ライフサイエンスコーパス: phenyl

1 e is significantly destabilizing relative to phenyl.

2 introduced at the ortho positions of the TPP phenyls.

3 o installed in the para positions of the TPP phenyls.

4 compounds, (S)-(2-fluoro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyrimidin-2-yl)-6-methyl-1,4, 6,7-tet

5 moiety wherein the corresponding expected 3'-phenyl-1'H-spiro[indene-2,2'-quinazoline]-1,3,4'(3'H)-tr

6 esulting from chronic exposure to 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine or intranigral inocul

7 s were rendered parkinsonian with n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and dyskinetic

8 prevents neurodegeneration in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of PD.

9 Although the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model is

10 lthy macaques and 8 macaques with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced bilater

11 gic systems in seven asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-intoxicated mon

12 odel of Parkinson's disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

13 sonism by administration of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and quantified the sp

14 ignaling reduces neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a parkinsonism-induci

15 I receptor significantly reduces 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic n

16 with the mitochondrial neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

17 ent of the phenotype in the MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridinen) model of PD.

18 ydro-6H-furo[2,3-c]pyrrol-6-ones (10), and 1-phenyl-1,2-dihydro-3H-benzo[4,5]thieno[2,3-c]pyrrol-3-on

19 conversion of 2-hydroxyacetophenone to (S)-1-phenyl-1,2-ethanediol with low efficiency.

20 Anancomeric 5-phenyl-1,3-dioxanes provide a unique opportunity to stud

21 uorophenyl)diazene and 1-(perfluorophenyl)-3-phenyl-1,4-dihydrobenzo[e][1,2,4]triazinyl are also pres

22 on of an amine side product, N,N'-dimethyl-1-phenyl-1-(o-tolyl)methanamine.

23 between temocillin MICs and efflux rate of N-phenyl-1-naphthylamine (MexAB-OprM fluorescent substrate

24 tructure and conformational preferences of 1-phenyl-1-X-1-silacyclohexanes C5H10Si(Ph,X) (X = F (3),

25 -chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamid e), and lacking in Trpv1(

26 )-7-methyl-5-(1-methyl-5-(4-(trifluoromethyl)phenyl)-1H-p yrazol-4-yl)imidazo[1,5-f][1,2,4]triazine,

27 o the identification of ketoamide-based 2-(3-phenyl-1H-pyrazol-1-yl)nicotinamides as potent and rever

28 dentified 6-(2-methoxyphenyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3 H,6 H)-dione (o

29 golimod (FTY720) or 2-amino-4-(4-(heptyloxy) phenyl)-2-methylbutan-1-ol (AAL(S) ), or inhibiting prot

30 al goal to solve synthetic problems toward 5-phenyl-2,2'-bipyridine (Phbpy), we found that this react

31 ynthesis of the antidepressant agent (+/-)-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine.

32 acetone with the formation of 3,3-dimethyl-6-phenyl-2,3-dihydro-1,2,4-triazin-4-oxide (7'), which als

33 enzamide (ChemBridge ID5217941)] sharing a N-phenyl-2,4-dichlorobenzamide scaffold, which were select

34 ic studies suggest that in the presence of N-phenyl-2-(di-tert-butylphosphino)pyrrole as the ligand,

35 ation of a donor modified at C-2 with a (1S)-phenyl-2-(phenylsulfanyl)ethyl chiral auxiliary.

36 in equilibrium with its open-chain isomer 2-phenyl-2-(propan-2-ylidenehydrazono)acetaldehyde oxime (

37 Methoxycarbonyl-1-phenyl-2-cyclopropylmethyl based derivatives cis-(+)-1a

38 osylceramide synthase inhibitors (dl-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol and phosp

39 alyzed B-H insertion reactions with methyl 2-phenyl-2-diazoacetate.

40 cal pairs from DMDO hydroxylation of trans-1-phenyl-2-ethylcyclopropane measured by Newcomb.

