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1 xposed to aerosolized monkeypox virus (10(5) PFU).
2 nuates mouse neuroinvasiveness (>/=1,000,000 PFU).
3 : wild-type mice, 10 PFU; CD1(-/-) mice, 1.6 PFU).
4 ted (1 received 100 PFU, and 2 received 1000 PFU).
5 PFU, 3 received 100 PFU, and 3 received 1000 PFU).
6 during pregnancy with wild-type GPCMV (10(5) PFU).
7 eroconverted (the seroconverter received 100 PFU).
8 AST mice, whereas BALB/c mice survived 10(6) PFU.
9 persisted up to day 180 for doses >/=3 x 105 PFU.
10 ge at a median protective dose (PD50) of 2.4 PFU.
11 4 x 10(5) PFU; (NA+HA)(Min), >/=3.16 x 10(6) PFU.
12 of 800-2200 PFU and a detection limit of 600 PFU.
13 ven after intracerebral inoculation of 10(3) PFU.
14 e PKR(-/-) mice succumbed at a dose of 10(8) PFU.
15 ring in animals infected with 10(6) or 10(7) pfu.
16 intraperitoneal route, with an LD(50) of 14 PFU.
17 est African clade yielded an LD(50) of 7,600 PFU.
18 ted elevated ratios of virion DNA copies per PFU.
19 which reached, respectively, 0.005 and 0.017 PFU.
20 able dose of 50 PFU and a lethal dose of 500 PFU.
21 than 50% of participants at doses >/=3 x 105 PFU.
22 ainst RSV challenge at doses as low as 10(3) PFU.
23 ose vaccinated with 3 million or 100 million PFU.
24 doses of EBOV (</=100 plaque-forming units [PFU]).
25 ting Bacteroides GB-124 (mean = 4.36 log(10) PFU/100 mL) and that GB-124 phages, HAdV, and NoV were a
26 centrations of 1.71 x 10(2) and 4.27 x 10(2) PFU/100 mL, respectively, higher than nonhost specific R
27 tly reduced specific infectivity (si) (WT, 1 PFU/118 particles vs. P2(Min), 1 PFU/35,000 particles),
28 BOV vaccine (3 million plaque-forming units [PFU], 20 million PFU, or 100 million PFU) or placebo.
32 (si) (WT, 1 PFU/118 particles vs. P2(Min), 1 PFU/35,000 particles), a phenotype that will be discusse
33 paratuberculosis cells ranging from 1 to 110 PFU/50 ml of milk and 6 to 41,111 PFU/g of feces were in
34 vaccinees (22%) receiving 10(7) or 5 x 10(7) pfu, 56 participants were given a lower dose (3 x 10(5)
36 e upper and lower airways by 3.8 log10 total PFU and 2.7 log10 PFU/g of tissue, respectively, compare
40 illion and 100 million plaque-forming units (PFU) and homologous VSV-Ebola vaccine boost in healthy a
42 negative nPKCepsilon (Ad DNPKCepsilon, 10(4) pfu), and wild-type cPKCalpha (Ad WTPKCalpha, 10(7) pfu)
45 llion or 100 million PFU than with 3 million PFU, and these correlated strongly with neutralization t
46 ase (Ad-Cre; 2 x 10(7) plaque forming units [PFU]) and adeno-associated viral vectors expressing VEGF
49 FU than in the group that received 3 million PFU, as assessed by ELISA and by pseudovirion neutraliza
54 .i.]) after maximal virus titers (150 to 200 PFU/cell) have been reached, with loss of most infectiou
55 ing infection at low multiplicity (MOI = 0.1 PFU/cell) inhibited HCMV in a dose-dependent manner and
56 a low multiplicity of infection (MOI; 0.0001 PFU/cell) or with 2009 pandemic H1N1 viruses at a high M
58 (viability: control, 33.02+/-1.09%; LacZ 10 pfu/cell, 32.85+/-1.51%; catalase 1 pfu/cell, 62.09+/-4.
