ライフサイエンスコーパス: phenotypically

1 l bacteria that are difficult to distinguish phenotypically.

2 n poorly characterized transcriptionally and phenotypically.

3 lls to hemogenic endothelium are not defined phenotypically.

4 e form of tooth agenesis, is genetically and phenotypically a heterogeneous condition.

5 hat ILCs distribute among various organs and phenotypically adapt to the tissue environment they inva

6 Of the 77 carriers, 71 (92%) were phenotypically affected and showed cardiac conduction di

7 lly represent three genetically distinct yet phenotypically ambiguous taxa with various degrees of pa

8 s that anxiety is a multifactorial construct phenotypically and aetiologically, highlighting the impo

9 ntially responsive cell populations, defined phenotypically and by BCR characteristics.

10 (TGCTs) share germline ancestry but diverge phenotypically and clinically as seminoma (SE) and nonse

11 itatively by vaccination, were characterized phenotypically and compared using double hierarchical cl

12 olepis behave as a single functional species phenotypically and ecologically well differentiated from

13 tors to give rise to CD8(+) T cells that are phenotypically and functionally analogous to those found

14 In this study, we phenotypically and functionally characterized murine kid

15 he transcription factors Nfil3 and T-bet but phenotypically and functionally distinct from adipose ma

16 Human NK cells can be classified into phenotypically and functionally distinct subsets based o

17 Acute myeloid leukemia (AML) manifests as phenotypically and functionally diverse cells, often wit

18 Phenotypically and functionally diverse regulatory T (Tr

19 Airway memory CD4(+) T cells differed phenotypically and functionally from lung-derived cells

20 Eosinophils are phenotypically and functionally heterogeneous.

21 4(+) T cells from CD4-cre Runx1 cKO mice are phenotypically and functionally immature as shown by dec

22 The resulting EMT cells phenotypically and functionally resemble pericytes and a

23 These monocytes were similar, phenotypically and functionally, to the myeloid-derived

24 Human pDCs are distinguished from mouse pDCs phenotypically and functionally.

25 heterogeneous and complex phenomenon that is phenotypically and genetically associated with affective

26 ia and Archaea) are naturally organized into phenotypically and genetically cohesive units comparable

27 icing a mobile hunter-gatherer lifestyle are phenotypically and genetically diverged from other anato

28 Multiple pterygium syndrome (MPS) is a phenotypically and genetically heterogeneous group of ra

29 Congenital myopathies are phenotypically and genetically heterogeneous.

30 These disorders are phenotypically and genetically heterogeneous.

31 se results suggest that trail making is both phenotypically and genetically strongly associated with

32 eeds, Yorkshire and Landrace, are considered phenotypically and genetically very similar, but distinc

33 l abilities constitute a single factor, both phenotypically and genetically, even after controlling f

34 demic subjects correlated substantially both phenotypically and genetically, even after controlling f

35 ted with general cognitive ability (g), both phenotypically and genetically.

36 his highly informative neurogenetic syndrome phenotypically and genomically.

37 unsolved cases that were biased toward more phenotypically and genotypically complicated cases.

38 ultiple coexisting lineages diversified both phenotypically and genotypically.

39 ependent transgenic lines were characterized phenotypically and genotypically.

40 cal isolates that were selected to represent phenotypically and genotypically/molecularly susceptible

41 by enforced expression of N-Myc, to generate phenotypically and molecularly accurate tumors that clos

42 We identify two phenotypically and molecularly distinct GBM subtypes gov

43 Osteogenesis imperfecta is a phenotypically and molecularly heterogeneous group of in

44 indings highlight cancer's ability to evolve phenotypically and suggest a phenotype-targeted treatmen

45 recent common ancestors and are more similar phenotypically, and are more likely to hybridise, than s

46 MCs were numerically, phenotypically, and functionally compared between germ-f

47 NK-cell reconstitution was quantitatively, phenotypically, and functionally superior compared with

48 tional regulatory hubs in diseases as varied phenotypically as chronic obstructive pulmonary disease

49 This direct component of Hrd3 is phenotypically as important as Hrd1 in the native HRD co

50 stor are expected to diverge genetically and phenotypically as they adapt to different local environm

51 Loss of WASP was phenotypically associated with increased GATA3 expressio

52 ng to their engulfment by neutrophils, while phenotypically avirulent pathogens remained in the intes

53 recipients at high risk of SCC and analyzed phenotypically by flow cytometry.

