ライフサイエンスコーパス: photodamage

1 e the efficiency of photosynthesis and avoid photodamage.

2 ture is in preventing biologically momentous photodamage.

3 tiphoton microscope while limiting potential photodamage.

4 ure by the photosynthetic antenna to prevent photodamage.

5 ndonuclease that makes an incision 5' to the photodamage.

6 ted by death receptors, lipid mediators, and photodamage.

7 dants may counteract and prevent UVR-induced photodamage.

8 e higher plant photosynthetic apparatus from photodamage.

9 ent a novel prophylactic approach to corneal photodamage.

10 -type Bcl-2 with respect to localization and photodamage.

11 ion over 20-30 min without photobleaching or photodamage.

12 sensitization of mitochondrial membranes to photodamage.

13 asia and considerably reduced penetration of photodamage.

14 maximizing the ability of the plant to avoid photodamage.

15 t their photosynthetic efficiency and induce photodamage.

16 ibution of laser-induced hyperthermia to the photodamage.

17 indicate the level of protection against DNA photodamage.

18 tributed to the higher bax:bcl-2 ratio after photodamage.

19 against psoralen plus ultraviolet A-induced photodamage.

20 n disorders and recommendations for reducing photodamage.

21 aging and avoids out-of-focus background and photodamage.

22 oninvasive and label-free and does not cause photodamage.

23 in the mutant is not strictly the result of photodamage.

24 effects on the rate of photosystem II (PSII) photodamage.

25 tes, producing singlet oxygen and subsequent photodamage.

26 ht to optimize light capture and to minimize photodamage.

27 the photochemical pathways leading to uracil photodamage.

28 , and lipid vesicles, without any detectable photodamage.

29 stunted growth and accumulation of apparent photodamage.

30 st be balanced to prevent photoinhibition or photodamage.

31 icated that these plants experience stronger photodamage.

32 atial resolution, low photobleaching and low photodamage.

33 to protect the photosynthetic system against photodamage.

34 thylakoid membranes and repair of PSII after photodamage.

35 fold, probably protecting it from UV-induced photodamage.

36 ults, who are at highest risk of ultraviolet photodamage.

37 al stress on skin, causing acute and chronic photodamage.

38 omain, spread diffusely in cells and was not photodamaged.

39 Bcl-2 missing alpha-helices 5/6 was also not photodamaged.

40 ic reticulum, and nuclear membranes and were photodamaged.

41 had significantly less clinical evidence of photodamage (0% graded 6-8 on a photonumeric scale) than

42 action center protein is the main target for photodamage(2), with repair involving the selective degr

43 ntation group A (XPA) to sites of nuclear UV photodamage, accelerating clearance of UV-induced photol

44 s of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing st

45 Our data also showed that DNA photodamage accumulates in both skin types with repeated

46 Overall, 22 men with significant photodamage and a high number of AKs were enrolled in th

47 (5)/alpha(6) region of Bcl-2 is required for photodamage and cross-linking, and domain-dependent phot

48 ntrol of DNA damage/repair and prevention of photodamage and nonmelanoma skin cancer in vitiligo.

49 luorescence and self-absorption, and reduced photodamage and photobleaching and therefore is particul

50 cutaneous melanocytes which protects against photodamage and photocarcinogenesis.

51 ynthetic ERbeta agonist inhibited UV-induced photodamage and skin wrinkle formation in a murine model

52 us, which could be a cause for the increased photodamage and subsequent D1 degradation.

53 the vulnerability of all genetic material to photodamage and subsequent mutations.

54 minated by D1a Symbiodinium experienced less photodamage and symbiont loss compared to control corals

55 th the redox state of the stroma rather than photodamage and that CGL71 functions under atmospheric O

56 similar action spectra for erythema and DNA photodamage and that erythema is a clinical surrogate fo

57 nvestigated type I procollagen production in photodamaged and sun-protected human skin.

58 include efficient background rejection, low photodamage, and improved depth discrimination.