59 LacZ 10 pfu/cell, 32.85+/-1.51%; catalase 1 pfu/cell, 62.09+/-4.17%*; catalase 2 pfu/cell, 98.71+/-3
60 alase 1 pfu/cell, 62.09+/-4.17%*; catalase 2 pfu/cell, 98.71+/-3.35%*; catalase 10 pfu/cell, 99.68+/-
61 lase 2 pfu/cell, 98.71+/-3.35%*; catalase 10 pfu/cell, 99.68+/-1.99%*; *p<0.05 vs. control; mean+/-SE
62 ime of intranasal (10(6) PFU) or i.p. (10(7) PFU) challenge with virus resulted in complete protectio
65 challenging the animals with 10(5) or 10(6) PFU Congo Basin MPXV 30 days postvaccination and evaluat
66 s, we evaluated cellular responses and viral PFU counts in murine RAW264.7 cells and primary macropha
68 we evolved a version of Pyrococcus furiosus (Pfu) DNA polymerase that tolerates modification of the g
71 ant-negative cPKCalpha (Ad DNPKCalpha, 10(4) pfu), dominant-negative nPKCepsilon (Ad DNPKCepsilon, 10
73 ty and immunogenicity profile of the 2 x 107 PFU dose in adults and support consideration of lower do
80 affected the severity of disease, with 10(4) pfu eliciting milder keratitis after delayed onset compa
83 ritoneal dose of vaccinia virus (VACV) was 3 PFU for CAST mice, whereas BALB/c mice survived 10(6) PF
85 on threshold was 0.017 PFU for DENV-1, 0.004 PFU for DENV-2, 0.8 PFU for DENV-3, and 0.7 PFU for DENV
88 evaluation of the vaccine dose of 20 million PFU for preexposure prophylaxis and suggest that a secon
90 m 1 to 110 PFU/50 ml of milk and 6 to 41,111 PFU/g of feces were indicated by the PMS-phage assay.
91 airways by 3.8 log10 total PFU and 2.7 log10 PFU/g of tissue, respectively, compared to those in unva
93 r LD50 values: PR8, 32 plaque-forming units (PFU); HA(Min), 1.7 x 10(3) PFU; NA(Min), 2.4 x 10(5) PFU
96 x 103, 3 x 104, 3 x 105, 3 x 106, or 2 x 107 PFU in 115 adults and a dose of 2 x 107 PFU in 20 adoles
98 d, at best, provided a visual read of 10-100 pfu in a 100-microL sample when a colorimetric substrate
104 -dose (2 x 10(8) PFU) or low-dose (1 x 10(7) PFU) intramuscular immunization of rhesus macaques.
105 d to vaccination with a high dose (2,000,000 PFU), intranasal inoculation with a low dose (200 PFU) r
107 ations of MS2 and Phi6 were approximately 20 PFU L(-1) and approximately 0.1 PFU L(-1), respectively,
108 oximately 20 PFU L(-1) and approximately 0.1 PFU L(-1), respectively, in the chambers enclosing the a
111 med by the limit of detection (as low as 0.1 PFU/microL, equivalent to copy number of 4.9) in spiked
112 respectively, for the aeration basin and 79 PFU min(-1) and 0.3 PFU min(-1) for the sewer pipes.
113 ding emission rates of MS2 and Phi6 were 547 PFU min(-1) and 3.8 PFU min(-1), respectively, for the a
115 of MS2 and Phi6 were 547 PFU min(-1) and 3.8 PFU min(-1), respectively, for the aeration basin and 79
118 and dengue 3 viruses in plaque forming unit (PFU mL(-)(1)), giving detection limit of 0.230 PFU mL(-)
119 reporter phage concentration of 1.76 x 10(2) pfu ml(-1) are capable of detecting approximately 5 CFU
120 s achieved within 9 hours using 9.23 x 10(3) pfu ml(-1) of phage in selective culture enrichments of
121 n a linear range from 5 x 10(4) to 5 x 10(6) PFU mL(-1) with a detection limit of 10(4) PFU mL(-1).
122 of 3-45 plaque-forming units per milliliter (pfu mL(-1)) with detection limit of 0.04 pfu mL(-1), com
123 f 10(7) plaque-forming units per milliliter (PFU mL(-1)), were not detected in air after flushing.
124 er (pfu mL(-1)) with detection limit of 0.04 pfu mL(-1), comparable to state-of-the-art polymerase ch
126 EBOV and SUDV were 465 plaque-forming units (PFU)/mL (1010 copies/mL) and 324 PFU/mL (8204 copies/mL)
128 lectric signal up to 10 Plaque forming unit (PFU)/mL with a limit of detection (LOD) of 8.75 PFU/mL.
