ライフサイエンスコーパス: phase separation

1 lation transitions can occur with or without phase separation.

2 ents in such organelles can assemble through phase separation.

3 gnetic responsiveness of magnetite for solid-phase separation.

4 ross the loop domain, plausibly facilitating phase separation.

5 embranes than lipid mixtures with microscale phase separation.

6 t by using RNA competition to regulate local phase separation.

7 as attributed to pair-breaking, disorder and phase separation.

8 dely used mechanism to promote intracellular phase separation.

9 s and the much longer polyanionic RNAs drove phase separation.

10 ecular monodispersity for ultrasmall ordered phase separation.

11 y lowering the critical temperature (Tc) for phase separation.

12 n terms of clustering driven by the onset of phase separation.

13 roliferation of dislocations plus electronic phase separation.

14 granules that assemble through liquid-liquid phase separation.

15 of chromosomes through a process similar to phase separation.

16 ce area of the lipid membrane resulting from phase separation.

17 compartments assemble through liquid-liquid phase separation.

18 re known physiological targets of Whi3 drive phase separation.

19 m the nucleoplasm by concentration-dependent phase separation.

20 P granule assembly in vivo through promoting phase separation.

21 muL of methanol was added to facilitate the phase separation.

22 are driven by chemical instability based on phase separation.

23 ircumvented by eliminating postequilibration phase separation.

24 - and microstructural alterations during the phase separation.

25 ctivity might impact classical liquid-liquid phase separation.

26 3 domain, and this effect appears to promote phase separation.

27 in interactions analogous to a liquid-liquid phase separation.

28 in the adhesion protein nephrin, leading to phase separation.

29 py-driven solid solution and enthalpy-driven phase separation.

30 the microscopic processes that occur during phase separation.

31 ps, however, under illumination they undergo phase separation.

32 all microscopic processes that occur during phase separation.

33 nse liquid precursor phase via liquid-liquid phase separation.

34 at galectin-3 can also undergo liquid-liquid phase separation.

35 single-chain conformational compactness and phase separation.

36 of linear multivalent proteins is driven by phase separation.

37 (InAlAs) nanocomposites by using spontaneous phase separation.

38 heir role in the brush's temperature-induced phase separation.

39 dent of clathrin, caveolin, actin, and lipid phase separation.

40 reduction of the length scale of electronic phase separations.

41 tive role for arginine-rich domains in these phase separations.

42 For phase separation, 1.5g NaCl and 4g anhydrous MgSO4 were

43 on of heterochromatin domains is mediated by phase separation, a phenomenon that gives rise to divers

44 mperature, and, on the other hand, preserves phase separation above the transition temperature.

45 ra-toxin treatment, but found this nanoscale phase separation absent in native cells.

46 uantitatively understand how the fluid-fluid phase separation affects the crystal nucleation, we eval

47 micelles (LCM) in dilute solution, underwent phase separation after heating at 55 degrees C for 10 mi

48 equence have been shown to undergo a similar phase separation, allowing formation of biomaterials tha

49 The associated phase separation allows measuring the partitioning of sm

50 Mott transition, revealing the importance of phase separation and calling for further investigation i

51 We investigate phase separation and communication across leaflets in te

52 ndings demonstrate that careful control over phase separation and crystallization can yield solution-

53 tellurium oxide with silica glass increases phase separation and crystallization tendency when mixed

54 mic charged biological membranes, we studied phase separation and domain formation in GUVs of ternary

55 eneralized to other systems with large scale phase separation and has potential as a powerful method

56 sociation, we demonstrate rapid baseline gas-phase separation and identification of tails involving m

57 nd that this disorder is retained both after phase separation and in elastic materials.

58 The interplay between phase separation and kinetic arrest is important in supr

59 quid droplets in vitro through liquid-liquid phase separation and liquid-like non-membrane-bound stru

60 in interactions and ultimately the degree of phase separation and morphology evolution.

