular survival and growth.

117 A astroglial cell-derived cells to be highly permissive for JUNV infection and generated new cell lin

118 a platform on the alpha1 helix that is less permissive for KIR3DL1 binding.

119 genitors and CD14+ monocytes are usually non-permissive for lytic gene expression which can lead to t

120 promotes viral reactivation or renders them permissive for lytic infection.

121 e early endosome compartment to make it more permissive for membrane fusion of early-penetrating viru

122 pothesized that the Msp2 HVR is structurally permissive for mosaic expression.

123 P1 to Mtb-associated structures and are more permissive for Mtb growth.

124 cular component of the "field change" milieu permissive for neoplastic colon growth.

125 tion that maintains the extracellular milieu permissive for neuronal activity.

126 do we understand to what extent the cell is permissive for new protein associations - a key requirem

127 yonic-derived, MR(hi) dermal macrophages are permissive for parasite growth even in a strong Th1-immu

128 We demonstrated that anti-CD20 alone is permissive for Pneumocystis infection and that anti-CD20

129 ary cultures upregulated the number of cells permissive for primary lytic KSHV infection.

130 perone overexpression lowers the temperature permissive for proliferation of cells expressing a G int

131 ovo screening of athletes, which may be cost permissive for some sporting organizations.

132 ways or in stress response pathways that are permissive for strong oncogenic signaling.

133 , yielding events that would not normally be permissive for survival during thymic development.

134 rbor of CA1 neurons that renders those cells permissive for the efficient generation of synaptic inpu

135 ioning (EMT) CD4(+) T cells are particularly permissive for the establishment of latent HIV-1 infecti

136 Thus, MYXV is fully or partially permissive for the majority of human cancer cells that h

137 w that D2R signaling in MSNs is required and permissive for the motor stimulant effects of cocaine an

138 MCs are permissive for the replication and release of HRV, which

139 Syrian hamsters are permissive for the replication of species C human adenov

140 d incisions on opposite DNA strands that are permissive for TNR expansion.

141 dCas9 binding creates an environment that is permissive for transcription initiation/termination, thu

142 longation which dictates whether the gene is permissive for transcription.

143 ounding transformed foci became increasingly permissive for transformation with serial culture.

144 to prevent initiation of genome instability permissive for tumorigenesis.

145 rated that neurons are nearly 100 times more permissive for WT VZV infection than very-early-passage

146 nd cell subsets not previously recognized as permissive for YFV replication, and we highlight potenti

147 Consistent with their being permissive for ZIKV infection, primary trophoblasts expr

148 docytes, renal GECs, and mesangial cells are permissive for ZIKV infection.

149 This permissive form of experience-dependent plasticity enabl

150 In the comparable TRIM5alpha-permissive group, only 1 of 12 animals resisted all 12 c

151 When shifted to a semi-permissive growth temperature, the neo1-1(ts) mutant bec

152 nts display a loss of PS and PE asymmetry at permissive growth temperatures as measured by hypersensi

153 ) in both primary and growing oocytes, while permissive H3K36me3 increases specifically at these CGIs

154 in HAdV-C5-infected ones because more of the permissive hepatocytes get infected.

155 lyzed for HBV and HDV receptor activity in a permissive hepatoma cell line.

156 anism for the formation of transcriptionally permissive heterochromatin that is compatible with its b

157 icts a largely unfettered expansion within a permissive host and geographic population with little ev

158 Coxiella burnetii replicates within permissive host cells by employing a Dot/Icm type IV sec

159 tal virus, being able to infect not only the permissive hosts of its parental viruses but also a nonp

160 g the 58 human DEAD-box RNA helicases in two permissive human cancer cells (HeLa and A549), one semi-

161 gene profoundly reduced HSV-1 infectivity in permissive human cell culture models and protected permi

162 strate that impaired SOCS3 feedback leads to permissive IL10/STAT3 signalling that promotes alternati

163 r injury, we found that these enhancers were permissive in early development prior to Pmp22 upregulat

164 ino acid IL3 deleted isoform hH3R365 is more permissive in its signaling than hH3R445: 2-(1H-imidazol

165 we find that YTHDF2 deficiency is partially permissive in mice and results in female-specific infert

166 een difficult to test owing to the lack of a permissive in vivo model of HAdV infection.