54 We generate and phenotypically characterize 29 mutant strains with delet

55 henotyping Consortium effort to generate and phenotypically characterize 5,000 knockout mouse lines,

56 e report the use of a proteomics approach to phenotypically characterize hPSC-derived PPs and disting

57 We use this approach to phenotypically characterize the loss of SNF4Agamma, enco

58 omechanism of this disease, we generated and phenotypically characterized a novel knock-in humanized

59 tic spirochete that has been molecularly and phenotypically characterized and provisionally named "Br

60 nsplant recipients) grafts were isolated and phenotypically characterized as to subsets and Toll-like

61 Children with ASD may be phenotypically characterized based upon their immune pro

62 Patients were phenotypically characterized on clinical data as rapidly

63 monstrate the utility of this collection, we phenotypically characterized six T-DNA lines with insert

64 erall diversity of the reference set, and we phenotypically characterized the training set for biomas

65 tic mutation in a single gene yet produces a phenotypically complex disorder with a range of neurolog

66 that when highly purified, anatomically and phenotypically confirmed club cells are seeded in 3-dime

67 tiviral vector, results in the generation of phenotypically corrected HSPCs capable of repopulating a

68 ntly, a marked increase in the proportion of phenotypically corrected, patient-derived hematopoietic

69 less of AMD affection status, and moderately phenotypically correlated with AMD severity.

70 Fruits from different phenotypically cultivars were sampled for firmness, tota

71 eposits in human atherosclerotic plaques are phenotypically defective being unable to resorb calcific

72 However, in these early reports, Tregs were phenotypically defined as CD4(+) CD25(+) or CD4(+) CD25(

73 r unselected for a specific subpopulation or phenotypically defined as undifferentiated and highly cl

74 nonuclear cells could be tracked back to the phenotypically defined hematopoietic stem cell (HSC) com

75 rmal megakaryocytes and increased numbers of phenotypically defined hematopoietic stem cells (HSCs).

76 ubsets and suggest, for the first time, that phenotypically defined human NK cell subsets may differe

77 myeloid leukemia (AML) with genetically and phenotypically defined LSCs.

78 a statistical method for determining whether phenotypically defined subgroups of disease cases repres

79 We found that phenotypically different 3LL and 4T1 tumors shared the s

80 pe MC and connective tissue-type MC released phenotypically different EV populations depending on the

81 ation of parietal regions were found between phenotypically different forms of LD.

82 ocks present in these cells are dominant and phenotypically different from each other.

83 ity (carboxylated vs. pyrrolidonated) by two phenotypically different human endothelial cell types (t

84 ethods for single cell isolation struggle to phenotypically differentiate specific cells in a heterog

85 nockout studies suggest that most miRNAs are phenotypically dispensable.

86 tional CD8(+) T cells to peripheral tissues, phenotypically displaying hallmarks of residency and yie

87 Mother cells inheriting old poles are phenotypically distinct and display increased drug efflu

88 We have studied whether melanoma cells are phenotypically distinct and hierarchically organized acc

89 sion, we show that TP53 mutations identify a phenotypically distinct and highly aggressive form of MC

90 y of two potent antiproliferative leads with phenotypically distinct anticancer mode of actions.

91 The intratumor microenvironment generates phenotypically distinct but interconvertible malignant c

92 frequently characterized by genomically and phenotypically distinct cancer cell subpopulations withi

93 g of the roles of IL-21 in the generation of phenotypically distinct CD4 and CD8 T cell populations a

94 symbiotic model of collective invasion where phenotypically distinct cell types cooperate to promote

95 t prostate cancer (mCRPC) patients to define phenotypically distinct cell types.

96 Bacterial persisters are rare, phenotypically distinct cells that survive exposure to m

97 spontaneous model of EMT which involves four phenotypically distinct clones derived from a primary tu

98 ined endocytic properties, we identified two phenotypically distinct clusters of NSCLCs.

99 he following behaviours: (1) They consist of phenotypically distinct cores of cells that move forward

100 al covering of the heart, is mediated by two phenotypically distinct epicardial cell subpopulations.

