ライフサイエンスコーパス: phosphoester

1 prolactone, a cyclic carbonate, and a cyclic phosphoester.

2 mediated nucleophilic attack by water on the phosphoester.

3 d is not inhibited by Etn, choline, or their phosphoesters.

4 er than those of the six-membered monocyclic phosphoester, 2-ethoxy-1,3,2-dioxaphosphinane 2-oxide.

5 d subsequent deprotection of the cyano ethyl phosphoester afforded the target compounds in 16-21 % ov

6 uctures and mechanistic requirements between phosphoesters and peptides during hydrolysis, the study

7 Phosphoesters and phosphonodiesters were synthesized and

8 ter oxygen, such that diverse aryl and alkyl phosphoesters are turned over with similar catalytic eff

9 be involved in metal-dependent catalysis of phosphoester bond hydrolysis.

10 sphopantetheine swinging arm bound through a phosphoester bond to Ser(354) of the intermediate domain

11 redox-active prosthetic groups attached by a phosphoester bond to threonine residues in subunits NqrB

12 it cleaves a pyrophosphate bond instead of a phosphoester bond, and its substrate contains nucleoside

13 ecule to the phosphorus atom of the scissile phosphoester bond, with the attacking water being simult

14 DNA phosphoester bonds are exceedingly resistant to hydrolys

15 rotein kinases both catalyze the transfer of phosphoester bonds from nucleotides to proteins.

16 nzymatic activity in addition to cleavage of phosphoester bonds in RNA.

17 other biochemically important "high-energy" phosphoester bonds.

18 or a closely related analog to catalyze RNA phosphoester cleavage, producing a rate enhancement of a

19 UTP-gamma-aryl and cycloalkyl phosphoesters displayed only intermediate P2Y(6) recepto

20 Qualitatively, the outcome is determined by phosphoester elongation and siloxane contraction along t

21 LPA analogs including a cyclic phosphoester form and ether-linked forms of LPA activate

22 rithiamine interferes with cellular thiamine phosphoester homeostasis is not entirely clear.

23 ructures provide models for intermediates in phosphoester hydrolysis and suggest specific mechanistic

24 bitors toward the hydrolysis of the peptide, phosphoester hydrolysis by peptidases is thus not expect

25 The mechanisms of phosphoester hydrolysis by these enzymes are beginning t

26 er of a large class of enzymes that catalyze phosphoester hydrolysis using a phosphoaspartate-enzyme

27 ously capable of catalyzing carboxyester and phosphoester hydrolysis.

28 d oximolysis rates for acetylthiocholine and phosphoester hydrolysis.

29 edominantly C2'-endo to C3'-endo when the 3'-phosphoester is replaced by a phosphoramidate group.

30 s B and C are bound to threonine residues by phosphoester linkages.

31 ing of small molecules with the 2',3' cyclic phosphoester linkages.

32 The -2 phosphoester or nucleotide is found to increase the reac

33 ecules in solution populate a wider range of phosphoester ring conformations than in R32 and P3 cryst

34 al modeling of the six-membered 3',5'-cyclic phosphoester ring derived from deoxyribose indicated str

35 The results imply a highly flexible phosphoester ring that may be relevant to the function o

36 Our six-membered cyclic phosphoester ring-opening polymerization strategy is dem

37 se library of hyperbranched unsaturated poly(phosphoester)s that allow efficient scavenging of single

38 Both symmetric and antisymmetric phosphoester stretching modes are highly sensitive to P-

39 ns involving inorganic phosphate and organic phosphoesters such as phospholipids, phosphorylated prot

40 at 821 cm-1is demonstrated as diagnostic of phosphoester torsions alpha and zeta in the gauche+ rang

41 ozyme promotes self-cleavage via an internal phosphoester transfer reaction involving the adjacent 2'

42 e in the active site pocket to carry out the phosphoester transfer reaction.

43 ng the 2'-hydroxyl to initiate the reaction (phosphoester transfer).

44 d in other antineoplastic agents influencing phosphoester transfer.

45 structures that promote cleavage by internal phosphoester transfer.

46 w DSPs accomplish similar reaction rates for phosphoesters, whose reactivity (i.e., pK(a) of the leav

47 Fascinatingly, even challenging phosphoesters with poor leaving groups, which were found