ライフサイエンスコーパス: photosensitivity

1 utaneous responses to ultraviolet radiation (photosensitivity).

2 ed by progeriod features, growth failure and photosensitivity.

3 t high light intensities because of enhanced photosensitivity.

4 nistic Ox-GPCs in the pathophysiology of XPA photosensitivity.

5 d neurological disease and nonmalignant skin photosensitivity.

6 ed oxidative damage may mediate the observed photosensitivity.

7 icles with similar asymmetric morphology and photosensitivity.

8 in erythrocytes, skin, and liver, and acute photosensitivity.

9 ut mice resulted in restoration of circadian photosensitivity.

10 planted mice showed minimal evidence of skin photosensitivity.

11 reatment was associated with a selective UVA photosensitivity.

12 o prevent liver disease and significant skin photosensitivity.

13 e group had a higher incidence of nausea and photosensitivity.

14 ster formation (especially in childhood) and photosensitivity.

15 tibody positivity followed by malar rash and photosensitivity.

16 not of melanopsin expression, decreased iris photosensitivity.

17 tability, CRY-TIM interaction, and circadian photosensitivity.

18 melanopsin, a photopigment that confers this photosensitivity.

19 e most common adverse event was dose-related photosensitivity.

20 out specific potential toxicities, including photosensitivity.

21 d neither polyneuropathy nor exacerbation of photosensitivity.

22 develop cancer, although they often exhibit photosensitivity.

23 s into the plasma and results in severe skin photosensitivity.

24 for rare heritable disorders associated with photosensitivity.

25 ritis, Raynaud's phenomenon, malar rash, and photosensitivity.

26 ntiation, and others an increase in cellular photosensitivity.

27 sual thalamus only in epilepsy patients with photosensitivity.

28 ased OPN4X photopigment conferring intrinsic photosensitivity.

29 tabolism frequently characterized by extreme photosensitivity.

30 h larvae with chd2 knockdown were tested for photosensitivity.

31 rkedly enhanced mild innate zebrafish larval photosensitivity.

32 e defective transcription-coupled repair and photosensitivity.

33 odystrophy (TTD), which share only cutaneous photosensitivity.

34 ffective erythropoiesis and devastating skin photosensitivity.

35 the most part only associated with increased photosensitivity.

36 eginning of outer-segment disc formation and photosensitivity.

37 is responsible for hemolytic anemia and skin photosensitivity.

38 hotosensitive patients and in people without photosensitivity.

39 ge, but the drug dose required and cutaneous photosensitivity.

40 etaxel plus vandetanib arm and included rash/photosensitivity (11% v 0%) and diarrhea (7% v 0%).

41 ); (ii) genetic generalized epilepsy without photosensitivity, 13 patients (mean age 25 +/- 11 years)

42 luded: (i) genetic generalized epilepsy with photosensitivity, 16 subjects (mean age 25 +/- 10 years)

43 first criterion (34.5%); it was followed by photosensitivity (18.8%).

44 %-2%), blue-gray skin discoloration (4%-9%), photosensitivity (25%-75%), hypothyroidism (6%), hyperth

45 vs 15 [4%]), anorexia (37 [11%] vs 13 [4%]), photosensitivity (42 [12%] vs 6 [2%]), rash (111 [32%] v

46 tients, 48%), nausea (58 patients, 45%), and photosensitivity (52 patients, 40%).

47 ficantly reduced allergen-induced changes in photosensitivity (60%, P = 0.0002), chemosis (50%, P = 0

48 ), malar rash (56.0%), discoid rash (34.2%), photosensitivity (60.9%), and oral/nasal ulcerations (43

49 se change may be used to alter the degree of photosensitivity, although there is limited information

50 Defective NER is associated with photosensitivity and a high skin cancer incidence.

51 rties including high electron mobility, high photosensitivity and an excellent electron accepting nat

52 ential mechanisms of voriconazole-associated photosensitivity and carcinogenesis and identify areas t

53 Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients

54 bnormal OS morphology and reduced single rod photosensitivity and dark currents.

55 Melanopsin is required for ipRGC photosensitivity and for behavioural photoresponses that

56 Here we investigate the intrinsic photosensitivity and functioning of HCs from primary cul

57 While mechanisms of photosensitivity and genetic underpinnings associated wi

58 FS syndrome highlight the high prevalence of photosensitivity and hair and nail disorders.

59 f heme biosynthesis that manifests as severe photosensitivity and hepatotoxicity.

60 photosystem I (PSI) accumulation, exhibited photosensitivity and highly reduced abundance of PSI und

61 V-induced DNA damage is associated with skin photosensitivity and increased skin cancer risk.

62 rotoporphyrin in amounts sufficient to cause photosensitivity and liver disease.

