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1 glycerol, PG, another low-abundance class of phospholipids).
2 nd was critical for AA release from membrane phospholipids.
3 ng and anti-inflammatory effects of oxidized phospholipids.
4 E5 to limit polar interactions with membrane phospholipids.
5 otein trafficking, and the cellular roles of phospholipids.
6 membrane microdomains enriched with specific phospholipids.
7 esters, surrounded by a single monolayer of phospholipids.
8 little is known about its activity on diacyl phospholipids.
9 dinating the polar head-groups of transiting phospholipids.
10 e used for the de novo synthesis of membrane phospholipids.
11 major oxidation products of the unsaturated phospholipid 1-palmitoyl-2-arachidonoyl-sn-glycero-phosp
12 lesterol were prepared using three different phospholipids (1,2-dimyristoyl-sn-glycero-3-phosphocholi
16 ophysical methods, here we show that anionic phospholipids activate the cpSRP receptor cpFtsY to prom
18 changes in the acyl chain composition of ER phospholipids affect SREBP-1c maturation in physiology a
20 reveal an unforeseen metabolic function for phospholipid and histone methylation intrinsic to the li
21 id synthesis, membrane protein biosynthesis, phospholipid and membrane protein trafficking, and the c
22 ent with previously reported data on altered phospholipid and receptor binding, we hypothesize that m
23 of hydrogen bonds between the polar zone of phospholipid and the OH groups of phenolic compounds.
24 c interactions between negatively charged PM phospholipids and basic amino acids found in K-Ras4B (K-
25 ospholipon 90H) or unsaturated (Lipoid S100) phospholipids and characterized for size, polydispersity
27 ally driven by dextran depletants instead of phospholipids and cholesterol with prominent electrostat
28 ate from the interdigitation between surface phospholipids and core neutral lipids that occurs in LDs
29 ifungal activity, recruits multiple membrane phospholipids and forms oligomers in their presence.
32 udied the enzymatic modification of egg yolk phospholipids and its effect on physicochemical properti
33 ted bacterial effectors can bind to membrane phospholipids and may regulate membrane trafficking.
34 so addresses other factors, including acidic phospholipids and modification of ENaC cytoplasmic cyste
35 d droplets (LDs) are covered with a layer of phospholipids and oleosin and were extensively studied b
37 B1 from Shigella flexneri may bind to acidic phospholipids and regulate actin filament dynamics.Micro
40 chain-dependent differential localization of phospholipids and triacylglycerols was observed within t
43 ll as insoluble lipid surfactants, including phospholipids, and proteins, a composition similar to pu
45 hat an engineered opsin monomer can scramble phospholipids, and that the lipid-exposed face of TM4 is
48 f GM1-containing NDs prepared with the three phospholipids are found to be similar in magnitude, indi
52 yer perturbation effects of the two oxidized phospholipids based on the chemical identities of their
53 hereby facilitating transbilayer exchange of phospholipids between the leaflets of the vesicle membra
54 reports the distribution coefficient between phospholipid bilayer membranes and phosphate buffered sa
55 itations by reconstituting unlabeled LeuT in phospholipid bilayer nanodiscs, subjecting them to hydro
56 a(2+), reconstituted OmpLA diffused within a phospholipid bilayer without revealing any signs of phos
62 he membrane interactions of the peptide with phospholipid bilayers and its membrane topology using st
63 These results suggest that supported fluid phospholipid bilayers are not homogenous at the nanoscal
64 tack bacterial membranes and upon landing on phospholipid bilayers instantaneously (seconds) convert
65 -length and truncated constructs of CXCR1 in phospholipid bilayers under physiological conditions.