59 htforward to implement, free of radiation or photodamage, and provide ample multiplexing capability,

60 e biologically relevant molecular targets of photodamage are still uncertain.

61 erable assembly complexes are protected from photodamage are unknown.

62 igmentation using erythema and epidermal DNA photodamage as endpoints.

63 dard course of fluorouracil on the extent of photodamage as measured using 4 photonumeric scales.

64 Pc 4-PDT photodamages Bcl-2 and Bcl-xL, antiapoptotic proteins in

65 nt of fluorescence leads to the reduction of photodamage, because the sample can be illuminated with

66 tistically significant changes were found in photodamage between baseline and 6 months (Griffiths sca

67 To assess DNA photodamage, biopsies were taken and prepared for paraff

68 synthetic apparatus of plants and algae from photodamage by dissipating as heat the energy absorbed i

69 ulation of photosynthesis, and in preventing photodamage by excess light.

70 se strategies minimize photosystem II (PSII) photodamage by keeping the photosynthetic electron trans

71 The molecular mechanisms of photodamage by ultraviolet A, the sunlight's major ultra

72 pecially in areas in which safety issues and photodamage by UV light are of concern.

73 at a substantial reduction of these types of photodamage can be achieved by imaging samples on covers

74 h as light scattering, autofluorescence, and photodamage can be reduced.

75 mporal resolution of and/or reduce potential photodamage caused by optical imaging in live neural tis

76 ed rate of damage entails an accumulation of photodamaged centers (80% of all PSII) and the formation

77 of the nanoparticles and may further repair photodamaged conjugated polymer.

78 Using a new photodamage criterion based on morphological changes of

79 stem II, likely by affecting turnover of the photodamaged D1 polypeptide.

80 tion as a protease in the degradation of the photodamaged D1 protein, they also are required, either

81 for in all organisms by enzymatic repair of photodamaged DNA.

82 nd a six- to 20-fold decrease in the rate of photodamage during calcium imaging of rat hippocampal br

83 e to study cellular processes because of low photodamage, efficient background rejection, and improve

84 xygenase system is a risk factor for retinal photodamage, especially in individuals with Stargardt di

85 hibition is always observed when the rate of photodamage exceeds the rate of D1 repair.

86 The action spectrum for photodamage exhibits minima at 830 and 970 nm, and maxim

87 uous pigmented facial macules and 12 control photodamaged facial areas were included in the study.

88 The rate of photodamage for 0615 and 0518 is 3.5 and 2.5 times that

89 ctions as a rapid and sensitive model of UVA photodamage for the identification and comparison of com

90 ( approximately 65 and 57%, respectively) in photodamaged forearm skin compared to sun-protected hip

91 ced capacity of skin fibroblasts in severely photodamaged forearm skin to synthesize procollagen, or

92 Photodamage from this pigment is minimized by its short

93 UVA photodamage has been attributed to photosensitization by

94 pe I and type III procollagen are reduced in photodamaged human skin.

95 l fluorescence measurements revealed no PSII photodamage in chilled leaves of either genotype.

96 e have determined the action spectra for DNA photodamage in different human epidermal layers in situ.

97 Histologically, there was less evidence of photodamage in ETR than in TP, which had wispy collagen

98 different spectral profiles, to inhibit DNA photodamage in human epidermis in situ.

99 decreasing the severity of acute and chronic photodamage in human skin.

100 This agent induces photodamage in irradiated cells and simultaneously ident

101 r: transient growth arrest and repair of DNA photodamage in keratinocytes (KCs); elimination of KCs w

102 ave established that optical tweezers induce photodamage in live cells, the effects of trap irradiati

103 We tested for laser-induced photodamage in several ways.

104 poptotic member of the Bcl-2 family, was not photodamaged in Pc 4-PDT-treated human carcinoma cells M

105 A on the apoptotic response to mitochondrial photodamage induced by photodynamic therapy (PDT).

106 developed to quantify ATR-pS435, measure XPA-photodamage interactions, and assess NER function.

