ライフサイエンスコーパス: phosphatase and tensin homolog

1 eurin inhibitors and with high expression of phosphatase and tensin homolog.

2 , activating transcription factor; and PTEN, phosphatase and tensin homolog.

3 titutively active GSK3beta(S9A) or wild-type phosphatase and tensin homolog.

4 thione, where it functions as a cofactor for phosphatase and tensin homolog.

5 Deletion of PTEN (phosphatase and tensin homolog), a negative regulator of

6 etry demonstrated an increased expression of phosphatase and tensin homolog, a negative regulator of

7 We identified phosphatase and tensin homolog, a tumor suppressor, as a

8 mice showed increased splenic apoptosis and phosphatase and tensin homolog activation and decreased

9 nase), a scaffold protein required for PTEN (phosphatase and tensin homolog) activity, is a direct ta

10 extracellular signal-regulated kinases 1/2, phosphatase and tensin homolog, adenosine monophosphate-

11 hibition, using small-molecule inhibitors or phosphatase and tensin homolog adenovirus, led to decrea

12 as well as the phosphatidylinositol 3-kinase/phosphatase and tensin homolog/AKT, retinoblastoma/cycli

13 ivation of RARbeta in the neuron inactivates phosphatase and tensin homolog and induces its transfer

14 RNAs in increased cell proliferation through phosphatase and tensin homolog and phosphoinositide 3-ki

15 induces the posttranslational degradation of phosphatase and tensin homolog and the activation of the

16 g many dual-specificity phosphatases such as phosphatase and tensin homolog and vaccinia H1-related p

17 1 regulates the expression of PTEN (encoding phosphatase and tensin homolog) and the activity of the

18 N-induced putative kinase protein 1; PTEN is phosphatase and tensin homolog) and the cytosolic ubiqui

19 e-treatment tumour, had a copy loss of PTEN (phosphatase and tensin homolog) and those lesions that b

20 x O1, protein-tyrosine phosphatase-1B, PTEN (phosphatase and tensin homolog), and p85 phosphatidylino

21 Similar changes in SIRT1, phosphatase and tensin homolog, and Akt were also noted

22 erosis complex 1 and 2, neurofibromatosis 1, phosphatase and tensin homolog, and potentially Rett syn

23 utations in the tumour suppressor gene PTEN (phosphatase and tensin homolog) are frequent events and

24 regulation of the inositol phosphatase PTEN (phosphatase and tensin homolog) as primarily responsible

25 Mechanistically, we identified Pten (phosphatase and tensin homolog) as the functionally impo

26 Knockdown of phosphatase and tensin homolog by small interfering RNA

27 gression and are negatively regulated by the phosphatase and tensin homolog DAF-18/PTEN.

28 different ligands in brain, including PTEN (phosphatase and tensin homolog), dasm1 (dendrite arboriz

29 prostate carcinoma in vivo in the context of phosphatase and tensin homolog deficiency.

30 nd delayed prostate tumor involution both in phosphatase and tensin homolog-deficient (PTEN-deficient

31 The activation of beta-catenin inhibited phosphatase and tensin homolog delete on chromosome 10 (

32 mouse model is generated by the ablation of phosphatase and tensin homolog deleted from chromosome 1

33 [phosphatidylinositol (3,4,5)-trisphosphate phosphatase and tensin homolog deleted from chromosome 1

34 ed reduction of the tumor suppressor protein phosphatase and tensin homolog deleted in chromosome 10

35 ot analyses showed that the loss of LKB1 and phosphatase and tensin homolog deleted on chromosome 10

36 Phosphatase and tensin homolog deleted on chromosome 10

37 or in prostate stem cells, we found that the phosphatase and tensin homolog deleted on chromosome 10

38 Phosphatase and tensin homolog deleted on chromosome 10

39 iogenesis, is up-regulated in the absence of phosphatase and tensin homolog deleted on chromosome 10

40 ed by its repression of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10