66 holesterol-binding site of the M2 protein in phospholipid bilayers using solid-state NMR spectroscopy
69 f1 requires both its ubiquitin-ligase and C2 phospholipid-binding domains, and involves K48- rather t
70 ive factor attachment protein receptor)- and phospholipid-binding protein that localizes to and prime
72 ersistent presence of autoantibodies against phospholipid-binding proteins (aPLs), such as beta2 glyc
73 important mechanism that couples the rate of phospholipid biosynthesis and endomembrane biogenesis to
74 epressor Opi1p, which controls expression of phospholipid biosynthesis genes, but the mechanisms cond
77 r characterize the ER subdomain, we screened phospholipid biosynthetic enzymes and found that the aut
79 BR scrambles fluorescent analogues of common phospholipids but does not transport a glycosylated diph
82 idine metabolism, fatty acid beta-oxidation, phospholipid catabolism, arachidonic acid and linoleic a
83 species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters in OG-
84 he three-dimensional spatial distribution of phospholipid classes, phosphatidylcholine (PC), phosphat
86 MBs), consisting of an oxygen gas core and a phospholipid coating functionalised with Rose Bengal (RB
89 on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to the exocy
91 RBCs or plasma, but was associated with the phospholipid composition of the RBC membranes and with p
92 cteristic of the OM is lipid asymmetry, with phospholipids comprising the inner leaflet and lipopolys
95 lar levels of citrate, the ratio of ATP/ADP, phospholipid content, and ATP citrate lyase expression.
96 bilayer, but the subsequent realization that phospholipids could also serve as second messengers brou
97 erein for the first time, join other complex phospholipid defects that cause leukoencephalopathies in
99 ion of purified rhodopsin reconstituted into phospholipid/detergent bicelles with rhodopsin reconstit
101 itol-4,5-bisphosphate (PIP2), one of the key phospholipids, directly interacts with several membrane
102 stems we investigated DNA oligomers (3-HPA), phospholipids (dithranol, THAP, HABA), and non-covalent
104 brane solubilization of a negatively charged phospholipid (DPhPG) with the motivation of creating bio
105 wn-regulation of synj1 rescues blast-induced phospholipid dysregulation and prevents development of T
106 s oxidative modification of lipoproteins and phospholipids, endothelial cell activation, and macropha
107 ation, suggests that Al reacts with membrane phospholipids, enhancing intracellular transport of meta
108 retain activity in detergent extracts) that phospholipid environment is a strong determining factor
109 re extracted with food grade ethanol and egg phospholipids (ePL) produced by deoiling with acetone.
111 peutic potential of the clinical-grade alkyl-phospholipid ether analog CLR1404, 18-(p-iodophenyl)octa
113 gical processes, including lipid metabolism, phospholipid exchange, metabolite transport, signaling,
115 -terminal helix; (iii) the energy barrier of phospholipid extraction from the membrane is lowered by
117 enriched (13)C from fullerol into microbial phospholipid fatty acids (PLFA) we also report, for the
118 cted at the seafloor by quantifying sediment phospholipid fatty acids (PLFAs) and their carbon stable
119 kers.We aimed to assess the utility of serum phospholipid fatty acids (PLFAs) as biomarkers of dietar
120 oids, tocopherols, folate, vitamin B-12, and phospholipid fatty acids, were collected at the beginnin
124 in controlling the levels of polyunsaturated phospholipids for the proper functioning of cell membran
127 to mediate retrograde transport of misplaced phospholipids from the outer leaflet of the OM to the cy
128 in baboons infused with factor Xa (FXa) and phospholipids (FXa/phosphatidylcholine-phosphatidylserin
129 MP), an important but low-abundance class of phospholipids, has been hindered due to its difficulties
131 ractions as well as hydrogen bonding between phospholipid head groups and amine groups of chitosan.
133 amine further limited its interactions with phospholipid head-groups to facilitate pseudopilin membr
134 ta suggest that ApoE proteins regulate brain phospholipid homeostasis in response to TBI and that the
135 tochondrial PC synthesis pathway to cellular phospholipid homeostasis, and establish the importance o
136 tical role for ER-localized Psd1 in cellular phospholipid homeostasis, question the significance of a
137 associated with increased oxidative stress, phospholipid hydrolysis and energy depletion that are ch
138 he amino acid cysteine, or by inhibiting the phospholipid hydroperoxidase glutathione peroxidase 4 (G
139 l and an exchangeable mimic of a low-melting phospholipid in liquid-disordered bilayers can be much s
141 maintenance of sufficiently high amounts of phospholipid in the Salipro nanoparticle to mimic a real
142 yceride species and a subsequent decrease in phospholipids in cART/HIV-1-exposed infants compared to
143 re for the high-throughput identification of phospholipids in data acquired by LC-MS and shotgun expe
146 This paper presents a method for determining phospholipids in soybean lecithin samples by phosphorus
147 and lower levels of cardiolipin, among other phospholipids in the apical plasma membrane compared to
149 d virus infections by specifically targeting phospholipids in the lipid bilayer via the production of
152 lipase A2 activity that acts on the membrane phospholipids, including the phosphoinositides, to form
153 oconvertible tag (for lamin B1) and membrane phospholipid incorporation using stable isotope labellin
155 demonstrating polar-lipid, and specifically phospholipid, inhibition of prion-seeded amyloid formati
