ライフサイエンスコーパス: phosphotyrosine phosphatase

1 relieving an inhibition imposed by a 100-kDa phosphotyrosine phosphatase.

2 ncrease pp68 phosphorylation by inhibiting a phosphotyrosine phosphatase.

3 nuclear DNA, rather than by inhibition of a phosphotyrosine phosphatase.

4 logical role in the activation of a membrane phosphotyrosine phosphatase.

5 d with sodium orthovanadate, an inhibitor of phosphotyrosine phosphatases.

6 alyzed phosphorylation is counterbalanced by phosphotyrosine phosphatases.

7 activity and suggested the involvement of a phosphotyrosine phosphatase 1b (PTP1b) in this process.

8 VEGFR2 by calpain via its substrate protein phosphotyrosine phosphatase 1B (PTP1B), and the relevanc

9 on of suppressor of cytokine signaling-3 and phosphotyrosine phosphatase 1B, two negative regulators

10 Src homology containing phosphotyrosine phosphatase 2 (SHP2) is a positive effec

11 3-kinase (PI3K) or SRC homology 2-containing phosphotyrosine phosphatase 2 (SHP2).

12 9, 81, and 84 in Acr2p resulted in a gain of phosphotyrosine phosphatase activity and a loss of arsen

13 tion of substrate specificity, with enhanced phosphotyrosine phosphatase activity and decreased phosp

14 43-mediated apoptosis, whereas inhibition of phosphotyrosine phosphatase activity by bis(maltolato)ox

15 w that CD5 is constitutively associated with phosphotyrosine phosphatase activity in Jurkat T cells.

16 rmore, peroxovanadate, a potent inhibitor of phosphotyrosine phosphatase activity, inhibited ICl acti

17 ects are presumably due to the inhibition of phosphotyrosine phosphatase activity.

18 FSH promotes the phosphorylation of this phosphotyrosine phosphatase and its dissociation from ER

19 Interactions between SHP-2 phosphotyrosine phosphatase and JAK tyrosine kinases hav

20 taurosporine, inhibitors of tyrosine kinase, phosphotyrosine phosphatase, and protein kinase C, respe

21 phosphotyrosine signaling-tyrosine kinases, phosphotyrosine phosphatases, and Src Homology 2 (SH2) d

22 Shp-2, a src homology (SH)2-containing phosphotyrosine phosphatase, appears to be involved in c

23 smooth muscle cells in which Gi and protein-phosphotyrosine phosphatase are involved, resulting in t

24 ssays, which are done under conditions where phosphotyrosine phosphatases are inhibited and receptor

25 Expression of the phosphotyrosine phosphatase CD45 is essential for B cell

26 The SH2 domain-containing phosphotyrosine phosphatase Corkscrew (CSW) is an essent

27 Sodium vanadate, an inhibitor of phosphotyrosine phosphatases, did not reverse the defici

28 g portions of the amino N-SH2 domain and the phosphotyrosine phosphatase domains, which are involved

29 ich is stimulated by Ephrin A1 (EfnA1) or by phosphotyrosine phosphatase inhibition.

30 Treatment with the phosphotyrosine phosphatase inhibitor bis(maltolato)oxov

31 fect of methoxamine was also mimicked by the phosphotyrosine phosphatase inhibitor pervanadate (PVN).

32 Treatment of adipocytes with the phosphotyrosine phosphatase inhibitor phenylarsine oxide

33 The specific phosphotyrosine phosphatase inhibitor, bpV(phen), dimini

34 Inclusion of bpV(phen), a potent phosphotyrosine phosphatase inhibitor, in the recording

35 A second phosphotyrosine phosphatase inhibitor, phenylarsine oxid

36 lication of pervanadate, an extremely potent phosphotyrosine phosphatase inhibitor, provokes the rapi

37 Conversely, the phosphotyrosine phosphatase inhibitor, sodium vanadate,

38 Moreover, treatment with the phosphotyrosine-phosphatase inhibitor potassium bisperox

39 Jurkat T cells activated by the phosphotyrosine phosphatase inhibitors H2O2 or vanadate

40 oietic cytokine, and CD45RA, an isoform of a phosphotyrosine phosphatase involved in negative regulat

41 homology 2 domain tyrosine phosphatase 1), a phosphotyrosine phosphatase, is considered an important

42 eviously identified for binding by the SHP-2 phosphotyrosine phosphatase.JAK2 tyrosine kinase complex

43 and the recruitment of low-molecular-weight phosphotyrosine phosphatase (LMW-PTP) to receptor comple

44 d EGF binding affinity, or the presence of a phosphotyrosine phosphatase or ATPase.

