ライフサイエンスコーパス: permissive

1 tion of feline and human cDNAs rendered them permissive.

2 cells to be susceptible to infection but not permissive.

3 ediate the actions of ketamine but rather is permissive.

4 he transcription factor DUX4; coupled with a permissive 4qA haplotype supplying a poly(A) signal.

5 human cancer cells (HeLa and A549), one semi-permissive (786-0), and one nonpermissive cell line (PAN

6 The permissive activity of butyrate was mediated by GPR43 si

7 icity involves a mechanism that requires the permissive activity of mTORC1 and GSK3beta, demonstratin

8 ervention merely modulates the behaviourally permissive activity window in which the circuit operates

9 Our data suggest that a permissive AEA tone within the BLA might gate GABA relea

10 e as a living, smart material that creates a permissive, all-in-one niche which provides neurotrophic

11 tion between adrenal restrictive and adrenal permissive alleles and FEV(1)PP in patients with (GC) an

12 Sox9(EGFP) populations, we classify broadly permissive and dynamic chromatin relative to TF usage.

13 fferences in the activity of the UPR between permissive and elevated temperature in conjunction with

14 nes-suggesting that zebrafish M1-4 is growth permissive and less inhibitory than rat M1-4.

15 efficiency-of-plating analysis performed at permissive and nonpermissive temperatures revealed that

16 states that cycle between transcriptionally permissive and nonpermissive.

17 Here, we evaluate infection of highly permissive and poorly permissive cancer cells with wild-

18 compartment is filled with cells of maximal permissive antigen reactivity.

19 We then identified permissive architectures for minimal synthetic plant pro

20 central peptide feature, although were more permissive at peripheral peptide positions and, accordin

21 newal versus amniogenesis under self-renewal-permissive biochemical conditions.

22 oss-flow-in a thin, flat channel with a semi-permissive bottom wall membrane.

23 system (VirB T4SS) to generate a replication-permissive Brucella-containing vacuole (rBCV) derived fr

24 Notch is permissive but not instructive for differentiation of mu

25 ng cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE

26 te infection of highly permissive and poorly permissive cancer cells with wild-type adenoviruses and

27 were reported for 79 patients (6.2%) in the permissive care group and 75 patients (5.8%) in the usua

28 cell (hMSCs) was used as a viral replication-permissive carrier for oAd with an aim to improve the sy

29 changes in IFN-gamma-mediated recruitment of permissive CCR2(+) monocytes.

30 In line with this, a highly HBV permissive cell clone of HepAD38 cells showed a prominen

31 ve demonstrated that even in susceptible and permissive cell populations, abortive infections can be

32 enteroendocrine cells (EECs) identified as a permissive cell type in this patient.

33 gH is critical for KSHV infection of highly permissive cell types, including epithelial, endothelial

34 blish infection in hosts by targeting highly permissive cell types.

35 essential role in viral infection of diverse permissive cell types.

36 receptor (Igf1r) in mouse embryos creates a permissive "cell-competitive niche" in several organs, s

37 CDKN2C is overexpressed in highly permissive cells and HBV-infected patients.

38 ondingly, I/LnJ CD300LF bound MNV virions in permissive cells but not in nonpermissive cells.

39 We demonstrate that replication in permissive cells in a susceptible host animal is a major

40 karyon cells generated by fusion of HeLa and permissive cells supported H1N1 virus growth, suggesting

41 s interaction is required for SVV binding to permissive cells, and that ANTXR1 expression is necessar

42 Using prion permissive cells, we determined how impairment of endocy

43 ould not be amplified through coculture with permissive cells.

44 icted committed B-progenitor might provide a permissive cellular context for prenatal B-progenitor le

45 rived function, but not all require the same permissive changes that occurred during history.

46 This erythroid-permissive chromatin conformation is retained in bilinea

47 suggests enrichment of the transcriptionally permissive chromatin mark H3K4me3 (trimethylation of lys

48 ticity is thought to be regulated by broadly permissive chromatin shared between ISCs and their proge

49 required for progenitor phenotypes were in a permissive chromatin state and unmethylated in RPE.

50 Arid1a establishes a permissive chromatin state at LPLC-enriched genes during

51 ters for photoreceptor genes were found in a permissive chromatin state, but were highly-methylated.