41 wo cyclic azomethine imines, 7-methyl- and 7-phenyl-2-oxo-Delta(7)-hexahydropyrazolo[1,5-a]pyridin-8-

42 ,2-dimethylpropanal, ethyl methanoate, and 2-phenyl-2-oxoethanal as the negative-ion-mode mobile-phas

43 fragmentation of sulfide radical cations (2-phenyl-2-propanol and diaryl disulfides).

44 ther highly toxic chemical compounds (e.g. 1-phenyl-2-thiourea, PTU) or pigmentation mutant strains (

45 ntified two compounds [N-[4-(anilinocarbonyl)phenyl]-2,4-dichlorobenzamide (ChemBridge, San Diego, CA

46 omethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3- fluoro-4-hydroxypyrrolidin-1-yl)methanone 28,

47 ronicotinamid o)butanamido)butanamido)methyl)phenyl)-3-(naphthalen-2-ylmethyl)-1,4,12-trioxo-2, 5,11,

48 GS-458967, 6-(4-(Trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridi

49 sted compounds, the (R,S)-4-(6,7-dihydroxy-1-phenyl-3,4-tetrahydroisoquinoline-1H-2-carbonyl)benzenes

50 tion in equilibrium with its cyclic isomer 6-phenyl-3-(4-methylphenyl)-2,3-dihydro-1,2,4-triazin-4-ox

51 ction can proceed through the formation of 6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-4(3H)-ol (4-OH), w

52 (HTS) followed by optimization provided a 4-phenyl-3-aryl-sulfoquinoline lead compound with the mini

53 imination using ammonia in the presence of 1-phenyl-3-methyl-5-pyrazolone (PMP) to prevent alditol pe

54 hydro-1,2,4-triazine-based nitrone, namely 6-phenyl-3-pyridin-2-yl-2,3-dihydro-1,2,4-triazin-4-oxide

55 xy-1-phenylsilacyclohexane 2 and 3-hydroxy-3-phenyl-3-silatetrahydropyran 3 could not be frozen at 10

56 or 1-methoxy-1-phenylsilacyclohexane 1 and 3-phenyl-3-silatetrahydropyran 4 the conformational equili

57 gical evaluation, and mechanism of action of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonat

58 PAIB-SOs are N-dealkylated into cytotoxic phenyl 4-(2-oxo-3-imidazolidin-1-yl)benzenesulfonates (P

59 hloro-4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)-4-((4,5-dihydro-1H-im idazol-2-yl)amino)benzamid

60 chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluorome thyl)benzenesulfonamide (1, T2384

61 As a result, 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridi

62 we have prioritized the chemical series of N-phenyl-4H-thieno[3, 2-b]pyrrole-5-carboxamide for which

63 005 [(E)-3-(4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimida zolidin-1-yl)-2

64 ounds 2-75 [4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin -1-yl)-2

65 Two compounds, namely N-phenyl-5-(2-(p-tolylamino)thiazol-4-yl)isoxazole-3-carbo

66 ds employed, L(azine) = 4-(4-methylphenyl)-3-phenyl-5-(azine)-1,2,4-triazole, where azine = pyridine,

67 -labeled N,N-diethyl-2-(2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-alpha]pyrimi dine-3-yl)

68 -[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-p yrazole-4-carboxylic ac

69 most potent hit compound, N-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carboxamide (3, IC5

70 A series of 7-[4-(trifluoroacetyl)phenyl]-7-deazaadenine and -7-deazaguanine as well as 5-

71 ro-2H-purin-2,6-diamines 21-24 and 6-imino-1-phenyl-8,9-disubstituted-6,9-dihydro-1H-purin-2-(3H)-one

72 2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]- 9H-carbazole-1-carboxamide 6 (BMS-935177) was s

73 1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl ]acetamide, a helicase-primase inhibitor for the

74 edited synthesis of the trifluorinated alpha-phenyl acetic acid derivative required for the commercia

75 as been studied by subjecting rac-2-fluoro-2-phenyl acetic acid to the defluorination process.