101 rently prevalent wave 3 AET strains are both phenotypically distinct from and more virulent than many

102 1 confers resistance to a late block that is phenotypically distinct from blocks previously described

103 derived cells, and dendritic cells that were phenotypically distinct from cell populations found in b

104 e multiciliated cells revealed that they are phenotypically distinct from neighboring MIWI2-negative

105 pathophysiology, one that is genetically and phenotypically distinct from other children with IBD.

106 an lungs (Siglec-8+CD62L+IL-3Rlo cells) were phenotypically distinct from the iEos isolated from the

107 The human isolates were phenotypically distinct from the type strain isolated fr

108 are communities of sessile microbes that are phenotypically distinct from their genetically identical

109 We report that circulating TFR are phenotypically distinct from tonsil-derived TFR in human

110 nografts and the ability to differentiate to phenotypically distinct hepatic cells.

111 ic, and antimicrobial characteristics of six phenotypically distinct human clinical isolates that mos

112 astrel from around the world conferring four phenotypically distinct levels of resistance.

113 formation of effector cells (TE) as well as phenotypically distinct memory cells that are retained o

114 asily appreciated in cutaneous disorders, as phenotypically distinct mutant cells often give rise to

115 genitor cells, which ultimately gave rise to phenotypically distinct neutrophils that readily left th

116 ,000 Mb of metagenomic DNA cloned from three phenotypically distinct patients for effectors that acti

117 ntactin-associated protein, can be linked to phenotypically distinct peripheral neuropathies.

118 elop a high-resolution method of identifying phenotypically distinct progenitor cell subpopulations v

119 pplying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) withi

120 Genetic crosses of phenotypically distinct strains of the human malaria par

121 ndothelial cells (HSECs), a functionally and phenotypically distinct subpopulation of endothelial cel

122 ablish that the vascular adventitia contains phenotypically distinct subpopulations of progenitor cel

123 geneity, which describes the genetically and phenotypically distinct subpopulations of tumor cells pr

124 embryo-derived Nkx2-5(+) CPCs represent two phenotypically distinct subpopulations that can become e

125 s a DNA methyltransferase and results in two phenotypically distinct subpopulations, ON and OFF.

126 IL-10DCs consist of two phenotypically distinct subpopulations: CD83(high)CCR7(+

127 These findings identify a genetically and phenotypically distinct subset of human ALL that critica

128 geneity and relationships within and between phenotypically distinct subsets of cTregs and eTregs are

129 ajor cause of human disease, often producing phenotypically distinct syndromes.

130 istent with the idea that CD151 could mark a phenotypically distinct T cell subset, it was not unifor

131 phages, these newly differentiated cells are phenotypically distinct, and likely play a unique role i

132 e data indicate that transmitted viruses are phenotypically distinct, and that increased IFN resistan

133 lung cancer cells, that these genotypes are phenotypically distinct.

134 iding in separated network neighborhoods are phenotypically distinct.

135 ed with which identical sister cells tend to phenotypically diverge from each other has so far remain

136 Gene flow between phenotypically divergent populations can disrupt local a

137 Many partially migratory species show phenotypically divergent populations in terms of migrato

138 lden-winged/blue-winged warbler complex, two phenotypically divergent warblers that are indistinguish

139 Thus, our findings elucidate how phenotypically diverse cells perceive ECM alignment at t

140 mprised of morphologically, genetically, and phenotypically diverse cells.

141 beta-diversity by promoting the assembly of phenotypically diverse communities.

142 homogeneous subtype of this genetically and phenotypically diverse disorder.

143 ectopic mineralization disorders represent a phenotypically diverse group of conditions characterized

144 Importance: Stargardt disease is a phenotypically diverse macular dystrophy caused by the a

145 the development of demyelinating lesions are phenotypically diverse or arise from a single lineage.

146 onized by exome analysis of large cohorts of phenotypically diverse parent-offspring trios.

147 However, by helping to restore phenotypically diverse pollinator communities, small-sca

148 reatment regimens [9-12] and the analysis of phenotypically diverse populations adapting under fluctu

149 igin, cancer stem cells (CSCs) must generate phenotypically diverse progenies including mature CSCs t

150 rassicaceae family, is a morphologically and phenotypically diverse species exhibiting metal toleranc

151 ion, we present a new ex vivo model in which phenotypically diverse stem and non-stem glioblastoma ce

152 Four representative but molecularly and phenotypically diverse strains were used for in vitro an

153 been difficult to discriminate between them phenotypically, efforts to pinpoint the developmental or

154 lthough previous studies of cell populations phenotypically enriched in HPCs and HSCs show expression

155 from the two hosts, and the viruses appeared phenotypically equivalent in most assays we conducted.

