ライフサイエンスコーパス: persistent infection

1 s its derivative, clone 13 (Cl-13), causes a persistent infection.

2 hat vIL-10 may play a functional role during persistent infection.

3 bud from the plasma membrane and establish a persistent infection.

4 ic treatment for the prolonged duration of a persistent infection.

5 that are maintained in their rodent hosts by persistent infection.

6 n for replication in macaques to establish a persistent infection.

7 gens to evade immune clearance and establish persistent infection.

8 nge of clinical presentations and a lifelong persistent infection.

9 e virus in the establishment of a long-term, persistent infection.

10 rus-induced cardiac disease during acute and persistent infection.

11 in response to hypoxia in vivo, resulting in persistent infection.

12 t support a potential role in primary and/or persistent infection.

13 r phagosomes of the host cells and establish persistent infection.

14 ly important hepatitis B and C viruses cause persistent infection.

15 specimens obtained from subjects developing persistent infection.

16 Ten recipients developed prolonged or persistent infection.

17 elope proteins from HBV in order to maintain persistent infection.

18 vade the host immune response to establish a persistent infection.

19 low in KE37 and BJAB cells, which support a persistent infection.

20 se host microenvironments, thus facilitating persistent infection.

21 ar evolution of that virus during 5 years of persistent infection.

22 urface, rendering them highly susceptible to persistent infection.

23 ll responses and reduce the risk of a second persistent infection.

24 mosquito cell line, wStr maintains a robust, persistent infection.

25 reached germinal center B cells to establish persistent infection.

26 alcitrant nasal polyps, suggesting a link to persistent infection.

27 ful conditions in the host and to maintain a persistent infection.

28 nterobactin and salmochelin are required for persistent infection.

29 ive of a partial protective immunity against persistent infection.

30 stress and antibiotics, and to be sources of persistent infection.

31 in mouse models of acute colitis and chronic persistent infection.

32 nfection of basal cells is a requirement for persistent infection.

33 may be caused by reactivation of a low-level persistent infection.

34 on, ultimately facilitating clearance of the persistent infection.

35 GBV-C is a lymphotropic virus capable of persistent infection.

36 CV infection may facilitate and maintain HCV persistent infection.

37 HTLV-2 or APH-2 mutant viruses established a persistent infection.

38 ral T cell immunity and likely contribute to persistent infection.

39 ant viruses may be the forms responsible for persistent infection.

40 glycoproteins of NDV in the establishment of persistent infection.

41 arance or in mitigating the fitness costs of persistent infection.

42 hers control the pathogen as an asymptomatic persistent infection.

43 o escape host immune clearance and establish persistent infection.

44 cating the presence of a tissue reservoir of persistent infection.

45 mediate a stable standoff during controlled persistent infections.

46 comes a more complex issue in the context of persistent infections.

47 h similar but nonsignificant HRs for 6-month persistent infections.

48 biofilms are responsible for a wide range of persistent infections.

49 med to identify risk factors associated with persistent infections.

50 tunistic pathogen that can cause devastating persistent infections.

51 y 10 to 20% of infections are established as persistent infections.

52 induce a protective immune response against persistent infections.

53 as been documented, leading to nonpathogenic persistent infections.

54 itopes in E2 remained intact throughout both persistent infections.

55 ction detection, but cannot reliably predict persistent infections.

56 issue injury or promote the establishment of persistent infections.

57 ifferentiation is not clear, particularly in persistent infections.

58 or efforts to develop control strategies for persistent infections.

59 tous human pathogens that establish lifelong persistent infections.

60 immune activation and disease progression in persistent infections.

61 omplications occur frequently, especially in persistent infections.

62 nnate inflammatory responses elicited during persistent infections.

63 therapeutic intervention to prevent or treat persistent infections.

64 s and in mice that develop acute followed by persistent infections.

65 o overcome immune dysfunction and thus fight persistent infections.

66 l RNA and is activated by viruses that cause persistent infections.

67 pounds are a promising solution for treating persistent infections.

68 tation and innate immunity in the control of persistent infections.

69 eath, thereby promoting the establishment of persistent infections.

70 ation in the host and serve as catalysts for persistent infections.

71 ral approaches to probe the small numbers in persistent infections.

72 ppeared to be contagious and associated with persistent infections.

73 asive fungi can impair clearance and promote persistent infections.

74 osure with implications for cancer and other persistent infections.

