ライフサイエンスコーパス: phosphorylase

1 nversion to hexose phosphate via a cytosolic phosphorylase.

2 lated metabolites by human purine nucleoside phosphorylase.

3 lymerase and a Mn(2+)*PO(4)-dependent DNA 3'-phosphorylase.

4 einhardtii VTC2 as an active GDP-L-galactose phosphorylase.

5 gene encoding thymidine phosphorylasethymine phosphorylase.

6 was dependent on the DeoD purine nucleoside phosphorylase.

7 as widely inferred to be a purine nucleoside phosphorylase.

8 e in [AMP] is necessary to activate glycogen phosphorylase.

9 igh level in a strain lacking polynucleotide phosphorylase.

10 K), cytidylate kinase, and purine nucleotide phosphorylase.

11 degraded in the cytosol by purine nucleoside phosphorylase.

12 RhlB and the exoribonuclease polynucleotide phosphorylase.

13 hese enzymes act preferentially as glycoside phosphorylases.

14 A second gene, uridine phosphorylase 2, with a joint P-value of 2.3E-9, has bee

15 h vehicle infused ZDF (ZDF-V), high glycogen phosphorylase a activity was decreased and low synthase

16 Thymidine phosphorylase, a cellular enzyme markedly induced by ORF

17 MTAP encodes the enzyme methylthioadenosine phosphorylase, a key enzyme in the methionine salvage pa

18 The plant VTC2 gene encodes GDP-L-galactose phosphorylase, a rate-limiting enzyme in plant vitamin C

19 lly, BMI1 coprecipitated with polynucleotide phosphorylase, a ribonuclease that is responsible for de

20 zyme having both cellodextrin and cellobiose phosphorylases activities.

21 ycemia was associated with elevated glycogen phosphorylase activity and decreased glycogen synthase a

22 atures of these patients including thymidine phosphorylase activity deficiency, elevated thymidine an

23 ain deletions enhance the DNA polymerase and phosphorylase activity of mycobacterial PNPase.

24 VTC2 expression and GDP-L-galactose phosphorylase activity rapidly increase on transfer to h

25 Thymidine phosphorylase activity rose from undetectable to normal

26 vity was approximately 50% greater, glycogen phosphorylase activity was approximately 50% lower, and

27 he purified proteins also display GDP-hexose phosphorylase activity.

28 glycogen synthase and a decrease in glycogen phosphorylase activity.

29 tations cause severe reductions of thymidine phosphorylase activity; marked elevations of the pyrimid

30 rain was found to totally lack GDP-D-glucose phosphorylase activity; this activity was also found to

31 r the treatment of type II diabetes has made phosphorylase an active target of research for the past

32 ue cultured parasites from purine nucleoside phosphorylase and adenosine deaminase blockade but not w

33 l proangiogenic factors, including thymidine phosphorylase and angiopoietin-1 both in vitro and in vi

34 the isoform-specific regulation of glycogen phosphorylase and glycogen metabolism.

35 own-regulation of the expression of glycogen phosphorylase and its activating kinase, phosphorylase k

36 ic enzyme with Mg(2+)*PO(4)-dependent RNA 3'-phosphorylase and Mg(2+)*ADP-dependent RNA polymerase ac

37 Subtracting the S1 domain diminishes RNA phosphorylase and polymerase activity; simultaneous dele

38 chloroplast gene expression (polynucleotide phosphorylase and PTAC12), and prosthetic group attachme

39 nced ribonuclease activity of polynucleotide phosphorylase and reduced mtRNA stability.

40 nucleases of E. coli, such as polynucleotide phosphorylase and RNase II, cannot complement the cold s

41 a coli phosphorolytic RNases, polynucleotide phosphorylase and RNase PH, leads to marked growth and r

42 Thymidine phosphorylase and uridine phosphorylase double knockout

43 nucleotidase cytosolic-II, purine nucleoside phosphorylase and xanthine oxidase) was performed using

44 both human and Plasmodium purine nucleoside phosphorylases and adenosine deaminases are inhibited.

45 annose are conserved in both GH130 mannoside phosphorylases and beta-1,2-mannosidases.

46 s such as in permeabilized cells that harbor phosphorylases and kinases, ion pumps exhibiting substan

47 rylase phosphatase, inactivation of glycogen phosphorylase, and activation of glycogen synthase.