76 y decarboxylation of oxo[4-(trimethylammonio)phenyl]acetic acid upon collision induced dissociation.

77 This new species reacts with ethylene and phenyl acetylene to give the [2+2] cycloaddition product

78 h a methoxycarbonyl group in position 2 with phenyl acetylene, styrene, and indene afforded polycycli

79 ffective synthetic pathway for derivation of phenyl alcohols.

80 ates, we found that the aromatic ring of the phenyl aliphatic amines may form cation-pi interaction w

81 to the discovery of the 3-Me,5-acrylonitrile-phenyl analogue RP-13s (IDX899) having an EC50 of 11 nM

82 properties, such as 3,5-bis(trifluoromethyl)phenyl and boronate ureas.

83 through Ge to Sn and from R = methyl through phenyl and p-styryl to 1-naphthyl provides a more compre

84 e highly disfavored when generating unstable phenyl and primary alkyl radicals.

85 l)pentiptycenes 2 (aryl = 4-(trifluoromethyl)phenyl) and 3 (aryl = mesityl) have been prepared and in

86 individual contribution of the hydrophobic (phenyl) and electrostatic (carboxyl) moieties using fluo

87 ion between aryl-BF3K salts (aryl = mesityl, phenyl) and lithiated bromonapthalene derivatives LiNaph

88 he same holds for N,N'-Dipp [2,6-di(2-propyl)phenyl] and N,N'-Mes [2,4,6-trimethylphenyl] substitutio

89 eaction of a C-based nucleophile, namely the phenyl anion, with the ferric heme nitrosyl [(OEP)Fe(NO)

90 d radiochemical yield from the corresponding phenyl(aspergillitine)iodonium salt.

91 type radical with an amide group replacing a phenyl at the C(3)-position.

92 ) and 2-methyl-4-[(2E)-1-methylbut-2-en-1-yl]phenyl azide (1b)) was studied in acetonitrile.

93 f polymerization conditions with thienyl- or phenyl-based substrates, whether they are electron-rich

94 ylthio)-1H-imidazol-5-y l)pyridin-2-yl)amino)phenyl)benzamide (7) inhibits the JNK3 in the subnanomol

95 )-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amin o)phenyl)benzamide dihydrochloride] and 2 [N-(3-chloro-4-(

96 el GDC-0449 analogs using N-[3-(2-pyridinyl) phenyl] benzamide scaffold.

97 chloro-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}benzamide (ChemBridge ID5217941)] sharing a N-phe

98 e C by 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide.

99 Our prior study identified phenyl benzenesulfonyl hydrazide 2 as a potent in vitro

100 onist [N2-2-2-oxoazepan-3-yl amino] carbonyl phenyl benzo (b)thiophene-2-carboxamide (ANA-12) into th

101 h-throughput screening, we have identified 2-phenyl benzo[d]isothiazol-3(2H)-ones as species-selectiv

102 2-Phenyl benzo[d]isothiazol-3(2H)-ones display nanomolar i

103 In this work, we demonstrate novel phenyl borate and carborane-based anions paired with a n

104 e of sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (NaTFPB), theoretical calculations, and si

105 Ar(F)4 (sodium tetrakis[(3,5-trifluoromethyl)phenyl]borate) was found to catalyze reactions of (Phebo

106 Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the

107 onsisting of a (porphinato)Zn donor (PZn), a phenyl bridge (Ph), and a naphthalene diimide acceptor (

108 Cu(2+), and Zn(2+) ions with 2-(3-hydroxy-1-phenyl-but-2-enylideneamino) pyridine-3-ol(HPEP) by orth

109 We discovered that chemical chaperone 4-phenyl butyric acid and antioxidant N-acetylcysteine, wh

110 t the nonclassical peroxisome proliferator 4-phenyl butyric acid is an efficient inducer of peroxisom

111 l lead, bioisosteres formed by replacing one phenyl by pyridine or pyrimidine showed improved solubil

112 is-PCBM) is purified from an as-produced bis-phenyl-C61 -butyric acid methyl ester (bis-[60]PCBM) iso

113 .9 % is achieved with devices based on [6,6]-phenyl-C61 -butyric acid methyl ester (PC61 BM).

