ライフサイエンスコーパス: pharyngitis

1 used to confirm group A streptococcus (GAS) pharyngitis.

2 nuated for colonization in a monkey model of pharyngitis.

3 used to diagnose group A streptococcal (GAS) pharyngitis.

4 ically carried between recurrent episodes of pharyngitis.

5 in 20 cynomolgus macaques with experimental pharyngitis.

6 llergic patients with Streptococcus pyogenes pharyngitis.

7 es or costs of diagnosis or treatment of GAS pharyngitis.

8 ar EL phenotype, 55% of whom had a preceding pharyngitis.

9 ract infections, such as the common cold and pharyngitis.

10 r gene was highly expressed during human GAS pharyngitis.

11 cimens taken from 18 pediatric patients with pharyngitis.

12 nce, China, suffered from scarlet fever-like pharyngitis.

13 represented in the pool of subclones causing pharyngitis.

14 agent in approximately 10% of adult cases of pharyngitis.

15 cs only if they have confirmed streptococcal pharyngitis.

16 racted separately for children with clinical pharyngitis.

17 rgency department with signs and symptoms of pharyngitis.

18 internal jugular vein secondary to bacterial pharyngitis.

19 sive disease than in strains from those with pharyngitis.

20 s were randomly collected from patients with pharyngitis.

21 development for prevention of streptococcal pharyngitis.

22 antibiotic treatment of acute streptococcal pharyngitis.

23 about this approach to diagnosing bacterial pharyngitis.

24 ated in cases of endemically occurring acute pharyngitis.

25 aryngitis clinically resembles streptococcal pharyngitis.

26 is used routinely to help diagnose and treat pharyngitis.

27 in adolescents and adults with suspected GAS pharyngitis.

28 ented with signs and symptoms similar to GAS pharyngitis.

29 at low risk for group A streptococcal (GAS) pharyngitis.

30 oropharynx of mice, and seldom caused human pharyngitis.

31 ity of its major regulatory target SpeB, and pharyngitis.

32 ediatric patients with group A streptococcal pharyngitis.

33 genetic subpopulation of strains that cause pharyngitis.

34 misclassifying 18, 446 patients without GAS pharyngitis.

35 ing a nonhuman primate model of experimental pharyngitis.

36 sive infection compared with strains causing pharyngitis.

37 ble diagnostic techniques for F. necrophorum pharyngitis.

38 gnosis and management of patients with acute pharyngitis.

39 n and culture for the detection of bacterial pharyngitis?

40 is, 9; Helicobacter pylori, 1; Streptococcal pharyngitis 1; and posttransplant lymphoma, 1).

41 , 1.60; 95% confidence interval, 1.51-1.70), pharyngitis (1.48; 1.15-1.89), aphonia (1.81; 1.18-2.80)

42 es for the management of adult patients with pharyngitis: 1) observation without testing or treatment

43 Of 451 children with pharyngitis, 107 (24%) had group A beta-haemolytic strep

44 rom patients with invasive disease (34%) and pharyngitis (21%) in the same period.

45 presented with serious complications of GAS pharyngitis: 29 (4.0%) had peritonsillar abscesses and 2

46 tibiotic prescriptions [95% CI, 41-54]), and pharyngitis (43 antibiotic prescriptions [95% CI, 38-49]

47 United States are for acute sinusitis, acute pharyngitis, acute bronchitis, and nonspecific upper res

48 Humans with documented GAS infections (pharyngitis, acute rheumatic fever, and severe invasive

49 al specimens from individuals suffering from pharyngitis aids in the management and selection of anti

50 es human diseases ranging from self-limiting pharyngitis (also known as strep throat) to severely inv

51 ial role for F. necrophorum as a pathogen of pharyngitis among young adults, but suggests that the pr

52 idemics, the sic gene was sequenced from 471 pharyngitis and 127 pyogenic and blood isolates recovere

53 m the throats of college students with acute pharyngitis and 5 strains isolated from patients with no

54 e results from 522 adult patients with acute pharyngitis and a positive ADT result; unexpectedly, 15%

55 pressed by some strains that cause impetigo, pharyngitis and acute glomerulonephritis.