48 ndoglucanase, cellobiohydrolyase, cellobiose phosphorylase, and alpha-glucan phosphorylase originatin

49 e components (RNA helicase B, polynucleotide phosphorylase, and enolase) are organized as helical fil

50 tein phosphatase 1 (PP1), glycogen synthase, phosphorylase, and laforin.

51 ed that uridine hydrolase, purine nucleoside phosphorylase, and methylthioadenosine phosphorylase are

52 o the multiple binding sites of the glycogen phosphorylase, and then we have investigated the use of

53 eported examples of retaining beta-glycoside phosphorylases, and the first instance of free beta-GlcN

54 s, including glycoside hydrolases, glycoside phosphorylases, and transglycosylases.

55 Many crystallographic structures of phosphorylase are currently available to aid in this res

56 oside phosphorylase, and methylthioadenosine phosphorylase are required for Nrk-independent utilizati

57 Nucleoside phosphorylases are essential for the salvage and catabol

58 (HsPNP) and bovine (BtPNP) purine nucleoside phosphorylases are homotrimers with the catalytic sites

59 bonucleotides (synthesized by polynucleotide phosphorylase) as messenger RNA in a cell-free protein-s

60 x that phosphorylates and activates glycogen phosphorylase b (GP b) in a Ca (2+)-dependent reaction t

61 to the analysis of the kinetics of glycogen phosphorylase b (GPb).

62 o enzyme-catalyzed reaction using the enzyme phosphorylase b from rabbit muscle and Deinococcus geoth

63 16 subunits of the (alphabetagammadelta)(4) phosphorylase b kinase (PhK) complex can only be achieve

64 the glycogen branching enzyme (GBE) and the phosphorylase b kinase alpha subunit (PhKalpha) protein,

65 The original report on phosphorylase b' examined the allosteric characteristics

66 It has been reported that phosphorylase b' shows no allostery, neither homotropic

67 of phosphorylase that lacked the N-terminus (phosphorylase b').

68 time the full thermodynamic effect of AMP on phosphorylase b.

69 ing the allosteric effect of AMP on glycogen phosphorylase b.

70 determine whether plasma levels of glycogen phosphorylase BB (GPBB) isoform increased in patients wi

71 ion enzymes glycogen synthase I and glycogen phosphorylase BB, dispersed throughout the type I cell c

72 ldithiocarbamate suggest that brain glycogen phosphorylase (bGP) and glycogen metabolism could be alt

73 reactive cysteine residues in brain glycogen phosphorylase (bGP).

74 In these phosphorylases, bond cleavage was mediated by a single d

75 ere we show that mammalian purine nucleoside phosphorylase but not methylthioadenosine phosphorylase

76 The Ca(2+)-dependent activation of glycogen phosphorylase by PhK couples muscle contraction with gly

77 time course studies demonstrate that uridine phosphorylase can catalyze the hydrolysis of the fluorin

78 Uridine phosphorylase catalyzes the reversible phosphorolysis of

79 ne (THA_1941) encoding a putative cellobiose phosphorylase (CBP) from Thermosipho africanus TCF52B ha

80 ection, it was categorized as a cellodextrin phosphorylase (CDP).

81 sphoribosyltransferase (TrpD) and nucleoside phosphorylase class II enzymes but bind with high affini

82 ne hydrolase and mammalian purine nucleoside phosphorylase cleave nicotinic acid riboside, whereas th

83 s paralogue VTC5 function as GDP-L-galactose phosphorylases converting GDP-L-galactose to L-galactose

84 using the pyrophosphatase-purine nucleoside phosphorylase coupling system with the chromogenic subst

85 Ribonuclease R (RNR1) and polynucleotide phosphorylase (cpPNPase) are the two known 3'-->5' exori

86 l encephalomyopathy and had severe thymidine phosphorylase deficiency in the buffy coat (<10% of norm

87 e to TYMP mutations that result in thymidine phosphorylase deficiency.