156 When phenotypically evaluated by NA inhibition, the dual H275

157 isability (ID) disorders are genetically and phenotypically extremely heterogeneous.

158 nsin II-induced AAA formation and rupture in phenotypically female mice.

159 x determination and sex reversal, such as XY phenotypically female patients in humans.

160 of the model species, P. tricornutum, differ phenotypically from each other after having been grown f

161 ly supporting their young age, have diverged phenotypically from oceanic ancestors to nearly the same

162 n of CD19-CAR-modified CD8(+) TSCM that were phenotypically, functionally, and transcriptomically equ

163 Here, we have shown that naive monocytes are phenotypically heterogeneous and contain an NR4A1- and F

164 CL/P is phenotypically heterogeneous and has a complex etiology

165 We have shown that TRAV1-2(-) T cells are phenotypically heterogeneous and largely distinct from T

166 Finally, moDCs are phenotypically heterogeneous and therefore necessitate t

167 Sarcomas are rare, phenotypically heterogeneous cancers that disproportiona

168 s been challenging in prior studies in which phenotypically heterogeneous CAR-T cell products were pr

169 ar noncompaction (LVNC) is a genetically and phenotypically heterogeneous disease and, although incre

170 h amelogenesis imperfecta, a genetically and phenotypically heterogeneous group of inherited conditio

171 derived subclones from a patient can produce phenotypically heterogeneous self-renewing progenies in

172 rs a large collection of developmentally and phenotypically heterogeneous subtypes.

173 Circulating tumor cells (CTCs) are phenotypically heterogeneous, and in vitro analysis of t

174 MM is genetically and phenotypically heterogeneous, so targeting of >1 antigen

175 (18)F-Fluoride PET/CT highlights culprit and phenotypically high-risk carotid plaque.

176 cell tolerance arose from the elimination of phenotypically hostile NK cells that express an allospec

177 Phenotypically, however, the degree to which plants enga

178 ng of pairs of sibling PDX tumors grown from phenotypically identical CD271(-) or CD271(+) cells show

179 lp in performing comparison and alignment of phenotypically identical cell populations across differe

180 Phenotypically important part of this variation often co

181 to develop lineage-specific and potentially phenotypically important variation.

182 nces, and which, therefore, are likely to be phenotypically important.

183 nomic diversity need not always be reflected phenotypically, in contrast to the suggested situation i

184 sistance (QR) refers to a resistance that is phenotypically incomplete and is based on the joined eff

185 ons during clonal growth to rapidly generate phenotypically independent individuals.

186 u-Myc-driven lymphoma in Hsp70(-/-) mice was phenotypically indistinguishable from that in WT Emu-Myc

187 tyrosine, and methionine substitutions were phenotypically indistinguishable from the wild type.

188 Single fps1 and fps2 knockout mutants are phenotypically indistinguishable from wild-type plants,

189 h clusters of functionally related genes are phenotypically informative: Different patients possessin

190 Phenotypically, knockdown of TFII-I alters the cellular

191 The PSC macrophages are phenotypically like AMs both functionally and by ligand

192 The results suggest that behavior that looks phenotypically like excessive self-control does not corr

193 imated risks of GVHD-related outcomes in HLA-phenotypically matched unrelated recipients were low, re

194 In HLA-A, B, C, DRB1, DQA1, DQB1, DPA1, DPB1-phenotypically matched unrelated recipients, the average

195 dom Forest for neovascularization identified phenotypically meaningful nonsynonymous SNPs in the ICP4

196 e the implications of social interactions in phenotypically mixed populations at the individual level

197 econciled if these cases of CUP constitute a phenotypically modified primary lacking tissue identific

198 egs generated after another 5 to 6 days were phenotypically, molecularly, and functionally characteri

199 increased Ras-Raf-MEK signaling occurred in phenotypically more aggressive liver cancers overexpress

200 ders, suggesting that it is useful to create phenotypically more homogenous groups when searching for