167 ene lists frequently are not curated or have permissive inclusion criteria, impairing their use.

168 Fully permissive infection was common in cancer-derived cell l

169 essive heterochromatin environment to a more permissive interior chromatin environment.

170 hA2 receptor was critical for establishing a permissive intracellular replication compartment, the pa

171 l plane, but whether Wnts are instructive or permissive is debated.

172 insensitive HK1.ras(1276) mice, suggesting a permissive K14.ROCK(er)/HK1.ras(1205) papilloma context

173 Permissive labelling could be incorporated onto these pr

174 ing prohibition for a less punitive and more permissive legal stance on cannabis, such as decriminali

175 interactions with CD1c carrying foreign Ags, permissive ligands, and nonpermissive lipid ligands clar

176 Over a broad range of permissive lipid compositions, the Arg-325 variant consi

177 ereas high viral titers could be obtained at permissive low temperatures (33 degrees C).

178 Thus LPS stimulated monocytes are partially permissive lytic gene expression but did not have long t

179 raffics to the cytoplasm of cells undergoing permissive lytic infections and latently infected cells

180 num) PGL promotes bacterial spread to growth-permissive macrophages, while M. leprae PGL-1 induces ma

181 ages by acting either in an instructive or a permissive manner.

182 FL and IL-7 regulate B-cell commitment in a permissive manner: FL by inducing proliferation of Ly6D(

183 children from families with higher levels of permissive (mean CAFAS of 49.71, 35.74, 58.14, and 16.16

184 ncy of pre-tumor lesions and creates a tumor-permissive microenvironment at the earliest, preneoplast

185 en tumor cells and stromal cells to create a permissive microenvironment for tumor growth and metasta

186 eplication of adult mouse beta-cells given a permissive microenvironment.

187 upplies proinflammatory cytokines favoring a permissive milieu for cancer cell growth and invasive be

188 om murine ischemic muscles, thus providing a permissive milieu to transplanted LEP-expressing APCs.

189 s of HLA-DP as model antigens for clinically permissive mismatches mediating limited T-cell alloreact

190 These results suggest a supportive versus permissive model, where patterns of coordinated activity

191 dopt either a fusion-constrained or a fusion-permissive molecular conformation, directed by specific

192 lly infected resident macrophage into growth-permissive monocytes.

193 nse of infected keratinocytes attracts virus-permissive myeloid cells that inadvertently spread DENV

194 encouraging the entry and infection of virus-permissive myeloid cells.

195 transmitted to epithelial cells, the highly permissive nature of this cell type for lytic replicatio

196 the absence of molecular cues, structurally permissive neuronal somata and dendrites remain unmyelin

197 s and abolished virus neurotropism in highly permissive newborn mice.

198 modulate diverse host processes to create a permissive niche for its replication in phagocytes.

199 ellular signaling to establish a replication-permissive niche, the Legionella-containing vacuole (LCV

200 ggest that the T7 replisome is fundamentally permissive of DNA lesions via pathways that do not requi

201 ely because of the presence of histone marks permissive of gene activation.

202 inations of KIR3DL1 and HLA ligands are more permissive of mAb-mediated antitumor effect.

203 transient dysfunction of CD8(+) dT that are permissive of placental and fetal development, and rever

204 ry in the unphosphorylated state and becomes permissive of potentiation upon phosphorylation.

205 f p65 and of methylation of histone residues permissive of transcription.