88 A mycoplasma-encoded purine nucleoside phosphorylase (designated PNPHyor) has been cloned and c

89 Chemical inhibition of purine nucleoside phosphorylase did not improve deoxyguanosine recycling b

90 res of human and bovine of purine nucleoside phosphorylases differ, despite 87% homologous amino acid

91 Thymidine phosphorylase and uridine phosphorylase double knockout mice recapitulated several

92 he rNDPs to RNA by the enzyme polynucleotide phosphorylase (EC 2.7.7.8) and detection of the RNA by t

93 rmore, our analyses show that two cellobiose phosphorylases encoded by R. albus 8 can function synerg

94 We show that a GDP-L-galactose phosphorylase, encoded by the Arabidopsis thaliana VTC2

95 m cell transplantation can restore thymidine phosphorylase enzyme function in patients with mitochond

96 uction of known inhibitors from the glycogen phosphorylase enzyme, a therapeutic target against type

97 phorolytic cleavage by pyrimidine nucleoside phosphorylase enzymes.

98 Starch synthases and phosphorylases exhibit highest nucleotide diversities, w

99 Based on high thymidine phosphorylase expression in the liver, a 25-year-old sev

100 It also showed increased glycogen phosphorylase flux in L-G6pc(-/-) mice, which is coupled

101 r selective effective inhibitors of glycogen phosphorylase for the treatment of type II diabetes has

102 lin-dependent kinase 5) from Cdk2, thymidine phosphorylase from a bacterial homologue, and dihydrofol

103 e phosphorolysis, using enzymes cellodextrin phosphorylase from Clostridium stercorarium or Clostridi

104 Deletion of the putative nucleoside phosphorylase gene deoD resulted in an inability of H. p

105 a primer complementary to the polynucleotide phosphorylase gene revealed two major extension products

106 ranscriptional repression of GDP-l-galactose phosphorylase (GGP), a major control enzyme in the ascor

107 cations between orthologs of GDP-L-galactose phosphorylase (GGP), dehydroascorbate reductase (DHAR),

108 es, although recently, a family of glycoside phosphorylases, GH130, have also been shown to target be

109 ity in P-HFF versus P and increased glycogen phosphorylase (GP) activity in both P (1.7-fold greater

110 Glycogen phosphorylase (GP), a key enzyme in glycogen metabolism,

111 gainst muscle and liver isoforms of glycogen phosphorylase (GP).

112 GMPMT was compared with glycogen phosphorylase (GP).

113 tivity against glycogen synthase (GS) and/or phosphorylase (GP).

114 isiae, neutral trehalase (Nth1) and glycogen phosphorylase (Gph1), and show that their activities are

115 eoxyribose-1-phosphate by the host thymidine phosphorylase greatly increases the sensitivity of phage

116 e nicotinic acid riboside, whereas the yeast phosphorylase has little activity on nicotinic acid ribo

117 Interest in the kinetics of glycogen phosphorylase has recently been renewed by the hypothesi

118 Recently, one subfamily, the uridine phosphorylases, has been subdivided into two types which

119 Human MTA phosphorylase (hMTAP) has a transition state structure c

120 His(104) --> Arg) in human purine nucleoside phosphorylase (hPNP), there is an enhancement of catalyt

121 omolar inhibitors of human purine nucleoside phosphorylase (hPNP).

122 Human polynucleotide phosphorylase (hPNPase(old-35)) is a type I IFN-inducibl

123 Human polynucleotide phosphorylase (hPNPase(old-35)) is an evolutionary conse

124 Human polynucleotide phosphorylase (hPNPase(old-35)), a type I IFN-inducible

125 Human thymidine phosphorylase (hTP) is responsible for thymidine (dT) ho

126 Human thymidine phosphorylase (hTP) is responsible for thymidine (dT) ho

127 Selective inhibitors of human uridine phosphorylase (hUP) have been proposed as a strategy to

128 ng likely organellar enzymes: polynucleotide phosphorylase, hydrolytic exoribonuclease, poly(A) polym

129 erase; (ii) LipP, a 5'-amino-5'-deoxyuridine phosphorylase; (iii) LipM, a UTP:5-amino-5-deoxy-alpha-D

130 arly, PI3K/AKT pathway was also activated by phosphorylase in LMP1-induced CD44(+/High) cells.

131 te the activity of the enzyme polynucleotide phosphorylase in Streptomyces species.

