ライフサイエンスコーパス: phosphatidylinositol 3,5-bisphosphate

1 C2 is a Na(+)-selective channel activated by phosphatidylinositol 3,5-bisphosphate.

2 s, phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,5-bisphosphate.

3 atidylinositol-5-phosphate (PI(5)P) or d-myo-phosphatidylinositol-3,5-bisphosphate.

4 ylating phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate.

5 PTase11 also hydrolyzes the 5-phosphate from phosphatidylinositol (3,5) bisphosphate.

6 onal marker) and its upstream molecule FIG4 (phosphatidylinositol (3,5)-bisphosphate 5-phosphatase) a

7 4 localized to lysosomes and associated with phosphatidylinositol (3,5)-bisphosphate, a key component

8 altered phosphoinositide levels [increase in phosphatidylinositol (3,5)-bisphosphate and decrease in

9 janins leads to increased cellular levels of phosphatidylinositol (3,5)-bisphosphate and phosphatidyl

10 emonstrate that mVps24p selectively binds to phosphatidylinositol 3,5-bisphosphate and phosphatidylin

11 e data provide the first direct link between phosphatidylinositol 3,5-bisphosphate and the protein ma

12 This phase depends on the production of phosphatidylinositol-3,5-bisphosphate and the Fab1 compl

13 PIKfyve is a lipid kinase that generates phosphatidylinositol-3,5-bisphosphate and, directly or i

14 phatidylinositol 3-phosphate and synthesizes phosphatidylinositol 3,5-bisphosphate, and plays a criti

15 rylating phosphatidylinositol-3-phoshate and phosphatidylinositol-3,5-bisphosphate, and some members

16 It is accelerated by the PI(3)P- and phosphatidylinositol 3,5-bisphosphate-binding protein At

17 osphate in the identification of a mammalian phosphatidylinositol 3,5-bisphosphate-binding protein, m

18 erentially with maturing macropinosomes in a phosphatidylinositol 3,5-bisphosphate-dependent manner a

19 Kfyve modulates phagosome maturation through phosphatidylinositol-3,5-bisphosphate-dependent activati

20 n with synthetic biotinylated derivatives of phosphatidylinositol 3,5-bisphosphate in the identificat

21 Phosphatidylinositol 3,5-bisphosphate is a membrane lipi

22 hat the Vac14 protein, like Vac7p, regulates phosphatidylinositol 3,5-bisphosphate levels and possibl

23 FIG4 is a ubiquitously expressed phosphatidylinositol 3,5-bisphosphate phosphatase that r

24 The PPI phosphatidylinositol (3,5)-bisphosphate (PI(3,5)P2) is e

25 hosphatidylinositol 3-phosphate (PI(3)P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P(2)) regu

26 Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P(2)), an

27 The signaling lipid, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P(2)), lik

28 tor cortactin as a direct binding partner of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) and de

29 Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is the

30 Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2), a rec

31 ity and assembly require the signaling lipid phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2).

32 use defects in levels of the signaling lipid phosphatidylinositol 3,5-bisphosphate [PI(3,5)P(2)] lead

33 Phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2] is a l

34 itive to the levels of the low abundant PIP, phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2], becau

35 signaling lipids phosphatidic acid (PA) and phosphatidylinositol(3,5)bisphosphate [PI(3,5)P2].

36 We show that the signaling lipid phosphatidylinositol-3,5-bisphosphate [PI(3,5)P2] is req

37 VPA compromised the dynamics of phosphatidylinositol 3,5-bisphosphate (PI3,5P2) and grea

38 I), phosphatidylinositol-3-phosphate (PI3P), phosphatidylinositol-3,5-bisphosphate (PI3,5P2), and a r

39 The mammalian phosphatidylinositol (3,5)-bisphosphate (PtdIns(3,5)P(2)

40 se (PIKfyve), a lipid kinase which generates phosphatidylinositol (3,5)-bisphosphate (PtdIns(3,5)P(2)

41 smotic stress induces a dramatic increase in phosphatidylinositol 3,5-bisphosphate (PtdIns 3,5-P(2))

42 rter GLUT4 onto the cell surface require the phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2))

43 The phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2))

44 Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2))

45 Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) he

46 Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is

47 the budding yeast Saccharomyces cerevisiae, phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is

48 Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a

49 Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), m

50 Perturbations in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)-sy

51 Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P(2))

52 Phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P(2))

53 analysis, the TRPML1 structure reveals that phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) bi

54 smotically stressed, they rapidly synthesize phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) by

55 the localization and regulation of mammalian phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2), a

56 -abundance and LEL-enriched signalling lipid phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2), w

57 Recently, two novel phosphoinositides, phosphatidylinositol-3,5-bisphosphate (PtdIns-3,5-P2) an

58 hatidylinositol 3-phosphate [PtdIns(3)P] and phosphatidylinositol 3,5-bisphosphate [PtdIns(3,5)P(2)]

59 Phosphatidylinositol-3,5-bisphosphate [PtdIns(3,5)P(2)]

60 PIKfyve is essential for the synthesis of phosphatidylinositol-3,5-bisphosphate [PtdIns(3,5)P2] an

61 wollen endosomal membranes is abrogated when phosphatidylinositol 3,5-bisphosphate synthesis is block

62 s involved in 5' messenger RNA decapping and phosphatidylinositol 3,5-bisphosphate synthesis were als

63 Tritiated arachidonic acid and phosphatidylinositol 3,5-bisphosphate were used to demon

64 For phosphatidylinositol 3,5-bisphosphate, where the two pho

65 ane association (dependent on interaction of phosphatidylinositol 3,5-bisphosphate with the N-termina