52 Once a permissive chromatin structure has assembled, transgene

53 Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription sta

54 on occurs during the S-phase of increasingly permissive cleavage cycles.

55 nly the conserved N-terminal region but also permissive communication of the Orai N terminus and loop

56 lammatory genes toward the transcriptionally permissive compartment.

57 n, vascular injury, and/or rejection creates permissive conditions for the expression of cryptic auto

58 Although experiments were performed under permissive conditions, mTPP provided insights into the u

59 that anterograde transport at 32 degrees C, permissive conditions, through the Golgi apparatus was l

60 nse but is still capable of generating DC in permissive conditions.

61 adually becomes highly stable even under non-permissive conditions.

62 mitment in pluripotent cells, even under non-permissive conditions.

63 t stabilize the ligand-binding pocket in its permissive conformation, and how many permissive conform

64 and-channel interactions that stabilize this permissive conformation.

65 in its permissive conformation, and how many permissive conformations the ligand-binding pocket may a

66 he ligand-binding pocket in nearly identical permissive conformations; functionally, they all yielded

67 for these phages and that expression of non-permissive CPS variants is selected under phage predatio

68 velop metastasis, indicating the presence of permissive cues for distant spread.

69 zation, and the development of versatile and permissive culture systems.

70 Using permissive cutoffs, modified reference genomes are found

71 We found that the permissive effect of large electrolytic DMH lesions on c

72 This permissive/enabling function of neuromodulators has been

73 id lineage on the creation of a regeneration-permissive environment and could be further exploited to

74 genetic mutations that are deleterious in a permissive environment but beneficial in a specific envi

75 ings indicate that alpha-synuclein creates a permissive environment for aggregate persistence by inhi

76 ntains chronic inflammation, which creates a permissive environment for cancer development.

77 ignaling to resolve inflammation, creating a permissive environment for oligodendrocyte differentiati

78 bacilli is the sole mechanism that creates a permissive environment for pathogens during vaginal dysb

79 es the balance of growth factors, creating a permissive environment for repair.

80 Pathogens usurp host pathways to generate a permissive environment for their propagation.

81 trinsic defenses, and thereby provide a more permissive environment for virus replication.

82 help create and maintain an immunologically permissive environment.

83 al colonization tracked spatial expansion of permissive environments, with a temporal lag.

84 The high entropy of GSCs is driven by a permissive epigenetic landscape and a mutational landsca

85 epigenetic priming factors that establish a permissive epigenetic landscape at a subset of developme

86 ults can induce overly restrictive or overly permissive epigenetic landscapes that contribute to path

87 We show that permissive epigenetic regulation of cldn5 expression and

88 that formative TF target genes are marked by permissive epigenomic signatures in the naive state, ind

89 -length L1s located within transcriptionally permissive euchromatic environments, and promote deposit

90 site genome is packaged as transcriptionally permissive euchromatin with few loci embedded in silence

91 ctional manipulations reveal that there is a permissive excitability window for granule cells that is

92 is by releasing mycobacteria into the growth-permissive extracellular environment.

93 includes neuroinflammatory signaling and non-permissive extracellular matrix (ECM) components.

94 vealed upregulation of chemokines and axonal permissive factors including FGF2, BDNF, and NGF.

95 at endosomal membrane curvature is not a key permissive feature for viral entry, at least lipid mixin

96 13 viral proteins during infection of highly permissive fibroblasts.

97 Induction of a chromatin environment permissive for acquiring neuronal subtype identity is th

98 cells (HSC, LX-2), and hepatocytes (Huh-7), permissive for active replication of HCV and HIV, and as

99 The result is a scenario permissive for aggressive tumorigenesis especially withi

100 This is non-permissive for bacterial proliferation.

101 ic rearrangements leading to genetic changes permissive for cancer initiation and progression.

102 xpress fewer IFN-stimulated genes and become permissive for CHIKV infection.

103 egate formation and captured stable proteins permissive for cross-presentation.

104 , which provides selective microenvironments permissive for DC development.

105 s, and humans (designated as XPSCs) that are permissive for direct PGC-like cell induction in vitro a

106 tract formation and renders the striatum non-permissive for dopaminergic and other forebrain tracts.