132 sequence annotated as a putative nucleoside phosphorylase in the Trypanosoma cruzi genome was overex

133 xplains the occurrence of unexpected uridine phosphorylases in some genomes.

134 olism-related gene MTAP (methylthioadenosine phosphorylase) in SSM resulted in reduced cell growth.

135 erglycemia to directly hyperinhibit glycogen phosphorylase, in turn blocking glycogenolysis causing t

136 )) were measured with and without a glycogen phosphorylase inhibitor (GPI) using [2-(3)H]glucose, [3-

137 Forodesine, a purine nucleoside phosphorylase inhibitor, displays in vitro activity in c

138 Uridine phosphorylase is a key enzyme in the pyrimidine salvage

139 Glycogen phosphorylase is a key enzyme in the regulation of glyco

140 de phosphorylase but not methylthioadenosine phosphorylase is responsible for mammalian nicotinamide

141 Glycogen phosphorylase is the key enzyme that breaks down glycoge

142 atural starch metabolism catalyzed by starch phosphorylase, isoamylase is essential to debranch alpha

143 ists of three isoenzymes, including glycogen phosphorylase isoenzyme BB (GPBB).

144 orter (MEX1), the activity of the plastidial phosphorylase isozyme (PHS1) is increased.

145 hat in normally grown plants, the plastidial phosphorylase isozyme participates in transitory starch

146 In the brain, both muscle and brain glycogen phosphorylase isozymes regulate glycogen mobilization.

147 Skeletal muscle phosphorylase kinase (PhK) is a Ca(2+)-dependent enzyme

148 Phosphorylase kinase (PhK) is a hexadecameric (alphabeta

149 Skeletal muscle phosphorylase kinase (PhK) is an (alphabetagammadelta) 4

150 Phosphorylase kinase (PhK), an (alphabetagammadelta)(4)

151 activation loop with a homologous loop from phosphorylase kinase 1 (Ire1(PHK)).

152 Glycogen phosphorylase kinase activates glycogen phosphorylase, t

153 gen phosphorylase and its activating kinase, phosphorylase kinase alpha.

154 minant manner to completely inhibit glycogen phosphorylase kinase enzyme activity and that this inter

155 oxidation during ferroptosis, which involves phosphorylase kinase G2 (PHKG2) regulation of iron avail

156 n in the catalytic subunit of liver glycogen phosphorylase kinase in a patient with Mauriac syndrome

157 's mother possessed the same mutant glycogen phosphorylase kinase subunit, but did not have diabetes

158 sion of GDP-Man pyrophosphorylase, GDP-l-Gal phosphorylase, l-Gal-1-phosphate phosphatase, GDP-Man-3'

159 by mutations in the gene encoding thymidine phosphorylase, leading to reduced enzymatic activity, to

160 ant worms, suggesting that the GDP-D-glucose phosphorylase may function to remove GDP-D-glucose forme

161 21 mimics into LMP1-transformed cells led to phosphorylase-mediated activation of the PI3K/AKT pathwa

162 5'-Methylthioadenosine phosphorylase (MTAP) and 5'-methylthioadenosine nucleosi

163 Methylthioadenosine phosphorylase (MTAP) and the tumor suppressor genes CDKN

164 ity was identified as 5'-methylthioadenosine phosphorylase (MTAP) based on its biochemical properties

165 that loss of the enzyme methylthioadenosine phosphorylase (MTAP) confers a selective dependence on p

166 doMet) salvage enzyme 5'-methylthioadenosine phosphorylase (MTAP) has been implicated as both a cance

167 e polyamine enzyme methylthioadenosine (MTA) phosphorylase (MTAP) in 36% of lines, transcription fact

168 5-Methylthioadenosine phosphorylase (MTAP) is a key enzyme in the methionine s

169 e salvage pathway enzyme methylthioadenosine phosphorylase (MTAP), frequently deleted in cancer, affe

170 pm inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP).

171 lacking expression of 5'-methylthioadenosine phosphorylase (MTAP).

172 ons of the gene encoding methylthioadenosine phosphorylase, MTAP.