63 lated Malacosteus genes were associated with photosensitivity and may relate to its unique visual eco

64 a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback

65 essential and synergistic roles in affecting photosensitivity and OS morphogenesis of rod photorecept

66 ent and insensitive but by P6 show increased photosensitivity and persistence.

67 Photosensitivity and photosensitization could be demonst

68 the mechanism linking this mutant protein to photosensitivity and poikiloderma remains to be determin

69 ition, but it has been complicated by severe photosensitivity and polyneuropathy.

70 The most common adverse events were photosensitivity and rash.

71 Thus, T lymphocytes possess intrinsic photosensitivity and this property may enhance their mot

72 It is characterized clinically by acute photosensitivity and, in 2% of patients, liver disease.

73 ion by skin (leading to protracted cutaneous photosensitivity); and less than optimal photophysical p

74 Erythema, photosensitivity, and immunologic alterations represent

75 characterized by osteoskeletal deformities, photosensitivity, and increased osteosarcoma susceptibil

76 tic disease characterized by skin fragility, photosensitivity, and increased risk of squamous cell ca

77 iciency of photosynthetic electron transfer, photosensitivity, and lethality in soil.

78 with defects in the TTDN1 gene: four had no photosensitivity, and one patient exhibited cutaneous bu

79 (ACR) criteria of malar rash, discoid rash, photosensitivity, and oral ulcers, and 3 (23%) met the m

80 s of human rhodopsin's spectral sensitivity, photosensitivity, and regeneration kinetics.

81 n brain pacemaker cells increases behavioral photosensitivity, and this restricted CRY expression als

82 Several features of ipRGC photosensitivity are characteristic of fly photoreceptor

83 The causes of photosensitivity are diverse, ranging from primary, immu

84 ted phospho-rhodopsin has the same molecular photosensitivity as unphosphorylated rhodopsin and that

85 loss of Ro function could contribute to the photosensitivity associated with anti-Ro antibodies in h

86 hat these Ox-GPCs play a pivotal role in the photosensitivity associated with the deficiency of the D

87 Heterozygous mice exhibited skin photosensitivity but no liver disease.

88 othesize that a mechanism to suppress pineal photosensitivity by using NE released from sympathetic n

89 Some clinical treatments that cause photosensitivity can also increase skin cancer risk.

90 Thereafter, full recovery of photosensitivity coincides with regeneration and dephosp

91 mice demonstrate paradoxically increased PLR photosensitivity compared with mice mutant in visual cyc

92 Photosensitivity could also be prevented locally by impl

93 The same parameters, together with a fixed photosensitivity, could account for the steady-state pig

94 In addition to increased photosensitivity, CS patients suffer from severe develop

95 Genetic generalized epilepsy with photosensitivity demonstrated significantly greater mean

96 esis of a number of skin disorders including photosensitivity diseases and some types of cutaneous ma

97 s of carotenoids on cardiovascular diseases, photosensitivity diseases, cataracts, and age-related ma

98 ough the differential diagnosis of pediatric photosensitivity disorders is broad, it is often possibl

99 The bioinspired photosensitivity enhancer (BPE) that we have developed e

100 Cones recover their photosensitivity faster than rods after bleaching.

101 e events were grade 1 or 2 arthralgia, rash, photosensitivity, fatigue, and alopecia.

102 tinas and isolated cone cells show increased photosensitivity following exposure to blue light.

103 Rash and photosensitivity frequencies were higher in the simeprev

104 y was reported in the 1.0 mg/kg cohort (skin photosensitivity [grade 2]).

105 patients at a TPCS2a dose of 1.5 mg/kg (skin photosensitivity [grade 3] and wound infection [grade 3]

106 syndrome (CS) is characterized by increased photosensitivity, growth retardation, and neurological a

107 be uncovered, the literature on disorders of photosensitivity has been otherwise without many recent

108 a single infusion, no instances of cutaneous photosensitivity have been noted in these patients.

109 New developments in the field of pediatric photosensitivity have been scant over recent years.

110 Based on their intrinsic photosensitivity, HCs may have a key dual function in th

111 a premature aging disorder characterized by photosensitivity, impaired development and multisystem p

112 We then determined the heritability of photosensitivity in 420 individuals from families ascert

113 in complete and long-term correction of skin photosensitivity in all transplanted mice.

114 e, however, is too slow to explain sustained photosensitivity in bright light.

115 A new paper provides direct evidence of photosensitivity in cerebrospinal fluid (CSF)-contacting

116 to topical or systemic agents may also cause photosensitivity in children.