201 der, and schizophrenia (SCZ) is increased in phenotypically more homogenous MDD patients identified b

202 A phenotypically more inclusive approach may help to achie

203 asts (overall difference, P = .008) and were phenotypically more similar to screen-detected breast ca

204 ived T cells were CD45RO(neg)CCR7(+)CD95(+), phenotypically most similar to TSCM, and possessed a mem

205 e we describe a previously unknown subset of phenotypically naive human CD8(+) T cells that rapidly s

206 R signaling for their survival and function, phenotypically naive Tr cells occupying secondary lympho

207 pproximately half of the native protein) are phenotypically near-normal; and those expressing a minim

208 variants are "passenger" mutations that are phenotypically neutral and thus not targetable.

209 Phenotypically nongroupable strains accounted for 88% of

210 otypic analyses showed that atg12 plants are phenotypically normal and fertile when grown under nutri

211 Interspecies gene swaps result in phenotypically normal divisions with the S. japonicus li

212 Further, a phenotypically normal ductal outgrowth resulted from a s

213 ribed in the same ejaculate of an infertile, phenotypically normal male patient.

214 The pups appear phenotypically normal until 13 days of age, after which

215 eterozygous for the p.Pro76Leu mutation were phenotypically normal while homozygotes demonstrated a d

216 6PD heterozygous females who are reported as phenotypically normal with current point of care tests.

217 yte-specific inactivation of BiP, which were phenotypically normal without evidence of neuropathology

218 CXCR7(DeltaEND/DeltaEND) mice appeared phenotypically normal, although these animals exhibited

219 Sirolimus-derived Tregs were phenotypically normal, anergic to allostimulation, and s

220 is currently unclear how the tissue remains phenotypically normal, despite the presence of these mut

221 xpectedly, elmo2-knockout zebrafish appeared phenotypically normal, suggesting that there might be hu

222 nic PTEN mutations, the FOXP3(+) T cells are phenotypically normal.

223 Phenotypically, Npas2 deficiency induced severe steatosi

224 orphism detection performance that explained phenotypically observed antibiotic resistance.

225 t the serotype, regardless of whether it was phenotypically or genotypically determined, was a weak p

226 Shp2 mutant mice are phenotypically osteopetrotic, featuring a marked increas

227 a suitable surface marker distinguishing the phenotypically overlapping pre- from the post-Aire MHCII

228 unrelated probands with a new syndrome that phenotypically overlaps Cornelia de Lange syndrome (CdLS

229 Phenotypically, patients with AGS and SLE share many sim

230 tical conditions: they are highly correlated phenotypically, perfectly correlated genetically (indica

231 We analyze the fixation probability of the phenotypically plastic allele as a function of phenotypi

232 We find that the fate of a phenotypically plastic allele depends fundamentally on t

233 testinal MPs, de novo differentiated MPs are phenotypically pro-inflammatory and produce robust amoun

234 nchymal-epithelial transitions (EMT/MET) and phenotypically recapitulate the metastatic cascade.

235 ry and autonomic neuropathies are a group of phenotypically related diseases caused by monogenic muta

236 Advanced informatics tools can identify phenotypically relevant disease models in research and d

237 Furthermore, using phenotypically relevant epigenomes to weight the GWAS si

238 ggesting that GATA expression levels drive a phenotypically relevant source of epigenomic plasticity.

239 Instead, it is phenotypically reminiscent of the infertility of olt mic

240 e novo assemblies of nine geographically and phenotypically representative pigs from Eurasia.

241 press 9 latency-associated EBV proteins, and phenotypically resemble antigen-activated B-blasts.

242 id syndromes are rare genetic disorders that phenotypically resemble natural aging.

243 lated with vaccine-specific serum IgG; these phenotypically resembled GCTfh, and were clonally relate

244 te containing a truncated E3 homologue, MPXV phenotypically resembles a wild-type (wt) VACV rather th

245 ata, we found that the latent HIV-1 promoter phenotypically resembles endogenous long terminal repeat

246 SC (Eo-MDSC) in S. aureus-infected mice that phenotypically resembles eosinophils.

247 reases cystogenesis 10-fold, producing cysts phenotypically resembling PKD that expand massively to 1

248 hat Mycobacterium tuberculosis, likely to be phenotypically resistant to antibiotics, are present in

249 It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a majo

250 error, to analyze primary cultured isolates phenotypically resistant to rifampin, fluoroquinolones,

251 E6/E7 repression, and that E6/E7 inhibition phenotypically results in cellular senescence.

252 A phenotypically rich data set provides a psychiatrically

253 to five sublineages that are genetically and phenotypically separated from wild strains and originate

254 Shigella flexneri can be phenotypically serotyped using antisera raised to type-s

255 de and facilitates recovery of recessive and phenotypically silent conditional mutations.

