ライフサイエンスコーパス: phi

1 ence and settles proportionally to exp(-mu/D Phi).

2 H in the intracellular side of the membrane (pHI).

3 rter NBCn1 which regulates intracellular pH (pHi).

4 h stages on the Pre-harvest Interval Period (PHI).

5 ohistidine (1-pHis) or 3-phosphohistidine (3-pHis).

6 in the Pediatric Health Information System (PHIS).

7 are jointly considered with respect to d and phi.

8 strongly regulated by Ca(2+) and less so by pHi.

9 ed randomised population of individuals with PHI.

10 hen performing dissipation studies to define PHI.

11 eleases two virus-encoded peptides, mu1N and Phi.

12 peptides, myristoylated mu1N (myr-mu1N) and Phi.

13 emissive than cytidine (lambdaem 398-420 nm, Phi 0.009-0.687), and excellent correlation was found be

14 riodic oscillations, anti-correlated between Phi = 0 and Phi0/2.

15 = pi) to that of a perfect magnetic mirror (phi = 0).

16 The sole isolated interlocked photoproduct (Phi = 0.06) is a [2]rotaxane, with the dimerized anthrac

17 ity and adaptive functioning groups was low (phi = 0.13, P < .05).

18 in with visual sensations (chi-square, 3.91; Phi = 0.15; df, 1; P < 0.05) and seeing with visual sens

19 eing were intercorrelated (chi-square, 5.47; Phi = 0.18; df, 1; P < 0.05), pain with visual sensation

20 g with visual sensations (chi-square, 34.22; Phi = 0.45; df, 1; P < 0.001).

21 nol, which is slightly lower than that of 1, Phi = 0.88(2), in the same solvent (lambdairr = 460 nm).

22 Phi(0), is given by (chi1((3))-ichi2((3))) x Phi(0), and that the interference between this product a

23 ty and the interfacial potential, chi((3)) x Phi(0), is given by (chi1((3))-ichi2((3))) x Phi(0), and

24 that this newly identified term, ichi((3)) x Phi(0), which is out of phase from the surface terms, is

25 2730 m(2) einstein(-1)), and quantum yields (Phi) (0.03-0.95 mol einstein(-1)).

26 e sintered into porous, bulk nanocomposites (phi 10 mmxh 10 mm) with low kappa (0.48 W m(-1) K(-1) )

27 jects enrolled during primary HIV infection (PHI), 10 chronically infected subjects (chronic), and 7

28 80% of PHI enrollment samples and in 100% of PHI 12-month, chronic, and EC samples; it peaked after a

29 t spherical carbonate concretions (diameters phi : 14 ~ 37 mm) around tusk-shells (Fissidentalium spp

30 The Phi(2)GFP10 reporter phage showed high sensitivity for d

31 developed a more powerful mycobacteriophage (Phi(2)GFP10) with a fluorescent reporter.

32 Sputum was incubated with Phi(2)GFP10, in the presence and absence of RIF, and bac

33 The model we used is a square lattice with a phi(4) potential between next-nearest-neighbour sites, w

34 errupt open bursts, was greatly increased at pHi 5.8 and 6.3.

35 D all abolished the prolongation of taucf at pHi 6.3.

36 When compared with the control (pHi 7.3), acidifying pHi to 6.3 or alkalinizing pHi to 8

37 een pCO2 (a function of tumor perfusion) and pHi (a potent modulator of cancer cell physiology).

38 onstrated clinically relevant utility of the PHI across threshold probabilities of 5-30%.

39 : 1) complex 2, originating from the initial PhI activation with 3, is roughly as reactive toward PhI

40 In summary, the PHI adds predictive performance to image-guided detectio

41 ast to the trends in the metal work function Phi(Ag)<Phi(Au).