114 rated for the poly(3-hexyl-thiophene) (P3HT)-phenyl-C61-butyric acid methyl ester (PCBM) mixture, and

115 phyrin is synthesized and blended with [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) to function

116 -yl)thieno[3,2-b]thiophene (PBTTT) and [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), to acquire

117 mo-tandem device with poly(3-hexylthiophene):phenyl-C61-butyric acid methyl ester as an active layer

118 EH-IDTBR or the fullerene derivative, [6,6]-phenyl C71 butyric acid methyl ester (PC71 BM) as electr

119 3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate (RL648_81), a new KCNQ2/3-specific acti

120 e analogue 16-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)hexadecanoic acid (13b) decreased

121 f the second carboxyl proton to the adjacent phenyl carbon and C-C cleavage in which the carboxyl pro

122 in six steps featuring a palladium-catalyzed phenyl carboxylation in the last step.

123 otocleavage of the Ar-Cl bond occurred and a phenyl cation chemistry resulted.

124 Over the past 80 years, phenyl cation intermediates have been implicated in a va

125 n and the role of the various intermediates (phenyl cations, diradicals, etc.) in the process was stu

126 important for inhibition, in particular the phenyl-chroman moiety.

127 olid-state structure of the mixed-valence mu-phenyl complex exhibits inequivalent copper centers, des

128 sonance spectroscopy of the mixed-valence mu-phenyl complex suggest that the degree of spin localizat

129 2-bis(2-formyl-4-((2E)-1-methylbut-2-en-1-yl)phenyl)diazene-1-oxide (13).

130 tor was 100-fold more potent than the parent phenyl-diketo acid with an IC50 value of 20 nm.

131 yraclostrobin, dibutyl phthalate, tert-butyl-phenyl diphenyl phosphate, and the isopropylated triaryl

132 role, results in the formation of 5-alkoxy-5-phenyl dipyrromethane derivatives, which function as rea

133 ,4'-diaminodiphenylmethane and 2-nitrophenyl phenyl ether 68% (w/w) as plasticizer casted on a conduc

134 t intramolecular rearrangement of cyclohexyl phenyl ether does not significantly contribute to alkyla

135 In this study, 5-substituted phenyl ether-linked aminoquinolines and derivatives were

136 romatic carboxyl groups, phenol, and methoxy phenyl ethers.

137 with auxin (IAA) and an auxin-inhibitor (a-(phenyl ethyl-2-one)-indole-3-acetic acid (PEO-IAA)), tog

138 s synthetic derivative, the N-(1-carbamoyl-2-phenyl-ethyl) butyramide, FBA, have been demonstrated to

139 uN2-specific antagonist, (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxa

140 ial cyclization cascade of 1,2-bis(2-ethynyl phenyl)ethyne on Ag(100).

141 n which the interplanar distance between two phenyl-extended viologen (ExV(2+)) chromophores is varie

142 esis of porphyrinoids carrying beta-to-ortho-phenyl fusions and expand on the scope and limits of the

143 g in the axial or equatorial location of the phenyl group and the angle of rotation about the Si-CPh

144 This effect may be profound: a 3,5-bis-CF3 phenyl group at C(5) in 1,3-dioxane displays a pronounce

145 Whereas one might expect an axial phenyl group at C(5) of 1,3-dioxane to adopt a conformat

146 wed to explain the axial predominance of the phenyl group by a larger polarization of the Si-Ph than

147 As follows from QTAIM analysis, the phenyl group is more stable when it is located in the ax

148 this study, analogues in which the terminal phenyl group of the dibemethin was replaced with a 2-pyr

149 metal catalyzed partial hydrogenation of the phenyl group to an enol ether.

150 tion of substituents around the NH group and phenyl group to improve the selectivity and potency of P

151 is linked to the para-position of one ZnTPP phenyl group to yield ZnTPP-PDI2.

