ライフサイエンスコーパス: phobia

1 for deficits in fear extinction (e.g. PTSD, phobias).

2 der), psychosis-spectrum symptoms, and fear (phobias).

3 ngitudinal fMRI studies of adolescent social phobia.

4 rocessing also manifest in adolescent social phobia.

5 ially affects response in generalized social phobia.

6 stimuli more generally in generalized social phobia.

7 er, generalized anxiety disorder, and social phobia.

8 ns among extraversion, neuroticism, and each phobia.

9 ocial phobia and agoraphobia, but not animal phobia.

10 c disorders, including depression and social phobia.

11 s, phobic postural vertigo, and space-motion phobia.

12 d posttraumatic stress disorder and specific phobia.

13 current anxiety disorder, excluding specific phobia.

14 epression, generalized anxiety disorder, and phobia.

15 ding most strongly on animal and situational phobia.

16 premenstrual dysphoric disorder, and social phobia.

17 cts of SSRI treatment for generalized social phobia.

18 an impact on risk for agoraphobia and social phobia.

19 ically referred for an evaluation for social phobia.

20 specific functional impairment due to social phobia.

21 en trial of nine patients with DSM-IV social phobia.

22 r, avoidance, and overall severity of dental phobia.

23 f striatal activation may manifest in social phobia.

24 behavioral inhibition and adolescent social phobia.

25 ing fear-related disorders, such as PTSD and phobias.

26 eralized-agoraphobic anxiety vs the specific phobias.

27 he second loaded primarily in the 2 specific phobias.

28 ignificant for all disorders except specific phobias.

29 ional model for the acquisition of fears and phobias.

30 y were supported by analyzing both fears and phobias.

31 not distinct from those of the more typical phobias.

32 ials have only examined adults with specific phobias.

33 ts with social anxiety disorder and specific phobias.

34 introversion, 1.36 (95% CI 1.10 to 1.68) for phobia, 1.42 (95% CI 1.14 to 1.76) for manifest anxiety,

35 der (22%), social phobia (17%), and specific phobia (15%).

36 rtion of the genetic risk factors for animal phobia (16%) was shared with those that influence person

37 agoraphobia or panic disorder (22%), social phobia (17%), and specific phobia (15%).

38 8 medication-free adolescents-14 with social phobia, 18 with generalized anxiety disorder but not soc

39 MDD (47%), specific phobia (24%), panic disorder (16%), obsessive-compulsive

40 39 medication-free participants with social phobia (25 adults and 14 adolescents) and 39 healthy com

41 3.3% vs. 11.5%, Z=-3.13, p<0.001) and social phobias (3.9% vs. 9.7%, Z=2.38, p<0.05) were significant

42 (9.3%), specific phobias (8.8%), and social phobia (6.6%).

43 Among those with DSM-IV social phobia (7.2%), classification based on number (normally

44 entiles) of age-of-onset is much earlier for phobias (7-14, IQR 4-20) and impulse-control disorders (

45 sorders were panic disorder (9.3%), specific phobias (8.8%), and social phobia (6.6%).

46 r panic disorder, 12.6% vs. 25.3% for social phobia, 9.1% vs. 25.9% for alcohol abuse or dependence,

47 g abuse, 97.6 [0.64]; P = .02), and specific phobia (97.1 [0.39]; P = .001) after adjustment for a wi

48 o associated with risk for adolescent social phobia, a similar pattern of striatal activation may man

49 lts for models of relapse and treatments for phobias, addiction, and overeating are discussed.

50 ety disorder (GAD), panic disorder (PD), and phobias (agoraphobia, social phobia, etc.).