42 In mpMRI negative men, the PHI again improved prediction of significant cancers; AU

43 Increased pHi also occurs with mESC differentiation and, when prev

44 Phi and %p2PSA have a high diagnostic accuracy rates and

45 Phi and %p2PSA may be useful as tumor markers in predica

46 ative energy differences between the 5fdelta/phi and 5fpi*/5fsigma* orbitals as a qualitative measure

47 l to simultaneously determine the changes of pHi and [Cl(-)]i in response to hypercapnia and seizure

48 nction as reflected in elevated steady-state pHi and accelerated recovery from intracellular acidosis

49 a relationship between the HOMO-LUMO gap and Phi and explained the loss of fluorescence in the nitro

50 ied by the MCT1 inhibitor decreasing further pHi and glycolysis.

51 IKSper in human sperm is activated weakly by pHi and more strongly by Ca(2+).

52 four deep learning architectures to predict phi and psi angles of protein backbone.

53 The mean absolute error (MAE) of phi and psi angles predicted by DRNN, DReRBM, DRBM and D

54 lomycin had only a small effect upon resting pHi and recovery following an acid load.

55 ptation duration was short (188 ms), reverse-phi and regular motion led to similar adaptation effects

56 on duration was increased to 752 ms, reverse-phi and regular motion showed distinct adaptation effect

57 reservoir in patients initiating cART during PHI and to assess the impact of the timing of cART initi

58 ccurred in a large fraction of patients with PHI and were associated with substantial morbidity.

59 31-45 to 15-23 events; a shorter duration of PHI and/or a lower testing frequency reduces the number

60 s to screen, select, and characterize anti-1-pHis and anti-3-pHis mAbs.

61 is a powerful regulator of intracellular pH (pHi) and extracellular pH (pHo), and contributes to solu

62 ll-interfering RNA lowered intracellular pH (pHi) and induced apoptosis.

63 n one season by individuals of the same age (phi) and lifetime variance in reproductive success of in

64 at three constant pH levels: the initial pH (pHi) and pH 6.5 and 5.5.

65 during (acute/early) primary HIV infection (PHI) and up to one year post-infection (p.i).

66 he lipid-facing interface (DeltaDeltaG(0)w,i(phi)) and the protein-facing interface (DeltaDeltaG(0)w,

67 largely due to an enhanced dynamic response (PHId), and a more than twofold improvement in glucose to

68 The MAE of phi angle is comparable to the existing methods, but the

69 und in conformations that require a positive phi angle such as helical C-capping motifs or type I' an

70 structure (estimated space-filling fraction phi approximately 0.59) which has not been anticipated b

71 Intracellular chloride ([Cl(-)]i) and pH (pHi) are fundamental regulators of neuronal excitability

72 vation with 3, is roughly as reactive toward PhI as 3 itself; and 2) the Ph-I bond cleavage with the

73 rotocol based on selection medium containing Phi, as the sole source of phosphorus (P), can serve as

74 Parallel measurements of [Cl(-)]i and pHi at the single-cell level in the mouse cortex showed

75 he trends in the metal work function Phi(Ag)<Phi(Au).

76 toxin C5a as a master switch of the delicate pHi balance in neutrophils resulting in profound inflamm

77 Additional data types included into PHI-base 4 are the direct targets of pathogen effector p

78 (PHI-base) is available at www.phi-base.org PHI-base contains expertly curated molecular and biologi

79 Genes with associated PHI-base data can be easily identified across all plant

80 o associated with pathogenicity based on the PHI-base database.

81 Future plans for PHI-base include development of tools facilitating commu

82 PHI-base phenotypes were mapped via their associated gen

83 encountered and the future directions of the PHI-base project are briefly discussed.

84 Here we describe a revised PHI-base Version 4 data platform with improved search, f

85 The new release of PHI-base Version 4.2 (October 2016) has an increased dat

86 The Pathogen-Host Interactions database (PHI-base) catalogues experimentally verified pathogenici

87 The pathogen-host interactions database (PHI-base) is available at www.phi-base.org PHI-base cont

88 at integrates phenotypic data for genes from PHI-base, an expertly curated catalog of genes with expe

89 irectly curate their own published data into PHI-base.

90 ions database (PHI-base) is available at www.phi-base.org PHI-base contains expertly curated molecula

91 The contents of short B-chains of the phi, beta-LDs of amylopectins from the outer pericarp we

92 e higher (by approximately 3%) than those of phi, beta-LDs of the core amylopectins.