107 s higher plant photosynthetic machinery from photodamage, is triggered by acidification of the thylak

108 This finding has implications for disease/photodamage mechanisms and interventions.

109 ing technology, signal generation rates, and photodamage mediation are bringing us closer to the goal

110 Photodamage, observed on Western blots as the loss of th

111 ed stomach mucosa of anesthetized mice while photodamage of gastric epithelial surface cells created

112 This causes photodamage of labeled proteins and rapid photobleaching

113 evel of PSI does not result from accelerated photodamage of the PSI centers in var1 or var2 under mod

114 200 micro m) into tissue slices with minimal photodamage of tissue and photobleaching of label.

115 f photoprotection by examining the effect of photodamage on the behavior of a switchable mutant of ki

116 submicron resolution and little out-of-focus photodamage or bleaching, its ability to record fast ele

117 be attributable to a true lack of effect in photodamage or limitations of the photonumeric scales in

118 x that also serves to protect Rubpy dye from photodamaging oxidation, the Rubpy-dye-doped nanoparticl

119 erobic conditions, implicating oxygen in the photodamage pathway.

120 zing, and thereby minimizing the dynamics of photodamage (PD), a frequent limiting factor in the opti

121 Photodamage peaks in the UV-B part of the spectrum, but

122 To avoid photodamage, photosynthetic organisms are able to therma

123 This was accompanied by repair of photodamaged photosystem II (PSII) reaction centers, acc

124 and processes associated with the repair of photodamaged photosystem II complexes is discussed.

125 unassembled thylakoid membrane proteins and photodamaged photosystem II D1 protein.

126 n, may render it vulnerable to unprecedented photodamage, possibly involving nonadjacent bases that a

127 ore photoproduct or SP) is the exclusive DNA photodamage product in bacterial endospores.

128 ore photoproduct or SP) is the exclusive DNA photodamage product in bacterial endospores.

129 his study we pursue a closer analysis of the photodamage promoted on giant unilamellar vesicles membr

130 PSII) core complex, and may act in repair of photodamaged PSII complexes.

131 vo biosynthesis and/or assembly of D1 in the photodamaged PSII template.

132 The accumulation of photodamaged PSII under irradiance stress reflects a chl

133 Repair of photodamaged PSII was not affected by gabaculine.

134 I) reaction center protein D1 upon repair of photodamaged PSII.

135 with a rate over five times higher than its photodamage rate and has a maximum reaction yield exceed

136 vel target for the prevention of UVB-induced photodamage regardless of p53 status.

137 lumination, suggesting that Deltapsi-induced photodamage represents a previously unrecognized limitin

138 Localized photodamage resulted in rapid cell exfoliation coinciden

139 markedly reduces overall photobleaching and photodamage, resulting in extended viability of biologic

140 mine, circumvents the limitations imposed by photodamage, scattering, and indiscriminate background e

141 To better understand DNA photodamage, several nucleosides were studied by femtose

142 gen, or whether contextual influences within photodamaged skin act to down-regulate type I procollage

143 For these studies, fibroblasts from photodamaged skin and matched sun-protected skin were es

144 d underlie the loss of collagen synthesis in photodamaged skin and, to a lesser extent perhaps, in ag

145 Pigmented facial macules on photodamaged skin are a clinical, dermoscopic, and histo

146 False-positives obtained with RCM in photodamaged skin are due to the presence of basal melan

147 In contrast, cells in photodamaged skin are often in contact with fragmented c

148 therefore, that factors within the severely photodamaged skin may act in some manner to inhibit proc

149 n of partially degraded collagen observed in photodamaged skin may inhibit, by an as yet unidentified

150 Collagen synthesis is reduced in severely photodamaged skin relative to collagen synthesis in corr

151 ollagen is approximately 3.6-fold greater in photodamaged skin than in sun-protected skin, and some f

152 udy of ambiguous pigmented facial macules on photodamaged skin was conducted in a tertiary referral c

153 confocal microscopy improves LM diagnosis in photodamaged skin with good histopathologic correlation

154 In photodamaged skin, collagen fibrils are shortened, thinn

155 Melanoma arising in chronically photodamaged skin, especially on the head and neck, is o

156 es in collagen structure in vivo in aged and photodamaged skin.