75 difference between responses to primary and persistent infection, 13 long-term carriers were screene

76 E) at 48 months was assessed against 6-month persistent infection (6MPI) with low-risk HPV types in t

77 To establish a persistent infection,A. baumannii must overcome the detr

78 ey B cells in vitro and reproduces acute and persistent infection after oral inoculation of macaques.

79 itro, and successfully established acute and persistent infection after oral inoculation of rhesus ma

80 tently infected patients (P = .043) and with persistent infection among CT patients (P = .033).

81 d human pathogen that establishes a lifelong persistent infection and can cause severe disease in imm

82 . pylori-induced immunomodulation, promoting persistent infection and conferring protection against a

83 i-MPyV CD8 T cells are primed de novo during persistent infection and contribute to maintenance of th

84 squitoes have evolved mechanisms to tolerate persistent infection and developed efficient antiviral s

85 nique hysteretic memory switch may result in persistent infection and enhanced host-to-host spreading

86 egy and is required for the establishment of persistent infection and for viral spread to additional

87 IL-1beta was able to establish a significant persistent infection and immune activation in BALB/c mic

88 nced ability to replicate in mice and caused persistent infection and immune activation in the BALB/c

89 Hepatitis C virus (HCV) often causes persistent infection and is an increasingly important fa

90 associated herpesvirus (KSHV) cause lifelong persistent infection and play causative roles in several

91 LRV1-positive patients (27%) presented with persistent infection and symptomatic relapse that requir

92 dicate that chronic Lyme disease is due to a persistent infection and that extended antibiotic therap

93 at suboptimal Ag presentation contributes to persistent infection and that limiting Ag presentation i

94 t this is a bacterial adaptation to maximize persistent infection and transmission to a new host unde

95 ed by Brucella to establish an intracellular persistent infection and will aid in the development of

96 As the possible exception, VEs against persistent infection and/or CIN 2/3 due to HPV-31 A/B an

97 18, -31, -33, -35, -45, and -51 resulting in persistent infection and/or CIN 2/3 were matched (ratio,

98 reprogram host cells to establish long-term persistent infection and/or to produce viral progeny.

99 iruses, such as hepatitis C virus, establish persistent infections and cause chronic disease are of f

100 ationships of viruses that are able to cause persistent infections and exist with high incidences of

101 ay have an intrinsic ability to cause highly persistent infections and later adverse outcomes.

102 Antiviral resistance is a relevant factor in persistent infections and needs to be investigated in va

103 tory responses in infected ECs, resulting in persistent infections and potential carcinogenesis.

104 s a potential good diagnostic marker for MAP persistent infections and predictor of disease specific

105 otential new target for the immunotherapy of persistent infections and should be accounted for and su

106 90% reduction of incident infection, 6-month persistent infection, and ASCUS+, respectively.

107 This may contribute to the mechanism of HCV persistent infection, and suggest that blockade of HCVc

108 During many persistent infections, antiviral T cells are maintained

109 of Msp2 variants expressed during long-term persistent infection are mosaics, derived by recombinati

110 Persistent infections are common, and there is currently

111 Because repeated or persistent infections are correlated with serious compli

112 mechanisms associated with establishment of persistent infections are poorly elucidated.

113 lococcus aureus biofilms, a leading cause of persistent infections, are highly resistant to immune de

114 In persistent infection, arginase-expressing gMDSCs (and ci

115 ctive immune responses and, thereby, promote persistent infections, as evidenced by studies of crypto

116 n persist in large numbers during controlled persistent infections, as exemplified by rare HIV-infect

117 virus infections, which can cause acute and persistent infections associated with chronic inflammati

118 mal disease at cutaneous sites but developed persistent infection at the mucosal sites including thos

119 y associated with lower risk of incident and persistent infection, atypical squamous cells of undeter

120 s, such as Epstein-Barr virus, can establish persistent infection, but the underlying virus-host inte

121 infections might be due to reactivation of a persistent infection, but this hypothesis has been diffi

122 approximately 2000 years ago as a result of persistent infection by a fungal endophyte, Ustilago esc

123 oprotein of hepatitis C virus contributes to persistent infection by evolving escape mutations that a

124 HVR1 contributes to persistent infection by evolving mutations that escape f

125 r understand the dynamic interaction between persistent infection by HTLV-I and virus-specific host i

126 regions of HCV genomes appear to facilitate persistent infection by masking the genome from RNase L

127 proteasomal degradation and is necessary for persistent infection by Mtb.

128 Persistent infection by specific oncogenic human papillo

129 This persistent infection can cause severe disease in immunoc

130 de of these pathways either before or during persistent infection can promote viral clearance.

131 ght to be important in the dissemination and persistent infection caused by ranavirus.