93 r unit chains of both amylopectins and their phi, beta-limit dextrins (LDs) than those of the outer p

94 PHIS billing data had higher sensitivity (> 50% for nine

95 view of Pediatric Health Information System (PHIS) billing and microbiology data were compared with c

96 al role of Slc26a6 in regulation of not only pHi, but also cardiac excitability.

97 combined two-photon imaging of [Cl(-)]i and pHi, but this has never been performed at the cellular l

98 n neutrophils to C5a significantly increased pHi by selective activation of the sodium/hydrogen excha

99 ST search function is provided and a link to PHI-Canto, a tool for authors to directly curate their o

100 otassium thioacetate (KSAc) and iodobenzene (PhI) catalyzed by CuI associated with 1,10-phenanthrolin

101 the two-electrode voltage-clamp technique or pHi changes using Vm/pH-sensitive microelectrodes.

102 ffect on tauo , taucf and their responses to pHi changes.

103 sults, researchers have proposed that a phi (Phi)-clamp composed of phenylalanine (Phe)427 residues o

104 ture reveals the long-sought-after catalytic Phi-clamp and the membrane-spanning translocation channe

105 s propargylic or homopropargylic, react with PhI(+)CN(-)OTf (Stang's reagent) or 3,5-(CF3)2C6H3I(+)CN

106 iability was moderate (G-coefficient = 0.67, Phi-coefficient = 0.52).

107 ar HCO3(-) concentrations and elevated brain pHi compared to control fish, providing evidence of CO2

108 with DeltaG() approximately 24 kcal/mol for PhI (computed DeltaG() = 21.9 kcal/mol).

109 ns LC-MS/MS spectra for potential matches to pHis-containing peptides based on their neutral loss pat

110 orkflow for the identification of endogenous pHis-containing proteins in cellular lysates.

111 ation, leading to putative identification of pHis-containing proteins.

112 ivation reactions involve PPh3 dissociation, PhI coordination to Ru through I, rearrangement to a eta

113 PHI could change according to the application time, beca

114 activated by Ca(2+) rather than by alkaline pHi; current-voltage relations of human Slo3 and human I

115 rs per 1000 patient-days), while the EMR and PHIS data endorsed a decrease of $12785 and $21380 per 1

116 With 3 years of PHIS data on 48887 children, an asthma template was cons

117 mpared with EMR and PHIS data, while EMR and PHIS data were comparable in magnitude of savings.

118 estimated cost savings compared with EMR and PHIS data, while EMR and PHIS data were comparable in ma

119 ata, $1184336 for EMR data, and $2117522 for PHIS data.

120 Costs obtained from the PHIS database also showed reduction with CPG-directed ca

121 g data and pre-existing cost data within the PHIS database provided similar results.

122 the Pediatric Hospital Information Systems (PHIS) database, all normalized to patient census.

123 o the Pediatric Hospital Information System (PHIS) database.

124 tial acidification, but limits the extent of pHi decrease in neurons and astrocytes.

125 Calculation of psi and phi dihedral angles from the chemical shift assignments

126 The reaction of 3 with excess PhI displays striking kinetics which initially appears z

127 n in the 3 months after infection depends on PHI duration and testing frequency.

128 ngs reveal a previously unrecognized role of pHi dynamics for the differentiation of two distinct typ

129 Intracellular pH (pHi) dynamics is increasingly recognized as an important

130 ADCC was documented in 80% of PHI enrollment samples and in 100% of PHI 12-month, chro

131 f the high infectivity but short duration of PHI, even short-term behavior change can significantly r

132 e critical roles of Slc26a6 in regulation of pHi, excitability, and contractility.

133 The conductance versus axial magnetic flux Phi exhibits Aharonov-Bohm oscillations with maxima occu

134 However, the significance of increased pHi for cancer in vivo remains unresolved.

135 The estimated pre-harvest intervals (PHI) for fipronil and difenoconazole were 15 and 19.5day

136 ow pass filtering would "buffer" cancer cell pHi from non-steady-state extracellular pCO2.

