ライフサイエンスコーパス: phenylthio

1 xyandro-stenedione (4-OHA), 7alpha-(4'-amino)phenylthio-1, 4-androstandiene-3,17-dione (7alpha-APTADD

2 oxyandrostenedione (4-OHA), 7alpha-(4'-amino)phenylthio-1,4-androstandiene-3,17-dione (7alpha-APTADD)

3 [4-hydroxyandrostenedione, 7alpha-(4'-amino)phenylthio-1,4-androstandiene-3,17-dione, and bridge (2,

4 hat the selective Epac activator 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3', 5-cyclic monophosph

5 cific cAMP analog 8CPT-2Me-cAMP (8-(4-chloro-phenylthio)-2'-O-methyladenosine-3',5'-cAMP) activates R

6 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosph

7 8-(4-Chloro-phenylthio)-2-O-methyladenosine-3'-5'-cyclic monophospha

8 , N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-bromobenzylamine (36), and N, N-dimethyl-2

9 : N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-fluorobenzylamine (35), N, N-dimethyl-2-(2

10 d N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-iodobenzylamine (37).

11 Under these conditions, 6-phenylthio-5,6,7,8-tetrahydronaphthalenes are formed dia

12 sis of all four stereoisomers of 5-hydroxy-6-phenylthio-5,6-dihydrothymidine (T*), which, upon 254 nm

13 esis of 2,4,6-trisubstituted pyridines from (phenylthio)acetic acid and a range of alpha,beta-unsatur

14 reactions of imines and enamines with alpha-phenylthio, alpha-phenylsulfonyl, and alpha-diethylphosp

15 N-amidinyliminium ion generated from alpha-(phenylthio)amidine precursor 16 by reaction with Cu(OTf)

16 (2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzenamine (4'-2-fluoroethoxy derivatives 28

17 Tris(phenylthio)benzene molecules have been synthesized in or

18 th (11)C-3-amino-4-(2-[(dimethylamino)methyl]phenylthio)benzonitrile ((11)C-DASB).

19 thly with the crypt[2.1.1] complex of alpha-(phenylthio)benzyllithium as the initiator and enolate as

20 126 (1,4-diamino-2,3-dicyano-1,4-bis[2-amino-phenylthio]butadiene) blocked ERK phosphorylation, and a

21 126 (1,4-diamino-2,3-dicyano-1,4-bis[2-amino-phenylthio]butadiene), demonstrating that signaling path

22 the histone deacetylase inhibitor methyl-4-(phenylthio)butanoate, which we subsequently administered

23 Here, we found that 4-(phenylthio)butanoic acid (PTBA) expanded the expression

24 The most powerful inhibitor was 5'-p-Cl-phenylthio-DADMe-Immucillin-A (pClPhT-DADMe-ImmA) with a

25 p-Cl-phenylthio-DADMe-immucillin-A binds with a dissociation

26 he 5'-position at the catalytic site with 5'-phenylthio-DADMe-immucillin-A gave a dissociation consta

27 ser-flash photolysis of the corresponding N-(phenylthio) derivatives, and the rate constants for the

28 The ring contraction reaction of methoxy- or phenylthio-diazepinones under acidic conditions resulted

29 gioselective synthesis of phenoxy esters and phenylthio esters is reported.

30 l]-1H-imidazole and 4-[2-(3-(trifluoromethyl)phenylthio)ethyl]-1H-imidazole are shown to be partial a

31 titution of the methylthio group with a p-Cl-phenylthio group gives a more powerful inhibitor with a

32 itution of the 5'-methylthio group with a 5'-phenylthio group gives an equilibrium binding constant o

33 y chiral selenophosphoramides afforded alpha-phenylthio ketones in generally high yield and with good

34 The substituted (phenylthio)methane boronate was converted to the corresp

35 lowed to react with the stabilized anion of (phenylthio)methane boronate, PhSCH(2)BO(2)C(6)H(12), to

36 (10), and four nonclassical 2,4-diamino-5-((phenylthio)methyl)pyrrolo[2,3-d]pyrimidines with 3',4'-d

37 tion-conjugate addition reaction to form 1-[(phenylthio)methyl]-5-[(ethoxycarbonyl)methyl]-6-acetamid

38 In contrast, the synthesis of 3-[(phenylthio)methyl]cyclohex-2-en-1-one (6) and 3-(1,3-dit

39 Although 4-(phenylthio)-N-(4-phenyl-2-oxobutyl)azetidin-2-one, SB-21

40 is the S homologue 4-[3-(3-(trifluoromethyl)phenylthio)propyl]-1H-imidazole and its CH(2) isostere 4

41 These 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides take advantage of an a

42 ,5'-cyclic monophosphorothioate, 8-(4-chloro-phenylthio) (R(p)-8-pCPT-cGMPs), or DT-2 blocked the ant

43 ese donors showed higher reactivity than the phenylthio sialosides and could be activated by NIS/TfOH

44 es of 2-(phenylamino), 2-(phenyloxy), and 2-(phenylthio) substitutions, the order of affinity at the