61 Phase separation and packing models of the bottlebrushes

62 branes prepared via solvent transfer-induced phase separation and photopolymerization have exceptiona

63 new information about the mechanism of lipid phase separation and potentially about the physical basi

64 ver deposition conditions allows for tunable phase separation and preferential PEDOT backbone alignme

65 eads to new modes of packing, self-assembly, phase separation and relaxation of colloidal liquids; ho

66 emulsions showed the greatest resistance to phase separation and resulted in stable emulsions.

67 f LAF-1 is necessary and sufficient for both phase separation and RNA-protein interactions.

68 Through the spontaneous phase separation and self-assembly growth, two phases fo

69 With this combined gas-phase separation and subsequent fragmentation, we could

70 chloride excimer laser-induced melt-mediated phase separation and surface reconstruction of single-cr

71 However, the role of protein disorder in phase separation and the macromolecular organization wit

72 implying a connection between the structural phase separation and the shape of the superconducting do

73 itive processing to promote crystallization, phase separation, and efficient light harvesting.

74 nclude that heterochromatic domains form via phase separation, and mature into a structure that inclu

75 s for understanding LC domain self-assembly, phase separation, and regulation by post-translational m

76 ent-vortex structure lives on the verge of a phase separation, and single out the very constituents r

77 nally, to affect bilayer thickness and lipid phase separation, and subsequently measured single-integ

78 n situ analysis of the hygroscopic behavior, phase separation, and surface composition of collected a

79 mitochondrial matrix in live cells occurs by phase separation, and that solid-phase stores provide a

80 ate interplay among materials crystallinity, phase separation, and the relative positions of the lowe

81 ore sophisticated optical objects, to direct phase separation, and to facilitate colloidal assemblies

82 disordered proteins to achieve liquid-liquid phase separation, and we demonstrated that galectin-3 ca

83 Any growing lengthscale using this spinodal phase separation approach must first traverse the UV and

84 r deciphering the sequence dependence of IDP phase separation are discussed.

85 single barb scattering data implies that the phase separation arrest mechanism is rapid and also dist

86 e, ethanol, and gamma-valerolactone) exhibit phase separation at cellulose surface and whether this a

87 Micellar phase separation at cloud point temperature of non-ionic

88 constantly within such organelles affect the phase separation behavior of the constituent macromolecu

89 Phase separation behavior of thermoresponsive poly(N-iso

90 ets of experiments support the hypothesis of phase separation being the driving process behind compar

91 charge of alpha-lac below pH 5.5 and led to phase separation below pH 5.

92 ton, on the one hand, suppresses large-scale phase separation below the phase transition temperature,

93 scaling of rhos with Tc(3.2) as well as the phase separation between magnetism and superconductivity

94 Under these conditions, we observed dramatic phase separation between the densest clusters of RNAPs a

95 nding ureidopyrimidinone (UPy) motif undergo phase separation between their aromatic end groups and d

96 phase is slow enough to induce viscoelastic phase separation, but fast enough to prevent immediate v

97 eless organelles originate via liquid-liquid phase separation, but how their distinct structural and

98 halide perovskites can be stabilized against phase separation by deliberately engineering carrier dif

99 Phosphorylation-driven phase separation can be promoted or reversed by specific

100 These results demonstrate that protein phase separation can create a distinct physical and bioc

101 These results suggest that phase separation can give rise to multilayered liquids t

102 membrane properties such as the fluidity and phase separation capability of giant plasma membrane-der

103 aneless compartments thought to be formed by phase separations caused by low-affinity, multivalent in

104 Phase separation confined on nanoscale, together with de

105 The macrocyclization protocol employed a phase separation/continuous flow manifold whose advantag

106 The phase separation/continuous flow strategy afforded simil

107 A phase separation/continuous flow strategy employing an o

108 ticles with droplets formed by liquid-liquid phase separation could provide a physical mechanism for

109 A polymer-aggregation-phase-separation-crystallization mechanism for the evolu

110 tagenesis reveals that the driving force for phase separation depends on the overall amino acid compo

111 d bilayers, suggesting that complete lateral phase separation did not occur.