45 SH2 protein tyrosine phosphatase 2 (SHPTP2) phosphotyrosine phosphatase plays a key role in preventi

46 In contrast, inhibiting the phosphotyrosine phosphatase protein tyrosine phosphatase

47 t LMWCr isolated from bovine liver activates phosphotyrosine phosphatase (PTP) activity in adipocyte

48 idative stress in the mechanism of action of phosphotyrosine phosphatase (PTP) inhibitors was studied

49 Direct measurement of phosphotyrosine phosphatase (PTPase) activity in SUM-52P

50 The low molecular weight phosphotyrosine phosphatases (PTPases) constitute a dist

51 Phosphotyrosine phosphatases (PTPases) regulate cellular

52 cal probes for second-site screening against phosphotyrosine phosphatases (PTPs) using NMR-based tech

53 conserved catalytic site sequence of protein phosphotyrosine phosphatases (PTPs), VXVHCXXGXXR, at ami

54 uramin, a heparin analogue, or inhibitors of phosphotyrosine phosphatases (PTPs; vanadate or calpepti

55 These results suggest that SFKs and putative phosphotyrosine phosphatases regulate the activity of AC

56 logy 2 (SH2) domain containing hematopoietic phosphotyrosine phosphatase SHP-1 in both Jurkat cells a

57 mechanism, in addition to recruitment of the phosphotyrosine phosphatase SHP-1, by which secreted imm

58 g in hematopoietic cells is regulated by the phosphotyrosine phosphatase SHP-1, which is not implied

59 ), phosphatidylinositol 3-kinase (PI3K), the phosphotyrosine phosphatase SHP-2, Grb2, and Src.

60 ymes including Src family members (Src), the phosphotyrosine phosphatase SHP-2, phosphatidylinositol

61 ositol phosphatase (SHIP) and SH2-containing phosphotyrosine phosphatase (SHP)-1, as well as SHP-2 as

62 nd inactivation of Src homology 2-containing phosphotyrosine phosphatase (SHP-2).

63 Phosphotyrosine phosphatase Shp2 has been shown to depho

64 The Src homology 2 domain-containing phosphotyrosine phosphatase (SHP2) is a critical mediato

65 The Src homology 2-containing phosphotyrosine phosphatase (SHP2) is primarily a positi

66 pha1 and the Src homology-2 (SH2)-containing phosphotyrosine phosphatase, SHP2.

67 C gamma, Ras GTPase-activating protein, and phosphotyrosine phosphatase SHPTP2.

68 itors suggests the involvement of a membrane phosphotyrosine phosphatase similar to PTP1A' or PTP1B.

69 restrained at the level of ERK by a 100-kDa phosphotyrosine phosphatase that associates with ERK in

70 also shown to activate by 3-4-fold SHP-1, a phosphotyrosine phosphatase that contains two src homolo

71 effector molecules including SHP-1, a potent phosphotyrosine phosphatase that down-regulates B cell a

72 (PTPases) constitute a distinctive class of phosphotyrosine phosphatases that is widely distributed

73 d by either phosphoprotein phosphatase 2A or phosphotyrosine phosphatase type 1.

74 ing mechanism was ROS-mediated inhibition of phosphotyrosine phosphatases, which antagonize receptor

75 ibing an activation-induced association of a phosphotyrosine phosphatase with tyrosine-phosphorylated

76 Shp-1 and Shp-2 are cytoplasmic phosphotyrosine phosphatases with similar structures.