137 The series exhibits quantum yields of up to phi = >4%, with emission maxima ranging from 725 to 820

138 Using a PHI>/=35, only 1/21 significant cancers was missed and 3

139 lumns form a 3D hexagonal crystalline phase, Phi(h)(k) (P6(3) symmetry), that can be obtained only fr

140 The highest order Phi(h)(k) consists of enantiopure single-handed columns

141 and a columnar hexagonal 2D liquid crystal, Phi(h).

142 Thus, ptxD/Phi has proven to be a very efficient, positive selectio

143 uman immunodeficiency virus (HIV) infection (PHI) have not been published.

144 c MRI (mpMRI) and the Prostate Health Index (PHI) have shown promise in predicting a positive biopsy

145 (-/-) mice to investigate the role of AE3 in pHi homeostasis in HC neurons, co-cultured with astrocyt

146 The effects of AE3 knockout on astrocytic pHi homeostasis in MAc-related assays require the presen

147 tumors require energy and intracellular pH (pHi) homeostasis through the activity of two major monoc

148 reaction of 1(P1) with N-nosyl iminoiodane (PhI horizontal lineNNs) 4(Ns) led to the formation of a

149 ato moieties, mediates nitrene-transfer from PhI horizontal lineNR sources to a wide variety of aliph

150 ents, Rx(3)Wx(3-8)PhixGxzetax(P/A) (motif A; Phi, hydrophobic; zeta, hydrophilic), (Y/W)PhiGSxT (moti

151 on and contraction; uncompensated changes in pHi impair cardiac function and trigger arrhythmia.

152 ffects has been unclear because the starting pHi in AE3(-/-) and wild-type neurons is indistinguishab

153 In agreement with previous studies, resting pHi in cultured astrocytes was 6.82 +/- 0.06 and inhibit

154 Drosophila Na(+)-H(+) exchanger DNhe2 lowers pHi in differentiating cells, impairs pFC differentiatio

155 In contrast, resting pHi in RON astrocytes was 7.10 +/- 0.04, significantly l

156 encoded biosensor we also confirm increased pHi in situ.

157 fusion, giving rise to an electric potential Phi in the 100 muV range on the micrometer scale.

158 We included patients enrolled during PHI in the Agence Nationale de Recherche sur le Sida PRI

159 tively enrolled 290 patients with documented PHI in the Zurich Primary HIV Infection Study.

160 between complement activation and neutrophil pHi In this article, we demonstrate that in vitro exposu

161 Still, the detection of phosphohistidine (pHis) in the proteome has remained difficult due to the

162 We show that pHi increases with differentiation from FSCs to prefolli

163 B and -C outward currents and NBCe1-mediated pHi increases, and changes in NBCe1 activity paralleled

164 n to Ru through I, rearrangement to a eta(2)-PhI intermediate, and Ph-I oxidative addition.

165 -assembly strategy to organize Mdh, Hps, and Phi into an engineered supramolecular enzyme complex usi

166 s to cells the ability to convert phosphite (Phi) into orthophosphate (Pi) offers an alternative sele

167 pHi is a critical regulator of other membrane and contra

168 We find that the stationary noise strength Phi is close to its baseline limit 1 when the mRNA level

169 Additionally, pHi is elevated in Slc26a6(-/)(-) cardiomyocytes with sl

170 Notably, increased pHi is now acknowledged as a conserved characteristic of

171 sophila melanogaster, we show that increased pHi is sufficient to induce dysplasia in the absence of

172 Intracellular pH (pHi) is critical to cardiac excitation and contraction;

173 report that an increase in intracellular pH (pHi) is necessary for the efficient differentiation of D

174 Histidine phosphorylation (pHis) is well studied in bacteria; however, its role in

175 ross-react with phosphotyrosine or the other pHis isomer.

176 ationic I(III) oxidants of the general form [PhI(L)2](2+) (L = pyridine, 4-DMAP, 4-cyanopyridine) all

177 If PHI lasts for 3 months and testing is performed monthly,

178 , AE3 contributes to braking the decrease in pHi later during MAc in both neurons and astrocytes.