107 t's cells carrying SMCHD1 mutations are both permissive for DUX4 expression, a transcription factor w

108 abilizing the SC and making chromosomes less permissive for further DSB formation.

109 rs all neuroblast-derived cells in a lineage permissive for Gal4 activity.

110 These results reveal that acetylation is permissive for generation of the apoptotic form of FOXO3

111 ntiate, which creates an environment that is permissive for hepatic fibrosis; elucidation of these ea

112 cells in this stage were substantially more permissive for HIV-1 latent infection than other CD4(+)

113 However, LAD2 MCs were permissive for HRV replication and release of infectious

114 sis, LSECs undergo capillarization, which is permissive for HSC activation, the proximate event in he

115 show that (i) hiPSC-derived CNS neurons are permissive for HSV-1 infection; (ii) a quiescent state e

116 suggest that these gallinaceous poultry are permissive for infection and sustainable transmissibilit

117 mature DCs (iDCs), mature DCs (mDCs) are not permissive for infection with herpes simplex virus type

118 loading of modified mRNAs renders them more permissive for initiation by favoring either ribosome re

119 a pneumophila creates an intracellular niche permissive for its replication by extensively modulating

120 sm seeks residence in macrophages, which are permissive for its survival.

121 and G(2)/M phases of the host cell cycle are permissive for Legionella pneumophila replication, where

122 Neural progenitor cells are permissive for lytic infection.

123 g secondary colony growth at sites otherwise permissive for metastatic outgrowth.

124 gs suggest that changes in Cdk1 activity are permissive for mitotic entry and exit but that the chang

125 P1 to Mtb-associated structures and are more permissive for Mtb growth.

126 limiting determinant of whether the heart is permissive for Myc transcriptional activation.

127 human intestinal enteroids were shown to be permissive for norovirus infection.

128 ary cultures upregulated the number of cells permissive for primary lytic KSHV infection.

129 uman T-cell line expresses HTLV-1 Tax and is permissive for replication of an HIV-1 gp41 mutant lacki

130 of the replicative DNA polymerases that are permissive for ribonucleotide incorporation, thus genera

131 Several species are permissive for SARS-CoV-2 replication, often exhibiting

132 hat keep the effectors in a structural state permissive for secretion.

133 gnaling kinases in a metastable conformation permissive for signaling activation.

134 ways or in stress response pathways that are permissive for strong oncogenic signaling.

135 udies identify a novel redox pathway that is permissive for T3-mediated cardiomyocyte proliferation-t

136 here CHD4 generates a chromatin architecture permissive for the binding of the tumor driver and fusio

137 ioning (EMT) CD4(+) T cells are particularly permissive for the establishment of latent HIV-1 infecti

138 a chromatin accessibility landscape that was permissive for the expression of development-related gen

139 the limbic system that are both critical and permissive for the expression of motivated behavior and

140 d for short-term applications, which are not permissive for the long-term, longitudinal study of panc

141 Thus, MYXV is fully or partially permissive for the majority of human cancer cells that h

142 ogen signaling that promotes cellular states permissive for the meiotic division phase.

143 y influences insulin sensitivity but also is permissive for the normal CRR to insulin-induced hypogly

144 ycemia in a preclinical starvation model, is permissive for the normal CRR to insulin-induced hypogly

145 dCas9 binding creates an environment that is permissive for transcription initiation/termination, thu

146 to prevent initiation of genome instability permissive for tumorigenesis.

147 rated that neurons are nearly 100 times more permissive for WT VZV infection than very-early-passage

148 nd cell subsets not previously recognized as permissive for YFV replication, and we highlight potenti

149 Consistent with their being permissive for ZIKV infection, primary trophoblasts expr

150 At non-permissive forces for condensation, ParB binds non-speci

151 GA pathway is required to precisely time the permissive gating of GA sensitivity, thereby determining

152 cellular differentiation and correlate with permissive gene expression, phenomena that are linked to

153 and cellular signalling, in the mediation of permissive gene expression.

154 discuss how failures in DNA repair produce a permissive genetic environment in which preneoplastic ce

155 63.4 (P < 0.001), and for homozygous adrenal permissive genotype, it is 66.7 vs. 67.7 (P = 0.92).

