ライフサイエンスコーパス: pheromone receptor

1 2 gene, which encodes the yeast alpha-mating pheromone receptor.

2 oskeleton toward a landmark generated by the pheromone receptor.

3 ncodes a putative seven-transmembrane domain pheromone receptor.

4 osporin A inhibits activation of the peptide pheromone receptor.

5 y deficit support a role of V1r receptors as pheromone receptors.

6 eceptor (Vr) genes are regarded as candidate pheromone receptors.

7 pear to represent a second family of odorant/pheromone receptors.

8 nasal cavity by sensory neurons that express pheromone receptors.

9 (v) taste papilla receptors and (vi) fungal pheromone receptors.

10 tors distantly related to putative mammalian pheromone receptors.

11 ric G proteins associated with transmembrane pheromone receptors.

12 a-aminobutyric acidB receptors, and putative pheromone receptors.

13 an sensory neurons require the expression of pheromone receptors.

14 c glutamate, gamma-aminoisobutyric acid, and pheromone receptors.

15 predicted to encode multiple pheromones and pheromone receptors.

16 genes are likely to encode a novel family of pheromone receptors.

17 ) and to positive regulation by cell-surface pheromone receptors.

18 ent of the role of several mammalian V1Rs as pheromone receptors.

19 gene families are likely to encode mammalian pheromone receptors.

20 lement the 7-transmembrane family of odorant/pheromone receptors.

21 hylamine, rivaling those seen with mammalian pheromone receptors.

22 fic genes, in addition to the pheromones and pheromone receptors.

23 heromones sensed through seven-transmembrane pheromone receptors.

24 ein coupled receptors thought to function as pheromone receptors.

25 courtship and are thus candidate Drosophila pheromone receptors.

26 erleukins, natural killer-cell receptors and pheromone receptors.

27 receptor with sequence similarity to fungal pheromone receptors.

28 -coupled receptors (GPCRs) similar to fungal pheromone receptors.

29 g by either of its cognate G protein-coupled pheromone receptors.

30 y at the cell surface, constitutively active pheromone receptors accumulate in post-endoplasmic retic

31 Mating pheromone receptors activate a G protein signal pathway

32 The alpha-factor pheromone receptor activates a G protein signaling casca

33 The alpha-factor pheromone receptor activates a G protein signaling pathw

34 The pheromone receptor alleles from Microbotryum appeared as

35 o large families of biosynthetic enzymes and pheromone receptors, although the factors controlling th

36 White cells, like opaque cells, possess pheromone receptors, although their distribution and red

37 d a large cluster of genes encoding a single pheromone receptor and eight different pheromones.

38 racterize the relationship between the PRE-2 pheromone receptor and its ligand, CCG-4, and the genera

39 clear which Galpha subunit is coupled to the pheromone receptor and response pathway.

40 large multi-molecular complexes that include pheromone receptors and beta2-microglobulin (beta2m).

41 mating-type genes, which encode pheromones, pheromone receptors and homeodomain transcription factor

42 ss insect orders, dimerizes with odorant and pheromone receptors and is required for efficient locali

43 aviors have entered a new area, as candidate pheromone receptors and signaling molecules have been id

44 ivated signalling cascade as the Ste3a/alpha pheromone receptors, and thereby competes for pathway ac

45 VNO pheromone receptors are encoded by the V1r and V2r gene

46 Candidate pheromone receptors are encoded by two distinct and comp

47 gamma-aminobutyric acid type B receptor, and pheromone receptors are enlisted in a distinct family wi

48 lines of evidence strongly suggest that the pheromone receptors are two allelic sequences acting to

49 discovered, whether it represents an odorant/pheromone receptor as has been suggested for the large f

50 oughs in the deorphanization of codling moth pheromone receptors, as well as more broadly into insect

51 Tpn also bound to M10.5, a pheromone receptor-associated MHC molecule that has an o

52 A sex pheromone receptor BmOR1 is specifically tuned to bombyk

53 We propose that actin-mediated pheromone receptor clustering might consolidate signalli

54 We propose that PRE-1 is a pheromone receptor coupled to GNA-1 that is essential fo

55 The G beta gamma complex of the pheromone receptor-coupled G protein activates the signa

56 A1, which encodes the G alpha subunit of the pheromone receptor-coupled G protein.

57 andida species and indicates that functional pheromone-receptor couples exist in fungal species that

58 Unlike the other reported fungal pheromone receptors, CPRa shows functional diversity.

59 gene, a MATalpha-specific myosin gene, and a pheromone receptor (CPRalpha) were identified within the

60 It is not surprising that pheromone receptor differences could control H. subflexa

61 The alpha-mating pheromone receptor encoded by the yeast STE2 gene is a G

62 Pheromone receptors encoded by the mating-type locus (MA

63 The alpha-factor mating pheromone receptor (encoded by STE2) activates a G prote

64 en the C5a receptor and a co-expressed yeast pheromone receptor (encoded by STE2), indicating that C5

65 In vivo Prk1p inhibition blocked pheromone receptor endocytosis, and caused cortical acti

66 itro, ECB(Z) odorant receptor 3 (OR3), a sex pheromone receptor expressed in male antennae, responds

67 in subunit expressed, the family of putative pheromone receptor expressed, and termination site of th

68 amily comprises one of two types of putative pheromone receptors expressed in the mammalian vomeronas

69 ons are distinct from neurons expressing the pheromone receptor families V1R and V2R.