179 can scan in the end-fire area (60 degrees < phi < 120 degrees , 45 degrees < theta < 80 degrees ), w

180 BPMA-PAAm gels in a reaction-limited regime (Phi << 0.15 for all measurements), allowing us to isolat

181 ate can lead to non-classical Phi(M)-values (Phi(M) > 1) in the rate-determining loop 1 substructure,

182 ngineering and report mutational Phi-values (Phi(M)) as indicators for folding transition-state struc

183 n the native-state can lead to non-classical Phi(M)-values (Phi(M) > 1) in the rate-determining loop

184 ect, and characterize anti-1-pHis and anti-3-pHis mAbs.

185 PHI manifested with typical ARS in 202 (70%) and with at

186 f amphiphile required to form microemulsion (Phi(ME)), which was the analytical signal of the method.

187 A simple taxonomy of Phi-measures is presented where they are each characteri

188 When requiring the Phi-measures to satisfy a minimum of attractive properti

189 Viridans group streptococcal detection using PHIS microbiology data had high sensitivity (92.3%) and

190 The high sensitivity and PPV of PHIS microbiology data suggest that using external data

191 Using regular and reverse-phi motion in a rapid adaptation paradigm, we investigat

192 At a threshold of >/=35, PHI + mpMRI demonstrated a NPV of 0.97 for excluding sig

193 ent iodine reagents of the general structure PhI[N(SO2R)(SO2R')]2 promote the selective direct C-H-am

194 ned model to evaluate the correction factor (Phi) needed for chamber SOA mass yields due to losses of

195 We measure an average nitrite quantum yield (Phi(NO2(-))) of (1.1 +/- 0.2)% (313 nm, 50 muM nitrate,

196 ike several Epac-specific antibodies tested, Phi-O-Me-cAMP exhibited dramatically reduced signals in

197 Phi-O-Me-cAMP is a weak partial agonist for purified Epa

198 Phi-O-Me-cAMP readily entered intact myocytes, but did n

199 Fluorescence of Phi-O-Me-cAMP was enhanced by binding to Epac.

200 -methyladenosine-3',5'-cyclic monophosphate (Phi-O-Me-cAMP) in mice lacking either one or both isofor

201 Reaction of 1-X with PhI(O2CCF3)2 facilitates I(-)/CF3CO2(-) ligand exchange

202 urylamines or thiophen-2-ylmethanamines with PhI(OAc)2 in the presence of the Pd(OAc)2 catalyst, succ

203 A N,N-ligand (1,10-Phen) and PhI(OAc)2 were identified as crucial factors to promote

204 Here, we use the common combination of PhI(OAc)2 with BF3.Et2O as a model to fully explore this

205 tructed from 2-(arylamino)benzamides through PhI(OAc)2-mediated oxidative C-N bond formation.

206 has been developed from ethynylcarbinols and PhI(OAc)2.

207 in self-assembled structures was found using PhI(OCOR)2.

208 and excellent correlation was found between Phi of 5a-g and sigmap(-) of the substituent on the phen

209 In experimental murine sepsis, pHi of blood neutrophils was analogously alkalinized, wh

210 No PHI of imidacloprid is required, while for oxamyl it was

211 ce of fluopyram at the pre-harvest interval (PHI) of 7-21 d was between 0.0108 and 0.1603 mg/kg, and

212 formation of peroxynitrite, corresponding to Phi(ONOO(-)) < 0.26%.

213 With moderate depletion of P at pHi or pH 6.5, CaP minerals became more prominent in the

214 ibodies (mAbs) that specifically recognize 1-pHis or 3-pHis; they do not cross-react with phosphotyro

215 hosphorylated, forming 1-phosphohistidine (1-pHis) or 3-phosphohistidine (3-pHis).

216 ze phosphorylation of nitrogens at the N1 (1-pHis) or N3 (3-pHis) positions of the imidazole ring, we

217 )2 (0-5 mol %) catalyzed hypervalent iodine [PhI(OTf)2] mediated oxidative coupling of 4-anilinoquina

218 1 complex in an inhibited state known as the phi-particle.

