ライフサイエンスコーパス: phase advance

1 scle shortening in ankle extension, but with phase advance.

2 ng the LP along with the most rapid coherent phase advance.

3 -PACAP antibodies, augmented the Glu-induced phase advance.

4 of cell firing and a subsequent significant phase advance.

5 otoneurones themselves produce a significant phase advance.

6 of DRN GABAergic neurotransmission causes a phase advance.

7 in the SCN of females that experienced a 2-h phase advance.

8 ; the spindle discharge would then have been phase advanced.

9 during the 8-OH-DPAT perfusion abolished the phase advances.

10 did not suppress intra-SCN 8-OH-DPAT-induced phase advances.

11 8BA-AMP were able to block melatonin-induced phase advances.

12 bitory effects of WAY267464 on light-induced phase advances.

13 arly 75%, but had no effect on light-induced phase advances.

14 SCN prevented NPY- but not muscimol-induced phase advances.

15 roduced complete inhibition of light-induced phase advances.

16 light pulse partially blocked light-induced phase advances.

17 was able to achieve complete blockade of the phase advances.

18 e, but not muscimol, NMDA, or MK-801 induced phase advances.

19 60 min at circadian time 19) elicited large phase advances.

20 athways can mediate efficient adjustments to phase advances.

21 ntrained circadian cycles that resulted in a phase advance (3 x 21 h) and a phase delay (3 x 27 h) co

22 Interestingly, micromolar DA produces an LP phase advance accompanied by a decrease in LP burst dura

23 At baseline, a phase-advanced activity pattern and lower mesor distingu

24 The phase advance also enhanced calbindin and egr-1-ir, but

25 In summary, intrinsic excitatory neurons can phase advance and increase the frequency of antral slow

26 ger stimulation parameters (1.0-2.0 ms), EFS phase advanced and entrained slow waves in wild-type and

27 sic frequency of 4.4 cycles min(-1) and were phase advanced and entrained to a maximum of 6.3 cycles

28 he rest and activity rhythms of Bdr mice are phase advanced and fragmented under a light/dark cycle,

29 mine their ability to modulate light-induced phase advances and delays of circadian wheel running rhy

30 A(B) agonist, baclofen, induces both daytime phase advances and nighttime phase delays.

31 k genes Period1 and Period2 accompanied both phase advances and phase delays of the RPE-choroid clock

32 ized by the fourth cycle and could show both phase advances and phase delays, the latter dominated.

33 ptic chiasm stimulation inhibit serotonergic phase advances and that this inhibition involves both AM

34 y differentially contribute to light-induced phase advancing and phase delaying of the clock.

35 The results indicate that 8-OH-DPAT-induced phase-advances and delays are functionally distinct with

36 Daytime photic phase advances are mediated by a novel signaling pathway

37 individuals with a large and disabling sleep phase-advance are rare.

38 hat chronotherapies, including SDT and sleep phase advance, are dramatically effective suggests that

39 ex centres produced about the same amount of phase advance as the muscle spindles.

40 of phase shifts by CP154,526 was specific to phase advances as light-induced phase delays of the circ

41 phase delays at circadian time (CT) 13.5 and phase advances at CT 19.

42 (4) PER2 is ineffective at causing phase advances because it is not induced by light during

43 ated vibration still showed a delay-adjusted phase advance, but the value was less than that for simp

44 NPY-induced phase advances, but not inhibition, were blocked by the

45 magnitude of both 8-OH-DPAT- and VEH-induced phase advances, but not the magnitude of 8-OH-DPAT-induc

46 Because sensitivity to phase advance by light-GLU-activated GC-cGMP-PKG occurs

47 tion was still rhythmic but with peak levels phase advanced by 4.5-6 h, whereas the rhythm in monocyt

48 n activity rhythms in Syrian hamsters can be phase advanced by a variety of stimuli including microin

49 RF(1) receptor antagonist, DMP695, inhibited phase advances by approximately 40% at a dose of 10 mg/k

50 Melatonin inhibited phase advances by the 5-HT agonist, (+)DPAT, and this in

51 Conversely, melatonin was unable to block phase advances by the cyclic AMP analog, 8BA-cAMP.

52 f circadian rhythm of locomotor activity was phase-advanced by 1 h in control but not in GTG-treated