70 rst direct evidence that a member of the sex pheromone receptor family in moth species mediates consp

71 emales, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone.

72 urons expressing Gr68a, a putative gustatory pheromone receptor for female cuticular hydrocarbons tha

73 amily (GFB) consists of homologs of putative pheromone receptors found in the vomeronasal organ (VNO)

74 A phylogenetic tree built using other known pheromone receptors from basidiomycetes showed that tran

75 The mouse V1R putative pheromone receptor gene family consists of at least 137

76 ng types of U. hordei, respectively, and the pheromone receptor gene Uhpra2 from MAT-2 cells.

77 fied initially as an insertion in the Bbeta2 pheromone receptor gene, bbr2, leading to a partial defe

78 hnology to introduce mutations in a putative pheromone receptor gene, VR2, in the germline of mice.

79 tains at least three pheromone genes and one pheromone receptor gene, which function similarly to the

80 contributions of V1Rs versus other candidate pheromone receptor genes in the establishment of complex

81 ars ago, and that the random inactivation of pheromone receptor genes is an ongoing process even in p

82 at vomeronasal organ of a family of putative pheromone receptor genes that bear no sequence similarit

83 ies such as the major histocompatibility and pheromone receptor genes, but there are also many single

84 ation of these genes, which include putative pheromone receptor genes, has offered a new opportunity

85 s, occurs by reproducible genetic changes to pheromone receptor genes.

86 may express the same or functionally related pheromone receptor genes.

87 we report the identification of the putative pheromone receptor GR68a, which is expressed in chemosen

88 east pheromone pathway in the absence of the pheromone receptor, has a domain with four such repeats.

89 More than 250 putative pheromone receptors have been identified in the mouse VN

90 Gpa2 interacted with the pheromone receptor homolog Ste3alpha, Gbeta subunit Gpb1

91 also required for the activation of the moth pheromone receptor HR13 by its lipid-derived pheromone l

92 signal transducer for the G protein-coupled pheromone receptor in Saccharomyces cerevisiae, we postu

93 lated classes of fungi than to the alternate pheromone receptor in the Microbotryum species.

94 re likely to represent a new large family of pheromone receptors in mammals.

95 eronasal sensory neurons, are believed to be pheromone receptors in rodents.

96 expand the repertoire of candidate taste and pheromone receptors in the fly.

97 Pheromone receptors in the mammalian VNO are encoded by

98 Here, we analyzed sequences of two pheromone receptors in the Microbotryum fungal species c

99 Phylogenetic trees of pheromone receptors in the Microbotryum species complex

100 The a-factor receptor (Ste3p) is one of two pheromone receptors in the yeast Saccharomyces cerevisia

101 omone substances have been identified as sex pheromone receptors in various moth species.

102 esidues of the yeast Ste2p G protein-coupled pheromone receptor, including the negatively charged N-t

103 Overexpression of the pheromone receptors increased the mating of some of the

104 sicochemical and functional diversity within pheromone-receptor interaction sites.

105 ul system for exploring molecular aspects of pheromone-receptor interactions for a class of seven-tra

106 To also address pheromone-receptor interactions in related species, incl

107 A complex set of pheromone-receptor interactions maximizes the likelihood

108 y, we have demonstrated that this C.cinereus pheromone receptor is a G-protein-coupled receptor and t

109 The yeast alpha-factor pheromone receptor is a member of the G-protein-coupled

110 The yeast pheromone receptor is also uniformly distributed on the

111 signaling receptors, the yeast alpha-factor pheromone receptor is downregulated by hyperphosphorylat

112 mammalian V1Rs, and its putative function as pheromone receptor is reminiscent of the role of several

113 A pheromone receptor-like gene, CPR2, was discovered that

114 ce in and around the mating-type determining pheromone receptor locus in the SR, suggesting a recent

115 one-independent variant of the extracellular pheromone receptor, LUSH.