112 Liquid-liquid phase separation, driven by collective interactions amon

113 ndense at one end of the embryo by localized phase separation, driven by gradients of polarity protei

114 Dynamical phase separation during a solid-solid phase transition p

115 ere we present a new concept for controlling phase separation during solution printing using an all-p

116 Importantly, it is the phase separation during the two-phase reaction of the Li

117 methylsiloxanes relies upon the dominance of phase separation effects over directional end group aggr

118 ervation and modelling that incorporation of phase-separation effects into activation thermodynamics

119 f the morphology of the nanoscale structural phase separation enables determination of the associated

120 The presence of a solvent can lead to phase separation, evaporation and leakage on deformation

121 ixed gel structures of AX/BG1, indicative of phase separation events.

122 he oncogenic EWS-FLI1 fusion protein enables phase-separation events, which inappropriately recruit c

123 Locust bean gum showed the greatest phase separation, followed by XG.

124 this platform makes use of gravity to enable phase separation for analysis and is 48 times faster and

125 tly occurring microscopic and/or macroscopic phase separation for the formation of self-supporting mo

126 ld, these constructs undergo light-activated phase separation, forming spatiotemporally definable liq

127 y protocol, we follow the entire kinetics of phase separation, from homogeneous phase to different ar

128 believed to lead to particle aggregation and phase separation; hence, stability improvement can be ac

129 Self-assembled nanostructures with periodic phase separation hold great promise for creating two- an

130 rdomain order disparity and the stability of phase separation holds for a spectrum of different pertu

131 Remarkably, ABs form not by liquid-to-liquid phase separation, implicated in RNA-seeded granule assem

132 r simulations are carried out to investigate phase separation in a granular gas under vibration.

133 ue, we provide direct evidence for nanoscale phase separation in a model membrane, which may provide

134 hree-sublayer vertical phase morphology with phase separation in agglomerated domains.

135 Phase separation in biological membranes plays an import

136 ry has been developed to model liquid-liquid phase separation in bulk systems.

137 oth spatial and temporal resolution to study phase separation in complex materials.

138 by the prokaryotic tubulin homolog, FtsZ, on phase separation in freestanding lipid membranes.

139 The observation of phase separation in giant plasma membrane-derived vesicl

140 Liquid-liquid phase separation in giant unilamellar vesicles (GUVs) le

141 ighly stable heterocomplexes that influences phase separation in liquid-like organelles.

142 luctuations and used it to measure stages of phase separation in model lipid bilayer membranes.

143 mbine these techniques to detect and predict phase separation in monolayers that mix uniformly or exp

144 t results on the inhibition of liquid-liquid phase separation in nanoscale particles and studies that

145 ular binding domains can induce gelation and phase separation in several cytosolic and membrane-assoc

146 atially controlled by the degree of spinodal phase separation in the corresponding region of the feat

147 Phase separation in the cytoplasm is emerging as a major

148 gnetoelectric coupling, which is enhanced by phase separation in the manganite.

149 At room temperature, phase separation in the membrane was detected for GM1 fr

150 n-prone/prion-like character, disrupting FUS phase separation in the presence of RNA or salt and redu

151 her T N in the parent, it promotes nanoscale phase separation in the superconductor resulting in lowe

152 lly tune its biophysical properties and Pab1 phase separation in vitro and in vivo.

153 n cells that an HP1alpha mutant incapable of phase separation in vitro forms smaller and fewer nuclea

154 Low-complexity proteins undergo phase separation in vitro, forming hydrogels or liquid d

155 on in vivo, and suppresses RNA-induced MEG-3 phase separation in vitro.