152 group is cation-stabilizing relative to the phenyl group, albeit the 1,5 triazole is significantly d

153 Owing to the steric hindrance of the axle phenyl group, the threading of the guest was seen to occ

154 has a 3,5-dialkoxy substitution on the imide phenyl groups (CBI-35CH), leading to "molecular pockets"

155 oration of heterocycles at the C-5 position, phenyl groups at C-4, and a variety of differently subst

156 to the oxy group and sandwiched between two phenyl groups involving a unique ...c.g.phenyl interacti

157 ion-based kinetic resolutions and a role the phenyl groups play in that selectivity.

158 Analysis of the flipping modes of the mobile phenyl groups, their rotational rates, and transition te

159 to the ortho-positions of both adjacent meso-phenyl groups.

160 r rotors bearing three, five, six, and seven phenyl groups.

161 arboxy-8-hydroxy-9-methoxy-2-hydroxy-6-oxo-6-phenyl-hexa-2,4-dienoate.

162 via the palladium-catalyzed cyclization of O-phenyl hydroxamates onto a pendent alkene is reported.

163 Para-substituted phenyl-hydroxamic acids presented a more potent inhibiti

164 Os(eta(6) -p-cym)(5-R(1) -pyridylazo-4-R(2) -phenyl))I](+) (where p-cym=para-cymene) exhibit potent s

165 m the pi-conjugation extension by fusing two phenyls, IDTN shows stronger molecular aggregation, more

166 itors was designed based on our lead acyclic phenyl imidazole chemotype.

167 two phenyl groups involving a unique ...c.g.phenyl interaction [3.069(2), 3.146(3) A].

168 tert-butyl)phenyl)iodonium salts, as well as phenyl iodide, n-hexyl iodide, and n-dodecyl iodide, as

169 t-butylphenyldiazonium and bis(4-(tert-butyl)phenyl)iodonium salts, as well as phenyl iodide, n-hexyl

170 ntical withC bond and enhanced reactivity of phenyl isocyanide adsorbed at the Pd step edge compared

171 alyst at 3 nm resolution in real space using phenyl isocyanide as a probe molecule (Fig.

172 nthesized spiro-cyclopropyl pyrazolones with phenyl isothiocyanate and benzonitrile, respectively.

173 3,5-Bis-(trifluoromethyl)phenyl isothiocyanate, was used as a convenient reagent

174 s cage differs in that the central cavity is phenyl-linked rather than having the pyridyl core as in

175 erior affinity compared to a cyclohexane and phenyl linker.

176 inal observations on biphenyl synthesis from phenyl lithium and fluorobenzene in 1940.

177 WZB117 (2-fluoro-6-(m-hydroxybenzoyloxy) phenyl m-hydroxybenzoate) inhibits passive sugar transpo

178 -6-(2-pyridinyl)-4- pyrimidinyl]amino]methyl]phenyl]methanesulfonamide (GPR39-C3) at both canonical a

179 etamide), and NS6180 (4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one) inhibition

180 enes, selective aroylation took place in the phenyl moiety bearing the substituent.

181 nd the effect of methoxy substituents in the phenyl moiety have been studied.

182 exhibited regioselective aroylation of the 2-phenyl moiety irrespective of the absence or presence of

183 In addition, the presence of a 6-phenyl moiety is important and the best activity is reac

184 atives having an ortho- substituent in the N-phenyl moiety wherein the corresponding expected 3'-phen

185 bstituting group on the para position of the phenyl moiety, as supported by DFT calculations.

186 n withdrawing or electron donating) in the 3-phenyl moiety.

187 n of electron-donating methoxy groups in the phenyl moiety.

188 pectroscopic spin-trapping experiments using phenyl N-tert-butylnitrone (PBN) reveal the radical natu

189 ztrz)2(Pd(II)(CN)4)].n(guest) (bztrz = (E)-1-phenyl-N-(1,2,4-triazol-4-yl)methanimine, 1.n(guest)), h

190 We have recently disclosed 5-phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazol

191 (sp(3))-H bonds in the substrate [2-methyl-2-phenyl-N-(quinolin-8-yl)heptanamide], the energies for t

192 Two bifunctional alpha-phenyl-N-cyclohexyl nitrones were synthesized with the e

193 l group in comparison to the classical alpha-phenyl-N-tert-butylnitrone (PBN).

