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1 lysis even though these agents increased its phosphorylation level.
2 d MHC II ligation increases overall tyrosine phosphorylation level.
3 al regulation between ACR4 and PP2A-3 at the phosphorylation level.
4 terized by pronounced changes in the protein phosphorylation level.
5 ve HCC1954 cells showing a particularly high phosphorylation level.
6 AR activity in the PVN by reducing the NMDAR phosphorylation level.
7 hatase, which concomitantly restores protein phosphorylation levels.
8 r stage of mitosis, without changing overall phosphorylation levels.
9 was used to determine protein expression and phosphorylation levels.
10 blots revealed no differences in AKT or ERK phosphorylation levels.
11 rylation state of the CTD, reducing its Ser2 phosphorylation levels.
12 ABA were found to have significantly altered phosphorylation levels.
13 ed with a global repression of histone H3S10 phosphorylation levels.
14 0M mutation confers increased Y992 and Y1068 phosphorylation levels.
15 d Bcl-X(L) protein levels, as well as in Bad phosphorylation levels.
16 e to generate high levels of stress with low phosphorylation levels.
17 N4-OH, N7, and N7-OH had substantially lower phosphorylation levels.
18 -type virus substantially reduced eIF2 alpha phosphorylation levels.
19 ere positively correlated with p53 serine 15 phosphorylation levels.
20 , BK stimulates a reduction of PMCA tyrosine phosphorylation levels.
21 ges in metal selectivity, ATP dependence, or phosphorylation levels.
22 ons in the Glc7 phosphatase that increase H3 phosphorylation levels.
23 TCR-CD3 clusters, which scaled with overall phosphorylation levels.
24 m Fam20C-knockout (KO) mice and analyzed the phosphorylation levels.
25 contrast, estradiol but not G1 increased Akt phosphorylation levels.
26 ces global RNA polymerase II (Pol II) Ser(2) phosphorylation levels.
27 acetylation resulted in increases of Ser-294 phosphorylation levels.
28 abling large-scale determination of relative phosphorylation levels.
29 ally overexpress CD30v exhibit increased ERK phosphorylation levels, activation of the canonical NFka
30 but it is restored to nearly half of the pre-phosphorylation level after dissociation and reconstitut
31 quickly elevates CREB Ser133 and ATF-1 Ser63 phosphorylation levels, although the CREB Ser133 phospho
32 noted modification of both eIF4E and 4E-BP1 phosphorylation levels among viruses that produce capped
33 carbon source utilization independent of its phosphorylation level and 2) in cell wall biosynthesis a
34 In addition, activation of MOR elevates the phosphorylation level and kinase activity of PKCzeta.
36 n kinase CK2 normalized the GluN2B Ser(1480) phosphorylation level and the contribution of GluN2A to
38 ts in receptor variants that display reduced phosphorylation levels and are more labile as compared w
39 a GSK3 activity-dependent ability to enhance phosphorylation levels and DNA binding of NF-kappaB p65.
40 unoblot analysis to examine phot2 endogenous phosphorylation levels and in vitro phosphorylation assa
41 al intracellular calcium and resting tyrosyl phosphorylation levels and is highlighted by a marked ab
42 mutant flies showed relatively high S936-TRP phosphorylation levels and light-dark phosphorylation dy
43 otein phosphatase I abolished differences in phosphorylation levels and normalized titin-based passiv
44 cetylation levels correlate with Beclin1 S30 phosphorylation levels and poor prognosis in glioblastom
45 levels correlate with PDH S293 inactivating phosphorylation levels and poor prognosis in glioblastom
47 yperresponsive to IL-4 and show higher Stat6 phosphorylation levels and signaling coupled to downstre
48 ed activation of c-Src and elevated tyrosine phosphorylation levels and subsequent formation of podos
50 zation, which has consequences on overall H1 phosphorylation levels and the stability of H1 binding t
51 eatures, correlating with changes in protein phosphorylation levels and the subsequent development of
52 verexpression of IKK2 increased cellular MLC phosphorylation level, and pharmacological inhibition of
53 e-related changes in Abeta oligomers and tau phosphorylation levels are correlated with decreases in
54 d intracellular Gln3-Myc13 localization, the phosphorylation levels are markedly influenced by severa
57 tumor growth, associated with enhanced Tie2 phosphorylation levels, as compared with low levels in c
58 schizophrenia, a significant decrease in the phosphorylation level at serine 897 (S897) of the NMDA r
60 rostate cancer cell lines, unexpectedly high phosphorylation levels at the Tyr-527 inhibitory site ar
61 trate phosphorylation gradient, with highest phosphorylation levels between the two spindle poles, em
62 eins showing changes in either abundance, or phosphorylation levels, between wild-type and pig-1 muta
63 rporated mutant and WT cTnI, and their basal phosphorylation levels by top-down mass spectrometry dem
64 CPC activity, suggesting that high substrate phosphorylation levels can mask persistent CPC-dependent
71 signature analyses, quantification of STAT5 phosphorylation levels, cytokine neutralization experime
72 n of androgens, Her-2/neu mRNA, protein, and phosphorylation levels decreased linearly with increasin
73 Our data indicate that: (i) observable Gln3 phosphorylation levels do not correlate in a consistent
76 lf-life and is co-regulated, with RNAPII CTD phosphorylation levels, during logarithmic growth in yea
77 myofibrils did not depend on the troponin I phosphorylation level (EC50 P/unP = 0.88 +/- 0.17, p = 0
78 nd long-lasting increase in GSK-3alpha Ser21 phosphorylation levels, followed by a delayed increase i
80 on of responding cells, and amplification of phosphorylation levels for at least one phosphoprotein.