156 ts the emergence of thermodynamic electronic phase separation in which metallic ferromagnetic islands

157 ontrast, immiscible binary mixture undergo a phase separation in which the clusters transition separa

158 ressure gradients on-chip for driving liquid phase separations in submicrometer deep channels.

159 Here, we discuss how phase separation, in which a component of one of the two

160 t dynamics that are characteristic of liquid phase-separation, including sensitivity to the disruptio

161 crosslinking acrylate and urethane, wherein phase separation induces the spontaneous, directed forma

162 l embryos, our system uses cadherin-mediated phase separation, inspired by the known phenomenon of ca

163 Only Cs- and Rb-NAT reveal a phase separation into a dense form (P2 phase) under pres

164 the silicon carbide surface, resulting in a phase separation into a disordered carbon layer with par

165 ming solid RNA/protein aggregates or through phase separation into a liquid RNA/protein phase.

166 ls, with progressive confinement, we observe phase separation into a micrometer-size isotropic drople

167 py and energy-dispersive X-ray spectroscopy, phase separation into Fe- and Cr-rich phases was observe

168 enced by nanoleakage in the hybrid layer and phase separation into hydrophobic- and hydrophilic-rich

169 This complex, multiscale phase separation invites the development of theories of

170 ns with specific compositions, implying that phase separation is a robust mechanism for creating spat

171 Microscopic phase separation is detectable by fluorescent labeling,

172 In STRIPS, phase separation is induced by solvent extraction from a

173 spheric aerosols with internal liquid-liquid phase separation is inferred.

174 Phase separation is promoted by low salt concentrations

175 Instead, phase separation is promoted by one or more regions of h

176 solvent are floated on the mixture, and the phase separation is simply achieved.

177 However, the extent of lo/ld phase separation is sparse, mainly due to the ability of

178 model suggests that the driving force behind phase separation is the bandgap reduction of iodide-rich

179 Our results indicate that, although phase separation is the main mode of recruitment for fou

180 Intracellular liquid-liquid phase separation is thought to drive the formation of co

181 Liquid-liquid phase separation is ubiquitous in suspensions of nanopar

182 Non-solvent induced phase separation is widely employed to prepare porous po

183 m-10 microm is established by regulating the phase separation kinetics.

184 suggest that consideration of liquid-liquid phase separation, leading to complete or partial engulfi

185 Phase separation leads to limited availability of the cr

186 s of these organs were enriched by detergent phase separation, lectin affinity chromatography, and SD

187 physical properties to undergo liquid-liquid phase separation (LLPS) in cells.

188 -related RBP hnRNPA1 undergoes liquid-liquid phase separation (LLPS) into protein-rich droplets media

189 Liquid-liquid phase separation (LLPS) is thought to contribute to the

190 Liquid-liquid phase separation (LLPS) of RNA-binding proteins plays an

191 esulting from crowding-induced liquid/liquid phase separation (LLPS) on the dynamic spatial organizat

192 ecent evidence suggests that a liquid-liquid phase separation (LLPS) process may drive their formatio

193 go phase transitions including liquid-liquid phase separation (LLPS) while responding to changes in t

194 dency of the system to undergo liquid-liquid phase separation (LLPS).

195 Perturbations that alter liquid-liquid phase separations (LLPS) driven by intrinsically disorde

196 uence determinants of the driving forces for phase separation may be generally important to Nck funct

197 While liquid-liquid phase separation may drive RNP granule assembly, the mec

198 y: In particular, the picket fence effect on phase separation may explain why micrometer-scale membra

199 eye disease and the strategy of ELP-mediated phase separation may have applicability to other disease

200 he polyethylene glycol-induced liquid-liquid phase separation measurements and the phenomenological e

201 is rapid and also distinct from the spinodal phase separation mechanism i.e. it is not gelation or in

202 Understanding the phase separation mechanism of solid-state binary compoun

203 ot appear to fundamentally alter the passive phase separation mechanism.

204 demonstrate that the domains arise through a phase separation mechanism.