206 olic homeostasis is consistent with it being permissive of, and essential to, development of higher p

207 positive and negative selections, which are permissive only for immature thymocytes with intermediat

208 ges (SSMs) exposed to lymph-borne HSV-1 were permissive only when type I interferon (IFN-I) signaling

209 from an inhibitory closed conformation to a permissive open conformation, speeding up actin polymeri

210 By contrast, permissive or "plastic" states may allow stochastic onco

211 els of extracellular purines that are either permissive or non-permissive for growth and monitoring f

212 suggests that follicle depletion provides a permissive ovarian environment for oncogenic transformat

213 show that reduced KC Par3 function fosters a permissive P-cadherin-dependent niche for MC transformat

214 rd a more elongated conformation at a fusion permissive pH.

215 2 regulation, partially explaining the tumor-permissive phenotype of mice lacking Sirt2 Cancer Res; 7

216 HCV needs to stimulate PI4KA to create a permissive phosphatidylinositol 4-phosphate-enriched mem

217 op a genome-wide method, PROPER, that uses a permissive PSI-BLAST approach to predict promiscuous act

218 likely to be a key step in establishing the permissive replication compartment.

219 ell destruction, thereby serving as a likely permissive reservoir and portal of fetal transmission wi

220 h signaling, suggesting that Intu performs a permissive role during BCC formation.

221 Defective immune regulation plays a permissive role enabling effector cells to initiate and

222 These results are more consistent with a permissive role for experience in the development of dir

223 levels above a critical threshold playing a permissive role in expression of an underlying infradian

224 ng that PKC-mediated phosphorylation plays a permissive role in purinoceptor-stimulated BK activation

225 phages, the prostanoid EP1 receptor played a permissive role in suppressing neovascularization and in

226 as the anterior cingulate appeared to play a permissive role in this form of reversal learning.

227 Our results suggest a permissive role of combined thyroid and glucocorticoid h

228 These findings identify DSCAM as a permissive signal that promotes the growth and fascicula

229 the surface of epidermal cells act as local permissive signals for the dendritic growth and maintena

230 from patients with pre-B ALL restored a non-permissive state and induced energy crisis and cell deat

231 to how MyoD blocks proliferation to create a permissive state for differentiation.

232 dynamics arise from alternating inactive and permissive states.

233 neration against high load requires a second permissive step linked to a change in the structure of t

234 studies on other proteins, which had a more permissive sterol dependence.

235 oligodendrocytes are capable of myelinating permissive structures in the absence of molecular cues,

236 These alternatives all require prior permissive substitutions that do not enhance the derived

237 ronically contused spinal cord can provide a permissive substrate for the regeneration of certain neu

238 ist E11 infection, enteroendocrine cells are permissive, suggesting that enteroviruses infect specifi

239 otein (GFP)-specific antibodies than RD in a permissive Syrian hamster model.

240 Knockdown of Tyk2 at the permissive temperature (active v-Src) in LA-25 cells dec

241 ctive in actomyosin ring assembly at the non-permissive temperature [6, 7].

242 work [3] was performed at 25 degrees C, the permissive temperature for myo2-E1, we compared cytokine

243 ty in both resistant cell lines grown at the permissive temperature of 32.5 degrees C.

244 tionally, growth of patient fibroblasts at a permissive temperature or with chemical chaperones incre

245 At the permissive temperature, the Tor2 mutant protein is parti

246 in ring contraction when rings isolated from permissive temperature-grown cells are incubated with AT

247 e into Atp8p at nonpermissive but not at the permissive temperature.

248 ome lethal in the presence of the drug under permissive temperature.

249 eadthrough was observed in the mutant at the permissive temperature.

250 eloped as normal fertile XX and XY adults at permissive temperatures below 20 degrees C, but at highe

251 Among the predicted readthrough-permissive TGA variants, only 2 (p.W240X and p.R384X) re

252 ion, however, GC TFH were substantially more permissive than CXCR5(+)PD-1(low) or EF cells, suggestin

253 We find that TFR cells are more permissive than TFH cells to R5-tropic HIV-1 ex vivo TFR

254 he low-expressing B21 haplotype is even more permissive than the promiscuous binding shown by the dom

255 on of the entire E2F family in Drosophila is permissive throughout most of animal development until p

256 As natural vectors, mosquitoes are very permissive to and allow systemic and persistent arboviru

257 nd GBP3 expression and these cells were more permissive to Brucella replication compared with wild-ty

258 regulatory programs within the lung that are permissive to cancer metastasis.

