ライフサイエンスコーパス: photoactivation

1 tudy molecules exhibiting photobleaching and photoactivation.

2 A domain from an inhibited conformation upon photoactivation.

3 uronal GABAA receptors following ultraviolet photoactivation.

4 proteins enables directed HNE delivery upon photoactivation.

5 romyography with hypercapnia and optogenetic photoactivation.

6 ve conjugates against cancer cell lines upon photoactivation.

7 lical content did not change measurably upon photoactivation.

8 fluorescence emission spectra that accompany photoactivation.

9 ha factor into the ligand-binding site after photoactivation.

10 tosystem II (PSII) reaction center is termed photoactivation.

11 tion of a ternary complex that is primed for photoactivation.

12 was hypothesized to be associated with CRY2 photoactivation.

13 n half of c-myb mRNA was degraded 24 h after photoactivation.

14 ection of undissociated precursor ions after photoactivation.

15 in how the LOV1 and LOV2 domains respond to photoactivation.

16 that the cellular response is enhanced with photoactivation.

17 he apo-WOC-PSII protein, a reaction known as photoactivation.

18 ion center is a light-driven process, termed photoactivation.

19 tored using digital imaging microscopy after photoactivation.

20 ulatory domain that senses light and induces photoactivation.

21 diffusion of PpSB1-LOV is not influenced by photoactivation.

22 or the monochromatic UV light enabling rapid photoactivation.

23 tein binding sites utilizing benign, near-UV photoactivation.

24 en these neurons and T4 cells using neuronal photoactivation.

25 ns with other membrane proteins upon in-cell photoactivation.

26 to phycobilisomes, but is not essential for photoactivation.

27 formational rearrangements that occur during photoactivation.

28 nd global structural changes in the OCP upon photoactivation.

29 sed to measure methacrylate conversion after photoactivation (700 mW/cm(2) x 60s) and after 72 h.

30 Upon UVA photoactivation, 8-methoxypsoralen alkylates both strand

31 Upon photoactivation, a fraction of Rh1 is internalized and d

32 Labeled worms showed very bright signal upon photoactivation after hatching, which allowed us to exam

33 monitoring activity; Channelrhodopsin-2 for photoactivation; allatostatin receptor for inactivation

34 the same isoforms of recoverin and GRK1, and photoactivation also triggers a calcium decline in cones

35 ered to colitic WT mice immediately prior to photoactivation, also afforded protection against thromb

36 Finally, photobleaching and photoactivation analysis reveals that the TRIM5 alpha pr

37 Photoactivation and biochemical approaches show that lys

38 pigment epithelial lipofuscin, subsequent to photoactivation and cleavage, serve to activate compleme

39 tosystem II (PSII) reaction center is termed photoactivation and culminates in the formation of the o

40 g poly(ethylene glycol), followed by surface photoactivation and enzyme immobilization in the presenc

41 sed on the role of the OCP N-terminal arm in photoactivation and excitation energy dissipation.

42 We used photoactivation and fluorescence recovery after photoble

43 ropriate spectral properties with respect to photoactivation and formation of the active form, metarh

44 Here, we used T-cell receptor (TCR) photoactivation and imaging methodology to demonstrate t

45 the nucleus, we have demonstrated that both photoactivation and nuclear localization of UVR8 are req

46 m illumination and was verified by quantized photoactivation and photobleaching.

47 ve compared the use of DRONPA and Dendra2 in photoactivation and photoconversion experiments.

48 t side-chain dynamics play a crucial role in photoactivation and signaling of PpSB1-LOV via modulatio

49 Photoactivation and thermal decay of rhodopsin proceed s

50 The photoactivation and visualization are nearly simultaneou

51 large Stokes shifts, (ii) photoconversions, photoactivation, and photoswitching, (iii) phototoxicity

52 enerated using laser-coupled rose Bengal dye photoactivation, and the infarct localized using tetrazo

53 te strand cleavage at the mismatch site with photoactivation, and we observe that the cellular respon

54 , we used a refined fluorescence decay after photoactivation approach and single-molecule tracking.