194 aled 2-chloro-N (1)-[4-chloro-3-(2-pyridinyl)phenyl]-N (4),N (4)-bis(2-pyridinylmethyl)-1,4-benzenedi

195 = Fe(eta(5)-C5H5)(eta(5)-C5H4); E = O; Ar = phenyl, naphthyls, (R)-BINOL, [3]ferrocenophanyl; E = N,

196 Nonsubstituted phenyl nitrenium ions (Ph-NH(+)) and phenyl oxenium ions

197 Only the 8-phenyl nucleoside shows strong fluorescence in polar apr

198 group of our typical hydrazone switch with a phenyl one leads to the long-lived negative photochromic

199 etermine how the structure of the substrate (phenyl or alkyl esters) is able to influence the guanidi

200 n-hexyl, n-decyl, n-tetradecyl, n-octadecyl, phenyl, or cyclohexyl).

201 tituted phenyl nitrenium ions (Ph-NH(+)) and phenyl oxenium ions (Ph-O(+)) have closed-shell singlet

202 isms for the BF3-promoted rearrangement of 2-phenyl oxiranyl MIDA boronate (1) and 1-phenyl oxiranyl

203 of 2-phenyl oxiranyl MIDA boronate (1) and 1-phenyl oxiranyl MIDA boronate (24) comprise two steps: r

204 is(pinacolato)diboron (B2Pin2) and N-cyano-N-phenyl-p-methylbenzenesulfonamide (NCTS) as reagents.

205 he electrophilic cyanating reagent N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) as the cyano source,

206 irected ortho C-H activation using N-cyano-N-phenyl-p-toluenesulfonamide as cyanating reagent in the

207 (isophthalate)3] window and three anthracene/phenyl panels.

208 ols, aromatics, sulfur-containing compounds, phenyls, phenols, and volatile fatty acids.

209 vary by about 7.5 kJ mol(-1) on going from a phenyl-phenyl to an anthracene-pyrene stack.

210 hate (24DIPPDPP), and bis(2-isopropylphenyl) phenyl phosphate (B2IPPPP) being the most prevalent ITP

211 titation to 1072 ng L(-1), with 2-ethylhexyl phenyl phosphate (EHPHP) and TCEP being the most abundan

212 , diphenyl phosphate (DPHP), isopropylphenyl phenyl phosphate (ip-PPP), tert-butylphenyl phenyl phosp

213 nal chromogenic ELISA test employing p-nitro-phenyl phosphate (pNPP).

214 phenyl phosphate (ip-PPP), tert-butylphenyl phenyl phosphate (tb-PPP), and bis(1-chloro-2-propyl) ph

215 series of biphenyl-N-[4-[4-(2,3-substituted-phenyl)piperazine-1-yl]alkyl]carbamates, a novel class o

216 e lead prodrug, isopropyl 6-diazo-5-oxo-2-(((phenyl(pivaloyloxy)methoxy)carbonyl)amino)hexanoate (13d

217 which are conjugatively linked through p-ter-phenyl (PPP), ter-thiophene (TTT) and alternating phenyl

218 s, and DFT calculations demonstrate that the phenyl prefers to lie over the dioxane ring in order to

219 eatment of the corresponding regioisomeric 1-phenyl-prop-2-en-1-yl acetates under the latter conditio

220 trimethoxyphenyl)-2-(3-methoxy-5-(prop-1-yl) phenyl)-propan-1-ol, (2) benzenemethanol; alpha-[1-[2,6-

221 ivity of the hydroarylation of 3-substituted phenyl propargyl ethers catalyzed by cationic Au(I) comp

222 the presence of europium triflate and (R,R)-phenyl-pybox.