41 The phosphatase and tensin homolog deleted on chromosome 10

42 Levels of phosphatase and tensin homolog deleted on chromosome 10

43 The Phosphatase And Tensin Homolog Deleted On Chromosome 10

44 Here we demonstrate that the phosphatase and tensin homolog deleted on chromosome 10

45 Tuberous sclerosis complex 2 (TSC2) and phosphatase and tensin homolog deleted on chromosome 10

46 The phosphatase and tensin homolog deleted on chromosome 10

47 a manner that was not apparently affected by phosphatase and tensin homolog deleted on chromosome 10

48 phosphatase and tensin homolog deleted on chromosome 10

49 n this study, we report that the activity of phosphatase and tensin homolog deleted on chromosome 10

50 4,5)-trisphosphate signaling with a specific phosphatase and tensin homolog deleted on chromosome 10

51 ereas the negative regulator of the pathway, phosphatase and tensin homolog deleted on chromosome 10

52 as human glioma lines, we show that loss of phosphatase and tensin homolog deleted on chromosome 10

53 Down-regulation of phosphatase and tensin homolog deleted on chromosome 10

54 Mutations in the tumor-suppressor gene phosphatase and tensin homolog deleted on chromosome 10

55 er that inactivation of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10

56 ease in the levels of phosphorylated p38 and phosphatase and tensin homolog deleted on chromosome 10

57 ents with heterozygous germline mutations in phosphatase and tensin homolog deleted on chromosome 10

58 Phosphatase and tensin homolog deleted on chromosome 10

59 The phosphatase and tensin homolog deleted on chromosome 10

60 The dual-function phosphatase and tensin homolog deleted on chromosome 10

61 to oleate elevated the protein level of the phosphatase and tensin homolog deleted on chromosome 10

62 Expression of phosphatase and tensin homolog deleted on chromosome 10

63 d phosphorylation/inactivation of myocardial phosphatase and tensin homolog deleted on chromosome 10

64 Phosphatase and tensin homolog deleted on chromosome 10

65 By specifically inhibiting the phosphatase and tensin homolog deleted on chromosome 10

66 tation, expression of ERBB1 vIII, or loss of phosphatase and tensin homolog deleted on chromosome 10

67 1 modulates gemcitabine-induced apoptosis by phosphatase and tensin homolog deleted on chromosome 10

68 Phosphatase and tensin homolog deleted on chromosome 10

69 Recent studies suggest that the phosphatase and tensin homolog deleted on chromosome 10

70 aining inositol 5'-phosphatase 2 (SHIP2) and phosphatase and tensin homolog deleted on chromosome 10

71 nase-1 (PDK1) and is negatively regulated by phosphatase and tensin homolog deleted on chromosome 10

72 increases the amount of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10

73 GH excess leads to decreased colon cell phosphatase and tensin homolog deleted on chromosome 10

74 PINK1 (phosphatase and tensin homolog deleted on chromosome 10

75 Phosphatase and tensin homolog deleted on chromosome 10

76 (bright) NK cells express significantly more phosphatase and tensin homolog deleted on chromosome 10

77 und that expression of the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10

78 The dual-specificity phosphatase and tensin homolog deleted on chromosome 10

79 Mutation or deletion of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10

80 Mutations in phosphatase and tensin homolog deleted on chromosome 10

81 Tumor-suppressor genes phosphatase and tensin homolog deleted on chromosome 10

82 The tumor-suppressor, phosphatase and tensin homolog deleted on chromosome 10

83 onylation of the lipid phosphatase known as "phosphatase and tensin homolog deleted on chromosome 10"

84 We investigated the role of PTEN (phosphatase and tensin homolog deleted on chromosome 10)

85 The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10)

86 y of disrupting the ASD candidate gene PTEN (phosphatase and tensin homolog deleted on chromosome 10)

87 Loss of the tumor suppressor Pten (phosphatase and tensin homolog deleted on chromosome 10)

88 Somatic and germline mutations in PTEN (phosphatase and tensin homolog deleted on chromosome 10)

89 Here, we demonstrate that the PTEN (phosphatase and tensin homolog deleted on chromosome 10)

90 The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10)

91 PTEN (phosphatase and tensin homolog deleted on chromosome 10)

92 PTEN (phosphatase and tensin homolog deleted on chromosome 10)

93 The PTEN (phosphatase and tensin homolog deleted on chromosome 10)

94 PTEN (phosphatase and tensin homolog deleted on chromosome 10)

95 PTEN (phosphatase and tensin homolog deleted on chromosome 10)

96 s of different in vitro ages; however, PTEN (phosphatase and tensin homolog deleted on chromosome 10)