130 D) of the dual-channel PSPWB for S-OIV is 30 PFU/mL (PFU, plaque-forming unit), which was calculated
131 ects and allowed low limits of detection (12 pfu/mL and 39 pfu/mL in buffer and in river water, respe
132 lent sensitivity and limit of detection (9.3 pfu/mL and 9.8 pfu/mL in buffer and in river water, resp
133 ent specificity, a limit of detection of 0.2 pfu/mL and a dynamic range of thirteen orders of magnitu
134 15 min with reasonable sensitivity of 10(7) pfu/mL and minimal sample preparation, making this trans
135 ed low limits of detection (12 pfu/mL and 39 pfu/mL in buffer and in river water, respectively) that
136 y and limit of detection (9.3 pfu/mL and 9.8 pfu/mL in buffer and in river water, respectively) were
137 mmunosensor showed a limit of detection of 6 pfu/mL in buffer, allowing the detection of MS2 to level
138 ured S-OIV at a concentration of 1.8 x 10(2) PFU/mL in mimic solution, which contained PBS-diluted no
140 ntrations, followed by incubation with 10(3) PFU/ml of D29 mycobacteriophage for 24 h and then real-t
141 ed peak viremia titers of 2.8 to 3.1 log(10) PFU/ml on day 2 or 4 after infection, but there was no d
142 accine groups given doses of 10(6.6)-10(7.2) pfu/mL than for those given doses of 10(7.6)-10(8.2) pfu
143 detection range was determined to be from 10 PFU/mL to 5000 PFU/mL with an R(2) value greater than 0.
145 e recombinant RVs grew to high titer (>10(7) PFU/ml) and remained genetically stable during serial pa
146 cate rapidly and to high titer (up to 10(10) PFU/ml) in mosquito cells, producing extensive cytopathi
147 rVSVDeltaG*/BDVG produced high titers (10(7) PFU/ml) of cell-free virus progeny, but this virus exhib
150 restored release of infectious virus (>10(6) PFU/ml), confirming that SKI-1/S1P processing is require
159 tely expressed and purified fragments, split Pfu mutant behaves identically to wild-type DNA polymera
160 ad received 1 x10(7) pfu (n=35) or 5 x 10(7) pfu (n=16) of rVSV-ZEBOV (high-dose vaccinees) or placeb
161 with 59 volunteers who had received 1 x10(7) pfu (n=35) or 5 x 10(7) pfu (n=16) of rVSV-ZEBOV (high-d
162 igh-dose lot of rVSVDeltaG-ZEBOV-GP (1 x 108 pfu, n = 264; high-dose group), or placebo (n = 133).
163 ticipants were given a lower dose (3 x 10(5) pfu, n=51) or placebo (n=5) to assess the effect of dose
164 taG- ZEBOV-GP (2 x 107 plaque-forming units [pfu], n = 797; combined-lots group), a single high-dose
165 ue-forming units (PFU); HA(Min), 1.7 x 10(3) PFU; NA(Min), 2.4 x 10(5) PFU; (NA+HA)(Min), >/=3.16 x 1
167 n the absence of hormone pretreatment, 2,000 PFU of a clinical isolate of HSV-2 was sufficient to est
168 ed groups of swine with a control Ad5, 10(8) PFU of Ad5-pIFN-alpha, low- or high-dose Ad5-pIFN-gamma,
169 at pigs treated with 10(8), 10(9), or 10(10) PFU of Ad5-poIRF7/3(5D) 24 h before FMDV challenge were
171 was evaluated following inoculation of 10(7) PFU of Delta145 or parental virus into guinea pigs immun
172 guinea pigs twice with either 10(5) or 10(6) PFU of Delta145, establishing pregnancy, and challenging
179 Following corneal infection with 2 x 10(6) PFU of HSV-1 strain McKrae, 50% of wild-type mice surviv
180 ell culture, and swine inoculated with 10(9) PFU of human adenovirus type 5 expressing porcine IFN-al
181 10(5) T cells prior to challenge with 10(4) PFU of IHD-J-Luc and treated with BCV postchallenge surv
182 organs, and survived rechallenge with 10(5) PFU of IHD-J-Luc VACV without additional BCV treatment.
