ライフサイエンスコーパス: photocleavage

1 rst report of its production via bisretinoid photocleavage.

2 e fluorescent signal from Bodipy-650 and its photocleavage.

3 O2 is required for photocleavage.

4 xplain both the kinetics and products of the photocleavage.

5 For 1a,b, Phi(photocleavage) = 0.24-0.38, whereas Phi(photocleavage) =

6 se fluorescent tags can be removed easily by photocleavage after the identification of each nucleotid

7 and hybridization of DNA), sequence-specific photocleavage agents, and self-assembling components in

8 released from the solid-phase support by UV photocleavage and analyzed by capillary liquid chromatog

9 relation between the concentration-dependent photocleavage and enzymatic activities is also demonstra

10 enolic substituents (Y = CN, CF3, H) undergo photocleavage and release of 4-YC6H4OH with formation of

11 ving groups (LG) at the C-3 position undergo photocleavage and release of carboxylic acids with forma

12 lecule studies: lack of fluorophore mediated photocleavage and staining that does not perturb polymer

13 revealed both the structural implications of photocleavages and photoadduct formation.

14 anyl, indicated a different uranyl-dependent photocleavage as well.

15 mode of binding, versus that determined by a photocleavage assay described here (external stacking),

16 Using a photocleavage assay, mismatched sequences, and competiti

17 ntercalative binding, it is invisible to the photocleavage assay.

18 onstant and variable sequence contexts using photocleavage assays indicates that the recognition of b

19 Photocleavage assays reveal a several base pair region f

20 -quadruplex interaction (polymerase stop and photocleavage assays) and topoisomerase II interaction (

21 stent with a mechanism involving bisretinoid photocleavage at sites of singlet molecular oxygen addit

22 The P2VP coronas were readily removed by photocleavage at the ONB linker, leading to PFS cylinder

23 Agreement is found between photocleavage by the mismatch-specific probes and defici

24 Phi(photocleavage) = 0.24-0.38, whereas Phi(photocleavage) = ca. 0.05 for 1c.

25 Py-Phe in recognition and its minor role in photocleavage chemistry are demonstrated.

26 cross-linked peptides with on- and off-line photocleavage coupled with novel targeted data dependent

27 nder anaerobic conditions via Norrish Type I photocleavage during Pyrex filtered photolysis of the be

28 Proteins are released by photocleavage, eluted, and subsequently analyzed by quan

29 Although DNA photocleavage experiments demonstrate that their binding

30 DNA photocleavage experiments demonstrate that, upon photoac

31 Photocleavage experiments demonstrated that the modified

32 DNA photocleavage experiments reveal that all complexes bind

33 Laser photocleavage experiments revealed two ethidium-binding

34 Photocleavage experiments show that Rh(bpy)(2)(chrysi)(3

35 Photocleavage experiments were carried out to investigat

36 Copper cleavage experiments and photocleavage experiments with [Rh(phi)(2)bpy'](3+) comp

37 Through DNA photocleavage experiments, Rh(bpy)2(chrysi)3+ is shown t

38 ort the development of new methods, based on photocleavage, for the purification and printing of nasc

39 ether, these experiments suggest that uranyl photocleavage has been successfully used to probe cataly

40 Additionally, before photocleavage, immunogold can be employed to label prote

41 d from a ketone precursor via Norrish Type I photocleavage in a dinucleotide, single-stranded, and do

42 d from a ketone precursor via Norrish Type I photocleavage in single and double stranded RNA.

43 6 x 10(7) M(-1), respectively; site-specific photocleavage is evident at nanomolar concentrations.