97 Germline mutations of PTEN (phosphatase and tensin homolog deleted on chromosome 10)

98 Deficiency in PTEN (phosphatase and tensin homolog deleted on chromosome 10)

99 eted deletion of the lipid phosphatase PTEN (phosphatase and tensin homolog deleted on chromosome 10)

100 We investigated PTEN (phosphatase and tensin homolog deleted on chromosome 10)

101 PTEN (phosphatase and tensin homolog deleted on chromosome 10)

102 Upregulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10)

103 regulated by the inositol phosphatases PTEN (phosphatase and tensin homolog deleted on chromosome 10)

104 addition, we show that the phosphoinositide phosphatase and tensin homolog deleted on chromosome 10,

105 T cells inversely correlated with levels of phosphatase and tensin homolog deleted on chromosome 10.

106 Phosphatase and tensin homolog deleted on chromosome ten

107 e report that nuclear translocation of PTEN (phosphatase and tensin homolog deleted on chromosome TEN

108 Phosphatase and tensin homolog deleted on chromosome ten

109 Phosphatase and tensin homolog deleted on chromosome ten

110 PTEN (phosphatase and tensin homolog deleted on chromosome ten

111 Germline mutations in the gene encoding phosphatase and tensin homolog deleted on chromosome ten

112 ar level, chronic morphine induced the PTEN (phosphatase and tensin homolog deleted on chromosome Ten

113 ways, all of which result in upregulation of phosphatase and tensin homolog deleted on chromosome ten

114 Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten

115 1/MDA-6) (p21) and the tumor suppressor gene phosphatase and tensin homolog deleted on chromosome ten

116 p53 is sufficient for it to induce the PTEN (phosphatase and tensin homolog deleted on chromosome ten

117 (RNAi) knockdown of lipid phosphatase PTEN (phosphatase and tensin homolog deleted on chromosome Ten

118 catenin activation in association with PTEN (phosphatase and tensin homolog deleted on chromosome ten

119 Phosphatase and tensin-homolog deleted on chromosome 10

120 (p75NTR) signaling or its downstream target phosphatase-and-tensin-homolog-deleted-on-chromosome-10

121 toma RAS viral (v-ras) oncogene homolog, and phosphatase and tensin homolog, demonstrating PHIP activ

122 cAMP and deletion of the gene encoding pten (phosphatase and tensin homolog), enables RGCs to regener

123 eficient endothelial cells exhibited reduced phosphatase and tensin homolog expression and a constitu

124 splant patients because of relatively higher phosphatase and tensin homolog expression in the former.

125 y, although AEG-1 knockdown had no impact on phosphatase and tensin homolog expression in these cells

126 Loss of phosphatase and tensin homolog expression was found in 1

127 The miR17-92 cluster mediated PTEN (phosphatase and tensin homolog) expression, which is a p

128 Germline loss-of-function phosphatase and tensin homolog gene (PTEN) mutations cau

129 The phosphatase and tensin homolog gene (PTEN) on chromosome

130 Mutation of the phosphatase and tensin homolog gene in this pool of adul

131 osphorylated Akt and decreased expression of phosphatase and tensin homolog gene, much as is found in

132 lifies the PI 3-kinase signal by maintaining phosphatase and tensin homolog in its inactive phosphory

133 rved downregulation of the tumour-suppressor phosphatase and tensin homolog in schwannoma cells leadi

134 pathway, and its molecular antagonist PTEN (phosphatase and tensin homolog), in the process of gliom

135 dermal growth factor receptor activation and Phosphatase and Tensin homolog inactivation are thought