55 tions that will facilitate extension of this photoactivation approach to other proteins.

56 However, photoactivation approximately 1 min after the induction

57 e fluorescent probes were obtained with fast photoactivation ( approximately 1 min) and high fluoresc

58 singly, two effects of locus coeruleus TH(+) photoactivation are sensitive to hippocampal D1/D5 recep

59 tures reveal that the changes that accompany photoactivation are smaller than previously predicted fo

60 n transfer rates change during the course of photoactivation as the high potential form of Q(A)(-) is

61 the extent of small molecules released after photoactivation as well as pinpoint the location at whic

62 Under photoactivation at 365 nm, they are even more powerful a

63 This avoids photoactivation at low irradiance.

64 gnal transmission mechanisms involved in its photoactivation brought about through a cis-trans photoi

65 dehydrocoupling catalyst and not to require photoactivation, but otherwise operated via a two-step m

66 ing complete domain dissociation, occur upon photoactivation, but with alteration of secondary struct

67 of the PRG can also be brought about without photoactivation, by raising the pH of the enzyme (pKa of

68 namic remodeling of adherens junctions using photoactivation, calcium switch, and coimmunoprecipitati

69 The fact that green-light triggered photoactivation can be efficiently performed both with t

70 s induced by iridium photosensitizers during photoactivation can increase the levels of enzymes invol

71 The photoactivation capability of our CRISPR-plus method is

72 model that describes the first steps of the photoactivation cascade in spatiotemporal detail and sin

73 -D108A, the SB becomes protonated during the photoactivation cascade.

74 ted rats breathing room air, bilateral ArchT photoactivation caused a very small BP reduction that wa

75 Photoactivation causes oxidative damage to specific hist

76 d, D1-D170E lowers the quantum efficiency of photoactivation compared to the wild-type by the largest

77 pH stability, faster photoactivation, higher photoactivation contrast and better photostability.

78 In vivo, CL photoactivation could be shown by using the tumor-specif

79 bers lack GABA, the aversion evoked by their photoactivation depended on glutamate- and GABA-receptor

80 em with a new imaging approach called PhADE (PhotoActivation, Diffusion and Excitation).

81 to identify movements of other helices upon photoactivation, double electron-electron resonance (DEE

82 Using concurrent IR photoactivation during electron transfer dissociation (E

83 of its modular design and tunability of the photoactivation efficiency and photophysical properties,

84 o DNA without sequence specificity and, upon photoactivation, either promotes strand breaks directly

85 ng nanoparticles are described that, upon UV photoactivation, enable controlled acidification of impa

86 tome in vivo analysis (TIVA) tag, which upon photoactivation enables mRNA capture from single cells i

87 a quantitative relation between a pigment's photoactivation energy and its peak-absorption wavelengt

88 l, which is much larger than the 60-kcal/mol photoactivation energy at 500 nm.

89 Photoactivation evoked a rapid depolarization, increased

90 Fluorescence photobleaching and photoactivation experiments also revealed that 1) althou

91 Photoactivation experiments demonstrated that diffusion

92 Photoactivation experiments indicate that microvillar ac

93 ry low quantum yield of the overall process, photoactivation experiments, involving different flash p

94 ilitates single agent-mediated deeper tissue photoactivation, extended imaging and theranostic multim

95 Fluorescence decay after photoactivation (FDAP) and fluorescence recovery after p

96 tial measurements of fluorescent decay after photoactivation (FDAP) of Dronpa-labeled actin.

97 Using a novel in vitro photoactivation fluorescence assay, the EBP50-ezrin inte

98 itution reduced the excitation light-induced photoactivation from the dark to fluorescent state.

99 ster maturation, better pH stability, faster photoactivation, higher photoactivation contrast and bet

100 ferred tag for two-color diffraction-limited photoactivation imaging and for super-resolution techniq

101 s used to examine the molecular mechanism of photoactivation in ASR.