53 Calorie restriction phase-advanced by 80 min the locomotor activity rhythm i

54 e monophosphate (cAMP) analog, 8-bromo-cAMP, phase advanced circadian neuronal rhythms in both aged a

55 CT 10) to C3H/HeN mice kept in constant dark phase advanced circadian rhythms of wheel running activi

56 he first study to demonstrate that melatonin phase advances circadian rhythms by activation of a memb

57 ents to repeated stimuli, contrast-dependent phase advance, contrast saturation, and cross-orientatio

58 Such phase advance counteracts the tendency to tremor introdu

59 quency was reduced to below 6 Hz the central phase advance decreased.

60 rhythmic elbow movement showed a systematic phase advance during the discrete shoulder shift, simila

61 ce occurs between waves undergoing different phase advances during propagation, we show that the vect

62 The GABA(A) agonist, muscimol, induces phase advances during the mid-subjective day, while the

63 ptors, was also effective in attenuating the phase advancing effect of arousal at CT 10.

64 of mTOR during the late night augmented the phase-advancing effect of light.

65 4 h after the onset of the light pulse; the phase advancing effects of light were completely blocked

66 The phase advancing effects of light were not altered in tho

67 The phase-advancing effects of light at circadian time (CT)

68 onist to block the phase-delaying and/or the phase-advancing effects of light in animals kept in cons

69 did not potentiate either phase-delaying or phase-advancing effects of light on the rat activity rhy

70 ify mutants (groom-of-PDF; gop) that display phase-advanced evening activity and poor free-running rh

71 longed excitation in the vastus medialis and phase-advanced excitation (both early initiation and ear

72 b transitions (e.g. semimembranosus) showing phase-advanced excitation.

73 BW373U86 phase advanced hamster wheel running activity rhythms by

74 quired for light- or glutamate (GLU)-induced phase advance in late night.

75 very closely in the case of TA and with some phase advance in the case of MG.

76 f metformin leads to mPer2 degradation and a phase advance in the circadian expression pattern of clo

77 e human stretch reflex is known to produce a phase advance in the EMG reflexly evoked by sinusoidal s

78 propylamino)tetralin (8-OH-DPAT), to cause a phase advance in the firing pattern of SCN neurons was a

79 chanism for Per1 elevation and light-induced phase advance in the suprachiasmatic nucleus (SCN), a pr

80 and plasma corticosterone are both markedly phase advanced in Bdr mice.

81 ht pulse at CT 19 responsible for initiating phase advances in circadian activity rhythms can be modu

82 ly and significantly inhibited light-induced phase advances in hamster circadian activity rhythms lat

83 for their ability to modulate light-induced phase advances in hamster circadian activity rhythms.

84 ively doubles the magnitude of light-induced phase advances in hamster circadian wheel running rhythm

85 t potentiated light-induced phase delays and phase advances in response to a 30 min light pulse, resp

86 constant darkness was characterized by large phase advances in response to light exposure during the

87 Aging significantly inhibited (P<0.01) the phase advances in running-wheel rhythms induced by 8-OH-

88 during the mid-subjective day induced 40-min phase advances in the locomotor activity rhythm of wild-

89 ein synthesis is necessary for light-induced phase advances in the mammalian circadian clock, and ind

90 Glutamate (GLU)-induced phase advances in the rat SCN were blocked by antisense

91 dent induction of bmal1 gene expression, and phase advances in the suprachiasmatic nucleus clock.

92 M in the late night is accompanied by stable phase advances in the temporal regulation of the PER and

93 CRE-decoy ODN also blocked light-induced phase advances in vivo.

94 jective day, a time when dark pulses cause a phase-advance in circadian rhythm of locomotor activity.

95 hm of FTD patients was highly fragmented and phase-advanced in comparison with controls and apparentl

96 at CT 10 but the drug was without effect on phase advances induced by exposure to light.

97 shifts in vitro, but does not block in vitro phase advances induced by muscimol.

98 Phase advances induced by SCN 8-OH-DPAT perfusion were s

99 G advance cannot be attributed solely to the phase advance introduced by the muscle spindles, and sho

100 This was taken to be the phase advance introduced by the spindles, very slightly

101 mediating DRN 5-HT(7) receptor induction of phase advances involves decreased glutamatergic neurotra

102 2 phase, indicating that the ABP1-induced G2 phase advance is an indirect effect of cell expansion.