81 and rapamycin combination revealed decreased phosphorylation levels for proteins in both upstream and
82 6 conditions, resulting in 18,816 quantified phosphorylation levels from each multiplexed sample.
83 but not gamma-H2AX foci, and suppressed ATM phosphorylation levels >85% throughout the cell cycle.
85 ylated in 100% confluent BAEC and HUVEC, its phosphorylation level in 50% confluent BAECs or HUVEC wa
86 ucer and activator of transcription (STAT)-6 phosphorylation level in murine heart fibroblasts, and t
90 ric SR protein-phosphatase platform balances phosphorylation levels in a "goldilocks" region for the
91 es was elevated by HU but not Akti XII, AKT2 phosphorylation levels in activated neutrophils and plat
92 r results in significantly elevated receptor phosphorylation levels in cells, both in the absence of
93 Pases) play key roles in regulating tyrosine phosphorylation levels in cells, yet the identity of the
94 NF, and tropomyosin receptor kinase B (TrkB) phosphorylation levels in dorsal CA1, while blocking BDN
97 lin partner CCNK did not affect the bulk CTD phosphorylation levels in HCT116 cells, transcriptome se
98 protein levels, p38 MAP kinase isoforms, and phosphorylation levels in human and porcine TM cells.
99 between SENP3 protein levels and STAT3 Y705 phosphorylation levels in human laryngeal carcinoma spec
101 lasting reversal of the increased GluA1 S831 phosphorylation levels in NAcc shell and persistently bl
102 APK signaling as observed by elevated ERK1/2 phosphorylation levels in progressive lesions and the ap
103 AT-2, STAT-3, STAT-4, and STAT-5 protein and phosphorylation levels in purified T cells, global trans
105 owed these four proteins had higher tyrosine phosphorylation levels in response to CRP in platelets f
106 ng components also exhibited higher tyrosine phosphorylation levels in response to exogenous addition
107 ns in vivo revealed that PTHrP elevated Y418 phosphorylation levels in Src family kinases in CD11b(+)
108 rectly that the most recent estimates of the phosphorylation levels in this system are reasonably acc
112 three drugs increased global cellular kinase phosphorylation levels, including the angiogenesis-relev
114 in (Shc) and phosphoinositol 3-kinase (PI3K) phosphorylation levels increase rapidly, but equilibrate
116 in 4 binding to Munc18c decreased as Munc18c phosphorylation levels increased in pervanadate-treated
118 gene expression to infer changes in protein phosphorylation levels induced in cells by various stimu
119 , is multiply phosphorylated in vivo and the phosphorylation level is dependent on ripening stage and
122 ated in vivo at the basal level and that the phosphorylation level is substantially decreased upon st
124 hypertension, and reducing the NMDA receptor phosphorylation level may be effective for treating neur
125 vourable growth conditions, reduction in FDH phosphorylation levels may prohibit turnover allowing th
126 ceptor-coupled kinase is used to control the phosphorylation level of a response regulator, are commo
128 INS 832/13 cells produced a reduction in the phosphorylation level of Akt, and phosphorylation was re
131 ch effects were associated with an increased phosphorylation level of both Src and extracellular sign
132 l of extracellular signal-regulated kinases, phosphorylation level of c-jun N-terminal kinases, and a
133 astrocytes suggests TSC1/2 and mTOR tune the phosphorylation level of catenin delta-1 by controlling
135 ransformed cells, there is a decrease in the phosphorylation level of cofilin, which is indicative of
136 evated CRMP2 expression accompanies a higher phosphorylation level of CRMP2 and its more pronounced a
