ライフサイエンスコーパス: photoaging

1 CM), thereby promoting premature skin aging (photoaging).

2 a major determinant of premature skin aging (photoaging).

3 olar UV irradiation-induced premature aging (photoaging).

4 the pathophysiology of premature skin aging (photoaging).

5 and may contribute to premature skin aging (photoaging).

6 ich may provide potential prevention against photoaging.

7 E(2)) on HA-rich extracellular matrix during photoaging.

8 and anti-inflammatory effects of E(2) during photoaging.

9 ytes and fibroblast-based in vitro models of photoaging.

10 c target for the prevention and treatment of photoaging.

11 skin patterning is a sign of both aging and photoaging.

12 skin wrinkle formation in a murine model of photoaging.

13 possibility of using ERbeta as a target for photoaging.

14 tion associated with chronological aging and photoaging.

15 nm) (UVA) may cause photocarcinogenesis and photoaging.

16 raviolet (UV) light to human skin results in photoaging.

17 olecular mechanism in the pathophysiology of photoaging.

18 ies are directed at improving the results of photoaging.

19 ts in an old and wrinkled appearance, called photoaging.

20 let AI light (340 to 400 nm) associated with photoaging.

21 y and/or antioxidant activities, may prevent photoaging.

22 s-links might be useful markers of aging and photoaging.

23 s toxic intermediates in the pathogenesis of photoaging.

24 f compounds that protect against UVA-induced photoaging.

25 degrade skin collagen and may contribute to photoaging.

26 enzymes, as mediators of collagen damage in photoaging.

27 protection against skin cancer, sunburn, and photoaging, a genome-wide perspective of gene expression

28 alterations represent acute events, whereas photoaging and carcinogenesis are long-term consequences

29 trix proteins play a functional role in skin photoaging and carcinogenesis by sensitization of photo-

30 Radiation-induced skin damage ranges from photoaging and cutaneous carcinogenesis caused by UV exp

31 gnal transduction ultimately leading to skin photoaging and even skin cancer.

32 ene expression program associated with human photoaging and intrinsic skin aging (collectively termed

33 ved to underlie changes associated with both photoaging and natural aging, we determined whether natu

34 ers of oxidative stress underlying cutaneous photoaging and photocarcinogenesis, but the molecular id

35 n of reactive oxygen species contributing to photoaging and photocarcinogenesis.

36 Photoaging and skin cancer have been extensively studied

37 e clinically useful to prevent and/or reduce photoaging and skin cancer.

38 V light-based damage to skin cells can cause photoaging and skin cancer.

39 and should be useful for protection against photoaging and skin cancer.

40 a suggest a previously unreported pathway of photoaging and support the concept that photoaging is at

41 skin due to ultraviolet light from the sun (photoaging) and damage occurring as a consequence of the

42 solar UV radiation leads to premature aging (photoaging) and skin cancer.

43 rix may serve as markers for skin aging, for photoaging, and for immediate assessment of exposure to

44 e appropriate for mild, moderate, and severe photoaging, and in educating patients on the risks and b

45 iation (760-1440 nm) in dermal inflammation, photoaging, and photocarcinogenesis.

46 for skin cancer, prevent sunburns, mitigate photoaging, and treat photosensitive dermatoses.

47 or 2 mo on alternate days) following in vivo photoaging animal protocol.

48 Photocarcinogenesis and photoaging are established consequences of chronic expos

49 erienced in daily life, potentially promotes photoaging by affecting breakdown, rather than synthesis

50 Aging and photoaging cause distinct changes in skin cells and extr

51 n from sunlight causes premature skin aging (photoaging), characterized in part by wrinkles, altered

52 Solar UV irradiation causes photoaging, characterized by fragmentation and reduced p

53 vitamin D production but also leads to skin photoaging, damage, and malignancies.

54 UVA1 induction of MMP12 mediates some of its photoaging effects, particularly by contributing to elas

55 levance of using fibrillin-1 as a marker for photoaging, facial skin was biopsied at baseline and aft

56 determined whether natural skin aging, like photoaging, gives rise to increased matrix metalloprotei

57 on spectra of the physiological responses of photoaging has remained elusive.

58 This Commentary reports on the effects of photoaging in an experimental model of ultraviolet radia

59 To study UVA-induced photoaging in an in vivo system, we utilized a line of t

60 onses to ultraviolet light that eventuate in photoaging in human skin in vivo.

61 t, may also contribute to signs of premature photoaging in skin.

62 the use of mtDNA mutations as biomarkers of photoaging in the skin.

63 mechanisms by which ultraviolet light causes photoaging involve activation of growth factor and cytok

64 y of photoaging and support the concept that photoaging is at least in part a process of damage-accel

65 Photoaging is caused in part by damage to skin connectiv

66 Telangiectatic photoaging is characterized by less transient and nontra

67 Photoaging is the most common form of skin damage and is

68 exposure to the etiology of skin cancer and photoaging is undisputed.

69 Clinically chronic photoaging may result in fine wrinkles, texture abnormal

70 tiates chemical processes that result in the photoaging of skin.

71 Because retinoic acid (RA) can alter photoaging of the skin and repeated ultraviolet (UV)-ind

72 The premature photoaging of the skin is mediated by the sensitization

73 ccelerated by UV and with that contribute to photoaging of the skin.

74 umeric scales that include manifestations of photoaging other than rhytids, such as lentigines, hyper

75 rick skin type classification and the Glogau photoaging scale.

76 s may contribute to the clinical features of photoaging, such as wrinkle formation and loss of elasti

77 te multiple pathways underlying the cause of photoaging suggests ERbeta to be a novel therapeutic tar

78 etinoids are widely used in the treatment of photoaging to stimulate dermal repair.

79 of photoaging, which we term telangiectatic photoaging (TP).

80 effect of topical fluorouracil, 5%, cream on photoaging using validated photonumeric scales.

81 melanoma skin cancer (NMSC) and in cutaneous photoaging was explored using a genetic approach.

82 und to increase with aging and decrease with photoaging we investigated the characteristics of this d

83 mmunologic injury may play a role in chronic photoaging, we asked whether RA alters the acute photoim

84 arm of 16 subjects with a clinical range of photoaging were examined for fibrillin-1 and fibrillin-2

85 Individuals with clinically assessed severe photoaging were recruited to the study (n = 8).

86 idation in vivo in mouse skin, a hallmark of photoaging, when analyzed biochemically, by immunoblotti

87 Photoaging, which is premature skin aging caused by long

88 ultraviolet A radiation (UVA) contributes to photoaging, which results in the accumulation of massive

89 ngs can also be associated with a subtype of photoaging, which we term telangiectatic photoaging (TP)

90 his study did not demonstrate improvement in photoaging with a standard course of topical fluorouraci