103 itory activity of 8-OH-DPAT on light-induced phase advances is not apparent when injected just 3 h af

104 at the proximal poly(A) site, but as growth phase advances, it extends to the distal site.

105 to travel over space in terms of consistent phase advances, it is unknown how this phenomenon relate

106 agonist BMY 7378 from 1 to 7 h after a short phase advancing light pulse at CT 19 in hamsters to asse

107 ntralateral light information as part of the phase-advancing light entrainment pathway to the circadi

108 We compared cultures subjected to a phase-advancing light pulse (LP) to cultures maintained

109 pounds are injected 30 min to 1 h prior to a phase-advancing light pulse, and it is not known if thes

110 susceptible to modification for 6 h after a phase-advancing light pulse.

111 In contrast, phase-advancing light pulses did not affect mTim levels.

112 light/dark and sleep/wake/meal schedule was phase-advanced (made earlier) by 9 hours differed in Eur

113 Thus the central phase advance mechanisms behave like a high-pass filter.

114 The phase advance might increase to above 90 deg, showing th

115 However, phase-advanced misalignment caused flattening of the cor

116 When coadministered, PACAP blocked the phase advance normally induced by Glu during late night.

117 phase at the core body temperature minimum, phase advances occurred when the light stimulus was cent

118 The same conditions produced a phase advance of expression for the GmTOC1-like, GmLUX-l

119 ion is sufficient to cause a non-photic-like phase advance of PER2::LUC rhythms on a Per2(Luc+/-) bac

120 d with men, women demonstrated a significant phase advance of the CBT but not melatonin rhythms, as w

121 light-stimulated GLU neurotransmission into phase advance of the circadian clock.

122 hotic social and photic cues following a 6-h phase advance of the LD cycle; and (iv) the circadian pe

123 t rates of circadian rhythms following a 6-h phase advance of the light-dark (LD) cycle; (ii) photic

124 ainment rates to photic cues following a 6-h phase advance of the light-dark (LD) cycle; (iii) reentr

125 These changes, and the associated internal phase advance of the propensity to awaken from sleep, ap

126 both stretching and modulated vibration, the phase advance of the response elicited by a fixed sinuso

127 P in vivo also potentiated the light-induced phase advance of the rhythm of hamster wheel-running act

128 e we describe three kindreds with a profound phase advance of the sleep-wake, melatonin and temperatu

129 ntially provides a major contribution to the phase advance of the stretch reflex.

130 - 0.3 hr were obtained at CT 14, and maximum phase advances of 3.5 +/- 0.2 hr were obtained at CT 20.

131 MT2 (Mel1b) melatonin receptor in mediating phase advances of circadian activity rhythms by melatoni

132 y contributing to the absence of NPY-induced phase advances of PER2::LUC rhythms in organotypic SCN c

133 t significantly attenuated the light-induced phase advances of the activity rhythm.

134 ion for the antidepressant response to light-phase advances of the circadian clock-by measuring the o

135 and death after four consecutive weekly 6-h phase advances of the light/dark schedule, with 89% mort

136 Morning light produced phase advances of the melatonin rhythm, while evening li

137 short-acting benzodiazepine that results in phase advances of the wheel running activity in hamsters

138 WAY267464 (10 mg/kg) inhibited light induced phase advances of wheel running rhythms by 55%, but had

139 Calorie restriction can induce phase-advances of daily rhythms in rodents exposed to li

140 Phase-advances of locomotor activity rhythm that can nor

141 Dopamine induced phase-advances of the PER2::LUC bioluminescence rhythm d

142 eatment with the NK1 antagonist, significant phase-advances of wheel-running activity rhythm were fou

143 Circadian misalignment, either phase advanced or phase delayed, did not result in any c

144 ain effect of circadian misalignment, either phase advanced or phase delayed, is a concomitant distur

145 These data suggest that for Ca2+ to induce phase advances or delays, light-induced signaling from R

146 re or after the onset of wheel-running, they phase-advance or delay, respectively, the timing of the

147 ous period lengths; tau) are associated with phase-advanced or delayed sleep-wake rhythms, respective

148 e either excited by membrane depolarization (phase advanced) or exhibit slowed membrane repolarizatio

149 Disruption of the receptor is accompanied by phase-advanced oscillations of the core clock protein PE

150 was tested with sinusoidal inputs and gave a phase advance over a wide range of frequencies.