184 ranscribed RNA/reaction or approximately 0.1 PFU of infectious virus/reaction) and efficiency (standa
185 eral vaccination of mice with 10(1) or 10(3) PFU of JCV/LACV protected against lethal challenge with
186 (NAb) from TDV were revaccinated with 10(4) PFU of live attenuated DENV-3 vaccine to evaluate memory
187 ld-type) mice were inoculated with 5 x 10(4) PFU of MCMV K181 strain (K181) via the supraciliary rout
188 were inoculated intraperitoneally with 10(7) PFU of parental or recombinant SV40 viruses and were obs
189 infected via the intranasal route with 10(5) PFU of recombinant IHD-J-Luc VACV expressing luciferase.
190 ely resistant to i.c. inoculation with 10(6) PFU of recombinant wild-type MHV-A59 (RA59) virus, these
192 accinated orally with a single dose of 10(8) PFU of rPIV5-RV-G showed a 50% survival rate, which is c
193 mice vaccinated with a single dose of 10(8) PFU of rPIV5-RV-G via the i.m. route showed very robust
195 STAT2 are highly susceptible to as few as 10 PFU of SFTSV, with animals generally succumbing within 5
196 ue-forming units [PFU] of TDV-1; 6.3 x 10(3) PFU of TDV-2; 3.2 x 10(4) PFU of TDV-3; and 4.0 x 10(5)
197 TDV-1; 6.3 x 10(3) PFU of TDV-2; 3.2 x 10(4) PFU of TDV-3; and 4.0 x 10(5) PFU of TDV-4) in different
198 2; 3.2 x 10(4) PFU of TDV-3; and 4.0 x 10(5) PFU of TDV-4) in different dose schedules (two-dose regi
201 hat infection of C57BL/6 mice with 1 x 10(7) PFU of vaccinia virus strain WR results in blepharitis,
202 time of intranasal challenge with 2 x 10(6) PFU of vaccinia virus, resulted in complete protection a
203 ainst viremia when challenged with 1 x 10(5) pfu of virulent RVF virus delivered by a small particle
204 nd human embryonic lung cells exposed to 0.1 pfu of virus per cell was 100-, 10-, and 10-fold higher,
209 he anti-ZIKV-PSBs can capture as little as 1 PFU of ZIKV in 100 mul of saline, human plasma, or human
210 laterally with 2x10(6) plaque-forming-units (PFU) of adenovirus type 5 (Ad5) after corneal scarificat
214 5 x 10(4) or 1 x 10(5) plaque-forming units (pfu) of Rift Valley fever (RVF) MP-12 vaccine by oral, i
215 10(5), 10(6), or 10(7) plaque-forming units (pfu) of the Dryvax strain of the vaccinia virus and scor
216 rs receiving 3 x 10(5) plaque-forming units (pfu) of the recombinant vesicular stomatitis virus-based
217 containing 2.5 x 10(4) plaque-forming units [PFU] of TDV-1; 6.3 x 10(3) PFU of TDV-2; 3.2 x 10(4) PFU
218 ral titers peaked at approximately 1 x 10(6) PFU on day 5 postinfection, and virus had not cleared by
222 igher in the groups that received 20 million PFU or 100 million PFU than in the group that received 3
223 e 130 participants (95%) receiving 3 million PFU or more; rVSV was not detected in saliva or urine.