51 environmental risk for three phobias (social phobia, agoraphobia, and animal phobia) in twins ascerta

52 on anxiety disorder, social phobia, specific phobia, agoraphobia, and obsessive-compulsive disorder,

53 on anxiety disorder, social phobia, specific phobia, agoraphobia, and obsessive-compulsive disorder;

54 or depression, generalized anxiety disorder, phobia, alcohol dependence, drug abuse/dependence, adult

55 in later adult age groups for manic episode, phobias, alcohol use disorders, and generalized anxiety

56 Ten subjects with specific phobia and 10 healthy comparison subjects were studied b

57 Sixteen patients with generalized social phobia and 16 healthy comparison subjects group-matched

58 indices for persons with and without social phobia and adjusted where indicated for the effects of m

59 All of the genetic risk factors for social phobia and agoraphobia were shared with those that influ

60 egative between extraversion and both social phobia and agoraphobia, and that between extraversion an

61 positive between neuroticism and both social phobia and agoraphobia, and that between neuroticism and

62 entirely for the genetic liability to social phobia and agoraphobia, but not animal phobia.

63 single and multiple phobias within principal phobia and comparing these with nonprincipal phobia reve

64 ocial phobia, depression, or comorbid social phobia and depression.

65 bia, depressive disorder, or comorbid social phobia and depressive disorder and 44 healthy comparison

66 to facial expressions in generalized social phobia and generalized anxiety disorder.

67 ry dysfunctions differ in generalized social phobia and generalized anxiety disorder.

68 interacted to predict new onset of specific phobia and generalized anxiety disorder.

69 or binding potential in patients with social phobia and healthy comparison subjects.

70 sessed among individuals with DSM-III social phobia and individuals with subclinical social phobia (i

71 ences in favor of CBT for measures of social phobia and interpersonal problems, but not for depressio

72 nd depression interacted to predict specific phobia and major depressive disorder.

73 unmedicated subjects with generalized social phobia and no significant lifetime psychiatric comorbidi

74 Specific phobia and obsessive compulsive disorder were the most i

75 Specific phobia and obsessive-compulsive disorder (internalizing)

76 tients with anxiety disorders such as social phobia and posttraumatic stress disorder (PTSD).

77 ns such as toilet training, which diminishes phobia and provides positive reinforcement through a rew

78 understanding of the relationship of social phobia and risk for alcohol conditions, which may have i

79 was used to assess the association of social phobia and subclinical social phobia with incident alcoh

80 and syringes that avoids the issue of needle phobia and the risk of needle-stick injury.

81 Patients with TCS phobia and the sources from which patients are receiving

82 Investigate the extent of fever phobia and to explore potential associations with time,

83 tic stress disorder, social phobia, specific phobias and generalized anxiety disorder--these response

84 disrupted in psychiatric disorders, such as phobias and obsessive-compulsive disorder.

85 anism may partly explain the heritability of phobias and other complex traits.

86 Lifetime phobias and personality traits were assessed through dia

87 s of individual differences in the risks for phobias and their associated irrational fears in male tw

88 fic, play a moderate role in the etiology of phobias and their associated irrational fears.

89 ) were searched using the terms 'fever' and 'phobia'; and 'fever phobia' as a free text term.

90 generalized anxiety disorder but not social phobia, and 26 with no psychiatric disorder-matched on s

91 healthy adolescents, adolescents with social phobia, and adolescents with generalized anxiety disorde

92 disease therapy, ataxia, depression, social phobia, and behaviour disturbances following brain injur

93 chiatric comorbidity (panic disorder, social phobia, and drug dependence), disability and restricted

94 er (PTSD), social anxiety disorder, specific phobia, and fear conditioning in healthy individuals wer

95 ed the onset of OCD, social phobia, specific phobia, and generalized anxiety disorder in childhood, b

96 ons between AUD and panic disorder, specific phobia, and generalized anxiety disorder were modest (od

97 scales (psychasthenia, social introversion, phobia, and manifest anxiety) and an overall anxiety fac

98 a, social phobia, animal phobia, situational phobia, and neuroticism were assessed in over 9,000 twin

99 sorders, panic disorder, agoraphobia, social phobia, and obsessive-compulsive disorder.

100 disorder, social anxiety disorder, specific phobia, and panic disorder.

101 ife for patients with panic disorder, social phobia, and posttraumatic stress disorder.

102 disorder, agoraphobia, social phobia, animal phobia, and situational phobia) were obtained during per

103 emispheric asymmetries of function in social phobia, and the influence of comorbidity with depressive

104 relationships; these include autism, social phobia, and the personality disorders.