219 Samples from 14 healthy donors (HDs), 40 PHI patients, 17 Chronics, and 13 Elite controllers (ECs

220 c strategy based on mechanistic insight into pHis peptide gas-phase fragmentation during LC-MS/MS.

221 ins, combining selective immunoenrichment of pHis peptides and a bioinformatic strategy based on mech

222 n illustration of this strategy, we analyzed pHis peptides from glycerol-fed and mannitol-fed Escheri

223 c effect on net base uptake and steady-state pHi persisted only in vascular smooth muscle cells but n

224 al results, researchers have proposed that a phi (Phi)-clamp composed of phenylalanine (Phe)427 resid

225 able from that of a perfect electric mirror (phi = pi) to that of a perfect magnetic mirror (phi = 0)

226 ion of nitrogens at the N1 (1-pHis) or N3 (3-pHis) positions of the imidazole ring, we detect for the

227 mpared to an implementation using Intel Xeon Phi processor with off-chip memory (with hypothetical on

228 In contrast, increasing pHi promotes excess pFC cell differentiation toward a po

229 eport the first global proteomic analysis of pHis proteins, combining selective immunoenrichment of p

230 This study lays the groundwork for future pHis proteomics studies in bacteria and other organisms.

231 ation of the activation segment, measured by phi, psi, chi1, and pseudo-dihedral angles more accurate

232 opyranosyloxy)-3',4'-didehydro-1',2'-dihydro-phi,psi-caroten -2'-ol, is novel and has been given the

233 r MAc removal in neurons and astrocytes, and pHi recovery from an ammonium prepulse-induced acid load

234 neurons and astrocytes, and speeds neuronal pHi recovery from an ammonium prepulse-induced acid load

235 eases the acidification rate constant during pHi recovery from intracellular alkaline loads imposed b

236 Using ammonia pulse recovery, pHi recovery in RON astrocyte was achieved largely via V

237 s HCO3(-) efflux) enhances intracellular pH (pHi ) recovery (decrease) from alkali loads in neurons a

238 ellular enzyme in HCO3- transport, and hence pHi regulation in the heart.

239 genotypic influence on SLC4A7 expression and pHi regulation in vascular smooth muscle cells provides

240 degree upon V-ATPase for HCO3(-)-independent pHi regulation than do cultured astrocytes, with importa

241 eral ion transporters participate in cardiac pHi regulation.

242 astrocytes, contributes to intracellular pH (pHi ) regulation by facilitating the exchange of extrace

243 astrocytes, contributes to intracellular pH (pHi ) regulation by facilitating the exchange of extrace

244 sms of HCO3(-)-independent intracellular pH (pHi) regulation were examined in fibrous astrocytes with

245 two potential sorting motifs, YXXPhi (where Phi represents a bulky hydrophobic amino acid) and LL, t

246 and 0.90 (95% CI, 0.87-0.92) for %p2PSA and Phi respectively, and the specificity was low, only 0.09

247 and 0.17 (95% CI, 0.14-0.19) for %p2PSA and Phi, respectively.

248 ly after removal of plasma IgA from 12-month PHI samples: the magnitude of ADCC not only increased af

249 PHI scores were measured in men undergoing re-biopsy wit

250 to a membrane, whereas the poorly conserved phi segments play no role in binding or protection.

251 Under the ptxD/Phi selection, an average of 3.43 transgenic events per

252 pHi, suggesting that H155 is responsible for pHi sensitivity of Orai1/STIM1.

253 he molecular mechanism for intracellular pH (pHi) sensitivity of Orai1/STIM1 is not fully understood.