132 Persistent infections caused by pathogens such as hepati

133 ble-stranded DNA viruses that cause lifelong persistent infections characterized by periods of quiesc

134 Persistent infection (chronic Q fever) develops in 1%-5%

135 virus-specific CD8 T cells recruited during persistent infection contribute to preservation of funct

136 work in the murine norovirus (MNV) model of persistent infection demonstrates that innate immunity c

137 ms that the parasite utilizes to establish a persistent infection despite activation of a potent immu

138 Many bacterial pathogens cause persistent infections despite repeated antibiotic exposu

139 cobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific

140 letion of genes from the wca operon caused a persistent-infection E. coli strain to become sensitive

141 In fact, persistent infections following antibiotic treatment are

142 n, human herpesvirus 6 (HHV-6) establishes a persistent infection for life.

143 ibular salivary gland (SMG), a major site of persistent infection for many viruses, contains a large

144 ient-derived hepatitis B virus can establish persistent infection for over 30 days in a self-assembli

145 Here, we show that NPHV, like HCV, can cause persistent infection for over a decade, with high titers

146 eficiency virus type 1 (HIV-1) establishes a persistent infection for which there remains no feasible

147 Incident and 6-month persistent infections for HPV 6 and 11 did not differ by

148 Lifelong persistent infection has also been linked with the devel

149 populations during the course of a lifelong, persistent infection has generated interest in the virus

150 fic CD4 T cells primed during an established persistent infection have diminished ability to develop

151 Prior studies in mouse models of persistent infection have suggested that ineffective ada

152 tramacrophage environment may be a niche for persistent infection; however, mechanisms by which the b

153 Whereas immune-compromised mice developed persistent infection, immune-competent mice cleared the

154 V infection is that it establishes long-term persistent infection in 10 to 70% of infected stallions

155 It provides the only example to date of persistent infection in a chimpanzee challenged with cel

156 We explore the emergence of persistent infection in a closed region where the diseas

157 However, E. coli has been shown to cause a persistent infection in a minority of cases.

158 LB/c, and C3H/HeN mice and induced lethal or persistent infection in a route- and dose-dependent mann

159 ewcastle disease virus (NDV) could establish persistent infection in a tumor cell line, resulting in

160 ingly, pp65 was not required for primary and persistent infection in animals.

161 Alphaviruses establish a persistent infection in arthropod vectors which is essen

162 ies to hijack infected host cells, establish persistent infection in B cells, and evade antiviral imm

163 hagic fever in macaques but an asymptomatic, persistent infection in baboons.

164 in neonatal-infected mice diversified during persistent infection in both the brain and spleen, while

165 Biofilms facilitate colonization and persistent infection in gallbladders of humans and mouse

166 CD4(+) T cells are the largest reservoir of persistent infection in HIV-1-positive subjects.

167 e that this anatomical site is the source of persistent infection in humans.

168 ubiquitous virus that establishes a lifetime persistent infection in humans.

169 M. tuberculosis that allows establishment of persistent infection in lymph nodes.

170 The inability to establish a persistent infection in mice, even in immunocompromised

171 utritional immunity in macrophages and cause persistent infection in mice.

172 Hepatitis C virus (HCV) establishes persistent infection in most infected patients, and even

173 HIV-1 establishes persistent infection in part due to its ability to evade

174 /ESI-MS may be a very sensitive indicator of persistent infection in patients on antibiotic therapy f

175 wn as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B,

176 We also detected a higher frequency of persistent infection in PML(-)/(-) peritoneal cells.

177 Hantaviruses cause a persistent infection in reservoir hosts that is attribut

178 re large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly man

179 was required for MRSA to achieve high-level, persistent infection in the bladder.

180 ment of macrophages and establish long term, persistent infection in the host against the control of

181 form of the virus and thought to establish a persistent infection in the host urinary tract.

182 mavirus (JCPyV) establishes an asymptomatic, persistent infection in the kidneys of the majority of t

183 may also contribute to the establishment of persistent infection in the liver.

184 Hepatitis C virus (HCV) causes persistent infection in the majority of infected individ

185 emiological and clinical features, including persistent infection in the male reproductive tract and

186 DeltacheY2-infected ticks did not develop a persistent infection in the murine host.

187 full MCMV infectivity in macrophages and for persistent infection in the salivary gland.

188 mia suggest the ability of ZIKV to establish persistent infection in the seminiferous tubules, an imm

189 rus has the distinctive ability to establish persistent infection in the stallion's reproductive trac

190 including severe congenital manifestations, persistent infection in the testes, and neurologic seque

191 that plays an essential role in establishing persistent infection in their respective host species.