102 The low quantum efficiency of photoactivation in D1-D170E is due to the destabilizatio

103 Photoactivation in PRSX8-ArchT rats reduced breathing fr

104 w that individual cells encode the timing of photoactivation in relation to the sniff in both the tim

105 site-specific anxiolytic effects on in situ photoactivation in the brain.

106 ciently generate radical PE lipids following photoactivation in the gas phase.

107 In contrast, PV photoactivation indirectly induced theta-band-limited, e

108 ements confirmed that in the nanodiscs, SRII photoactivation induces helix movement in the HtrII memb

109 ligand coordination environment of the first photoactivation intermediate, the photo-oxidized Mn3+ bo

110 The unstable photoactivation intermediates formed early in the photoa

111 in D1-D170E is due to the destabilization of photoactivation intermediates.

112 theory, the prevalence of two mechanisms of photoactivation (internal photoemission versus interband

113 According to the "two-quantum" model, photoactivation involves two light-driven charge separat

114 pectroscopic analysis suggests that PATagRFP photoactivation is a two-step photochemical process invo

115 tion-state structural data, reveals that OCP photoactivation is accompanied by a 12 angstrom transloc

116 also show that the opening of the OCP during photoactivation is caused by the movement of the C-termi

117 neration of the visual pigment following its photoactivation is critical for the function of cone pho

118 ion of Ca(2+), although the overall yield of photoactivation is enhanced by the additional Ca(2+).

119 n D1-D170E are heterogeneous with respect to photoactivation kinetics and that the majority of center

120 Photoactivation kinetics were assessed from the rate of

121 Their photoactivation led to cell death as measured by ion lea

122 Fluorescence photoactivation localization microscopy (FPALM) analyzes

123 ble-plane detection scheme with fluorescence photoactivation localization microscopy (FPALM) enabling

124 Fluorescence photoactivation localization microscopy (FPALM) images b

125 obtained using superresolution fluorescence photoactivation localization microscopy (FPALM) in nonpo

126 sed on a simple modification of fluorescence photoactivation localization microscopy (FPALM), polariz

127 Using quantitative high-speed fluorescence photoactivation localization microscopy (FPALM), we prob

128 oteins in mammalian cells using fluorescence photoactivation localization microscopy (FPALM).

129 luorescence (TIRF) microscopy, and live-cell photoactivation localization microscopy (PALM) demonstra

130 Photoactivation localization microscopy (PALM) is used t

131 tion microscopy methods such as fluorescence photoactivation localization microscopy and photoactivat

132 New work using high-speed fluorescence photoactivation localization microscopy now reveals the

133 This study uses single-particle tracking and photoactivation localization microscopy to analyze cell-

134 Here, we applied dual color photoactivation localization microscopy using photoactiv

135 (3D), super-resolution biplane fluorescence photoactivation localization microscopy with Eos-conjuga

136 Using fluorescence photoactivation localization microscopy, we are able to

137 ly formed spines, using a technique based on photoactivation localization microscopy.

138 Here, we used photoactivation, localization, and tracking in live Esch

139 Photoactivation may induce a rearrangement in this netwo

140 volved in the initial steps of the rhodopsin photoactivation mechanism and their optical spectra.

141 plored the role of this residue, Y21, in the photoactivation mechanism of the BLUF protein AppABLUF b

142 The photoactivation mechanism of the sensory rho-dopsin II (

143 n of a stable light state, consistent with a photoactivation mechanism that involves proton transfer

144 n adenine dinucleotide (FAD) and an internal photoactivation mechanism.

145 PAmCherry1 mutants, we propose the detailed photoactivation mechanism.

146 which is vital to determining the rhodopsin photoactivation mechanism.

147 ble progress has been made in uncovering the photoactivation mechanisms of both LOV and BLUF domains.

148 n design and a deeper understanding of their photoactivation mechanisms will allow the development of

149 These particles have been tested for photoactivation-mediated cytotoxicity using near-visible

150 , including conventional diffraction-limited photoactivation microscopy, super-resolution photoactiva

151 intercellular flux of small molecules using photoactivation microscopy.