157 ches were used to assess collagen changes in photodamaged skin.

158 f these patients, there is neither increased photodamage/skin aging nor a higher incidence for sun-in

159 re susceptible to all-trans-retinal-mediated photodamage than are the major proteins from the rod out

160 ton fluorescence microscopy causes much less photodamage than conventional confocal microscopy, expan

161 chloroplasts exhibit greater photosystem II photodamage than is observed in the wild type, particula

162 skin (MED) is a more useful predictor of DNA photodamage than is racial/ethnic origin or skin phototy

163 ochondria was considerably more sensitive to photodamage than was Bcl-xL in the cytosol, indicating t

164 titute a previously unrecognized type of DNA photodamage that may interfere with telomere replication

165 hat erythema is a clinical surrogate for DNA photodamage that may lead to skin cancer.

166 to UV radiation are subject to irreversible photodamage through covalent modification of tryptophans

167 Employing this assay, we characterized photodamage throughout the near-infrared region favored

168 Photodamage to ABCR causes it to aggregate in SDS gels a

169 We now observe Pc 4-PDT-induced photodamage to all Bcl-xL-related proteins, except the 3

170 mage and cross-linking, and domain-dependent photodamage to Bcl-2 offers a unique mechanism for activ

171 (TC50 > 400 muM) and high ability to induce photodamage to endothelial cells (EA.hy926) without prei

172 At a 50 mJ/cm2 light dose, photodamage to MCF-10A/bcl-2 resulted in a greater loss

173 Photosynthetic organisms avoid photodamage to photosystem II (PSII) in variable light c

174 enotype of npq1 lor1 was not due to enhanced photodamage to photosystem II but rather to a less local

175 Photodamage to phycobilisomes in vitro and in living cel

176 hich presumably diminishes the likelihood of photodamage to reaction centers that have either lost an

177 r and protein in the complex or irreversible photodamage to the aptamer.

178 activation yield by suppressing irreversible photodamage to the cofactor-free apo-WOC-PSII (photoinhi

179 that acute disruption of synaptic ribbons by photodamage to the ribbon markedly reduced both sustaine

180 Tumors and photodamaged tumor-free "margin" skin were obtained from

181 e to the large penetration depth and reduced photodamage, two-photon imaging is an highly promising t

182 analyzed the amount and distribution of DNA photodamage using RIAs and immunofluorescence micrograph

183 arison of cell shape in 1-microm sections of photodamaged versus healthy skin at the light microscopi

184 d antenna complexes become protected against photodamage via shortening of the excited-state lifetime

185 Photodamage was determined to be negligible by observing

186 in Outcomes and Measures: Resolution of skin photodamage was evaluated on clinical examination.

187 The intensity dependence for photodamage was linear, supporting a single-photon proce

188 thesis, life expectancy was <40 y; long-term photodamage was not a concern; and vitamin D(3) deficien

189 lity of these mice as a model of UVA-induced photodamage, we administered four lotions to the skin of

190 To characterize the requirements for photodamage, we transiently transfected epitope-tagged B

191 Their skin photodamage were also improved or resolved completely on

192 The RNA nucleobase uracil can suffer from photodamage when exposed to UV light, which may lead to

193 oscopy, we demonstrate substantially reduced photodamage when imaging rapid morphological changes in

194 Several mechanisms exist to avoid photodamage, which are collectively referred to as nonph

195 omplex consisting of AKAP12-ATR-pS435-XPA at photodamage, which is essential for cAMP-enhanced NER.

196 rce is crucial for protection of PSI against photodamage, which occurred particularly during the high

197 ltraviolet (UV) light, bears the majority of photodamage, which results in skin thinning, wrinkling,

198 The location of DNA photodamage within the epidermis is crucial as basal lay

199 hat there may be specific protein targets of photodamage within the outer segment, and they may be es