157 RAL specifically to 11cRAL through a retinyl-phospholipid intermediate in photoreceptor membranes.
158 experiments, LIMP-2 facilitates transport of phospholipids into murine fibroblasts, with a strong sub
159 h anchors when aggregated to sort subsets of phospholipids into nanoclusters with defined lipid compo
161 gh a non-enzymatic process involving retinyl-phospholipids.It is currently thought that visual pigmen
162 dylinositol phosphate kinase (PIPKIgamma), a phospholipid kinase generating PIP2, is positively expre
163 a-3) essential fatty acid (EFA) supplements, phospholipid (krill oil) and triacylglyceride (fish oil)
164 cholesterol, XL-HDL-free cholesterol, XL-HDL phospholipids, L-HDL cholesterol, and L-HDL-free cholest
167 metry further identified specific effects on phospholipids linked to both neural development and neur
168 spholopion-90H and 80H) and non-hydrogenated phospholipids (Lipoid-S100) in combination with choleste
169 fy oxidized lipids (glycerides, fatty acids, phospholipids, lysophospholipids, and galactolipids) and
170 3-benzoxadiazol-4-y l)], incorporated into a phospholipid membrane bilayer supported on 3 mum silica
171 GTPase-driven actin polymerization at model phospholipid membrane bilayers in cell-free extracts and
172 e show results of the membrane dynamics of a phospholipid membrane multilayer-stack on a solid substr
173 r the ceramide moiety nor the surface of the phospholipid membrane plays a significant role in CTB5 b
174 cs simulations of a BR trimer in an explicit phospholipid membrane revealed water penetration along t
175 onstrate the suitability of a size-adaptable phospholipid membrane-mimetic system for solution NMR st
182 decarboxylases (PSDs) are central enzymes in phospholipid metabolism that produce phosphatidylethanol
184 The UPR has long been known to regulate phospholipid metabolism, and Lpl1's relationship with Ha
187 se include altered calcium, cholesterol, and phospholipid metabolism; altered mitochondrial dynamics;
189 sults suggest greater alteration of membrane phospholipid metabolisms in rapid cycling BD-I compared
191 palmitoyl-sn-glycero-3-phosphocholine (DPPC) phospholipid mixtures using quartz crystal microbalance-
192 high sensitivity to the spatial proximity of phospholipid molecules near the sensor surface, the LSPR
193 degraded the membrane with a turnover of 2 phospholipid molecules per second and per OmpLA dimer un
195 e of model membranes represented by Langmuir phospholipid monolayers and Aerosol-OT (AOT) reverse mic
196 n micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positio
197 re, we present a protocol on the assembly of phospholipid nanodiscs of various sizes for structural s
201 idylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Ke
204 re was no difference in the total amounts of phospholipids of each class, we revealed that the levels
205 The influence of two bioactive oxidized phospholipids on model bilayer properties, membrane pack
207 monstrate that exposure of HAECs to oxidized phospholipids or pro-inflammatory cytokines results in s
208 circulation of a specific group of oxidized phospholipids (oxPCCD36) that are ligands for the platel
209 and lipoproteins are converted into oxidized phospholipids (OxPL) by oxidative stress promoting ather
211 e to seek other, non-signaling functions for phospholipids, particularly in their interactions with m
212 may interact positively with EVOO to inhibit phospholipid peroxidation, and thus, McPC-EEVOO could be
213 ockout mice lacking the LPA-degrading enzyme phospholipid phosphate phosphatase type 1 (PLPP1) had a
214 rge lipids up to m/z of 1000, including lyso-phospholipid, phosphatidic acid (PA), phosphoethanolamin
215 haliana stimulates biosynthesis of the major phospholipid phosphatidylcholine (PC) and causes expansi
216 suppress the signals from the most abundant phospholipids (phosphatidylcholine (PC) and phosphatidyl
217 grees with markers for the anionic signaling phospholipids phosphatidylinositol 4,5-bisphosphate and
221 ormal WHAMM function involved binding to the phospholipid PI(3)P and promoting actin nucleation at na
222 otably, both activators require the membrane phospholipid PIP2 but appear to interact independently w
224 r in different lipid compartments, including phospholipids, plasma, cholesterol esters, and adipose t
225 isruptions in membrane structure by oxidized phospholipids play a role in the regulation of overall e