152 To broaden photoactivation modalities, here we report a new strateg

153 Photoactivation occurs within a range of skin type model

154 Photoactivation of "snap-top" stoppers over the pore ope

155 ely occurs via a free-radical mechanism upon photoactivation of 1.

156 UVA photoactivation of 6-TG, ciprofloxacin and ofloxacin was

157 Photoactivation of a membrane-impermeant, fluorescent st

158 We also achieve 2P photoactivation of a metabotropic receptor, LimGluR3, wi

159 teria, the trigger for this mechanism is the photoactivation of a soluble carotenoid protein, the ora

160 sphopeptide product ions due to the infrared photoactivation of AI-ETD and show that modifying phosph

161 Photoactivation of aqueous chlorine could promote degrad

162 Here, using photoactivation of BDNF or syt-IV (a regulator of exocyt

163 n fact, these operating principles allow the photoactivation of BODIPY fluorescence with large bright

164 phototoxicity and emit UV light locally, for photoactivation of caged compounds and, in particular, u

165 The photoactivation of caged FAK peptide in 8-microm diamete

166 in a microfluidic device and illuminated for photoactivation of channelrhodopsin-2 to induce contract

167 assemblies is based on the enantio-selective photoactivation of chiral NPs and clusters, followed by

168 We found that photoactivation of ChR2 in genetically defined populatio

169 VTA photoactivation of ChR2-expressing mice reinforced instr

170 It is established that blue-light (BL) photoactivation of CRY is sufficient to depolarize and a

171 CL photoactivation of Cy7 azide in vitro showed significant

172 Furthermore, photoactivation of DAG itself was sufficient to induce t

173 Here, we demonstrate that UVA photoactivation of DNA S(4)TdR does not generate reactiv

174 a CL dose-dependent manner in vitro using CL photoactivation of DOX azide.

175 In the presence of diaminobenzidine (DAB), photoactivation of dye-filled vesicles yields an osmioph

176 ese metrics on units that were suppressed by photoactivation of either SOM(+) or PV(+) neurons.

177 turation, and antitumor immunity through the photoactivation of engineered chemokine receptors and ca

178 Direct photoactivation of excitatory neurons, which did not cha

179 tion of radical pairs of electrons requiring photoactivation of flavin adenine dinucleotide (FAD) bou

180 Profound transient photoactivation of G(i/o) signaling by (b)isoRho led to

181 c adenosine monophosphate, whereas transient photoactivation of G(q) signaling by (h)Mo enhanced worm

182 Local photoactivation of genetically targeted LiGluR, ChR2, or

183 mbomere 4 (r4) migratory stream by combining photoactivation of KikGR and confocal time-lapse analysi

184 at were biotinylated following rebinding and photoactivation of labeled GAPDH, aldolase, lactate dehy

185 feasibility of achieving cell-type-specific photoactivation of macaque neocortical neurons.

186 Here we report that nAcc photoactivation of mesoaccumbens glutamatergic fibers pr

187 We report the in vivo photoactivation of meta-azipropofol, a potent analog of

188 After photoactivation of mKikGR near the surface, rapid diffus

189 Photoactivation of monomeric rhodopsin.rHDL also results

190 -depolarizing optogenetic tools for targeted photoactivation of neuron firing.

191 ity for imaging thick specimens or selective photoactivation of neuronal networks.

192 Photoactivation of nonfluorescent NQMP-caged 3-allyloxyf

193 tachment of UV chromophores allows efficient photoactivation of not only the precursor ions but also

194 Finally, we show how photoactivation of opto-beta2AR in vivo modulates neuron

195 We demonstrate that photoactivation of PA-GFP is the result of a UV-induced

196 Furthermore, the photoactivation of paAIP2 expressed in amygdalar neurons

197 The photoactivation of paAIP2 in neurons for 1-2 min during

198 Photoactivation of paNPs in fatty acid-treated INS1 cell

199 Photoactivation of parvalbumin-positive interneurons (PV

200 We further show specific photoactivation of parvalbumin-positive interneurons in

201 We provide evidence that photoactivation of phy induces rapid in vivo phosphoryla

202 We found that photoactivation of PPTg glutamate cell bodies could serv

203 i1 diffusion using single-particle tracking, photoactivation of protein ensembles, and Monte Carlo si

204 Using targeted photobleaching and photoactivation of PSD subregions, we show that PSD-95 i

205 ns, nor did it prevent protrusion induced by photoactivation of Rac.