156 In patients with the homozygous adrenal permissive genotype, there was no FEV(1)PP difference in

157 E-cadherin supplies a permissive haptotactic cue.

158 in HAdV-C5-infected ones because more of the permissive hepatocytes get infected.

159 -wide gain-of-function screen using a poorly permissive hepatoma cell line to uncover host factors en

160 ts toward opioids promoting higher levels of permissive histone acetylation and lower levels of repre

161 Rsad2 was enriched for STAT1 binding and the permissive histone mark H3K4me3.

162 /Th2 immunity first controls the size of the permissive host cell reservoir.

163 on, we discuss the putative contributions of permissive host environments, transcriptional plasticity

164 llele limits conversion, whereas the adrenal permissive HSD3B1(1245C) allele increases DHEA metabolis

165 g the 58 human DEAD-box RNA helicases in two permissive human cancer cells (HeLa and A549), one semi-

166 they remained far lower than those in highly permissive human hepatoma cells, and minimal infectious

167 At 90 days, 500 of 1221 (41.0%) in the permissive hypotension compared with 544 of 1242 (43.8%)

168 g vasopressors for vasodilatory hypotension, permissive hypotension compared with usual care did not

169 Patients randomized to the permissive hypotension group had lower exposure to vasop

170 rs guided either by MAP target (60-65 mm Hg, permissive hypotension) (n = 1291) or according to usual

171 we find that YTHDF2 deficiency is partially permissive in mice and results in female-specific infert

172 een difficult to test owing to the lack of a permissive in vivo model of HAdV infection.

173 ene lists frequently are not curated or have permissive inclusion criteria, impairing their use.

174 perties in mouse xenografts via generating a permissive inflammatory microenvironment constituted by

175 and capacitated spermatozoa under proteasome permissive/inhibiting conditions were used to isolate pu

176 popliteal lymph node (pLN) to infect highly permissive innate-like B-1 cells and establish infection

177 insensitive HK1.ras(1276) mice, suggesting a permissive K14.ROCK(er)/HK1.ras(1205) papilloma context

178 configuration of stripe domains represents a permissive landscape facilitating both productive and op

179 on in firearm-related deaths relative to the permissive legal regime.

180 llophilic macrophages for trans-infection of permissive lymphocytes.

181 Thus LPS stimulated monocytes are partially permissive lytic gene expression but did not have long t

182 Here, we perform RNAseq on restrictive and permissive macrophages and reveal that the expression of

183 onse properties, followed by a late phase of permissive maturation, when sensory-driven activity mere

184 al stress, rather than mechanical load, as a permissive mechanical parameter that allows for noise-de

185 Our findings reveal a permissive mechanism that bridges WAT inflammation to wh

186 However, their role in the formation of a permissive metastatic niche is unresolved.

187 atients is shown, consistent with postulated permissive microbiome driving CA lesion genesis via lipo

188 re head-dependent extrinsic signals create a permissive microenvironment for stem cell-driven regener

189 eved a durable clinical response displayed a permissive microenvironment, substantiated by the upregu

190 nd RDEB, as well as the formation of a tumor-permissive microenvironment.

191 nd how these may contribute towards a tumour permissive microenvironment; these changes encompass bio

192 upplies proinflammatory cytokines favoring a permissive milieu for cancer cell growth and invasive be

193 es to maintain its health span and provide a permissive milieu for neurogenesis.

194 om murine ischemic muscles, thus providing a permissive milieu to transplanted LEP-expressing APCs.

195 nosuppressive microenvironment into a T cell-permissive milieu.

196 provided as an open source R package under a permissive MIT license and includes detailed user docume

197 n in Python 3 and freely available under the permissive MIT license.

198 lly infected resident macrophage into growth-permissive monocytes.

199 re we show that MV RNA remains detectable in permissive mouse neurons long after challenge with MV an

200 nse of infected keratinocytes attracts virus-permissive myeloid cells that inadvertently spread DENV

201 ough many attempts are made to reconstruct a permissive niche for nerve regeneration, solely using a

202 ial to build an all-in-one, multifunctional, permissive niche for promoting neuronal while inhibiting

203 ely because of the presence of histone marks permissive of gene activation.