224 ing sizes to a single injection of 3 x 10(5) pfu or placebo, whereas deployable participants received
228 before and at the time of intranasal (10(6) PFU) or i.p. (10(7) PFU) challenge with virus resulted i
229 gimens utilizing either high-dose (2 x 10(8) PFU) or low-dose (1 x 10(7) PFU) intramuscular immunizat
230 ants received low-dose rVSV-ZEBOV (3 x 10(5) pfu) or placebo in a double-blind fashion, whereas 13 de
234 ose-dependent decrease in the level of vRNA, PFU, or [RTP]/[GTP] (where RTP is ribavirin-5'-triphosph
241 amount of infectious virus that we detected (PFU per viral antigen-positive neuron) was similar to th
244 atalase, with up to 10 plaque forming units (pfu) per neuron, did not affect cell viability under con
245 e dual-channel PSPWB for S-OIV is 30 PFU/mL (PFU, plaque-forming unit), which was calculated from the
246 y B DNA polymerase from Pyrococcus furiosus (Pfu Pol) contains sensitive determinants of both dNTP bi
248 PCR amplification using a high-fidelity DNA Pfu polymerase generating a plasmid containing staggered
249 f primer-templates with Pyrococcus furiosus (Pfu) polymerase-DNA complexes containing uracil at +2; m
250 e the three-dimensional structure of PF1378 (Pfu Pop5), one of four protein subunits of archaeal RNas
251 A-inactivated ZEBOV (equivalent to 5 x 10(4) pfu) protected mice against lethal challenge with 1000 p
252 to receive 2 x NYVAC-B followed by 1 x 1010 PFU rAd5 (NYVAC/Ad5hi); 1 x 108 PFU rAd5 followed by 2 x
253 owed by 2 x NYVAC-B (Ad5med/NYVAC); 1 x 1010 PFU rAd5 followed by 2 x NYVAC-B (Ad5hi/NYVAC); or place
254 by 1 x 1010 PFU rAd5 (NYVAC/Ad5hi); 1 x 108 PFU rAd5 followed by 2 x NYVAC-B (Ad5lo/NYVAC); 1 x 109
255 llowed by 2 x NYVAC-B (Ad5lo/NYVAC); 1 x 109 PFU rAd5 followed by 2 x NYVAC-B (Ad5med/NYVAC); 1 x 101
256 5 cells, and the viral genome copy number-to-PFU ratio for VZV in human neurons was 500, compared wit
257 ampered by the fact that the VZV particle-to-PFU ratio has never been determined with precision.
258 4,000- to 20,000-fold increased) particle-to-PFU ratio in vitro than herpes simplex virus (HSV).
259 es, on average, exhibit a higher particle-to-PFU ratio than mosquito cell-derived SINV particles.
260 ay not necessarily have a higher particle-to-PFU ratio than other herpesviruses; instead, the cells p
261 Based on these numbers, the VZV particle:PFU ratio was approximately 40,000:1 for a cell-free ino
264 ll lines (SINV(C6/36)) exhibited particle-to-PFU ratios similar to those observed for SINV(Heavy).
267 d increased physical to infectious particle (PFU) ratios, with additional data suggesting that a late
270 aline, 1 x 10(6) (BOOP), or 1 x 10(7) (ARDS) PFU reovirus 1/L, and evaluated at various days postinoc
272 e (LD(5)(0)) values of 0.1 and 0.5 log(1)(0) PFU, respectively, chimeric JCV/LACV is highly attenuate
274 nge with doses of r129 virus of >/=5 x 10(6) PFU resulted in levels of maternal viremia, congenital t
275 intranasal inoculation with a low dose (200 PFU) resulted in a 10-fold decrease in vector growth in
276 ep-wise, Mg(2+)-dependent reconstitutions of Pfu RNase P with its catalytic RNA subunit and two inter
279 inal deletion mutant of Pyrococcus furiosus (Pfu) RPP29 that is defective in assembling with its bina
280 xperiments with an enzyme assembled with the Pfu RPR and five protein cofactors (POP5, RPP21, RPP29,
284 ant animals were vaccinated with 1.0 x 10(4) PFU s.c. at day 42 of gestation, when fetal sensitivity
286 assay was 2.8 x 10(2) plaque-forming units (PFU)/test and 1 x 10(3) PFU/test within 40 minutes for E
287 laque-forming units (PFU)/test and 1 x 10(3) PFU/test within 40 minutes for EBOV-Kikwit and EBOV-Mako
288 that received 20 million PFU or 100 million PFU than in the group that received 3 million PFU, as as
289 es in individuals vaccinated with 20 million PFU than in those vaccinated with 3 million or 100 milli
291 e vaccination with 20 million or 100 million PFU than with 3 million PFU, and these correlated strong
295 rthermophilic archaeon Pyrococcus furiosus ( Pfu) using conventional and paramagnetic NMR techniques.
296 HPAI H5N1 challenge: a dose as low as 1,000 PFU was sufficient to protect against lethal HPAI H5N1 c
299 a calculated 50% lethal dose (LD(50)) of 680 PFU, whereas there were no deaths of BALB/c mice at a 10
300 ental HEp-2 and PML(-/-) cells infected at 5 pfu wild-type virus per cell, but poorly in PML(-/-) cel
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