173 c MSP functions via sequential action of MTA phosphorylase (MtnP), 5-(methylthio)ribose-1-phosphate i

174 ation of phosphoglycerate mutase 2, glycogen phosphorylase muscle form, pyruvate kinase muscle isozym

175 e form of Rac 1 GTPase binds to the glycogen phosphorylase muscle isoform (PYGM) and modulates its en

176 emically characterized a putative nucleoside phosphorylase (NP) from the pathogenic protozoan Trypano

177 substrate specificity of UhgbMP, a mannoside phosphorylase of the GH130 protein family discovered by

178 ene expression products as the GDP-D-glucose phosphorylases of these organisms.

179 , cellobiose phosphorylase, and alpha-glucan phosphorylase originating from bacterial, fungal, and pl

180 A level by 20-30%, and KO of GDP-L-galactose phosphorylase (OsGGP) by 80%, while KO of myo-inositol o

181 arum purine salvage enzyme purine nucleoside phosphorylase (PfPNP) is a potential drug target.

182 It was mediated by activation of phosphorylase phosphatase, inactivation of glycogen phos

183 sides STARCH SYNTHASE4 (SS4), the PLASTIDIAL PHOSPHORYLASE (PHS1) also seems to be involved, since dp

184 isting of a bacterial type purine nucleoside phosphorylase (PNP) and a purine nucleoside kinase.

185 the 3' to 5' exoribonuclease polynucleotide phosphorylase (PNP) and additional nucleases are all inv

186 Purine nucleoside phosphorylase (PNP) and xanthine oxidase (XOD) were co-i

187 Human purine nucleoside phosphorylase (PNP) belongs to the trimeric class of PNP

188 Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphoroly

189 sampling study with heavy purine nucleoside phosphorylase (PNP) characterized the experimentally obs

190 otein, 70 kDa (ZAP70), and purine nucleoside phosphorylase (PNP) deficiencies had low responses, pati

191 Purine nucleoside phosphorylase (PNP) deficiency is a rare form of autosom

192 n the rNDP pools generated by polynucleotide phosphorylase (PNP) degradation of RNA is responsible fo

193 Human purine nucleoside phosphorylase (PNP) forms a ribocation-like transition s

194 he dual specificity enzyme purine nucleoside phosphorylase (PNP) functions in both purine recycling a

195 bitors of glycosidases and purine nucleoside phosphorylase (PNP) have been synthesized via selective

196 desine is a new and potent purine nucleoside phosphorylase (PNP) inhibitor.

197 Human purine nucleoside phosphorylase (PNP) is a homotrimer binding tightly to t

198 Human purine nucleoside phosphorylase (PNP) is a homotrimer, containing three no

199 Purine nucleoside phosphorylase (PNP) is a target for the development of t

200 Purine nucleoside phosphorylase (PNP) is an important enzyme in purine met

201 Purine nucleoside phosphorylase (PNP) is part of the human purine salvage

202 as potential inhibitors of purine nucleoside phosphorylase (PNP) isolated from peripheral blood monon

203 Polynucleotide phosphorylase (PNP) plays a central role in RNA degradat

204 Inhibition of human purine nucleoside phosphorylase (PNP) stops growth of activated T-cells an

205 ith the prodrug convertase purine nucleoside phosphorylase (PNP) that locally converts the active met

206 Human purine nucleoside phosphorylase (PNP) was crystallized with transition-sta

207 rystal structures of human purine nucleoside phosphorylase (PNP) with bound inosine or transition-sta

208 icine in 1959 for discovering polynucleotide phosphorylase (PNP), the first enzyme found to synthesiz

209 the chemical step of human purine nucleoside phosphorylase (PNP).

210 abolism of inosine by ecto-purine nucleoside phosphorylase (PNP).

211 he catalytic site of human purine nucleoside phosphorylase (PNP).

212 barrier-crossing) in human purine nucleoside phosphorylase (PNP).

213 ditionally, we identified the Polynucleotide Phosphorylase PNPase as a repressor of yeeJ transcriptio

214 cludes RNA helicase B (RhlB), polynucleotide phosphorylase (PNPase) and enolase.