204 ted, and imprinted with gut-homing integrins permissive of migration into the damaged GI tract, resul

205 that blocking GM-CSF makes macrophages more permissive of Mtb growth while addition of GM-CSF increa

206 transient dysfunction of CD8(+) dT that are permissive of placental and fetal development, and rever

207 tations are available free of charge under a permissive open source license.

208 OMA standalone is available under the permissive open source Mozilla Public License Version 2.

209 By contrast, permissive or "plastic" states may allow stochastic onco

210 highly-pathogenic AIV may be facilitated by permissive or compensatory mutations occurring across th

211 tin regions (OCRs) can be defined as broadly permissive or dynamic in a locus-specific manner, with d

212 s, it is unclear whether experience exerts a permissive or instructive influence.

213 for PML II degradation was detected in cells permissive or nonpermissive to the ICP0-null virus; (ii)

214 rai subunits as a core element of an opening-permissive Orai channel architecture.

215 show that reduced KC Par3 function fosters a permissive P-cadherin-dependent niche for MC transformat

216 Our investigations into this partially permissive phenotype of the herpesvirus Epstein-Barr vir

217 on in firearm-related deaths relative to the permissive policy regime.

218 apping rate even in the presence of the more permissive PTM H3K36me2.

219 Consistent with a permissive regulatory role, SNr output provides informat

220 d of Rnr1, RER-deficient, and harbor an rNTP-permissive replicative Pol mutant, excessive accumulatio

221 h signaling, suggesting that Intu performs a permissive role during BCC formation.

222 These results are more consistent with a permissive role for experience in the development of dir

223 odifier of Jag1(+/-) liver phenotypes with a permissive role in biliary development.

224 levels above a critical threshold playing a permissive role in expression of an underlying infradian

225 nally control food intake, consistent with a permissive role in feeding.

226 eurons in adult males, where it likely has a permissive role in odr-10 activation.

227 ng that PKC-mediated phosphorylation plays a permissive role in purinoceptor-stimulated BK activation

228 phages, the prostanoid EP1 receptor played a permissive role in suppressing neovascularization and in

229 Our results suggest a permissive role of combined thyroid and glucocorticoid h

230 athways relevant in NSCLC, suggesting that a permissive role of PKCe in KRAS-driven lung tumorigenesi

231 tail GluA1 phosphorylation sites exhibited a permissive role, limiting the extent to which AKAP79 pro

232 HCV replication in non-permissive species may be limited by incompatibilities b

233 nd PP2A-B55 thus create a spindle checkpoint-permissive state and ensure the fidelity of mitosis.

234 urally occurring EC proliferation provides a permissive state for the appearance of these malformatio

235 c gene Dspp was found in a transcriptionally permissive state, while in bone marrow pericytes, the os

236 These alternatives all require prior permissive substitutions that do not enhance the derived

237 ronically contused spinal cord can provide a permissive substrate for the regeneration of certain neu

238 ist E11 infection, enteroendocrine cells are permissive, suggesting that enteroviruses infect specifi

239 cellular apoptosis in a T-cell line (highly permissive SupT1 cells), as well as in primary CD4 T cel

240 ponse (DDR) and cellular apoptosis in highly permissive SupT1 cells, followed by the validation of ou

241 ctive in actomyosin ring assembly at the non-permissive temperature [6, 7].

242 ive and stress-induced autophagic defects at permissive temperature and a secretory defect at restric

243 edling stems, which depends upon a distinct, permissive temperature sensor in the hypocotyl.

244 encodes a partially defective RNase P at the permissive temperature, we show here for the first time

245 in ring contraction when rings isolated from permissive temperature-grown cells are incubated with AT

246 ome lethal in the presence of the drug under permissive temperature.

247 eadthrough was observed in the mutant at the permissive temperature.

248 In Det7, at permissive temperatures TSPs mediate O-antigen cleavage

249 At permissive temperatures, mutant Pop1/6 have little or no

250 Oxidation required viable bacteria at permissive temperatures, which resulted in the generatio

251 ribosomal binding to the ompA transcript at permissive temperatures.