105 independently predicted new onset of social phobia, and the two interacted to predict new onset of s

106 taneous absorption, adverse affects, steroid phobia, and treatment compliance.

107 s, and anxiety disorders other than specific phobia, and was positively associated with past-year maj

108 sorder, generalized anxiety disorder, social phobia, and/or posttraumatic stress disorder (with or wi

109 anic disorder, generalized anxiety disorder, phobias, and obsessive-compulsive disorder (OCD) to expl

110 anic disorder, generalized anxiety disorder, phobias, and OCD all have significant familial aggregati

111 correlations between personality traits and phobias, and unique environmental correlations were rela

112 isorder, panic disorder, agoraphobia, social phobia, animal phobia, and situational phobia) were obta

113 isorder, panic disorder, agoraphobia, social phobia, animal phobia, situational phobia, and neurotici

114 c, or posttraumatic stress disorders; social phobia; anxious or melancholic features; or more severe

115 Features of TCS phobia are commonly reported by patients across cultures

116 ditions such as anxiety, autism, stress, and phobias are thought to be linked to its abnormal functio

117 Several anxiety disorders, including social phobia, are genetically influenced.

118 ), namely generalized AD, panic disorder and phobias, are common, etiologically complex conditions wi

119 t extent indices were attributable to social phobia as opposed to comorbid major depression.

120 ocial, animal, situational, and blood/injury phobias as well as their associated irrational fears.

121 g the terms 'fever' and 'phobia'; and 'fever phobia' as a free text term.

122 the patients who met diagnostic criteria for phobia at baseline, fewer patients in the immediate trea

123 dividuals with a DSM-III diagnosis of social phobia at baseline, only one developed heavy drinking by

124 group continued to meet criteria for dental phobia at follow-up as compared with the wait-list group

125 y control, which may secondarily lead to the phobia because of repeated syncopal events.

126 e of generalized anxiety disorder and social phobia but not panic disorder, suggesting that PersDs ha

127 th specific phobia had histories of juvenile phobias but not other anxiety disorders.

128 Social phobia can be a serious, disabling anxiety disorder asso

129 , an abnormal fear of heights, is a specific phobia characterized as apprehension cued by the occurre

130 e role of genetic factors in the etiology of phobias comes from one population-based sample of female

131 cognitive processing in patients with social phobia, depression, or comorbid social phobia and depres

132 otal of 125 unmedicated patients with social phobia, depressive disorder, or comorbid social phobia a

133 on in the striatum of subjects with specific phobia does not significantly differ from that of normal

134 The neural correlates of adult social phobia during face processing also manifest in adolescen

135 hether the neural correlates of adult social phobia during face processing also manifest in adolescen

136 maladaptive, as in anxiety disorders such as phobias (e.g., avoiding air transportation) and social a

137 terview-Version 2.1 module for DSM-IV social phobia, enhanced with 6 additional (for a total of 12) s

138 order (PD), and phobias (agoraphobia, social phobia, etc.).

139 Most subjects with blood/injury phobia experience syncope or presyncope as part of the p

140 Evidence for linkage to social phobia for chromosome 16 markers was identified.

141 other white women (P = 0.00009 for specific phobia; for all other values P = 0.00001).

142 rther, as more disorders supplanted specific phobia from principal disorder, overall defensive mobili

143 sorder, agoraphobia, specific phobia, social phobia, generalized anxiety disorder, posttraumatic stre

144 57 probands with an anxiety disorder (social phobia, generalized anxiety disorder, separation anxiety

145 disorder, social anxiety disorder, specific phobias, generalized anxiety disorder, or separation anx

146 five were "internalizing" (major depression, phobias, generalized anxiety disorder, panic disorder, a

147 , generalized anxiety disorder, and probably phobias, genes largely explain this familial aggregation

148 studies that compared nonadherence between a phobia group and a nonphobia group, patients in both pho

149 Within the social phobia group, there was a nonsignificant correlation of

150 relative to the healthy comparison or social phobia group.