136 Mutations in the mitochondrial kinase PTEN (phosphatase and tensin homolog)-induced kinase 1 (PINK1)

137 ding to dysfunctional mitochondria via PTEN (phosphatase and tensin homolog)-induced putative kinase

138 lysis and rescue experiments show that PTEN (phosphatase and tensin homolog) is a target of the miR-1

139 ith prostate basal cell-specific deletion of Phosphatase and tensin homolog (K14-CreER;Pten(fl/fl)) d

140 h increased activity of the tumor suppressor phosphatase and tensin homolog, leading to decreased lev

141 unction, impaired NFATc1 activation, reduced phosphatase and tensin homolog levels, and increased Akt

142 miR-21-specific antagomir (Ant-21) increased phosphatase and tensin homolog levels.

143 The importance of PTEN (phosphatase and tensin homolog located on chromosome 10)

144 Increased phosphatase and tensin homolog may thus be responsible f

145 disorder caused by germ-line mutation of the phosphatase and tensin homolog mutated on chromosome 10

146 Inactivation of the tumor suppressor phosphatase and tensin homolog (mutated in multiple adva

147 der have mutations in the lipid phosphatase, phosphatase and tensin homolog on chromosome 10 (Pten).

148 Conversely, PTEN (phosphatase and tensin homolog on chromosome 10) dephosp

149 Cells lacking PTEN (phosphatase and tensin homolog on chromosome 10) functio

150 PTEN (phosphatase and tensin homolog on chromosome 10) is a tu

151 De novo phosphatase and tensin homolog on chromosome ten (PTEN)

152 Phosphatase and tensin homolog on chromosome ten (PTEN)

153 Conditional deletion of Pten (phosphatase and tensin homolog on chromosome ten) in dif

154 eukin-6 or insulin-like growth factor 1, and phosphatase and tensin homolog or RAS alterations.

155 gnaling pathway owing to inappropriately low phosphatase and tensin homolog phosphatase activity.

156 The tumor suppressor PTEN (phosphatase and tensin homolog) plays a critical role in

157 e changes were associated with increased Akt/phosphatase and tensin homolog proliferation/survival si

158 Here, we demonstrate that loss of Pten (phosphatase and tensin homolog) protein at postnatal day

159 Furthermore, RA reduces phosphatase and tensin homolog (Pten) accumulation in mi

160 ansformation-related protein 53 (Trp53), and phosphatase and tensin homolog (Pten) allowed the genera

161 Loss of phosphatase and tensin homolog (PTEN) and activation of

162 nscriptionally in human glioma after loss of phosphatase and tensin homolog (PTEN) and activation of

163 nalysis showed reduced expression of hepatic phosphatase and tensin homolog (PTEN) and CCAAT/enhancer

164 phosphorylation and nuclear translocation of phosphatase and tensin homolog (PTEN) and FOXO 3a.

165 st strongly predicted targets of miR-486 are phosphatase and tensin homolog (PTEN) and Foxo1a, which

166 at PLK3 null MEFs contain a reduced level of phosphatase and tensin homolog (PTEN) and increased Akt1

167 This model was validated using phosphatase and tensin homolog (PTEN) and its ceRNA VAMP

168 Phosphatase and tensin homolog (PTEN) and mothers agains

169 B cells express phosphatase and tensin homolog (PTEN) and multiple isofo

170 However, the phosphatase and tensin homolog (Pten) and neurofibromato

171 through a feedback loop circuit mediated by phosphatase and tensin homolog (PTEN) and PDZ and LIM do

172 acellular signal-regulated kinase (ERK), and phosphatase and tensin homolog (PTEN) and phosphorylatio

173 e 1 in association with the up-regulation of phosphatase and tensin homolog (PTEN) and suppressor of

174 Levels of phosphatase and tensin homolog (PTEN) and suppressor of

175 SCRIB interacts with phosphatase and tensin homolog (PTEN) and the expression

176 ligases Nedd4-1 and Nedd4-2 may ubiquitinate phosphatase and tensin homolog (PTEN) and thereby regula

177 ve demonstrated that tumors deficient of the phosphatase and tensin homolog (PTEN) are often dependen

178 We identified phosphatase and tensin homolog (PTEN) as a novel target

179 ession is associated with phosphorylation of phosphatase and tensin homolog (PTEN) at residues Ser380

180 se (PI3K) pathways cross-talk through a Hes1-phosphatase and tensin homolog (PTEN) axis during normal

181 The phosphatase and tensin homolog (PTEN) can function as a

182 evelopment of invasive adenocarcinoma in the phosphatase and tensin homolog (Pten) conditional deleti

183 ression and mammary tumorigenesis induced by phosphatase and tensin homolog (Pten) deletion in mice.