254 ase (Hps) and 6-phospho-3-hexuloseisomerase (Phi) serves as the key driving force to pull the pathway

255 ABAergic currents (EGABA) and NH4(+)-induced pHi shifts enabled an estimate of the range of chloride

256 ation mimics were created and NH4(+)-induced pHi shifts were used in cultured hippocampal neurons to

257 nsiderably in magnitude (from -0.02 to -1.00 pHi shifts) depending on the combination of alanine muta

258 known and a number of previously speculative pHis sites inferred by homology, predominantly in the ph

259 eadily integrate data collected in the 'fine phi-slicing' mode (in which the rotation angle per image

260 emains largely unexplored due to the lack of pHis-specific antibodies and the lability of the phospho

261 If Phi stays well above 1, then the gene is infrequently ac

262 ould be broadly useful for identification of pHis substrates and functional study of pHis using a var

263 minishes the response to acidic and alkaline pHi, suggesting that H155 is responsible for pHi sensiti

264 selection efficiency of 97% under the ptxD/Phi system.

265 free PSA (%p2PSA) and prostate health index (Phi) tests for PCa and to evaluate their ability in disc

266 it is crucial to understand the begin-state phi (the "self") - a state that is shaped by early socia

267 likewise exhibited a significantly increased pHi These data suggest a novel role for the anaphylatoxi

268 Abs) that specifically recognize 1-pHis or 3-pHis; they do not cross-react with phosphotyrosine or th

269 pared with the control (pHi 7.3), acidifying pHi to 6.3 or alkalinizing pHi to 8.3 and 8.8 caused sma

270 7.3), acidifying pHi to 6.3 or alkalinizing pHi to 8.3 and 8.8 caused small reductions in the open-t

271 In this study adding PHI to mpMRI improved overall and significant cancer pre

272 nflux, nor for maintaining intracellular pH (pHi) uniformity.

273 n of pHis substrates and functional study of pHis using a variety of immunological, proteomic, and bi

274 e functional effects of these residues using phi value analysis revealed a steep negative slope.

275 g of a hydrolysis-deficient mutant and apply Phi value analysis to compare timing of opening-associat

276 core include hydrogen-deuterium exchange and Phi-value analysis and can be expensive and time consumi

277 lding pathway of this protein we carry out a Phi-value analysis and use the resulting structural info

278 kinetics of a panel of mutants prepared for Phi-value analysis has now revealed a bimolecular reacti

279 Then, using Phi-value analysis we show that the structural differenc

280 Every phi-value was less than 0.4, indicating the transition s

281 Furthermore, the calculated PHI values, according to the maximum residue levels set

282 of human CFTR at different intracellular pH (pHi ) values.

283 degradation rates, the pre-harvest interval (PHI) values and the half-life values of the three pestic

284 th protein engineering and report mutational Phi-values (Phi(M)) as indicators for folding transition

285 The PHI was assessed for ability to add value to mpMRI in pr

286 ctivity, acid loading from a highly alkaline pHi was rate-limited by HCO3(-) supply from spontaneous

287 ing highly infectious primary HIV infection (PHI), we developed a stochastic individual-based model t

288 ity is highly dependent on intracellular pH (pHi), we propose a direct mechanistic link between compl

289 Okra samples harvested after the estimated PHIs were found safe for human consumption.

290 Both permeability and intracellular pH (pHi) were found to be significantly improved for 14 comp

291 were studied and the pre-harvest intervals (PHIs) were calculated.

292 rt limitations, we employed Weisz's modulus (Phi), which compares observed enzyme-catalyzed reaction

293 red sequences derived from the bacteriophage phi X 174 genome.

294 h, which can be unambiguously aligned to the phi X 174 reference genome, and demonstrate proof-of-con

295 ermore, we show nanopore sequencing reads of phi X 174 up to 4,500 bases in length, which can be unam

296 f DNA from two viruses (Human adenovirus 41, Phi X 174) and the bacterium Enterococcus faecalis, whic

297 t of detection (LOD) determined for HAdV 41, Phi X 174, and E. faecalis was 35 GU/muL, 1 GU/muL, and

298 ic tail of each cargo, with Wls using tandem Phi-X-[L/M] motifs and beta2AR using a PDZ motif.

299 We identified a common D-Q-Phi-X0,1-G-K-N-zeta-E motif in CsgC client proteins that

300 uman immunodeficiency virus (HIV) infection (PHI) yields a larger decrease in cell-associated HIV-DNA