252 We find that TFR cells are more permissive than TFH cells to R5-tropic HIV-1 ex vivo TFR

253 e that these locally induced global, opening-permissive TM motions are indispensable for pore opening

254 patients the bone marrow environment is not permissive to B-cell development.

255 se supramolecular assemblies are shown to be permissive to cell expansion and remodeling, making this

256 ns on a per-cell basis relative to cells not permissive to CT truncation.

257 ed subsets of cells to states that were more permissive to CXCR4 activation, suggesting that such dru

258 quitoes positive for S. marcescens were more permissive to dengue virus infection than those free of

259 thus forming a tripartite lytic pore that is permissive to efflux of potassium.

260 that intestinal epithelial cells (IECs) were permissive to EV-A71 infection, and viral particles were

261 uma concolor samples lacking enFeLV are more permissive to FeLV infection than domestic cat samples,

262 demonstrated that puma fibroblasts are more permissive to FeLV than domestic cat cells, and domestic

263 ng, converting a nonlymphoid tissue into one permissive to functional tertiary lymphoid structure for

264 Here, we show that TFR cells are highly permissive to HIV-1 both ex vivo and in vivo The express

265 tion and puncture (CLP) surgery renders mice permissive to increased B16 melanoma growth weeks/months

266 an infectious center and that NPCs are more permissive to infection by contact with infected cells t

267 mary human fibroblast-like synoviocytes were permissive to infection with Ebola and Marburg viruses i

268 7/9(-/-), and Unc93b1(-/-) cells were highly permissive to L. major replication.

269 tudy, we showed that the zebrafish embryo is permissive to M. kansasii infection, resulting in chroni

270 ollected primary human SCLC tumor cells were permissive to MYXV and intratumoral delivery into patien

271 missive cells but did not render these cells permissive to other FeLV subgroups or feline endogenous

272 a-dependent recruitment of CCR2(+) monocytes permissive to parasite growth.

273 se data indicate that the C8D1A cell line is permissive to prion infection.

274 In contrast, activated B cells were permissive to productive VACV infection.

275 cing mutations and selection of cells highly permissive to RHV replication, which allow study of viru

276 an hamsters, in contrast to mice, are highly permissive to SARS-CoV-2 and develop bronchopneumonia an

277 articularly alveolar type-II-like cells) are permissive to SARS-CoV-2 infection, and showed robust in

278 ic beta cells and liver organoids are highly permissive to SARS-CoV-2 infection, further validated us

279 especially enterocytes, express ACE2 and are permissive to SARS-CoV-2 infection.

280 eins from dog, cat, and cattle were the most permissive to SARS-CoV-2, while bat and bird ACE2 protei

281 tiple barriers or gates that are selectively permissive to specific cargoes.

282 several experimental conditions, and all are permissive to T-ALL.

283 e predict that the heterotypic nucleosome is permissive to the binding of one copy of the kinetochore

284 Prolonging thymus autonomy was shown to be permissive to the development of T cell acute lymphoblas

285 ified by pUbT12 is inaccessible to 53BP1 but permissive to the homologous recombination (HR) proteins

286 cificity, suggesting a developmental context permissive to their effects.

287 ression in cancer cells could make them more permissive to viruses.

288 tely resistant to VSV) or MIA PaCa-2 (highly permissive to VSV) human PDAC cell lines.

289 Therefore, defining which WBCs are permissive to Zika virus (ZIKV) is critical.

290 e developed a nonhuman primate model that is permissive to ZIKV infection and transfers the virus ver

291 re, we demonstrate that Aedes mosquitoes are permissive to ZIKV infection when breeding in urine or s

292 ESCs exhibit permissive topological configurations which manifest the

293 The permissive transmission process characterized here contr

294 cell lines or larvae that were either highly permissive (Trichoplusia ni) or less susceptible (Spodop

295 or-stromal boundary to generate a physically permissive tumor microenvironment for tumor cell invasio

296 The association of permissive underfeeding versus standard feeding and 90-d

297 This is a post hoc analysis of the PermiT (Permissive Underfeeding versus Target Enteral Feeding in

298 To examine the effect of permissive underfeeding with full protein intake compare

299 patients with high and low nutritional risk, permissive underfeeding with full protein intake was ass

300 e of energy stores, water, and sodium within permissive zones.