137 s, we examined TGFBR2 expression (n=252) and phosphorylation level of downstream target SMAD2 (pSMAD2
138 cessfully been used for measuring changes in phosphorylation level of drug targets and downstream sub
139 along the signaling cascade and parsing the phosphorylation level of each node as a function of its
144 uced upregulation of nitric oxide synthesis, phosphorylation level of extracellular signal-regulated
146 he increased expression of Wnt4 elevated the phosphorylation level of its downstream protein GSK-3 th
150 ux pump, increases due to a reduction in the phosphorylation level of MgrA, which in turn leads to a
159 the TULA-2 gene significantly increased the phosphorylation level of Syk at Tyr-323 and Tyr-352 site
160 n cultured endothelial cells showed that the phosphorylation level of syndecan-4 was significantly re
161 l thereby shows inverse correlation with the phosphorylation level of TAK1 and subsequent reduction i
162 ng ethanol sensitivity, and suggest that the phosphorylation level of the downstream effector ERK is
163 LHCII complexes, coinciding with an elevated phosphorylation level of the LHCII under normal growth l
164 nal sensor both at amplifying changes in the phosphorylation level of the regulator caused by signals
166 pression of titin M-band binding proteins or phosphorylation level of the thin-filament regulatory pr
168 ll spreading, interaction with c-Src, or the phosphorylation level of Tyr-402, Tyr-579/580, and Tyr-8
169 ibody Array analysis, measuring the relative phosphorylation levels of 39 intracellular proteins in u
170 decreased PTEN expression and increased the phosphorylation levels of Akt and downstream targets Fox
171 ere we show that perifosine strongly reduces phosphorylation levels of Akt and extracellular signal-r
173 s FLNA, whereas in the absence of FLNA, high phosphorylation levels of Akt were maintained, enabling
177 milarly, we observe a 30-70% decrease in the phosphorylation levels of all PKA and PKC phospho-sites
178 ed Akt phosphorylation but does not decrease phosphorylation levels of AMP kinase alpha (AMPKalpha).
181 of RBC CR1 causes a significant increase in phosphorylation levels of beta-spectrin that is inhibite
182 ecules (p38, JNK, and ERK) demonstrated that phosphorylation levels of both p38 and JNK were diminish
184 mad7 within the NCC significantly suppressed phosphorylation levels of both Smad1/5/8 and Smad2/3 in
186 kably reduced Ca(2+) leakage and lower basal phosphorylation levels of Ca(2+)-cycling proteins includ
187 ated arginine methylation of SRSF5 and lower phosphorylation levels of cobound SRSF2 enhance shuttlin
188 hosphorylation and contraction to changes in phosphorylation levels of CPI-17 at Thr38, RhoA at Ser18
190 onsiveness to TCR stimulation as assessed by phosphorylation levels of downstream signaling molecules
191 imer mouse model effected an increase in the phosphorylation levels of downstream STEP substrates and
196 in synaptic efficacy correlates with reduced phosphorylation levels of eukaryotic elongation factor 2
198 a RhoA-Rock-PTEN pathway that decreases the phosphorylation levels of GABAAR, thus affecting recepto
199 omotor responding to NAcc AMPA and increased phosphorylation levels of GluR1 (Ser831), a CaMKII site,
203 ion-Western blotting experiments showed that phosphorylation levels of IL-4Ralpha, Janus kinase 1, in
204 reated with CB2 agonists exhibited increased phosphorylation levels of inhibitory sites of the actin-
206 ith concomitant augmentation of the tyrosine phosphorylation levels of insulin-signaling molecules.
