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1 d in glycolysis (muscle-specific enolase and phosphofructokinase).
2 ycolysis was activated through activation of phosphofructokinase.
3 ort chain component; and a muscle isozyme of phosphofructokinase.
4 ng two-photon FCS is also demonstrated using phosphofructokinase.
5 m pH 8 to pH 5.0 is detectable for the enyme phosphofructokinase.
6 nding to V(1) subunits and the C terminus to phosphofructokinase.
7 y steps in primary carbon metabolism such as phosphofructokinase.
8 ck regulation of the parasite hexokinase and phosphofructokinase.
9 ose-6-phosphate dehydrogenase (85%), but not phosphofructokinase.
10 and down-regulation of the glycolytic enzyme phosphofructokinase.
12 reduced glucose utilization and activity of phosphofructokinase 1 (PFK-1), which could be reversed b
13 O-GlcNAcylation was induced at serine 529 of phosphofructokinase 1 (PFK1) in response to hypoxia.
15 on of PFKP in human glioblastoma development.Phosphofructokinase 1 (PFK1) plays a critical role in gl
16 de compelling evidence that human liver-type phosphofructokinase 1 (PFKL), which catalyzes a bottlene
17 mmitment, those for Glut1, hexokinase 2, and phosphofructokinase 1, was found to rapidly decline to n
19 equired for glycolysis through activation of phosphofructokinase-1 (PFK-1), one of the key enzymes th
21 e feedback mediated by the glycolytic enzyme phosphofructokinase-1 (PFK1) enables beta-cells to gener
23 and substrate-dependent filament assembly by phosphofructokinase-1 (PFK1), which is considered the "g
24 al. show that the liver-specific isoform of phosphofructokinase-1 forms filaments in vitro and local
25 ume more glucose, did not maintain prolonged phosphofructokinase-1 protein levels and activity, and d
28 osphatase-active kinase-deficient variant of phosphofructokinase 2/fructosebisphosphatase 2, which pr
31 A damage by repressing the expression of the phosphofructokinase-2 (PFK2) isoform 6-phosphofructo-2-k
32 hout the protein amide exchange increases as phosphofructokinase-2 cold denatures provides experiment
33 ssion of the rate-limiting glycolytic enzyme phosphofructokinase-2 in activated astrocytes, and by se
37 ,6-biphosphatase 3 (PFKFB3), which activates phosphofructokinase, a rate-determining enzyme of glycol
39 lexibility caused by invariantly low or high phosphofructokinase activity caused modest mitochondrial
40 ts demonstrate that fatty acyl-CoA modulates phosphofructokinase activity through both covalent and n
43 dulating circulating substrates and reducing phosphofructokinase activity; however, in the recovered
44 rmine whether FBP and citrate (inhibitors of phosphofructokinase) ameliorate hypoxia-induced injury t
45 n bears closest homology to a subdomain of 6-phosphofructokinase, an important enzyme in the glycolyt
46 ediated by allosteric feedback regulation of phosphofructokinase and ADP-glucose pyrophosphorylase.
49 to obtain flux through 'distal' glycolysis (phosphofructokinase and beyond) to lactate; 'proximal' f
50 crystal structures of the glycolytic enzymes phosphofructokinase and enolase are presented and discus
53 irectly transactivates genes encoding GLUT1, phosphofructokinase, and enolase and increases glucose u
54 y steps of glycolysis, including hexokinase, phosphofructokinase, and pyruvate kinase, appeared to be
55 phosphate (Rib-1,5-P2), potent activators of phosphofructokinase, (b) the enzymes responsible for the
59 raphy on PP1-Sepharose and was identified as phosphofructokinase by partial amino acid sequence analy
60 olase C (AldoC, also known as zebrin II) and phosphofructokinase C and the excitatory amino acid tran
61 of Vmax values for flight muscle hexokinase, phosphofructokinase, citrate synthase, and cytochrome c
62 e, glyceraldehyde-3-phosphate dehydrogenase, phosphofructokinase, deoxyhemoglobin, p72syk protein tyr
63 was found for fructokinase and PPi-dependent phosphofructokinase during cell division and for sucrose
64 uvate (PEP) to the single allosteric site on phosphofructokinase (EC ) from Bacillus stearothermophil
67 ction during growth on inulin, whereas the 1-phosphofructokinase enzyme and linked sugar phosphotrans
68 for glycogen phosphorylase, hexokinase, and phosphofructokinase, enzymes catalyzing nonequilibrium r
71 properties of a tryptophan-shifted mutant of phosphofructokinase from Bacillus stearothermophilus (Bs
72 interactions that exist in the homotetramer phosphofructokinase from Bacillus stearothermophilus is
73 the pattern determined for PEP inhibition in phosphofructokinase from Bacillus stearothermophilus, su
77 n reported to be a nonallosteric analogue of phosphofructokinase from Escherichia coli at pH 8.2.