56 but there were more instances of stomatitis/pharyngitis and hand-foot skin reaction in the continuou

57 esting, and office testing for streptococcal pharyngitis and Helicobacter pylori.

58 However, pharyngitis and impetigo are rarely observed prior to in

59 hat can manifest as a range of diseases from pharyngitis and impetigo to severe outcomes such as necr

60 The peak incidence for streptococcal pharyngitis and impetigo varies with season and locale,

61 ponsible for superficial infections, such as pharyngitis and impetigo, and severe invasive infections

62 e of most serotype M1 strains recovered from pharyngitis and invasive disease episodes in North Ameri

63 The pharyngitis and invasive groups were highly related to e

64 irulence gene profiles were identified among pharyngitis and invasive infection isolates.

65 subcutaneously with GAS and humans with GAS pharyngitis and invasive infections seroconverted to mos

66 Serotype M28 strains are a leading cause of pharyngitis and invasive infections, but little is known

67 ) is an important human pathogen that causes pharyngitis and invasive infections, including necrotizi

68 tion of the genetic relationship between GAS pharyngitis and invasive strains.

69 nd killing to cause human disease, including pharyngitis and necrotizing fasciitis (flesh-eating synd

70 streptococcus (GAS), the causative agent of pharyngitis and necrotizing fasciitis, secretes the pote

71 , and increase virulence in animal models of pharyngitis and necrotizing fasciitis.

72 more virulent in nonhuman primate models of pharyngitis and necrotizing fasciitis.

73 rapid, point-of-care testing method for GAS pharyngitis and obviate backup testing on negative resul

74 llance data into clinical guidelines for GAS pharyngitis and other communicable diseases should be co

75 developed clinical signs and symptoms of GAS pharyngitis and seroconverted to several GAS extracellul

76 t causes many types of infections, including pharyngitis and severe invasive diseases.

77 f infections in humans, from relatively mild pharyngitis and skin infections to life-threatening necr

78 Associations between GAS pharyngitis and specific food items were assessed among

79 overed from a single individual during acute pharyngitis and subsequent asymptomatic carriage.

80 visit-based prescribing rates decreased for pharyngitis and upper respiratory tract infection; howev

81 of a non-drug-related serious adverse event (pharyngitis) and 1 because of lack of treatment efficacy

82 and the periodic fever, aphthous stomatitis, pharyngitis, and adenopathy (PFAPA) syndrome.

83 Periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is a relative

84 rome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most c

85 PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) has been characteriz

86 ections, noninvasive soft tissue infections, pharyngitis, and rheumatic fever indicated that Slr is p

87 ections, noninvasive soft tissue infections, pharyngitis, and rheumatic fever indicated that these fo

88 scripts were detectable in patients with GAS pharyngitis, and the levels increased significantly duri

89 each) were identified in which otitis media, pharyngitis, and urinary tract infection (UTI) were trea

90 te otitis media; 6746, group A streptococcal pharyngitis; and 4234, acute sinusitis), 4307 (14%) were

91 ute otitis media; 705, group A streptococcal pharyngitis; and 667, acute sinusitis), 868 (35%) were p

92 opriate antibiotic use for adults with acute pharyngitis apply to immunocompetent adults without comp

93 Prompt diagnosis and treatment of GAS pharyngitis are cornerstones of the Rheumatic Fever Prev

94 GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause

95 Real-time regional data on GAS pharyngitis are generally not yet available to clinician

96 on the host mucosal surface and cause acute pharyngitis are poorly understood.

97 rheumatic fever after group A streptococcal pharyngitis are still poorly understood.

98 ndividual patients at very high risk for GAS pharyngitis as assessed by a clinical decision rule.

99 s), Fusobacterium necrophorum causes endemic pharyngitis at a rate similar to that of group A beta-he

100 diatric patients presenting with symptoms of pharyngitis at any of three Lahey Clinic acute care faci

101 s can be confounded by a lack of symptoms of pharyngitis at the time of presentation and end-organ dy

102 n the number of symptomatic individuals with pharyngitis beginning in mid-1999.