223 ine in the fenestration region and for the 4-phenyl-pyran in the pore lumen, which could both be conf

224 conformation or interfere with gating, the 4-phenyl-pyran was found to be a classical pore blocker th

225 ihydropyridine nifedipine and an isosteric 4-phenyl-pyran.

226 trazol-1-yl)-1-(5-(4-(2,2,2-trifl uoroethoxy)phenyl)pyridin-2-yl)propan-2-ol).

227 exes LCuOH (L = N,N'-bis(2,6-diisopropyl-4-R-phenyl)pyridine-2,6-dicarboxamide, R = H or NO2, or N,N'

228 on of GM-CSF plus the MIF inhibitor 4-iodo-6-phenyl-pyrimidine achieved the best reprogramming respon

229 dopaminergic neurons potentiated 1-methyl-4-phenyl pyrinidium (MPP(+))-induced neuronal death.

230 ntify a probable route for the initiation of phenyl radical from iodobenzene.

231 ncomitantly, the nitrene PhNBN is formed via phenyl rearrangement.

232 featured by different substituents on the 2-phenyl ring (R) and at position 6 (R6), was synthesized

233 gs of neighboring ligand molecules [I2(II)...phenyl ring = 3.378(9) and 4.228(5) A].

234 ontal lineO oxygen and ortho-hydrogen of the phenyl ring and the OH...O hydrogen bond were determined

235 ctivity profile and that substituents on the phenyl ring are well accommodated by the GluK1 receptor.

236 p in a 1,8-relationship to a metal-complexed phenyl ring bearing various substituents have been synth

237 hydrophobic pocket to accommodate the alpha-phenyl ring in the ligand.

238 ta position of the symmetrically substituted phenyl ring is expected to form axially chiral hydroxyla

239 radical cyclization of an alkyl radical to a phenyl ring is faster than the respective 5-exo radical

240 of isomeric phenylphenalenones in which the phenyl ring is located at all possible peripheral positi

241 2) inhibitor series comprising a substituted phenyl ring joined to a dimethylpyridone moiety via an a

242 f ciprofloxacin, a perfluoroaryl ring, and a phenyl ring linked by an amidine bond, were efficiently

243 Direct ortho amidation at the phenyl ring of 2-phenylimidazo heterocycles with aryl is

244 Selective deprotonation of the pro-S P-phenyl ring of 5 was ascertained through NOE measurement

245 states, more effective C-H...pi (between the phenyl ring of the EPK and the catalyst) and C-H...O int

246 , or S) linking the pyrrolidine ring and the phenyl ring plays a key role in the receptor selectivity

247 borate anions bound on the outside, with one phenyl ring pointing into the cavity.

248 e of the substituent and its position on the phenyl ring significantly impact the magnitude of the el

249 of the sulfur-centered radical cation and a phenyl ring stabilized by the fibril framework.

250 idth and splitting of the C horizontal lineC phenyl ring stretches.

251 Introduction of two fluorine atoms on the phenyl ring yielded analogue 4y that displayed an IC50 o

252 access to differently substituted (mainly on phenyl ring) indoles and 1-benzothiophenes from the reac

253 The through-space shielding effects of the phenyl ring, as a function of substituent and complexing

254 ng groups (EWGs) like nitro and cyano at the phenyl ring, leading to absorption in the green to red r

255 pimer, when large groups are attached to the phenyl ring.

256 photoluminescence properties of a series of phenyl-ring molecular rotors bearing three, five, six, a

257 azine), biaryl extension, and replacement of phenyl rings by pyridine.

258 2 nanosheets are functionalized with organic phenyl rings containing electron donating or withdrawing

259 cation of the loop, since the removal of the phenyl rings from the rigid loop restores drug transport

260 rphyrin bearing six pendant OH groups on the phenyl rings in all ortho and ortho' positions was immob

261 I2(II) is located interstitially between two phenyl rings of neighboring ligand molecules [I2(II)...p

262 rformed via alteration of the characteristic phenyl rings to alternative aromatic systems.