184 Deletion of the tumour suppressor phosphatase and tensin homolog (PTEN) enhances signallin

185 ts with AD-HIES is associated with increased phosphatase and tensin homolog (PTEN) expression, which

186 multiple tumor cell types, and cells lacking phosphatase and tensin homolog (PTEN) function were rela

187 of PI3K signaling in mice by deletion of the phosphatase and tensin homolog (Pten) gene (which regula

188 Mutations in the human phosphatase and tensin homolog (PTEN) gene cause PTEN ha

189 widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN) generates hamartom

190 er cell growth in which the tumor suppressor phosphatase and tensin homolog (PTEN) has been deactivat

191 A reduction in phosphatase and tensin homolog (PTEN) has been shown to

192 Germline mutations in phosphatase and tensin homolog (PTEN) have been recently

193 mined the expression of the tumor suppressor phosphatase and tensin homolog (PTEN) in 248 primary DLB

194 Deletion of phosphatase and tensin homolog (PTEN) in adult CNS neuro

195 TBX2 directly represses the tumor-suppressor phosphatase and tensin homolog (PTEN) in both RMS and no

196 te the expression levels of tumor suppressor phosphatase and tensin homolog (PTEN) in drug-induced gi

197 previously demonstrated that genetic loss of phosphatase and tensin homolog (PTEN) in mammary fibrobl

198 tudies demonstrated that genetic deletion of phosphatase and tensin homolog (PTEN) in mouse corticosp

199 ll type-specific loss of the PI3K antagonist phosphatase and tensin homolog (PTEN) in myeloid cells r

200 Genetic deletion of the tumor suppressor phosphatase and tensin homolog (Pten) in retinal ganglio

201 sitide-dependent protein kinase 1 (Pdk1) and phosphatase and tensin homolog (Pten) in the male germ l

202 edly impairs tumorigenesis driven by loss of phosphatase and tensin homolog (PTEN) in the mouse prost

203 Conditional genetic deletion of phosphatase and tensin homolog (PTEN) in the sensorimoto

204 Because the lipid phosphatase, phosphatase and tensin homolog (PTEN) inhibits Akt, we g

205 Here, we report that UVB exposure triggers phosphatase and tensin homolog (PTEN) interaction with w

206 Phosphatase and tensin homolog (PTEN) is a critical nega

207 Phosphatase and tensin homolog (PTEN) is a dual phosphat

208 The tumor suppressor phosphatase and tensin homolog (PTEN) is a key inhibitor

209 Phosphatase and tensin homolog (PTEN) is a key modulator

210 Phosphatase and tensin homolog (PTEN) is a major negativ

211 Phosphatase and tensin homolog (PTEN) is a negative regu

212 Phosphatase and tensin homolog (PTEN) is a phosphoinosit

213 Phosphatase and tensin homolog (PTEN) is a tumor suppres

214 We find that the tumor suppressor phosphatase and tensin homolog (PTEN) is an important re

215 ally reduced, even when the tumor suppressor phosphatase and tensin homolog (PTEN) is deleted to enha

216 phosphatase activity of the tumor suppressor phosphatase and tensin homolog (PTEN) is enhanced by the

217 The tumor suppressor phosphatase and tensin homolog (PTEN) is frequently invo

218 The tumor suppressor gene phosphatase and tensin homolog (PTEN) is inactivated in

219 Phosphatase and tensin homolog (PTEN) is one of the mole

220 Phosphatase and tensin homolog (PTEN) is one of the most

221 Here we report that the tumor suppressor phosphatase and tensin homolog (PTEN) is oxidized and in

222 s grown under sphere-forming conditions, and phosphatase and tensin homolog (PTEN) knockdown by shRNA

223 Phosphatase and tensin homolog (PTEN) loss or activating

224 gh module scores of chromosomal instability, phosphatase and tensin homolog (PTEN) loss, and E2F3 tra

225 signaling pathway on liver tumors induced by phosphatase and tensin homolog (Pten) loss.