44 The high specificity of photocleavage may be valuable in targeting specific site

45 ino group can be used as an affinity tag for photocleavage-mediated affinity purification and phospho

46 d three-dimensionally localized uncaging and photocleavage, not only in cell biology and neurobiology

47 hold formation method, which is based on the photocleavage of 2-nitrobenzyl linker-embedded DNA hairp

48 he method involves sequential Norrish Type I photocleavage of a ketone (7b) and beta-fragmentation of

49 ) in RNA oligonucleotides via Norrish type I photocleavage of a ketone-substituted nucleotide yields

50 rough independent spatiotemporally regulated photocleavage of crosslinks and photoconjugation of pend

51 Here we show how Norrish Type I photocleavage of dibenzyl ketone can be used to independ

52 Site-specific photocleavage of hen egg lysozyme and bovine serum album

53 Photocleavage of lysozyme and BSA was achieved with high

54 Quantum yields of photocleavage of lysozyme and BSA were 0.26 and 0.0021,

55 s have also been exploited, for example, for photocleavage of nucleic acids and for the destruction o

56 The compounds exhibited significant photocleavage of plasmid DNA upon visible light irradiat

57 sult is achieved by introducing radicals via photocleavage of residual photoinitiator in the polymer

58 The photocleavage of supercoiled DNA by (S)-A-62176 is unaff

59 only a fraction of the change caused by the photocleavage of the 2-nitrobenzyl groups.

60 ce increases by ~80% after the intracellular photocleavage of the 2-nitrobenzyl quenchers.

61 Under acidic conditions (pH = 2.5), photocleavage of the Ar-Cl bond occurred and a phenyl ca

62 Here, we show that photocleavage of the dynein heavy chain dramatically inh

63 We also systematically studied the photocleavage of the fluorescent dye from a DNA molecule

64 NA, detection of the fluorescent signal, and photocleavage of the fluorophore.

65 The photocleavage of the immobilized DNA was investigated di

66 C identical withN) is only observed from the photocleavage of the isomer 1a, whereas formation of the

67 Photocleavage of the labile linker was followed by direc

68 enzyl linker did not hinder the quantitative photocleavage of the linker in the DNA molecules.

69 Direct photocleavage of the oxalate linkage by laser flash phot

70 Norrish type I photocleavage of the tert-butyl ketone (2b) enabled stud

71 ctrophoresis reveals significantly less TOTA photocleavage of these quadruplex telomeric repeats when

72 ion of plasmid bioactivity, the presence and photocleavage of this relatively small number of cage gr

73 splaced strand, consistent with the observed photocleavage pattern.

74 Mass spectral analysis reveals different photocleavage products associated with the two binding m

75 The photocleavage products were characterized by HPLC and ma

76 Empty DR molecules generated by photocleavage rapidly bound peptide but quickly resolved

77 s, and inhibition studies, indicate that the photocleavage reaction occurs by a free radical mechanis

78 The (S)-A-62176-mediated DNA photocleavage reaction requires Mg(2+).

79 -A-62176 is much more efficient that the DNA photocleavage reactions of the fluoroquinolones norfloxa

80 photo-click reaction for bioconjugation and photocleavage reactions that allow for the removal of pr

81 nd mismatched DNA, but for these conjugates, photocleavage remains selective for the mismatched site,

82 RNase T(1) digestion and FMN photocleavage showed that circular permutation of the RN

83 f the resulting fragments indicated that the photocleavage sites of Py-D-Phe on BSA and lysozyme are

84 ly on the basis of structural models and DNA photocleavage studies of binding.

85 y-Phe isomers is further examined in protein photocleavage studies.

86 dramatically increased efficiency of ds DNA photocleavage, the most therapeutically valuable type of

87 borine is a cyclic carbamate which undergoes photocleavage, thus resulting in overall CO2 splitting.

88 h sites have been determined by quantitative photocleavage titration and yield values which vary from

89 base CA and CC mismatches, obtained through photocleavage titration or competition, vary from 10(4)

90 Photocleavage titrations reveal that the metal complex b

91 position, 5-phenylisothiazole also undergoes photocleavage to 2-cyano-1-phenylethenethiol which was t

92 ome dispersion) and to release the trap upon photocleavage to follow the cell's return to homeostasis

93 e specifically, nitrene 2 does undergo alpha-photocleavage to form benzoyl radicals and iminyl radica

94 Herein, we adopt uranyl photocleavage to probe specific uranyl-binding sites in

95 th: Photolabile molecular units that undergo photocleavage under light of different wavelengths can b

96 from a benzyl ketone (2a) via Norrish type I photocleavage upon irradiation at lambdamax = 350 nm.

97 The photocleavage was a general reaction, with the somewhat