263 Small, apolar aromatic groups, such as phenyl rings, are commonly included in the structures of

264 fused aromatic structure with two additional phenyl rings, further rigidifying the polymer backbone.

265 xcept when the host and guest differ by four phenyl rings, when the inclination angle becomes >40 deg

266 .4 and 13.3 kcal/mol for the pro-R and pro-S phenyl rings.

267 best when the host and guest differ by five phenyl rings.

268 occurs when the CPP nanohoops differ by five phenyl rings.

269 occur when the host and guest differ by five phenyl rings.

270 A mild, practical, and simple procedure for phenyl selenoesters synthesis from several anhydrides an

271 The postulated 1,2-phenyl shift as origin for the side reaction could be pr

272 udy of its reactivity showed that isopropoxy(phenyl)silane is an exceptionally efficient stoichiometr

273 symmetric ligand motif with meta-substituted phenyl spacers, which enables the host to initially self

274 fabricated using the photoactivatable dye N-phenyl spirolactam rhodamine B, a commercial picoproject

275 an electron-deficient p-cyano group on the B-phenyl substituent creates a twisted intramolecular char

276 This enabled the effect of the phenyl substituent to be evaluated and compared to other

277 nyl substituents on phosphorus and benzyl or phenyl substituents on nitrogen were employed, and the c

278 erent P(R)2N(R')2 ligands with cyclohexyl or phenyl substituents on phosphorus and benzyl or phenyl s

279 c)(eta(2)-C2H4)2]2 catalyzes production of 1-phenyl substituted alkene products via oxidative arene v

280 We find that the 'C-DIM' NR4A ligands, para-phenyl substituted di-indolylmethane compounds, enhance

281 logues of privileged bis(3,5-trifluoromethyl)phenyl substituted thioureas, and are found to be much m

282 orward protocol for the synthesis of certain phenyl-substituted carboxylic acids from 2-phenylcycloal

283 at, upon an increase in the concentration of phenyl-substituted dihomooxacalix[4]arene bidentate urea

284 New Si-phenyl-substituted silacyclohexanes and 3-silatetrahydro

285 showed competitive C-S bond cleavage giving phenyl sulfinic acid and ionization to diphenyl sulfide

286 o acid enolates with beta,beta-difluorovinyl phenyl sulfone, a new (1'-fluoro)vinyl cation equivalent

287 via formation of a higher-energy protonated phenyl tautomer (2H(+)) prior to C-C bond breaking would

288 though the nature of the substituents on the phenyl tethering ring did not alter the stereochemical o

289 Phenyl(thioxo)phosphine oxide formed in the thionation r

290 stituted at positions 5 and 5' with thienyl, phenyl, TMS-ethynyl, and vinyl groups is reported herein

291 The ester 4-((tosyl-l-alanyl)oxy)phenyl tosyl-l-alaninate (TAPTA) was synthesized and tes

292 tion between 1-phenylpyrrolidine (PhPyr) and phenyl trans-styryl sulfone by visible-light-absorbing c

293 whereby the selected ethylene-bridged hybrid phenyl ultra-high-performance liquid chromatography stat

294 lity to efficiently delocalize the spin on a phenyl unit, starkly contrary to general chemistry knowl

295 grees ) in TTT-NN and TPT-NN than for NN and phenyl units ( approximately 29 degrees ) in PPP-NN were

296 henyl)-3-(3-(6-(pyrrolidin-1-yl)pyridin-2-yl)phenyl)urea (PSNCBAM-1, 2) bound the cannabinoid recepto

297 ctivity and selectivity, proving superior to phenyl vinyl sulfone 1 and with clear advantages over bi

298 r*SnH3 (Ar*=2,6-(2',4',6'-triisopropylphenyl)phenyl) was treated with the well-known frustrated Lewis

299 u-NTer)]2 (Ter=2,6-bis(2,4,6-trimethylphenyl)phenyl) was utilized in the activation of stable small m

300 bis(diisopropylphenyl-benzimidazol-2-ylidene)phenyl); X = Cl or Br) with halogen and halogen surrogat