103 Antibiotic treatment of adult pharyngitis benefits only those patients with GABHS infe

104 ococcus (GAS) is a common causative agent of pharyngitis, but the role of GAS in otitis media is unde

105 Diagnosis of GAS pharyngitis by a rapid antigen detection test (RADT) or

106 However, these 2 emm types caused 69% of the pharyngitis cases identified during training and represe

107 occus (GAS) causes the majority of bacterial pharyngitis cases in humans and is prone to persistently

108 in Minnesota and for a significant number of pharyngitis cases that also occurred during the outbreak

109 GAS and humans with invasive infections and pharyngitis caused by GAS seroconverted to Shp, indicati

110 dy of molecular events contributing to acute pharyngitis caused by GAS.

111 ctiveness of various strategies for managing pharyngitis caused by group A beta-hemolytic streptococc

112 an alternative regimen for the treatment of pharyngitis caused by group A beta-hemolytic streptococc

113 d antimicrobial regimen for the treatment of pharyngitis caused by group A beta-hemolytic streptococc

114 roat swabs of each of 20 patients with acute pharyngitis caused by serotype M1 GAS.

115 Humans with GAS pharyngitis caused by serotype M6 strains had antibody a

116 isorder periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is unkno

117 dent population, and F. necrophorum-positive pharyngitis clinically resembles streptococcal pharyngit

118 f GAS in throat swabs taken from humans with pharyngitis confirmed the findings.

119 PEA is only rarely associated with TSS after pharyngitis, despite being highly associated with TSS af

120 A patient-driven approach to pharyngitis diagnosis that uses this new score could sav

121 ecrotizing fasciitis) and noninvasive (e.g., pharyngitis) diseases.

122 they choose to treat streptococcus-negative pharyngitis empirically.

123 r parent; both parent and child reported GAS pharyngitis episodes 3 weeks before the banquet.

124 ic research is needed on both F. necrophorum pharyngitis (especially clinical presentation) and the L

125 hargica (EL), a CNS disorder presenting with pharyngitis followed by sleep disorder, basal ganglia si

126 Clinically screen all adult patients with pharyngitis for the presence of the four Centor criteria

127 symptoms suggestive of group A streptococcal pharyngitis (for example, persistent fevers, anterior ce

128 olates recently recovered from patients with pharyngitis from 13 countries were characterized by emm

129 Many pharyngitis GAS strains circulate simultaneously.

130 Pharyngitis guidelines focus solely on group A beta-hemo

131 The frequency of antibiotic use for pharyngitis has greatly exceeded the prevalence of GABHS

132 The large majority of adults with acute pharyngitis have a self-limited illness, for which suppo

133 necrophorum causes at least 10% of cases of pharyngitis; however, few U.S. data exist.

134 roup A streptococcal diseases: uncomplicated pharyngitis, impetigo, and acute rheumatic fever.

135 ts for a variety of human diseases including pharyngitis, impetigo, toxic shock, and necrotizing fasc

136 elf-limiting diseases caused by GAS, such as pharyngitis, impose a significant economic burden on soc

137 are aphthous stomatitis in 70% of patients, pharyngitis in 72% of patients, and cervical adenitis in

138 Three outbreaks were studied: pharyngitis in a boarding school (serotype M5), cross-in

139 emm types causing asymptomatic carriage and pharyngitis in a closed population, we analyzed 675 isol

140 roup A beta-hemolytic streptococcal-positive pharyngitis in a student population, and F. necrophorum-

141 wabs of pediatric patients performed for GAS pharyngitis in a tertiary-care children's hospital netwo

142 ostic testing and treatment of suspected GAS pharyngitis in adults have very similar effectiveness an

143 expensive strategy at any prevalence of GAS pharyngitis in adults, although it may be reasonable for

144 the diagnosis of group A streptococcal (GAS) pharyngitis in adults.

145 and C/G streptococci as agents of bacterial pharyngitis in children.