79 ve study of the LbPFK structure with that of phosphofructokinases from E. coli (EcPFK) and Bacillus s
81 transporter GLUT1, phosphoglucose isomerase, phosphofructokinase, glyceraldehyde-3-phosphate dehydrog
82 tegrin beta2) and PFKL (the liver isoform of phosphofructokinase), has proven refractory to cloning,
84 stematic addition of fructose 6-phosphate to phosphofructokinase in the absence and presence of sever
85 and inhibitors of wild-type Escherichia coli phosphofructokinase influenced the kinetic rate and equi
86 nine residues (Arg-433 and Arg-429) of mouse phosphofructokinase is used to identify the ATP inhibito
87 is system (e.g. hexokinase, pyruvate kinase, phosphofructokinase, isocitrate dehydrogenase and citric
88 ldehyde-3-phosphate dehydrogenase, aldolase, phosphofructokinase, lactate dehydrogenase, and pyruvate
92 on studies have shown that endogenous PFK-M (phosphofructokinase, muscle-specific isoform) associates
93 ak1-interacting target chromatins, including phosphofructokinase-muscle isoform (PFK-M) and nuclear f
96 study the kinetic mechanism of Ascaris suum phosphofructokinase (PFK) at pH 8.0 for the native enzym
97 nhibits glucose oxidation, and inhibition of phosphofructokinase (PFK) by a rise in citrate so that g
99 te enhances the affinity of Escherichia coli phosphofructokinase (PFK) for fructose 6-phosphate (Fru-
100 of inhibitor-bound and uninhibited forms of phosphofructokinase (PFK) from B. stearothermophilus hav
102 e dependence of the allosteric properties of phosphofructokinase (PFK) from Bacillus stearothermophil
110 he key event was proposed to be an increased phosphofructokinase (PFK) Vmax secondary to an upregulat
111 phosphate shunt activity, (c) 50% increased phosphofructokinase (PFK) Vmax, (d) a normal ATP/ADP rat
112 have demonstrated a similar distribution of phosphofructokinase (PFK) with caveolin-1 (CAV-1) mainly
113 ocated previously (such as AMP activation of phosphofructokinase (PFK), ADP inhibition of ATPase and
114 e located 18 bp downstream of the gene for 6-phosphofructokinase (PFK), is a PSTK for M. xanthus PFK
115 d glucose transporter 3 (GLUT-1 and GLUT-3), phosphofructokinase (PFK), lactate dehydrogenase (LDH),
116 xed and stained with Abs to GAPDH, aldolase, phosphofructokinase (PFK), pyruvate kinase (PK), lactate
117 is even more common among cyanobacteria than phosphofructokinase (PFK), the key enzyme of the EMP pat
120 xtracts, we identified the muscle isoform of phosphofructokinase (PFK-M) as a protein that binds to n
122 , glpR was cotranscribed with the downstream phosphofructokinase (PFK; pfkB) gene, and the transcript
123 We also find that the specific activity of phosphofructokinase (PFK; the rate limiting enzyme in gl
125 A yeast strain lacking the beta-subunit of phosphofructokinase (pfk2Delta) accumulates a high level
126 ies of pyruvate kinase (PykF, but not PykA), phosphofructokinase (PfkB, but not PfkA), glucosamine-6-
128 rate-limiting glycolytic enzyme muscle-type phosphofructokinase (PFKm, >2 fold, P<0.05) and accumula
130 ulates expression of the platelet isoform of phosphofructokinase (PFKP), the rate-limiting enzyme of
131 to mitochondrial ATP production in hypoxia: phosphofructokinase, phosphoglucokinase, complex II, com
136 glycogen phosphorylase, hexokinase I, muscle phosphofructokinase, the E1alpha subunit of pyruvate deh
137 a potent inhibitor of the glycolytic enzyme phosphofructokinase, the pacemaker of glycolytic oscilla
138 nase, to form fructose 6-phosphate, and (ii) phosphofructokinase, to form fructose 1,6-bisphosphate,
141 system, whereas a distinct inulin-induced 1-phosphofructokinase was linked to a fructose-specific ph
142 Pathways branching off of glycolysis above phosphofructokinase were activated as indicated by over
143 properties of the wild-type Escherichia coli phosphofructokinase were compared to the E187A mutant by
144 enase, 6-phosphogluconate dehydrogenase, and phosphofructokinase were significantly reduced in Deltah
145 The rate-limiting step was most likely at phosphofructokinase, which has a Km(Mg2+) of 0.025 mM in
146 thanococcus jannaschii is now annotated as a phosphofructokinase, which was regarded previously as a
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