ライフサイエンスコーパス: petrobactin

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1 cluding SbnE in staphyloferrin B and AsbA in petrobactin.

2 -stage products leading to final assembly of petrobactin.

3 escued by the addition of exogenous purified petrobactin.

4 s that are linked to citrate for assembly of petrobactin.

5 measured for vibrioferrin, rhizoferrin, and petrobactin.

6 ical studies suggested that using the native petrobactin 1b for M. hydrocarbonoclasticus-specific gro

7 A modular synthesis was developed to access petrobactin, a catechol-containing siderophore isolated

8 anthracis is responsible for biosynthesis of petrobactin, a catecholate siderophore that functions in

9 Petrobactin, a mixed catechol-carboxylate siderophore, i

10 , targeted inhibition of the biosynthesis of petrobactin, a virulence-associated siderophore encoded

11 Petrobactin, a virulence-associated siderophore produced

12 this strain demonstrated increased levels of petrobactin accumulation in the culture supernatants, su

13 The synthesis of petrobactin and its homologues and the first biological

14 DeltafpuBDeltafatCD, was incapable of using petrobactin as an iron source and exhibited attenuated v

15 ies to determine the biosynthetic details of petrobactin assembly based on mutational analysis of the

16 talyzes formation of amide bonds crucial for petrobactin assembly through use of biosynthetic interme

17 ed allowing for characterization of multiple petrobactin ATP-binding cassette (ABC)-import systems.

18 ere we demonstrate the roles of two putative petrobactin binding proteins FatB and FpuA (encoded by G

19 The petrobactin-binding receptor FpuA is required for these

20 mutations resulted in complete abrogation of petrobactin biosynthesis when strains were grown on iron

21 tudies have revealed selected early steps in petrobactin biosynthesis, the origin of 3,4-DHBA as well

22 (DHB-SP), the first isolable intermediate in petrobactin biosynthesis.

23 iron (efeUOB), ferric citrate (fecCDEF), and petrobactin (fpbNOPQ) are induced to prevent iron defici

24 The siderophore petrobactin harbors unique 3,4-dihydroxybenzoyl iron-lig

25 A range of petrobactin homologues with differing dihydroxybenzamide

26 pic characteristics of a mutant deficient in petrobactin import.

27 d ATPase proteins required for the import of petrobactin in B. anthracis.

28 the recently revised structure showing that petrobactin in fact contains a 3,4-dihydroxybenzene moti

29 the penultimate step in the biosynthesis of petrobactin, involving condensation of 3,4-dihydroxybenz

30 In Bacillus anthracis, the siderophore petrobactin is required for both growth in iron-depleted

31 In Bacillus anthracis the siderophore petrobactin is vital for iron acquisition and virulence.

32 taphyloferrin B of Staphylococcus aureus and petrobactin of Bacillus anthracis hold considerable pote

33 shown to encode the complete transporter for petrobactin (PB), a photoreactive 3,4-catecholate sidero

34 ete two siderophores, bacillibactin (BB) and petrobactin (PB), for iron acquisition via membrane-asso

35 les, the siderophores bacillibactin (BB) and petrobactin (PB).

36 ihydroxybenzoate moieties of the siderophore petrobactin, produced by B. anthracis str.

37 Here additional components of petrobactin reacquisition are described.

38 contrast, the unusual 3,4-DHBA component of petrobactin renders the siderocalin system incapable of

39 iron acquisition and play redundant roles in petrobactin transport.

40 c evidence demonstrating the role of FpuA in petrobactin uptake.

41 that FatB does not play an essential role in petrobactin uptake.

42 t for conversion of endogenous precursors to petrobactin using an in vitro system.

43 ve products of AsbB are further converted to petrobactin, verifying previously proposed convergent ro

44 Provision of exogenous petrobactin was able to rescue the growth defect in each

45 Both the (1)H and (13)C NMR of petrobactin were consistent with the recently revised st

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