151 roup and a nonphobia group, patients in both phobia groups were found to have a significantly higher

152 Generalized social phobia (GSP) and generalized anxiety disorder (GAD) are

153 Generalized social phobia (GSP) is characterized by fear of social interact

154 Generalized social phobia (GSP) is characterized by fear/avoidance of socia

155 Generalized social phobia (gSP), also known as generalized social anxiety d

156 Adults with specific phobia had histories of juvenile phobias but not other a

157 Overall, the authors found that women with phobias had better outcomes and that men with psychiatri

158 ocial anxiety disorder (also known as social phobia) has moved from rudimentary awareness that it is

159 ubjects with syncope related to blood/injury phobia have an underlying autonomic dysregulation predis

160 ty-related disorders exemplified by specific phobia, have an emotional learning component to them tha

161 Patients with generalized social phobia, however, showed significantly increased response

162 functional impairment attributable to social phobia in a community sample, and (2) to verify the exis

163 While social phobia in adolescence predicts the illness in adulthood,

164 ctly compared the neural responses in social phobia in adults and adolescents.

165 ns, and effect on treatment adherence of TCS phobia in atopic dermatitis.

166 Social phobia in clinical studies is vividly associated with ex

167 yal of the impairment associated with social phobia in community samples.

168 t pathophysiological mechanisms for specific phobia in contrast to OCD, in which deficient striatal r

169 r, avoidance, and overall severity of dental phobia in favor of immediate treatment at the follow-up

170 and quick scale for assessing corticosteroid phobia in Japanese atopic dermatitis patients.

171 Included articles must have assessed TCS phobia in patients with atopic dermatitis or their careg

172 fficulty experienced by patients with social phobia in social situations.

173 Rather, social phobia in the community seems to exist on a continuum of

174 bias (social phobia, agoraphobia, and animal phobia) in twins ascertained from a large, population-ba

175 ng in subjects with and without small animal phobia, in a follow-up to analogous studies of obsessive

176 Questionnaires used to assess for TCS phobia included 1 to 69 questions.

177 Phobia interacted with alcohol use disorders in nonblack

178 ne treatment at weeks 1 and 2 for the Social Phobia Inventory (P < .05 for all).

179 he Liebowitz Social Anxiety Scale and Social Phobia Inventory and at week 2 and weeks 6 through 12 fo

180 iebowitz Social Anxiety Scale and the Social Phobia Inventory scores were compared across the two cro

181 al Impression-Severity of Illness and Social Phobia Inventory scores.

182 on-Severity of Illness scale, and the Social Phobia Inventory, and at weeks 4 through 12 for response

183 Disorder Severity-Self-report Scale, Social Phobia Inventory, and PTSD Checklist-Civilian Version sc

184 Generalized social phobia involves fear/avoidance, specifically of social s

185 obia and individuals with subclinical social phobia (irrational fear of social situations without sig

186 Social phobia is a common, sometimes disabling, fear of situati

187 Fever phobia is a term that has been used to describe the exag

188 e results support the hypothesis that social phobia is associated with dysfunction of left hemisphere

189 Social phobia is associated with substantial impairment in mult

190 Fever phobia is common and has not significantly declined over

191 Generalized social phobia is common, persistent, and disabling and is often

192 ated responsivity characteristic of specific phobia is limited to those patients for whom circumscrib

193 An actual example relating psychosis to phobia is presented to show the bias that can result and

194 Impairment in social phobia is substantial, even in the absence of comorbid m

195 As specific phobia is superseded in severity by broad and chronic ne

196 s, which postulate that the vulnerability to phobias is largely innate and does not arise directly fr

197 The genetic liability to blood/injury phobias is not distinct from those of the more typical p

198 increased inflammation in PTSD, GAD, PD, and phobias is via the activation of the stress response and

199 nxiety disorder (SAD) (also known as "social phobia") is frequently comorbid with major depression, a

200 in posttraumatic stress disorder or specific phobias, is also socially transmitted to children and is

201 ding of exaggerated responsivity in specific phobia-its physiology and neural mediators-has advanced

202 s associated with increased risks for social phobia, major depression, disruptive behavior disorders,

203 sorder, generalized anxiety disorder, social phobia, major depression, dysthymic disorder, and/or min

204 raumatic stress disorder, panic disorder and phobia manifest in ways that are consistent with an unco

205 Generalized social phobia may be associated with low binding of [(123)I]IBZ

206 correlates that are observed in adult social phobia may represent the persistence of profiles establi

207 Despite this 'steroid phobia', multiple studies indicate that proper use of gl

208 Treatment-seeking individuals with social phobia (N = 40) were asked to give two impromptu speeche

209 A community sample of specific phobia (n = 74 principal; n = 86 nonprincipal) and contr

210 sive disorder (OCD) (N=277 [41%]) and social phobia (N=134 [20%]).