226 Phosphatase and tensin homolog (PTEN) mediates many of i

227 ignancy, by stabilizing the tumor-suppressor phosphatase and tensin homolog (PTEN) mRNA via a mechani

228 rformed a transposon mutagenesis screen in a phosphatase and tensin homolog (Pten) mutant mice and id

229 Germline phosphatase and tensin homolog (PTEN) mutations cause Co

230 Phosphatase and tensin homolog (PTEN) negatively regulat

231 -1 and MPZ-1 are found in a complex with the phosphatase and tensin homolog (PTEN) ortholog DAF-18, w

232 kdown resulted in a twofold reduction of the phosphatase and TENsin homolog (PTEN) phosphatase expres

233 rexpression of the miR-17-92 cluster reduced phosphatase and tensin homolog (PTEN) proteins and eleva

234 We find here, using the phosphatase and tensin homolog (PTEN) pseudogene as a mo

235 armacologic inhibition of negative regulator phosphatase and tensin homolog (PTEN) resulted in increa

236 nteraction between the 5-HT(2C)R and protein phosphatase and tensin homolog (PTEN) serves as a regula

237 Although the lipid phosphatase phosphatase and tensin homolog (PTEN) suppresses Akt act

238 ctivity arising from a point mutation in the phosphatase and tensin homolog (PTEN) tumor suppressor p

239 the MET growth factor receptor, loss of the phosphatase and tensin homolog (PTEN) tumor suppressor,

240 ltured HCC cells increased expression of the phosphatase and tensin homolog (PTEN) tumor suppressor,

241 oma formation in mice haplodeficient for the phosphatase and tensin homolog (Pten) tumor-suppressor g

242 Moreover, deletion of phosphatase and tensin homolog (Pten) upregulated mTORC2

243 and activator of transcription (STAT3), and phosphatase and tensin homolog (PTEN) was confirmed to b

244 protein tyrosine phosphatase 1B (PTP1B) and phosphatase and tensin homolog (PTEN) were found in hepa

245 ade III disease, and further inactivation of phosphatase and tensin homolog (PTEN) yields GBM.

246 Phosphatase and tensin homolog (PTEN)(shRNA) negatively

247 uting can be further enhanced by deletion of phosphatase and tensin homolog (PTEN), a mechanistic tar

248 log enriched in brain and mTORC1, along with Phosphatase and tensin homolog (Pten), a negative regula

249 Phosphatase and tensin homolog (PTEN), a negative regula

250 Phosphatase and tensin homolog (PTEN), a tumor suppresso

251 ranscriptionally represses the expression of phosphatase and tensin homolog (PTEN), a tumor suppresso

252 Somatic loss of phosphatase and tensin homolog (PTEN), a tumor suppresso

253 by which this occurs is by silencing of the phosphatase and tensin homolog (PTEN), a tumor suppresso

254 endent p38 phosphorylation, higher levels of phosphatase and tensin homolog (PTEN), and diminished Ak

255 mal growth factor receptor (EGFR), EGFRvIII, phosphatase and tensin homolog (PTEN), and methylation s

256 (SPRY2), protein phosphatase 2A (PP2A), and phosphatase and tensin homolog (PTEN), are commonly inac

257 18a to reduce levels of the tumor suppressor phosphatase and tensin homolog (PTEN), both directly and

258 an occur simultaneously with inactivation of phosphatase and tensin homolog (PTEN), but neuroblastoma

259 esence of diarrhea, rash, and EGFRvIII, p53, phosphatase and tensin homolog (PTEN), combination EGFR

260 lanoma, including the tumor-suppressor genes phosphatase and tensin homolog (PTEN), cyclin dependent