146 Streptococcus pyogenes is a major cause of pharyngitis in humans and encodes several fibronectin-bi

147 has been implicated as a causative agent of pharyngitis in outbreak situations, but its role in ende

148 culture for the laboratory diagnosis of GAS pharyngitis in patients for whom testing is clinically i

149 s from an outbreak of erythromycin-resistant pharyngitis in Pittsburgh, PA, we found a correlation be

150 ic heart disease in children presenting with pharyngitis in urban primary care clinics in South Afric

151 Treating all children presenting with pharyngitis in urban primary care clinics in South Afric

152 pecific infections, i.e., skin infection and pharyngitis-induced acute rheumatic fever.

153 aseline and changed little for streptococcal pharyngitis (intervention, from 4.4% to 3.4%; control, f

154 Since acute pharyngitis is a frequently occurring infectious disease

155 o acute pharyngitis strains; thus, childhood pharyngitis is a major reservoir for strains with invasi

156 Acute pharyngitis is a nonspecific symptom that can result fro

157 Group A streptococcal (GAS) pharyngitis is a particularly important condition in are

158 Group A Streptococcus (GAS) pharyngitis is a very common condition causing significa

159 Adolescent and young adult pharyngitis is more complicated than previously consider

160 rred antibiotic for treatment of acute GABHS pharyngitis is penicillin, or erythromycin in a penicill

161 Streptococcal pharyngitis is still a major infectious disease seen in

162 Pharyngitis isolates represented 16 pulsed-field gel ele

163 absent from a genetically related subset of pharyngitis isolates.

164 , acute bronchitis (23%), otitis media (5%), pharyngitis, laryngitis, and tracheitis (11%), or more t

165 ost common DLTs were neutropenia, stomatitis/pharyngitis, myalgia, and arthralgia.

166 nfection for 22 (44%) of the children and by pharyngitis (no throat culture obtained) for 14 others (

167 orne outbreak of Group A Streptococcus (GAS) pharyngitis occurring among attendees of a high school d

168 Fusobacterium necrophorum-positive pharyngitis occurs more frequently than group A beta-hem

169 highly contagious purulent lymphadenitis and pharyngitis of members of the family Equidae.

170 ults were sensitive to the prevalence of GAS pharyngitis: OIA followed by culture was most effective

171 he routine primary evaluation of adults with pharyngitis or for confirmation of negative results on r

172 rum samples from patients with streptococcal pharyngitis or healthy control subjects.

173 d GABHS infection, 60 (42%) with symptoms of pharyngitis or upper respiratory infection (no throat cu

174 eases ranging in severity from uncomplicated pharyngitis (or strep throat) to life-threatening infect

175 e most common infections involve the throat (pharyngitis) or skin (impetigo); however, the factors th

176 plications (subglottic stenosis, laryngitis, pharyngitis, or cancer) can occur without esophagitis.

177 serotype M6 clone that was responsible for a pharyngitis outbreak in Pittsburgh, Pennsylvania, was co

178 Expanding the pharyngitis paradigm will have several important implica

179 In this foodborne outbreak of GAS pharyngitis, pasta was implicated as the vehicle.

180 on should be considered when clusters of GAS pharyngitis patients are encountered.

181 in vitro; however, analyses of sera from 155 pharyngitis patients revealed a strong correlation (P <

182 ver (ARF) and untreated scarlet fever and/or pharyngitis patients were reacted with streptococcal M p

183 a wide array of diseases in humans including pharyngitis, pneumonia, gastroenteritis, hemorrhagic cys

184 ive and most effective strategy when the GAS pharyngitis prevalence is 10%.

185 nt was the least effective strategy at a GAS pharyngitis prevalence of 10% (resulting in 0.41 lost qu

186 lowed by culture was most effective when GAS pharyngitis prevalence was greater than 20%.

187 Alleles shared among the pharyngitis, pyogenic, and blood samples were identified

188 d RLPP correlated with the likelihood of GAS pharyngitis (r(2) = 0.79; P < 0.001).