211 n the sham group), and syncope due to needle phobia (n=1; in the sham group).

212 che, he experienced photo-, phono- and odour-phobia, nausea and vomiting, worsening of the headache b

213 luded depression, dysthymia, anxiety, panic, phobia, obsession, compulsion, posttraumatic, care manag

214 alized anxiety disorder, agoraphobia, social phobia, obsessive-compulsive disorder, anorexia, or subs

215 , probably due to several factors, including phobia of opioids, under-reporting by patients, and unde

216 e suggestive results obtained by analysis of phobias only were supported by analyzing both fears and

217 Social anxiety disorder (social phobia or avoidant disorder) was significantly more like

218 e association between A2AR polymorphisms and phobia or panic attacks in humans and prompts a therapeu

219 lacebo than patients with generalized social phobia or panic disorder.

220 2.30, relative to respondents without social phobia or subclinical social fears.

221 der (OR, 1.3; 95% CI, 1.06-1.59), and social phobia (OR, 1.3; 95% CI, 1.09-1.64).

222 s with obsessive-compulsive disorder, social phobia, or panic disorder who received placebo in three

223 ts with generalized anxiety disorder, social phobia, or panic disorder.

224 orders (generalized anxiety disorder, social phobia, panic disorder, and posttraumatic stress disorde

225 iety disorder (ie, major depressive episode, phobias, panic, generalized anxiety disorder, and obsess

226 Principal specific phobia patients far exceeded control participants in sta

227 egions, both the adolescent and adult social phobia patients showed significantly increased BOLD resp

228 zed) in patients with panic disorder, social phobia, posttraumatic stress disorder, generalized anxie

229 torial design in which one factor was social phobia (present versus absent) and the second factor was

230 n symptoms of generalized anxiety and social phobia prior to participating in a neuroimaging visit.

231 onality trait of neuroticism--as an index of phobia-proneness--and the lifetime histories of 5 phobia

232 e, psychoses, obsessive compulsive disorder, phobias, psychopathic behaviour, depression and anxiety.

233 In a clinical trial, patients with height phobia received two sessions involving 30 minutes of vir

234 Topical corticosteroid (TCS) phobia refers to the negative feelings and beliefs relat

235 notypic evidence that prominence of specific phobia relative to co-occurring conditions (i.e., princi

236 g magnitudes characterizes adolescent social phobia, relative to activation in this region in adolesc

237 remission, a 39% lower likelihood of social phobia remission, and no difference in likelihood of pan

238 D predicted a 41% lower likelihood of social phobia remission.

239 ally, reflecting elevated generalized social phobia responses in these regions to all event types.

240 phobia and comparing these with nonprincipal phobia revealed a continuum of decreasing defensive mobi

241 ysiological candidate for influencing social phobia risk.

242 On the Brief Social Phobia Scale, all active treatments were superior to PBO

243 of separation anxiety disorder and specific phobia, severe role impairment, and suicidality.

244 ncreasing magnitude, adolescents with social phobia showed increasingly heightened caudate and putame

245 , general externalizing behaviors and animal phobia showing how human decisions can inhibit the expre

246 disorder, agoraphobia, social phobia, animal phobia, situational phobia, and neuroticism were assesse

247 the genetic and environmental risk for three phobias (social phobia, agoraphobia, and animal phobia)

248 ucted in humans diagnosed as having specific phobia, social anxiety disorder, panic disorder with or

249 rders (panic disorder, agoraphobia, specific phobia, social phobia, generalized anxiety disorder, pos