151 Based on these results, in situ gas-phase advanced oxidation is a viable control strategy fo

152 Gas-phase advanced oxidation is able to remove compounds tha

153 iates and byproducts produced during aqueous-phase advanced oxidation processes (AOPs) for various or

154 Aqueous phase advanced oxidation processes (AOPs) produce hydrox

155 byproducts that are produced during aqueous-phase advanced oxidation processes (AOPs).

156 In this article, gas-phase advanced oxidation, a new method for pollution con

157 cuculline also potentiated 8-OH-DPAT-induced phase advances (P<0.05).

158 The resulting PRC has a phase advance portion peaking about 5 h before the dim l

159 smission within the SCN is necessary for the phase advances produced by NPY or muscimol.

160 reas rhythmicity in other tissues was either phase advanced relative to the light cycle or absent.

161 xial length in constant darkness is slightly phase-advanced relative to eyes in L/D and thus is simil

162 ive contralateral nerves, which were in turn phase-advanced relative to pre-block controls.

163 frequencies above 10 Hz the adjusted central phase advance remained approximately constant.

164 afternoon/evening to induce phase delays or phase advances, respectively, without causing sleepiness

165 nd the putative 5-HT7 receptor, impaired the phase-advancing response to arousal at CT 10 but the dru

166 Also, phase-advance shifts induced by novel wheel access at mi

167 ion, morning light (which causes a circadian phase advance) should be more antidepressant than evenin

168 maximum at the carrier frequency, while the phase advance showed a maximum at 0.8 of the carrier.

169 l trials, SCN 5-HT release associated with a phase-advancing sleep deprivation stimulus at midday was

170 rk-release experiments showing additivity in phase advances suggest that the arrthymicity caused by Z

171 finding that bicuculline blocks NPY-induced phase advances, suggest that NPY requires sodium-depende

172 th large effects have been found in familial phase advance syndrome and in subjects with short sleep

173 5-CT induced phase advances tended to decrease with aging, but this e

174 complete inhibition of the baclofen-induced phase-advances than the phase-delays.

175 KC via phorbol 12-myristate 13-acetate (PMA) phase advanced the clock at all phases tested.

176 Splanchnicectomy reduced and phase advanced the peak of both the corticosterone and A

177 Microdrop application of NPY to the SCN phase advanced the time of peak firing rate.

178 bition by chelerythrine chloride application phase advances the in vitro circadian rhythm during the

179 Conversely, NPY only phase advances the neuronal activity rhythm when applied

180 Morning light phase-advanced the dim-light melatonin onset and was mor

181 ated with TRZ (5 mg/kg) at ZT6 significantly phase advanced their clock.

182 efore projected activity onset (i.e., CT 10) phase-advanced their free-running circadian rhythm of wh

183 or abnormalities at least up to the subacute phase, advances this cortical hemorrhage model as a plat

184 n a dose-dependent manner at phase delay and phase advance time points.

185 Phase advances to 8-OH-DPAT in the slice were attenuated

186 ery 23.5 h for 7 days caused large composite phase-advances to the wheel-running rhythm, the latter p

187 to morning light increased with the size of phase advances up to 2.7 hours (r = 0.44) regardless of

188 Hz (gain 0.27, phase error 6 degrees), and a phase advanced VOR during low frequency rotations at 0.0

189 reas, after bright light supplementation the phase advance was 8.1 h (SEM 0.7 h).

190 An 8-hour phase advance was found both for Rev-erbalpha and Bmal1

191 ermates, GIRK2 knock-out (KO) mice failed to phase advance wheel-running behavior in response to 3 d

192 5-HT induced 2-3 h phase advances when applied during subjective day, while

193 agonists, such that NPY can block 5-HTergic phase advances, while 5-HT agonists do not prevent NPY-i

194 The adjusted phase advance with modulated vibration was taken to repr

195 with an approximately frequency-independent phase advance with respect to the input.

196 f the 'carrier frequency' in determining the phase advance with sinusoidal inputs.