192 g human pathogens maintained by noncytolytic persistent infection in their rodent reservoir hosts.

193 hagocytic or endothelial cells and establish persistent infection in their vertebrate reservoir hosts

194 that is consistent with the establishment of persistent infection in tissue macrophages.

195 Thus, establishment of persistent infection in vitro involves viral genetic cha

196 coma-associated herpesvirus (KSHV) establish persistent infections in B cells.

197 omaviruses are characterized by establishing persistent infections in healthy hosts and generally cau

198 as aeruginosa biofilm formation is linked to persistent infections in humans.

199 ve genus of retroviruses that cause chronic, persistent infections in mammals, including humans.

200 t the surprising finding that during ongoing persistent infections in mice, a major fraction of the p

201 y feature of viruses that establish lifelong persistent infections in the face of strong immune respo

202 re zoonotic viruses that cause asymptomatic, persistent infections in their rodent hosts but can lead

203 difficile Spo0A protein plays a key role in persistent infection, including recurrence and host-to-h

204 The accelerated control of persistent infection induced by blocking IFN-I signaling

205 tection, 214 were untreated (n = 137) or had persistent infection (infection duration >/=26 weeks) at

206 Persistent infection is a key feature of hepatitis C vir

207 ommon cause of infectious mononucleosis, and persistent infection is associated with multiple cancers

208 or therapy in immunocompromised persons with persistent infection is limited because of cost, determi

209 heck-point function of the spleen to promote persistent infection is not clear.

210 of naive CD4 T cells primed in the midst of persistent infection is unclear.

211 How such enteric viruses establish persistent infections is not well understood.

212 esistant Staphylococcus aureus (MRSA) during persistent infection leads to antimicrobial resistance b

213 Such persistent infections may provide the opportunity for th

214 murine cytomegalovirus (MCMV) was used as a persistent infection model to study heterologous immunit

215 o spontaneously cleared HCV (n = 285) or had persistent infection (n = 509).

216 Other potential causes of persistent infection need to be evaluated.

217 ogic loads of M. genitalium, suggesting that persistent infection occurs with minimal direct damage t

218 f DC vaccine in preventing and combating the persistent infection of HCV or other chronic viruses.

219 Persistent infection of hepatitis C virus (HCV) is one o

220 may have evolved to allow HBoV1 to establish persistent infection of human airway epithelia.

221 nded to persist over time, suggesting either persistent infection of individuals or cycles of reinfec

222 ising in the viral capsid protein VP1 during persistent infection of mice.

223 Thus, persistent infection of phagocytes produced a CD4(+) T c

224 We detected persistent infections of Mycoplasma ovipneumoniae, the p

225 Despite this, SCVs are associated with persistent infections of the bloodstream, bones, and pro

226 iasis (CMC) is characterized by recurrent or persistent infections of the skin, nail, oral, and genit

227 ndpoint was vaccine efficacy against 6-month persistent infection or cervical intraepithelial neoplas

228 ndpoint was vaccine efficacy against 6-month persistent infection or cervical intraepithelial neoplas

229 r efficacy, vaccine efficacy against 6-month persistent infection or CIN1+ associated with HPV 16/18

230 e efficacy against HPV 16/18-related 6-month persistent infection or CIN1+ was significant in all age

231 aintenance, function, and response to latent persistent infection, particularly against CMV, which ex

232 comparing temporally dispersed isolates from persistent infections (persistent isolates) originating

233 cells were infected with Sendai virus (SeV), persistent infection (PI) was established.

234 Of these 15 patients, 3 died from persistent infection postoperatively, whereas 8 underwen

235 ic CD4 T cells primed during the established persistent infection provide help to B cells, but only l

236 ART usage was associated with a higher TV persistent infection rate among those receiving the sing

237 erfering with chronic IFN-I signaling during persistent infection redirects the immune environment to

238 hough the evolving immune environment during persistent infection reshapes established CD4 T-cell res

239 nd Ab-mediated immunity to control acute and persistent infection, respectively.