250 anxiety disorder, selective mutism, specific phobias, social anxiety disorder, panic disorder, agorap

251 isorder, separation anxiety disorder, social phobia, specific phobia, agoraphobia, and obsessive-comp

252 isorder, separation anxiety disorder, social phobia, specific phobia, agoraphobia, and obsessive-comp

253 rticipants reported the onset of OCD, social phobia, specific phobia, and generalized anxiety disorde

254 rder, post-traumatic stress disorder, social phobia, specific phobias and generalized anxiety disorde

255 in the pathophysiology of generalized social phobia, specifically through its involvement in distorte

256 n and generalized anxiety) and fear factors (phobia subscales).

257 a-proneness--and the lifetime histories of 5 phobia subtypes (agoraphobia, social, animal, situationa

258 All 5 phobia subtypes aggregate within twin-pairs.

259 e, and (2) to verify the existence of social phobia subtypes in the community, and report on their re

260 reliability and differed meaningfully across phobia subtypes.

261 mon therapeutic method for treating specific phobias such as fear of dental injections, lack of acces

262 rning, and early clinical data with specific phobias suggest that the treatment effects of exposure t

263 is association broadened to panic and social phobia symptoms in adolescence (r = 0.17-0.24 and r = 0.

264 0 min) and placebo (normal saline) on social phobia symptoms.

265 rved in social anxiety disorder and specific phobia than in PTSD.

266 nificantly lower in the subjects with social phobia than in the comparison subjects.

267 We evaluated for phobias the prediction of the stress-diathesis model tha

268 viduals with a history of subclinical social phobia, the cumulative incidence rates of heavy drinking

269 For example, among adolescents with specific phobia, those with severe disorder had a mean (SE) of 4.

270 nd psychiatric disorders ranging from social phobia to autism.

271 ssions in adults and adolescents with social phobia to determine whether the neural correlates of adu

272 ntly more likely than persons without social phobia to rate themselves as "low functioning" on the Qu

273 der, generalized anxiety disorder, or social phobia to receive 14 sessions of cognitive behavioral th

274 nomenclature and assessment methods for TCS phobia used in studies, however, lack standardization, p

275 ng among respondents with subclinical social phobia was 2.41, and the estimated relative risk for alc

276 There was significant variation in how phobia was defined, ranging from concern to irrational f

277 ia, and that between extraversion and animal phobia was effectively zero.

278 Social phobia was intermediate in that it was influenced by bot

279 bia, and that between neuroticism and animal phobia was moderate.

280 In addition, the severity of social phobia was significantly correlated with the enhanced ro

281 (SSRIs) in patients with generalized social phobia was tested.

282 Identifying loci for social phobia was the goal of this study.

283 f their mode of acquisition, (2) the risk of phobias was not decreased in co-twins of twins who had s

284 esis model was confirmatory: (1) the risk of phobias was not elevated in co-twins of twins who had no

285 tric (Zlr score) linkage analyses for social phobia were completed with Allegro and Genehunter X soft

286 Persons with social phobia were impaired on a broad spectrum of measures, ra

287 ng a primary diagnosis of generalized social phobia were recruited via advertisement.

288 Phobias were elevated in all at-risk groups, and depress

289 ocial phobia, animal phobia, and situational phobia) were obtained during personal interviews from a

290 ables, compared with subjects without social phobia, whereas no difference between groups was found i

291 e neural underpinnings of generalized social phobia, which is defined by a persistent heightened fear

292 with the traditional etiologic theories for phobias, which assume conditioning or social transmissio

293 status than outcomes among women, except for phobias, which predicted a better outcome among women.

294 cts were 14 patients with generalized social phobia who were less than "very much improved" on the Cl

295 tion of social phobia and subclinical social phobia with incident alcohol abuse/dependence and incide

296 Patients with social phobia with or without a comorbid depressive disorder ha

297 Distinguishing between single and multiple phobias within principal phobia and comparing these with

298 age, IQ, and gender with generalized social phobia without generalized anxiety disorder (N=17), gene

299 The patients with generalized social phobia without generalized anxiety disorder showed incre

300 anxiety in patients with generalized social phobia without generalized anxiety disorder.