116 Engagement of pheromone receptors Map3 and Mam2 [3, 4] with their cogn

117 sequenced both the transcription factor and pheromone receptor mating-type gene homologs from C. dis

118 HD1 and HD2) and B (pheromone precursors and pheromone receptors) mating genes in M. roreri.

119 e specificity of more broadly responsive sex pheromone receptors may provide a mechanism that contrib

120 eromones, but none of these compounds or the pheromone-receptor neurons that sense them have been ide

121 asma membrane-tethered Gbetagamma freed upon pheromone receptor occupancy, thereby initiating downstr

122 Our results suggest that the MATa pheromone receptor of C. neoformans is not only required

123 ven mating type were all more similar to the pheromone receptors of distantly related classes of fung

124 e olfactory and visual systems: the putative pheromone receptors of the VNO are evolutionarily indepe

125 uition suggests that uniform distribution of pheromone receptors over the cell surface would yield op

126 The specificity of interaction among pheromone-receptor pairs in Schizophyllum was reproduced

127 Thus, Npn-2 and candidate pheromone receptors play distinct and complementary role

128 1, CpomOR3 and CpomOR6a, which belong to the pheromone receptor (PR) lineage, and the co-receptor (Cp

129 pCF10 is regulated by the interaction of the pheromone receptor protein PrgX with two DNA binding ope

130 We present the crystal structure of the pheromone receptor protein PrgZ from Enterococcus faecal

131 is the mating pathway triggered by pheromone/pheromone receptor recognition.

132 Species-specific pheromone receptor repertoires may partly explain specie

133 from the target promoter is controlled by a pheromone receptor/repressor protein whose activity is d

134 ain transcription factors and pheromones and pheromone receptors, respectively.

135 These proteins are cytoplasmic pheromone receptors sharing a structurally similar phero

136 f Afr1p, a protein that negatively regulates pheromone receptor signaling and is required for normal

137 f Afr1p, a protein that negatively regulates pheromone receptor signaling and is required to form poi

138 t2, a GTPase-activating protein that dampens pheromone receptor signaling.

139 dy, we first define the domains of the alpha-pheromone receptor Ste2 that are necessary for signaling

140 pigment rhodopsin and the yeast alpha-factor pheromone receptor Ste2, respectively.

141 calis biofilm formation was dependent on the pheromone receptors Ste2 and Ste3, confirming the role o

142 The alpha-factor pheromone receptor (STE2) activates a G protein signal p

143 The yeast alpha-factor pheromone receptor (Ste2) belongs to the large superfami

144 sitive mutant form of the yeast alpha-factor pheromone receptor (ste2-3) was found to provide a model

145 e the active state of the yeast alpha-mating pheromone receptor Ste2p, a member of the superfamily of

146 first intracellular loop, IC1, of the alpha-pheromone receptor Ste2p, is required for the alpha-pher

147 to direct uptake of a truncated form of the pheromone receptor Ste2p.

148 The alpha-factor pheromone receptor (Ste2p) of Saccharomyces cerevisiae i

149 The alpha-factor pheromone receptor (Ste2p) of the yeast Saccharomyces ce

150 yeast Saccharomyces cerevisiae alpha-factor pheromone receptor (Ste2p) was used as a model G protein

151 s) by analyzing constitutively active mating pheromone receptors (Ste2p and Ste3p) of the yeast Sacch

152 The Saccharomyces cerevisiae alpha-factor pheromone receptor, Ste2p, has been studied as a model f

153 The inappropriate expression of the a-factor pheromone receptor (Ste3p) in the MATa cell leads to a s

154 The alpha-factor pheromone receptor stimulates MATa yeast cells to underg

155 al for pheromone response because it couples pheromone receptor stimulation to activation of the appr

156 The two yeast pheromone receptors, the a and alpha-factor receptors, s

157 compartments expressing distinct families of pheromone receptors, the V1Rs and the V2Rs.

158 the gpa1Val50 mutant was independent of the pheromone receptor; therefore, it results from intracell

159 cascade that transduces the signal from the pheromone receptor to a transcriptional response in the

160 d sequence of 73 V1R genes encoding putative pheromone receptors to identify regulatory features and

161 ch G proteins transmit a signal from peptide pheromone receptors to the mating response in yeast and

162 genes encoding the TRP2 ion channel and V1R pheromone receptors, two components of the vomeronasal p

163 factors known as "Rgg proteins" are peptide pheromone receptors ubiquitous in Firmicutes.

164 ecies is possible, we experimentally evolved pheromone receptors under conditions that imposed high f

165 ve no significant homology to other putative pheromone receptors (V1Rs) or to olfactory receptors but

166 and mouse odorant receptors (ORs) and type 1 pheromone receptors (V1Rs) using the mm5 (mouse) and rn3

167 and appear distantly related to the putative pheromone receptors, V1Rs, and the taste receptors, T2Rs

168 unit (also known as Gnao) and Vmn2r putative pheromone receptors (V2Rs).

169 that codes for a diverse array of candidate pheromone receptors (VRs) expressed by the G alpha(o)+ s

170 The ortholog of Ste3, an a-factor pheromone receptor, was cloned and genes surrounding the

171 Identification of dauer pheromone receptors will allow a better understanding of

172 to encode three lipopeptide pheromones and a pheromone receptor with a seven-transmembrane domain.