206 When a new lamellipodium was triggered with photoactivation of Rac1, the nucleus moved toward the ne

207 rent model for the formation of A2E requires photoactivation of rhodopsin and subsequent release of a

208 The translocation of Grb14 requires photoactivation of rhodopsin, but not signaling through

209 ring protracted (1-10 s) dark periods during photoactivation of Synechocystis cells.

210 oxygen and nitrogen species are generated by photoactivation of the anticancer platinum(IV) complex t

211 This transformation allowed the heterolytic photoactivation of the Ar-Cl bond in protic media and th

212 of this catalyst are ascribed to the in situ photoactivation of the BDDL surface during the photoelec

213 ically respond to hypercapnia or optogenetic photoactivation of the C4 cervical cord.

214 Photoactivation of the dark fluorogen leads to conversio

215 of charge reduced precursor ions or infrared photoactivation of the entire ion population concomitant

216 of the charge reduced precursors or infrared photoactivation of the entire ion population during the

217 tical electrophysiology, although blue light photoactivation of the FlicR1 chromophore presents a cha

218 The visual signaling pathway is initiated by photoactivation of the GPCR rhodopsin, which activates n

219 This mechanism is induced by photoactivation of the Orange Carotenoid Protein (OCP).

220 Thus, photoactivation of the recently developed neutral organi

221 without affecting novelty responses, whereas photoactivation of the same neurons reduces exploration

222 By single-cell photoactivation of the T cell antigen receptor (TCR), we

223 By single-cell photoactivation of the T cell antigen receptor, we show

224 Highly efficient photoactivation of the taxoid-tetrazoles inside the mamm

225 s recent advancements in the use of UCNs for photoactivation of therapeutic agents.

226 albumin GABAergic interneurons and that nAcc photoactivation of these fibers drove AMPA-mediated cell

227 Photoactivation of these long-lived, reactive states is

228 Photoactivation of these neurons reversed social avoidan

229 In addition, our results indicate that photoactivation of these projections modulates other beh

230 However, photoactivation of these terminals did not induce self-s

231 In sucrose operant conditioning, the photoactivation of these terminals increased nose-poking

232 Here, we exploit the selectivity of photoactivation of thiocarbonylthio compounds to impleme

233 Photoactivation of titanium dioxide nanoparticles (TiO2N

234 Sustained photoactivation of VALopA not only suppresses spontaneou

235 arried out by a signaling pathway that links photoactivation of visual pigments in retinal photorecep

236 Vision relies on photoactivation of visual pigments in rod and cone photo

237 We found that photoactivation of VTA glutamatergic neurons produced ro

238 Photoactivation of VTA slices from ChR2-expressing mice

239 Here, we test whether local photoactivation of VTA VGluT2 neurons expressing Channel

240 signaling properties of opsin, stemming from photoactivation or arrestin binding.

241 Super-resolution fluorescence imaging by photoactivation or photoswitching of single fluorophores

242 switchable tethered ligands (PTLs) to enable photoactivation, or photoantagonism, while preserving no

243 Supplemental infrared photoactivation outperforms collisional activation for m

244 After photoactivation, PAiRFPs slowly revert back to initial s

245 Photoactivation, patterning, and mechanical constraint o

246 rsor ions remains undissociated after the UV photoactivation period in order to prevent overdissociat

247 response across tone frequencies, whereas PV photoactivation preserved normal specificity of learning

248 ing rapid image acquisition and fluorescence photoactivation probes, we find that they exhibit locali

249 activation intermediates formed early in the photoactivation process were not, however, stabilized by

250 ArchT photoactivation produced similar BP changes in CaMKII-Ar

251 mismatched DNA sites specifically and, upon photoactivation, promote strand scission neighboring the

252 test this hypothesis, we used a fluorescence photoactivation pulse-escape technique to compare the ki

253 the pausing behavior, we used a fluorescence photoactivation pulse-escape technique to measure the ra

254 t for quantitative spectroscopic analysis or photoactivation purposes.