208 there was a marked elevation in GSK3beta and phosphorylation levels of its cognate phosphorylation si
209 at a single-cell resolution and studied the phosphorylation levels of key proximal human TCR activat
210 s of the TCR signaling pathway, the tyrosine phosphorylation levels of LAT and SLP-76 are the most af
211 mediate various cellular events and modulate phosphorylation levels of many downstream factors in the
212 ession of SND1-BRAF in H1299 cells increased phosphorylation levels of MEK/ERK, cell proliferation, a
213 at rhMIF induces time-dependent increases in phosphorylation levels of MEK1/2, Erk1/2, and Elk-1, as
214 arge B-cell lymphoma patients had high basal phosphorylation levels of most measured signaling nodes,
215 verexpression of Lyp caused reduction in the phosphorylation levels of multiple proteins in KCL22 chr
218 cin complex 1 (mTORC1) inhibition, since the phosphorylation levels of p70S6 kinase and 4E-BP1 were d
221 ith wild-type H. ducreyi had greatly reduced phosphorylation levels of proteins in the 50-to-60-kDa r
223 uR1, but not PKC, reduced the basal tyrosine phosphorylation levels of Pyk2 and Src, suggesting that
224 183A, and R1S183/201A, demonstrated that the phosphorylation levels of R1S4/201A were significantly l
226 exhibited markedly decreased S(8)/T(1)(7)(0) phosphorylation levels of RIG-I and resistance to infect
227 er analog in vitro, had little effect on the phosphorylation levels of ROCK substrates, migration, in
228 Here we show that TICs exhibit increased phosphorylation levels of S727STAT3 because of PP2A inac
229 noted a 10-40% and a 25-35% reduction in the phosphorylation levels of select sites in old wild type
231 ctivated by protein kinase A even though the phosphorylation levels of Ser2844 are similar to control
232 pe I interferon (IFN)-induced expression and phosphorylation levels of signal transducer and activato
234 ibition is associated with modulation in the phosphorylation levels of signal transducers and activat
236 bserved a 5-10% and a 20-25% increase in the phosphorylation levels of specific sites in young fatigu
237 red livers of rats exhibited increased basal phosphorylation levels of Src, Shc, and ERK, as well as
238 ed IFN-dependent signaling by decreasing the phosphorylation levels of STAT1 while having little effe
240 levels of phosphorylation of JAKs and STAT3, phosphorylation levels of the Akt and mitogen-activated
241 human cancer cells, but had no effect on the phosphorylation levels of the AKT, MEK, and S6 kinase at
242 n, but did not alter the cellular protein or phosphorylation levels of the focal adhesion proteins.
243 ations, 30 was able to increase tyrosine the phosphorylation levels of the IR in the absence of insul
249 s in inhibition of the kinase activities and phosphorylation levels of the three members of the Akt f
250 s were associated with restoration of normal phosphorylation levels of the transcription factor CREB
252 observed dynamic, in vivo alterations in the phosphorylation levels of three key proteins (Akt, FOXO1
253 pocket residues significantly decreased the phosphorylation levels of three p38alpha substrates (ATF
254 h isoproterenol, only the alterations in the phosphorylation levels of troponin I and NADH-ubiquinone
258 nge, we find prolonged elevation in tyrosine phosphorylation levels of VE-cadherin-associated beta-ca
262 rhodopsin species to elucidate the impact of phosphorylation level on arrestin interaction with three
263 p proteins in Bacillus subtilis regulate the phosphorylation level or the DNA-binding activity of res
264 localizes with Cdc5p exclusively when Sec4p phosphorylation levels peak during the cell cycle, indic
265 neither Cps2B phosphatase activity nor Cps2D phosphorylation levels per se are determinants of capsul
266 endent on EGFR activation, as STAT3 tyrosine phosphorylation levels persisted after treatment with AG
267 ignal-regulated kinases1/2 in vitro, and its phosphorylation levels positively correlate with Twist1
270 al isoenzyme thymidine kinase-2, the highest phosphorylation levels relative to thymidine were seen w
273 treatment, TRAIL induces a reduction in MADD phosphorylation levels resulting in MADD dissociation fr
274 of the prpC allele, gliding frequencies and phosphorylation levels returned to the wild-type standar
276 an active conformational state in which its phosphorylation level tends to rise and an inactive one
277 gh all forms induced similar VEGF receptor 2 phosphorylation levels, the angiogenic outcomes were dis
279 P, and vasodilator-stimulated phosphoprotein phosphorylation levels to measure P2Y12 receptor inhibit
280 s was not associated with an increase in AKT phosphorylation levels, underlining the existence of an
281 ysates were analyzed for p38/ERK protein and phosphorylation levels using specific Abs and Western bl
283 oughout the day, while in the C3 species the phosphorylation level was maintained during the entire 2
284 ase, tLIN, was increased when the troponin I phosphorylation level was reduced from 1.02 to 0.3 molPi
286 o wild-type levels, although Btk protein and phosphorylation levels were comparable to controls.
288 otal tyrosine FAK phosphorylation and Tyr397 phosphorylation levels were continuously elevated in PRL
290 hough total JPH2 levels were unaltered, JPH2 phosphorylation levels were found to be reduced in MCM-S
291 K-3beta) association and beta-catenin serine phosphorylation levels were increased and beta-catenin e
296 ascular endothelial growth factor receptor-2 phosphorylation levels were observed in Ang1-expressing
298 a and ischemia-associated changes in protein phosphorylation levels, which can misguide the examinati
299 that CCh stimulates an increase in tyrosine phosphorylation levels, which has been reported to inhib
300 or Dullard knockdown leads to increased Mad phosphorylation levels, while Dullard overexpression res
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