205 he polyethylene glycol-induced liquid-liquid phase separation method.

206 aterials with tailored branch functionality, phase separation, microdomain spacing, and mechanical pr

207 We propose that a phase separation model explains established and recently

208 Here, we examine the phase separation model for the formation of membraneless

209 However, a main challenge to such phase separation models is that the initial assembly, or

210 mentally observed suppression of large-scale phase separation much below the transition temperatures

211 In gelation driven by phase separation multivalent proteins and their ligands

212 against the effect of freeze-thaw cycles (no phase separation observed).

213 Phase separation occurs during evaporation, and in the p

214 Herein we show that phase separation occurs through self-similar cycles of m

215 howing that large-scale assembly and protein phase separation occurs within a variety of signaling co

216 expansions similarly undergo LLPS and induce phase separation of a large set of proteins involved in

217 Our approach utilizes phase separation of a polymer solution during the prefor

218 Segregation and phase separation of aliovalent dopants on perovskite oxi

219 n previously demonstrated to be critical for phase separation of ALS-linked stress granule proteins.

220 simulations exhibited unknotted chromosomes, phase separation of chromatin types, and a tendency for

221 Viscoelastic phase separation of colloidal suspensions can be interru

222 e of Phe and Arg interactions in driving the phase separation of Ddx4, while the salt dependence of b

223 We propose that phase separation of disordered proteins containing weakl

224 ure and function and afford insight into the phase separation of disordered proteins.

225 These compartments assemble via the phase separation of disordered regions of proteins in re

226 tracellular membraneless organelles form via phase separation of intrinsically disordered proteins (I

227 Liquid-liquid phase separation of intrinsically disordered proteins (I

228 -less organelle formed through liquid-liquid phase separation of its components from the surrounding

229 ted access to RNA, combined with RNA-induced phase separation of key scaffolding proteins, may be a g

230 Furthermore, we show that GR and PR altered phase separation of LCD-containing proteins, insinuating

231 f eukaryotic cells can be controlled through phase separation of lipids, proteins, and nucleic acids.

232 ents for the effect to arise are the spatial phase separation of metallic and insulating regions duri

233 In addition, FAIMS enables gas-phase separation of molecular classes, for example, lipi

234 to the driving forces for self-assembly and phase separation of multivalent proteins.

235 en the first two SH3 domains of Nck enhances phase separation of Nck/N-WASP/nephrin assemblies.

236 ization, as structural features required for phase separation of NPM1 with other nucleolar components

237 hese materials are formed by the associative phase separation of oppositely charged polyelectrolytes

238 Polymerization and phase separation of proteins containing low-complexity (

239 d in biomaterials development, liquid-liquid phase separation of proteins remains poorly understood.

240 mechanism of nucleolar localization involves phase separation of proteins within the nucleolus.

241 Both the redistribution and phase separation of radiogenic Pb in this manner can com

242 le cations is to suppress the enrichment and phase separation of Sr while reducing the concentration

243 Binding of SynGAP to PSD-95 induces phase separation of the complex, forming highly concentr

244 maging technique without any pretreatment or phase separation of the fluid samples.

245 pite large molecular weight differences, gas-phase separation of the four compounds in the DMS drift

246 e system deviates from a solid solution, and phase separation of the GeS1-xSex (5-20 mum) precipitate

247 t P granule asymmetry depends on RNA-induced phase separation of the granule scaffold MEG-3.

248 In human cells, RNA foci form by phase separation of the repeat-containing RNA and can be

249 s organelles that appear to assemble through phase separation of their molecular components.

250 Phase separation of these molecules likely plays an impo

251 Reversed-phase separations of nucleosides, nucleotides, and amino

252 Liquid-phase separations of similarly sized organic molecules u

253 Despite finding varied degrees of phase-separation of organosolv on cellulose surfaces, ph

254 F) calculations to detect and predict ligand phase separation on Ag nanoparticles.

255 is study shows that the STO surface exhibits phase separation once the 2DES is formed and relates thi

256 show the second domain, suggesting that the phase separation only happens in nontensioned (flat) mem

257 Here, we demonstrate that charge-mediated phase separation, or complex coacervation, of RNAs with

258 etwork structure different from the original phase separation pattern.