259 osomes assembled on native DNA sequences are permissive to Cas9 action.

260 st survival and reveals others that are more permissive to change-containing variation acquired from

261 which demonstrated that early HSC pools were permissive to clonal evolution driven by drift.

262 The C-terminal domain is permissive to cytoplasmic shuttling and interacts with r

263 p90alpha secretion from the tumour cells was permissive to cytotoxicity by hypoxia, whereas supplemen

264 caught Ae. aegypti, render the mosquito more permissive to DENV infection.

265 icroenvironments in distant tissues that are permissive to disseminated tumor cells.

266 reased the proportion of the cell population permissive to EAV infection from <3% to almost 100%.

267 ever, these changes render the IL-2 promoter permissive to Foxp3-induced transcriptional repression.

268 hepatocytes in vivo renders rhesus macaques permissive to HBV infection.

269 Here, we show that TFR cells are highly permissive to HIV-1 both ex vivo and in vivo The express

270 tudies that showed that TFH cells are highly permissive to HIV-1 included TFR cells in their definiti

271 ls expressed CCR5 and CXCR3 and are the most permissive to HIV-1 infection.

272 Thus, GC TFH are highly permissive to HIV-1, but downregulate PD-1 and, to a les

273 ells have previously been shown to be highly permissive to HIV-1.

274 (TFH) within germinal centers (GC) is highly permissive to HIV-1.

275 set, which consists of cells that are highly permissive to HIV-1.

276 7/9(-/-), and Unc93b1(-/-) cells were highly permissive to L. major replication.

277 and rostral migratory stream (RMS), yet are permissive to large-scale neuroblast migration.

278 rmiformis and Dictyostellium discoideum) are permissive to M. bovis infection and that the M. bovis b

279 ated disruption of Nrp1/VEGF-A signalling is permissive to maturation and maintenance of the vasculat

280 nes coding for structural proteins were more permissive to mutations.

281 es from subjects with SC infection were less permissive to parasite penetration and had a greater abi

282 d larvae develop into adults that are highly permissive to parasites and survive longer after infecti

283 rosslinker (KKCGGPQG downward arrowIWGQGCKK) permissive to proteolytic remodeling and the adhesive CR

284 ntrinsically fluorescent protein fibrils are permissive to proton transfer across hydrogen bonds whic

285 e data demonstrate that TFR cells are highly permissive to R5-tropic HIV-1 both ex vivo and in vivo T

286 Whether T cells are permissive to RSV infection is unknown.

287 or its nucleotide exchange factor BLOC-3 are permissive to S. Typhi infection and exhibit increased s

288 Partial disruption of the patch, while permissive to the recognition of CD1d, significantly alt

289 Thus, CORT is permissive to trauma-induced changes in BLA function.

290 Therefore, defining which WBCs are permissive to Zika virus (ZIKV) is critical.

291 to show that placental macrophages are more permissive to ZIKV infection than trophoblasts, which ma

292 ation, nor did they lead to progeny virus in permissive, transfected human Huh7.5 hepatoma cells upon

293 genotypes as efficiently as in macaques with permissive TRIM5alpha genotypes.

294 The association of permissive underfeeding versus standard feeding and 90-d

295 This is a post hoc analysis of the PermiT (Permissive Underfeeding versus Target Enteral Feeding in

296 To examine the effect of permissive underfeeding with full protein intake compare

297 patients with high and low nutritional risk, permissive underfeeding with full protein intake was ass

298 ndard-feeding group died (relative risk with permissive underfeeding, 0.94; 95% confidence interval [

299 similar: 121 of 445 patients (27.2%) in the permissive-underfeeding group and 127 of 440 patients (2

300 During the intervention period, the permissive-underfeeding group received fewer mean (+/-SD