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1 ioate, which in turn is more stable than the phosphorodithioate.
2 phosphate, (2) [Rp]-phosphorothioate, or (3) phosphorodithioate.
3 in the mechanism for the S(p) isomer of the phosphorodithioate analogue into a more dissociative typ
4 products of cleavage of phosphorothioate and phosphorodithioate analogues of PI in which sulfur was i
5 trations, an oligomer containing alternating phosphorodithioate and phosphate linkages was able to di
10 ide leading to the quantitative formation of phosphorodithioate diesters uncontaminated with the corr
12 igh-resolution separation of oligonucleotide phosphorodithioates from monothiophosphate impurities wa
13 ion conditions, a hammerhead ribozyme with a phosphorodithioate linkage at the cleavage site cleaved
15 tides containing a site-specific nonbridging phosphorodithioate linkage via automated solid-phase syn
16 onucleotides containing a high percentage of phosphorodithioate linkages in lower salt concentrations
17 mical properties of DNA oligomers containing phosphorodithioate linkages in various configurations we
18 RNase H, DNA oligomers containing up to 50% phosphorodithioate linkages were able to direct RNase H
19 gurations containing phosphoromonothioate or phosphorodithioate linkages were evaluated for antisense
21 eins specifically binding to oligonucleoside phosphorodithioate (ODN) aptamers from a bead-bound ODN
22 hosphorothioate oligonucleotides (S-ODNs) or phosphorodithioate oligonucleotides (S2-ODNs) with sulfu
23 2))T(PO(2))](7)T, which contains alternating phosphorodithioate/phosphate diester internucleotide lin
24 eport a chemical modification, consisting of phosphorodithioate (PS2) and 2'-O-Methyl (2'-OMe) MePS2
27 more than one unmodified linkage separating phosphorodithioates were degraded rapidly by DNase I, wh
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