261 e carcinogenesis comprising pathways for the phosphatase and tensin homolog (PTEN), fibroblast growth

262 ion and the enzyme that dephosphorylates it, phosphatase and tensin homolog (PTEN), is an important t

263 Three other (phosphatase and tensin homolog (PTEN), myristoylated ala

264 ral compromise of the tumor suppressor gene, phosphatase and tensin homolog (PTEN), occurs in 10% of

265 HES1 transcriptionally silences phosphatase and tensin homolog (PTEN), resulting in AKT

266 ROS elicited oxidation and deactivation of phosphatase and tensin homolog (PTEN), resulting in upre

267 major glioblastoma tumor suppressor protein phosphatase and tensin homolog (PTEN), suggesting that S

268 Several members of the PI3K pathway, phosphatase and tensin homolog (Pten), the forkhead box,

269 3K/Akt signaling by directly down-regulating phosphatase and tensin homolog (PTEN), thereby promoting

270 The phosphoinositide-3-kinase (PI3K), phosphatase and tensin homolog (PTEN), v-akt murine thym

271 s resulted in Zn(2+)-mediated degradation of phosphatase and tensin homolog (PTEN), which impaired in

272 21 and phosphorylated AKT, and downregulates phosphatase and tensin homolog (PTEN), which is involved

273 Phosphatase and tensin homolog (PTEN), which negatively

274 s also known to regulate the activity of the phosphatase and tensin homolog (PTEN), which plays a cri

275 lified in glioblastoma, promotes invasion in phosphatase and tensin homolog (PTEN)-competent and PTEN

276 sue of Blood, Choorapoikayil et al have used phosphatase and tensin homolog (Pten)-deficient zebrafis

277 Previous studies have revealed a phosphatase and tensin homolog (PTEN)-dependent interact

278 Phosphatase and tensin homolog (PTEN)-inactivating mutat

279 interaction partners of MARK2, we identified phosphatase and tensin homolog (PTEN)-induced kinase 1 (

280 ry, data from multiple PD models have linked Phosphatase and tensin homolog (PTEN)-induced putative k

281 Phosphatase and tensin homolog (PTEN)-induced putative k

282 nesin-1 whereas mitochondrial damage induces Phosphatase and Tensin Homolog (PTEN)-induced Putative K

283 t the proliferation of cells lacking CnrN, a phosphatase and tensin homolog (PTEN)-like phosphatase,

284 By crossing our previously established phosphatase and tensin homolog (Pten)-null acute T-lymph

285 aR trafficking and localization, we define a phosphatase and tensin homolog (PTEN)-regulated checkpoi

286 ly activated by loss of the tumor suppressor phosphatase and tensin homolog (PTEN).

287 1 (PBRM1), SET domain containing 2 (SETD2), phosphatase and tensin homolog (PTEN).

288 and miR-106b, microRNAs that repress mRNA of phosphatase and tensin homolog (PTEN).

289 d decreased upon loss of the PI3K antagonist phosphatase and tensin homolog (PTEN).

290 exhibits high protein and activity levels of phosphatase and tensin homolog (PTEN).

291 al simulations and validated by re-analyzing phosphatase and tensin homolog's cross-talk pattern from

292 Low expression of phosphatase and tensin homolog showed a modest associati

293 ion of tumor suppressor genes including p21, phosphatase and tensin homolog, TGFbeta receptor II, and

294 xpress SMAD9(V90M) had reduced expression of phosphatase and tensin homolog; this reduction was also

295 AAD, whereas expression of the miR-21 target phosphatase and tensin homolog was reduced.

296 Cells lacking phosphatase and tensin homolog were as sensitive to the

297 Subsequently, phosphatase and tensin homolog (which suppresses PI3K ac

298 s of FBXW7 and deletion or mutation of PTEN (phosphatase and tensin homolog), which also activates mT

299 epress the PI3K/Akt pathway inhibitor, PTEN (phosphatase and tensin homolog), which in turn facilitat

300 ng pro-B cells lacking the phosphatase Pten (phosphatase and tensin homolog), which negatively regula