215 Furthermore, both polynucleotide phosphorylase (PNPase) and RNase II are required for the

216 letions of the genes encoding polynucleotide phosphorylase (PNPase) and RNase R had little effect on

217 sembly in mutants lacking the polynucleotide phosphorylase (PNPase) binding domain led to a significa

218 Polynucleotide phosphorylase (PNPase) catalyzes RNA polymerization and

219 ated that the exoribonuclease polynucleotide phosphorylase (PNPase) facilitates survival of Campyloba

220 t Rsr and the exoribonuclease polynucleotide phosphorylase (PNPase) form an RNA degradation machine t

221 We examined the activity of polynucleotide phosphorylase (PNPase) from Streptomyces coelicolor, Str

222 Polynucleotide phosphorylase (PNPase) is a processive exoribonuclease t

223 rn blotting demonstrated that polynucleotide phosphorylase (PNPase) levels increased in the rnc mutan

224 exoribonucleases RNase R and polynucleotide phosphorylase (PNPase) play critical roles in degrading

225 Polynucleotide phosphorylase (PNPase) plays synthetic and degradative r

226 Escherichia coli polynucleotide phosphorylase (PNPase) primarily functions in RNA degrad

227 in which the exoribonuclease polynucleotide phosphorylase (PNPase) removes the Rho-independent trans

228 ppressor of Var1 3) dimer and polynucleotide phosphorylase (PNPase) trimer form a 330-kDa heteropenta

229 ltransferase (Ntr) family and polynucleotide phosphorylase (PNPase) was examined.

230 owed that the exoribonuclease polynucleotide phosphorylase (PNPase) was required for optimal T3SS fun

231 Previously, we localized polynucleotide phosphorylase (PNPASE), a 3' --> 5' exoribonuclease and

232 Polynucleotide phosphorylase (PNPase), a 3'-to-5' phosphorolytic exorib

233 RNase E, the exoribonuclease polynucleotide phosphorylase (PNPase), a DEAD-box RNA helicase and the

234 c-di-GMP target in E. coli is polynucleotide phosphorylase (PNPase), an important enzyme in RNA metab

235 portantly, cells also lacking polynucleotide phosphorylase (PNPase), and dependent for growth on RNas

236 eam products were degraded by polynucleotide phosphorylase (PNPase), and the downstream products were

237 old shock proteins, including polynucleotide phosphorylase (PNPase), during acclimation phase.

238 RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, an

239 The RNA import component, polynucleotide phosphorylase (PNPASE), facilitates transfer of this hyb

240 osphorolytic exoribonuclease, polynucleotide phosphorylase (PNPase), has previously been shown to be

241 es, RNases II, R, and PH, and polynucleotide phosphorylase (PNPase), participate in maturation of the

242 s, of which two, RNase PH and polynucleotide phosphorylase (PNPase), use inorganic phosphate as a nuc

243 exonuclease turnover enzyme, polynucleotide phosphorylase (PNPase), was shown previously to cause a

244 the chloroplast ribonuclease polynucleotide phosphorylase (PNPase), which consumes and generates pho

245 ns in a mutant strain lacking polynucleotide phosphorylase (PNPase), which is considered the major 3'

246 bolism is the exoribonuclease polynucleotide phosphorylase (PNPase), whose reversible activity is gov

247 of free TRAP, is mediated by polynucleotide phosphorylase (PNPase).

248 ase D, RNase BN, RNase II and polynucleotide phosphorylase [PNPase]) to generate the mature CCA termi

249 Purine nucleoside phosphorylases (PNPs) and uridine phosphorylases (UPs) a

250 ments, we found evidence that polynucleotide phosphorylase processivity was inhibited by a GCGGCCGC s

251 roperties due to enzyme inhibition (glycogen phosphorylase, protein tyrosine phosphatase 1B) or by in

252 nd gluconeogenesis, including liver glycogen phosphorylase (PYGL), phosphoenolpyruvate carboxykinase

253 spectrometry the muscle isoform of glycogen phosphorylase (PYGM) as a novel Rac1 effector molecule i

254 ly, mycoplasma-derived pyrimidine nucleoside phosphorylase (PyNP) activity indirectly potentiated dea

255 tion of protein spots identified as glycogen phosphorylase, pyruvate kinase muscle isozyme, isoforms

256 Thymidine phosphorylase replacement has been achieved by allogenei

257 acid transporter (CAT4) and a polynucleotide phosphorylase resistant to inhibition with fosmidomycin.