226 d a rapid and progressive change in membrane phospholipid polarity, manifested as phosphatidylserine
227 acted considerable attention because it is a phospholipid precursor, a lipid second messenger, and a
228 d in both positive- and negative-ion mode to phospholipids present in human serum, and the data set w
229 otentially targeting domain organization and phospholipid-protein binding, which has implications for
233 evious findings that all three proteins bind phospholipids, results presented here indicate that mult
234 ins, which form a nucleational core with the phospholipid-rich membrane and support the formation of
236 a protein functioning as a Ca(2+)-dependent phospholipid scramblase and Ca(2+)-activated chloride ch
237 The G protein-coupled receptor opsin is a phospholipid scramblase that facilitates rapid transbila
238 ruption of this asymmetry by ATP-independent phospholipid scrambling is important in cellular signali
240 ysiological implications of Ca(2+)-dependent phospholipid scrambling, the extracellular vesicles asso
242 bolite classes and study groups-for example, phospholipids showed maximal difference at 5:00 AM (lean
243 injured neurons, is dependent on exposure of phospholipid signals, and is achieved through the balanc
244 ne, and we observed that the upregulation of phospholipid species and cholesterol is correlated with
246 Phosphatidylethanolamine (PE) is a major phospholipid species with important roles in membrane tr
250 or hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid
252 ation and active provision of a procoagulant phospholipid surface enriched in 12/15-lipoxygenase-deri
253 analyses showed that LPIN1 knockdown blocks phospholipid synthesis and changes membrane lipid compos
256 P) controlling the rate-limiting step in the phospholipid synthesis pathway, is highly up-regulated i
261 ing the IDO inhibitor, indoximod (IND), to a phospholipid that allows prodrug self-assembly into nano
262 hosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and r
263 ding energy of the LC phase of the saturated phospholipids that are common to all natural and clinica
264 detected regional increases in ether-linked phospholipids that are the precursors of PAF, and global
266 les have been assembled and coassembled from phospholipids, their modified versions, and other single
267 y, whereby it transfers an acyl chain from a phospholipid to the amine group of the N-terminal cystei
268 lipids to the pore, but allows outer leaflet phospholipids to bind to a pronounced ridge surrounding
271 rchitecture prevents access of inner leaflet phospholipids to the pore, but allows outer leaflet phos
273 alpha-helical OM protein that functions as a phospholipid translocation channel, forming a 20-A-thic
276 the likely importance of these hepatobiliary phospholipid transporter genes in the pathology of gallb
277 ifferent approach and mimic the synthesis of phospholipids using abiotic but highly selective bioconj
278 e was studied in the absence and presence of phospholipids using Langmuir films, polarization modulat
280 the gel-to-fluid phase transition in a pure phospholipid vesicle was observed to take place across a
281 chloride-selective permeability to preformed phospholipid vesicles and that this selectivity is stron
283 introduction of linoleic acid, via fusion of phospholipid vesicles to mitochondria isolated from DHA-
284 Kd was not altered either by the presence of phospholipid vesicles, phosphatidylinositol 4,5-bisphosp
285 n which dimerizes en route to insertion into phospholipid vesicles, QUAD opsin reconstitutes as a mon
286 confirmed that ApoL1 stably associates with phospholipid vesicles, requiring low pH and the presence
287 of cytochrome c with cardiolipin-containing phospholipid vesicles, serving as models of the OMM, is
289 poration of very-long-chain fatty acids into phospholipids, we separately examined the effects of lys
291 d per OmpLA dimer until most of the membrane phospholipids were hydrolyzed and the protein became tig
294 laboratory, where both membrane proteins and phospholipids were the foci of study, thus providing a j
295 s, much less is known about the synthesis of phospholipids, which is essential for membrane biogenesi
300 f mutants that disrupt Tau interactions with phospholipids without interfering with its ability to fo
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