255 ze the active conformation of rhodopsin upon photoactivation (R*).

256 ion of cryptochrome supposedly arises from a photoactivation reaction involving radical pair formatio

257 ative imaging using fluorescence decay after photoactivation recordings of photoactivatable GFP-tagge

258 Under anesthesia, ArchT photoactivation reduced sympathetic nerve activity and B

259 ert back to initial state, enabling multiple photoactivation-relaxation cycles.

260 e originally described dark rearrangement of photoactivation, repetitive, double flash experiments, w

261 Photoactivation results in a slightly larger resilience

262 We propose a photoactivation scheme that maximally separates the acti

263 These complexes bind and with photoactivation selectively cleave DNA neighboring singl

264 f Synechocystis sp. PCC6803 cells undergoing photoactivation showed that basal fluorescence, F 0, exh

265 asurements of fluorescence dissipation after photoactivation showed that kinetochore-microtubule turn

266 Photoactivation significantly modifies the flexibility a

267 igment must fulfill many functions including photoactivation, spectral tuning, signal transmission, i

268 cells using cell fusion, photobleaching, and photoactivation strategies in combination with conventio

269 on proteins and then used photoconversion or photoactivation strategies to create distinct population

270 Photoactivation studies demonstrated irreversible adduct

271 Photoactivation studies suggest that the soluble pool of

272 ed proteins change little or not at all upon photoactivation, suggesting that rigid-body motions of h

273 developed a novel pulse-escape fluorescence photoactivation technique to investigate the long-term p

274 the MeRho-Az scaffold is less susceptible to photoactivation than other commonly used azide-based sys

275 UV-like pigment that displays less efficient photoactivation than the mouse short wavelength sensitiv

276 ocleavage experiments demonstrate that, upon photoactivation, the conjugate cleaves the DNA backbone

277 After photoactivation, the fluorophore is bright and photostab

278 On photoactivation, the OCP converts from a stable orange f

279 Upon photoactivation, the second messenger of phototransducti

280 Upon photoactivation, these probes can provide 10(4)-10(6) ph

281 ability of synaptically evoked spiking after photoactivation; this did not occur with a proton pump.

282 In-depth photoactivation through tissue phantoms and in vivo acti

283 nce recovery after photobleaching as well as photoactivation to determine Gag mobility.

284 ser-scanning microscopy and two-photon laser photoactivation to measure their rate of turnover in ind

285 stimulation parameters determined to confine photoactivation to targeted neurons, simultaneous excita

286 PhotoGate bypasses the requirement of photoactivation to track single particles at surface den

287 This same result was observed in photoactivation-tracking studies in which caged fluoresc

288 Finally, in both FCS and photoactivation-tracking studies, a temperature reductio

289 0V, were studied in terms of the kinetics of photoactivation under both continuous and flashing light

290 Photoactivation using single turnover flashes revealed D

291 with near diffraction-limited confinement of photoactivation using two-photon illumination and 3D loc

292 To define the structural basis of PAmCherry1 photoactivation, we determined its crystal structure in

293 further insights into structural details of photoactivation, we investigated the full-length Agp1 ba

294 Using photoactivation, we measured the movement of PA-GFP-TPX2

295 ge conformational changes in rhodopsin after photoactivation, we propose that ordered waters contribu

296 r thickness upon rhodopsin incorporation and photoactivation were mostly absent.

297 ations, neither opsin-arrestin complexes nor photoactivation were necessary for cell loss.

298 To facilitate deep-tissue photoactivation with near-infrared light, we measured th

299 After photoactivation with spatially restricted light, SPOT2.1

300 tes through state-selective (E and Z isomer) photoactivation with visible light.