258 Deletion of glgB or glgP (glycogen phosphorylase) resulted in defective growth and increase

259 ions with the exoribonuclease polynucleotide phosphorylase, Rsr likely functions in an additional pro

260 The GDP-L-galactose phosphorylase step may therefore play an important role

261 -monophosphate as the source of the sugar, a phosphorylase strategy to generate a sugar-1-phosphate,

262 The nucleotide phosphorylase superfamily 1 encompasses a number of diff

263 The findings imply that the nucleoside phosphorylase superfamily 1 evolved through a series of

264 tive sites of glycogen synthase and glycogen phosphorylase support the idea of a common catalytic mec

265 T. brucei methylthioadenosine phosphorylase (TbMTAP) was found to be responsible for t

266 tion state for the Trypanosoma cruzi uridine phosphorylase (TcUP) reaction has an expanded S(N)2 char

267 ctivity was biochemically determined to be a phosphorylase that could reversibly catalyze adenosine +

268 ucted with a proteolytically derived form of phosphorylase that lacked the N-terminus (phosphorylase

269 led that A. fumigatus contains two trehalose phosphorylases that may be responsible for trehalose pro

270 t the helical organization of polynucleotide phosphorylase, the cytoskeletal-like organization of eno

271 ogen phosphorylase kinase activates glycogen phosphorylase, the enzyme that catalyzes the first step

272 sine, which is readily converted by the DeoD phosphorylase to deoxyribose-1-phosphate, the critical i

273 cose levels physiologically inhibit glycogen phosphorylase to diminish glucose release from the liver

274 cogen shunt and by the potential of altering phosphorylase to treat type II diabetes.

275 In this study, we describe the ability of phosphorylases to participate in the breakdown of human

276 Accordingly, we have generated thymidine phosphorylase (TP) and uridine phosphorylase (UP) double

277 1 (TK1), thymidylate synthase, and thymidine phosphorylase (TP) were analyzed by Western blot and imm

278 de functional domains of TPS and trehalose-6-phosphorylase (TPP) in tandem as a fused gene product of

279 lycerate mutase 2, beta enolase and glycogen phosphorylase), transport proteins (fatty acid-binding p

280 Crystals of bovine uridine phosphorylase treated with 2'-deoxyuridine and sulfate s

281 idine and sulfate and dimeric bovine uridine phosphorylase treated with 5-fluoro-2'-deoxyuridine or u

282 ucture of hexameric Escherichia coli uridine phosphorylase treated with 5-fluorouridine and sulfate a

283 Platelets contain abundant thymidine phosphorylase (TYMP), which is highly expressed in disea

284 Here, we now identify thymidine phosphorylase (TYMP; previously known as endothelial cel

285 ifically to one DNA half-site of the uridine phosphorylase (udp) operator.

286 Alpha skeletal actin, glycogen phosphorylase, unnamed protein product (UNP) similar to

287 ted thymidine phosphorylase (TP) and uridine phosphorylase (UP) double knockout (TP(-/-)UP(-/-)) mice

288 ophosphate decarboxylase (OMPDC) and uridine phosphorylase (UP) genes.

289 the pyrimidine salvage pathway, the uridine phosphorylase (UP) salvage activity was knocked out and

290 nucleoside phosphorylases (PNPs) and uridine phosphorylases (UPs) are closely related enzymes involve

291 ecial polypeptide cap in potato alpha-glucan phosphorylase was essential to push a partially hydrolyz

292 The highest expression of GDP-D-glucose phosphorylase was found in the nervous and male reproduc

293 bsence of the exoribonuclease polynucleotide phosphorylase was markedly diminished when the RNase II

294 as a specific GDP-L-galactose/GDP-D-glucose phosphorylase, we conclude that enzymes catalyzing each

295 ll wall invertase, alpha-amylase, and starch phosphorylase) were expressed at higher levels in stem s

296 ssed either MTN or human methylthioadenosine phosphorylase (which metabolizes MTA without producing M

297 At5g55120, encodes a second GDP-L-galactose phosphorylase with similar properties to VTC2.

298 urther show that a complex of polynucleotide phosphorylase with the direct oxygen sensors DosC and Do

299 e evolution of uridine and purine nucleoside phosphorylases with respect to DNA/RNA metabolism and wi

300 neity, and shown to be a homodimeric uridine phosphorylase, with similar specificity for uridine and