259 known for its large length-scale electronic phase separation phenomena.

260 on in Ca3(Ru(1-x)Ti(x))2O7 happens through a phase separation process in the 2-5% Ti range, whereas s

261 ocoagulation (EC) has long been considered a phase separation process, well suited for industrial was

262 branes for filtration is predominated by the phase-separation process.

263 h similar pore size prepared by conventional phase-separation processes.

264 Mutations that impede phase separation reduce organism fitness during prolonge

265 nt order that provides a basis for nanoscale phase separation remains a key open question, because ex

266 Gelation driven by phase separation requires lower protein concentrations,

267 go a phase transition in which liquid-liquid phase separation results in the formation of a particle

268 of amine (such as HEP) is able to ensure the phase separation, satisfactory absorption efficiency, ef

269 rganelles that may assemble by intracellular phase separation, similar to the condensation of water v

270 Phase separation, size, and structure of alpha-lac/CMD-b

271 endritic PEG cosolvents were employed in the phase separation strategy for the first time and shown t

272 ric bijels based on solvent-transfer-induced phase separation (STRIPS) is demonstrated.

273 ed by aqueous mixing followed by fluid-fluid phase separation, such as coacervation.

274 s to the minimization of behavior leading to phase separation, such as two-phase and oxygen evolution

275 Ion mobility (IM) is a gas-phase separation technique that is used to determine the

276 Ion mobility spectrometry (IMS) is a gas phase separation technique, which relies on differences

277 characterisation of the systems that undergo phase separation, the mechanisms by which this phase tra

278 sidues or phosphorylating the IDR raised the phase separation threshold above that of the unmodified

279 f the polySH3-polyPRM system, decreasing the phase separation threshold concentration by 8-fold.

280 ccess to RNA, thus locally suppressing MEG-3 phase separation to drive P granule asymmetry.

281 hermal drawing process with polymer solution phase separation to fabricate porous multimaterial fiber

282 ry low temperature that is commensurate with phase separation to form a Cr-rich phase with a nanoscal

283 he SynGAP/PSD-95 complex is critical for the phase separation to occur and for proper activity-depend

284 as a physiological stress sensor, exploiting phase separation to precisely mark stress onset, a broad

285 by using a template-free temperature-induced phase separation (TTPS).

286 However, degradable upper critical phase separation (UCST) block copolymers that would allo

287 tonitrile as the extractant and acetonitrile phase separation under high-salt conditions.

288 ortunately, mixed halide perovskites undergo phase separation under illumination.

289 hobic, disordered, and undergo liquid-liquid phase separation upon self-assembly.

290 , a disordered protein, drives intracellular phase separation via complex coacervation, whereby the n

291 Type VI secretion system (T6SS) precipitates phase separation via the 'Model A' universality class of

292 To probe how polarity proteins regulate phase separation, we combined biochemistry and theoretic

293 Shift in charge and the critical pH of phase separation were both sensitive to the alpha-lac to

294 ecting the complex formation, extraction and phase separation were optimized using factorial designs.

295 pon low-complexity regions (LCRs) or RNA for phase separation, whereas Pab1's LCR is not required for

296 They exhibit a reversible phase separation whereby samples remain soluble below a

297 the chemical landscape associated with lipid phase separations, which leads to more sophisticated app

298 PT, resulting in a broad region of intrinsic phase separation, while the ordered magnetic moment reta

299 with MeCN:citrate buffer:NaHCO3 followed by phase separation with the addition of MgSO4:NaCl.

300 -domains, such as the nucleolus, result from phase separations within the nucleus, which are driven b