240 he host defense system to facilitate its own persistent infection, resulting in a compromise of the m

241 following an RC treatment (RCT) can lead to persistent infections, resulting in treatment failure an

242 2 mutations arising in clinical MRSA during persistent infection: RpoB H(4)(8)(1)Y, which is linked

243 Unlike human malaria parasites that induce persistent infection, some rodent malaria parasites, lik

244 Deletion of genes in the wca operon from a persistent-infection strain resulted in a reduction of m

245 er is a tolerogenic environment exploited by persistent infections, such as hepatitis B (HBV) and C (

246 SHV proteins v-FLIP and v-cyclin during KSHV persistent infection that reshapes autophagy.

247 gulation of metabolic processes during early persistent infection that was linked to changes in expre

248 us or human herpesvirus 8 (HHV-8), establish persistent infections that cause chronic illnesses, incl

249 During persistent infection, the E2 proteins from many papillom

250 To maintain a persistent infection, the expression of ap2-g is limited

251 indeed EBV-2 utilizes T cells to establish a persistent infection, this could provide one mechanism f

252 ance of a limited CD8 T cell response during persistent infections, this response is not sufficiently

253 ctively, this study shows that CTLs adapt to persistent infection through a positive feedback pathway

254 s a common human pathogen that establishes a persistent infection through latency in B cells, where i

255 ology during RCT has the potential to reduce persistent infections through vital cell detection and a

256 g acute infection, the role of vIL-10 during persistent infection was analyzed in rhesus macaques inf

257 Persistent infection was associated with increased and s

258 In contrast, persistent infection was asymptomatic and led to establi

259 that clear infection and those that develop persistent infection was demonstrated to occur earlier t

260 CAR3) with a recombinant low-pathogenic NDV, persistent infection was established in a subset of tumo

261 The risk of incident and 6-month persistent infection was not associated with baseline se

262 Persistent infection was observed in all cases.

263 ptomatic (because they were healthy troops), persistent infection we called the primary multiple scle

264 Using the J-Lat 10.6 model of persistent infection, we demonstrate that proliferation

265 Persistent infections were acquired at an earlier age, a

266 demonstrated that E. coli strains that cause persistent infections were more motile than those that c

267 limited by reduced antigen expression during persistent infection, whereas ESAT-6-specific T cells be

268 viral genome into the host cell, leading to persistent infection wherein HIV-1 can remain transcript

269 n worldwide, predominantly originates from a persistent infection with a high-risk human papillomavir

270 lidity of results of attempts to demonstrate persistent infection with B. burgdorferi has not been es

271 Due to the high prevalence of persistent infection with BKV in the general population,

272 This first persistent infection with cell culture-produced HCV prov

273 Here, we report persistent infection with chronic hepatitis in a chimpan

274 Liver disease associated with persistent infection with hepatitis B virus (HBV) contin

275 Persistent infection with hepatitis C virus (HCV) causes

276 shed that chronic antigen stimulation during persistent infection with hepatitis C virus is associate

277 host and body louse vector niches, producing persistent infection with high titer bacterial loads in

278 Persistent infection with high-risk human papillomavirus

279 ion is harmless and clears spontaneously but persistent infection with high-risk human papillomavirus

280 nt cross-protective efficacy against 6-month persistent infection with HPV 31 (65.8%, 96.2% CI 24.9-8

281 -protective vaccine efficacy against 6-month persistent infection with HPV 31 (79.1%, 97.7% CI 27.6-9

282 Cervical cancer is a consequence of persistent infection with human papillomaviruses (HPV).

283 Immune control of persistent infection with Mycobacterium tuberculosis (Mt

284 Persistent infection with oncogenic Human Papillomavirus

285 Persistent infection with oncogenic human papillomavirus

286 uman lymphocytes survive while maintaining a persistent infection with species C adenovirus, we compa

287 ne appears to have moderate efficacy against persistent infections with a number of low-risk HPV type

288 nd immune pathology associated with acute or persistent infections with an unrelated virus.

289 Persistent infections with cytomegalovirus (CMV) differe

290 ociated with sex, birth characteristics, and persistent infections with cytomegalovirus (CMV) or EBV.

291 Persistent infections with hepatitis B virus (HBV) or he

292 fundamentally in their ability to establish persistent infections with markedly different patterns o

293 i infection display features common to other persistent infections with signs of T cell exhaustion.

294 of that ST in that herd (index case) and all persistent infections with that PTE ST, represented 40%

295 cy virus positive (HIV+), both prevalent and persistent infections with Trichomonas vaginalis (TV) ar

296 h hepatitis C virus (HCV) typically leads to persistent infection, with >170 million people estimated

297 nd potent responses are uncommon even during persistent infection, with only a subset of adults devel

298 e samples as a result of niche adaptation to persistent infection within a host.

299 evasion strategies used by HCV to establish persistent infection within the liver, as well as how ho

300 f Staphylococcus aureus disease in humans is persistent infections without development of protective