189 nd resolve without lasting effects; however, pharyngitis resulting from infection with Streptococcus

190 bronchitis," "respiratory tract infection," "pharyngitis," "rhinosinusitis," and "the common cold." H

191 consecutive patients with symptoms of acute pharyngitis seen in two outpatient clinics in a large su

192 atory toxicities included grade 4 stomatitis/pharyngitis, sepsis syndrome (one patient each), and gra

193 supernatant, and patients with streptococcal pharyngitis seroconverted to Sse, indicating that Sse wa

194 All patients with pharyngitis should be offered appropriate doses of analg

195 The diagnostic paradigm for adolescent pharyngitis should therefore be expanded to consider F.

196 s for presumptive treatment of streptococcal pharyngitis since bacterial culture and rapid diagnostic

197 iated with combination therapy were anxiety, pharyngitis, sinus congestion, and peripheral edema.

198 ratory tract encounters (acute otitis media, pharyngitis, sinusitis, presumed viral infection) after

199 he predicted amino acid sequences of the two pharyngitis strains were identical and were 88% homologo

200 e compared the genomes of 86 serotype M3 GAS pharyngitis strains with those of 215 invasive M3 strain

201 ionships between populations of invasive and pharyngitis strains.

202 pediatric GAS strains are identical to acute pharyngitis strains; thus, childhood pharyngitis is a ma

203 ts with group A beta-hemolytic streptococcal pharyngitis (strep throat) is an important task for clin

204 ignificance, causing infections ranging from pharyngitis (strep throat) to necrotizing fasciitis (fle

205 ng a diverse array of infections from simple pharyngitis ("strep throat") to invasive conditions, inc

206 s known about the genomes of strains causing pharyngitis (streptococcal "sore throat").

207 A STREPTOCOCCUS: (GAS) associated both with pharyngitis (streptococcal sore throat) and with invasiv

208 When testing for GAS pharyngitis, the throat remains the optimum site for sam

209 he new score estimated the likelihood of GAS pharyngitis to be less than 10% instead of having clinic

210 t causes infections ranging in severity from pharyngitis to life-threatening invasive disease, such a

211 of humans, causing a range of diseases from pharyngitis to necrotizing fasciitis.

212 tomatically and cause illnesses ranging from pharyngitis to necrotizing fasciitis.

213 at causes a multitude of human diseases from pharyngitis to severe infections such as toxic shock syn

214 tions ranging in severity from self-limiting pharyngitis to severe invasive diseases that are associa

215 ranging from superficial skin infections and pharyngitis to severe invasive infections such as necrot

216 es diseases ranging from mild, self-limiting pharyngitis to severe invasive infections.

217 uses a wide spectrum of disease ranging from pharyngitis to streptococcal toxic shock syndrome.

218 AS) causes many different diseases including pharyngitis, tonsillitis, impetigo, scarlet fever, strep

219 ARF sera and sera from uncomplicated pharyngitis (UNC) reacted with C repeat region peptides

220 ratory Improvement Amendments, streptococcal pharyngitis, urinalyses, office stool examination, and i

221 d to assess their use since the frequency of pharyngitis varies.

222 osest estimate of the true prevalence of GAS pharyngitis was 19.7% (71/361 samples).

223 (illumigene assay) for the diagnosis of GAS pharyngitis was compared with that of a RADT and standar

224 um samples from children with GAS-associated pharyngitis were assayed, and a strong immune response t

225 egarding treatment of streptococcal tonsillo-pharyngitis were revised.

226 a-hemolytic streptococcal scarlet fever-like pharyngitis were studied.

227 information about the local incidence of GAS pharyngitis, which is necessary to calculate the new sco

228 f adult patients with clinically significant pharyngitis who can benefit from treatment.

229 needs to identify those patients with acute pharyngitis who require specific antimicrobial therapy a

230 States each year and 8500 patients with GAS pharyngitis who would have received antibiotics would no

231 ported to be an important cause of bacterial pharyngitis with a prevalence as high as that of group A

232 the red flags for adolescent and young adult pharyngitis: worsening symptoms or neck swelling (especi