256 ugh type 1 and type 2 viruses are considered phenotypically similar at several levels, there is a dis

257 d to more rapidly generate genotypically and phenotypically similar cancers.

258 ducted via an exome sequencing dataset of 18 phenotypically similar case subjects and 1,917 control s

259 This work demonstrates that the phenotypically similar cell population still exhibits a

260 the idea that convergent evolution generates phenotypically similar cells in distinct genetic branche

261 populations, resulting in the generation of phenotypically similar cells with distinct origins and d

262 with wild-type transthyretin amyloidosis, a phenotypically similar condition, present with more adva

263 Phenotypically similar DCs accumulated at primary and se

264 unique species with genetically diverse yet phenotypically similar genomovars (I, II, and III).

265 This finding raises the possibility that a phenotypically similar nuclear export of large RNAs is c

266 A phenotypically similar population of CD4(+) Foxp3+, CD40

267 diverse genetic mechanisms that can produce phenotypically similar responses to various soil water d

268 and is more powerful to distinguish between phenotypically similar subpopulations.

269 ese findings suggest that the SR mesocarp is phenotypically similar to a lignifying endocarp.

270 ns with the HTLV-1 CA NTD produced particles phenotypically similar to HTLV-1 immature particles, hig

271 These myeloid cells are phenotypically similar to inducible nitric oxide synthas

272 onocyte differentiation into Mo-DCs that was phenotypically similar to MR1(-/-) mice.

273 completely replaced over time; Mf1 and Mf2, phenotypically similar to peripheral blood monocytes (PB

274 he human mast cells in NSG-SGM3 BLT mice are phenotypically similar to primary human mast cells and e

275 but not the remaining virus-encoded GPCRs is phenotypically similar to that of wild-type latent infec

276 WHIRLY1-1 (W1-1), W1-7, and W1-9 plants were phenotypically similar to the wild type but produced few

277 signaling, develop multiple tumors that are phenotypically similar to those of BWS patients.

278 Phenotypically similar, but CD90(-)CD49f(-) cells (MPPs)

279 etal skewing, as is the case in other known, phenotypically similar, mutants.

280 genotypically, the three genetic groups are phenotypically similar.

281 The leader cell cultures are phenotypically stable and highly invasive in contrast to

282 Furthermore, PHH spheroids remained phenotypically stable and retained morphology, viability

283 (CD1) and rLCMV/NP(CD2) were genetically and phenotypically stable during serial passages in FDA vacc

284 an exception, being similarly heritable but phenotypically substantially uncorrelated both with g an

285 ssion of the pluripotency gene Klf4 in these phenotypically switched perivascular cells promoted a le

286 Samples from 510 of these birds were phenotypically tested for ESBL production using the comb

287 Phenotypically, the F1 hybrids show remarkable heterosis

288 Phenotypically, the new T/F virus strains exhibited a ra

289 Phenotypically, the round-shaped DCs were CD86 positive.

290 Phenotypically, these T cells are enriched in CD8(+) and

291 ial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a re

292 replication of the bacteria and render them phenotypically tolerant to most available drugs.

293 rculating IL-21-producing CD4(+) T cells are phenotypically, transcriptionally, and functionally simi

294 Although phenotypically unique, the main population relies on NFI

295 and glucocorticoid-induced TNFR exon 5, were phenotypically unstable, and exhibited diminished suppre

296 The isolates were studied phenotypically using standard growth conditions.

297 have no identified mutation in FLNA and are phenotypically very similar to individuals with FLNA mut

298 absence of antibodies against the pathogen, phenotypically virulent C. rodentium, accumulated and in

299 h concentrations of imipenem that select for phenotypically wild-type mutants, the active-site residu

300 Detection of carbapenemases was performed phenotypically, with confirmation by polymerase chain re