117 determined whether CHD2 variation underlies photosensitivity in common epilepsies, specific photosen

118 nique CHD2 variants are also associated with photosensitivity in common epilepsies.

119 The development of photosensitivity in culture could be partially or comple

120 ic mechanism for the regulation of circadian photosensitivity in Drosophila.

121 Across 58 pedigrees the prevalence of photosensitivity in first-degree relatives was 20.9% com

122 unidentified direction toward achieving high photosensitivity in imaging systems.

123 d rhodopsin, retinoids, phosphorylation, and photosensitivity in mice during a 90 min illumination fo

124 Photosensitivity in most echinoderms has been attributed

125 d polyspike wave discharges, with documented photosensitivity in most.

126 evious complementation studies show that the photosensitivity in nearly all of the studied patients i

127 de-containing DNA, providing a mechanism for photosensitivity in RNase H2-associated SLE.

128 n achieving low discrete dark noise and high photosensitivity in rod pigments for dim-light vision.

129 hotochemical quenching, leading to increased photosensitivity in the mutant plants under light stress

130 Photosensitivity in the pediatric patient is caused by a

131 As-grown heterostructures exhibit inherent photosensitivity in the visible light spectrum with high

132 n two-photon fluorescent imaging or enhanced photosensitivity in two-photon sensitization, respective

133 Rat RGCs that exhibited intrinsic photosensitivity invariably expressed melanopsin.

134 te cutaneous lupus erythematosus (SCLE), and photosensitivity is a common symptom.

135 for a scientific commentary on this article.Photosensitivity is a condition in which lights induce e

136 Photosensitivity is a heritable abnormal cortical respon

137 Importantly, circadian photosensitivity is increased in a cry-overexpressing st

138 We find that all ipRGC photosensitivity is melanopsin dependent.

139 P synthase pgr5 double mutant, a decrease in photosensitivity is observed compared with the single AT

140 Clinical photosensitivity is present in approximately 50% of TTD

141 Photosensitivity is prominent in a very rare epileptic e

142 In single rods of Rp1L1-/-, photosensitivity is reduced, similar to that of Rp1-/-.

143 hototransistors with high and broad spectral photosensitivity is reported.

144 se role of melanopsin in supporting cellular photosensitivity is unconfirmed.

145 tery occlusion, and (3) the possibility that photosensitivity may have a role in the pathogenesis of

146 001) and had earlier onset of photosensitivity (mean [SD] age, 35.5 [3.9] vs 47.5 [2.9

147 r cellular content estimated previously from photosensitivity measurements and retinal extraction yie

148 keratoacanthoma or squamous-cell carcinoma, photosensitivity, nausea, and diarrhea; 38% of patients

149 Rash, photosensitivity, nausea, vomiting, and diarrhea were th

150 Photosensitivity occurred more frequently with acetylcys

151 In parallel, we tested the photosensitivity of an ascorbate-deficient xanthophyll c

152 phorylation of the CCE domain determines the photosensitivity of Arabidopsis CRY2.

153 lustrated by the observation that the strong photosensitivity of Chlamydomonas reinhardtii cells depl

154 ranscribed strand accounts for the increased photosensitivity of CS patients, the reason for developm

155 k per second reveals an unexpected degree of photosensitivity of fluorophore-containing cells.

156 method to significantly improve the overall photosensitivity of imaging systems.

157 ine, it was possible to estimate the in vivo photosensitivity of mouse rhodopsin to be about 6 x 10(-

158 Photosensitivity of PDT-treated cells was measured by a

159 ase that is linked, at least in part, to the photosensitivity of PKCepsilon transgenic mice.

160 Under the in vitro conditions, the photosensitivity of RGR is at least 34% that of bovine r

161 opsin mutants, to improve the unusually high photosensitivity of rhodopsin are proposed.

162 The photosensitivity of Rlbp1(-/-) mice is normal but rhodop

163 PSs), optimal drug release profiles, and the photosensitivity of surrounding tissues.

164 We demonstrate that the photosensitivity of the C60 nanorods can be enhanced ~40

165 The photosensitivity of the carbon monoxide complex of myogl

166 acellular milieu, concomitant with a reduced photosensitivity of the cells.

167 lso commensurate with the relative long-term photosensitivity of the corresponding solids and solutio

168 al day 10 (P10); however, the development of photosensitivity of the ipRGCs remains largely unexplore

169 he same genotype, and that for the intrinsic photosensitivity of the melanopsin-expressing retinal ga

170 The visual pigments that underlie the photosensitivity of the retina have been examined in a n

171 hich is likely to directly contribute to the photosensitivity of these patients.

172 We find that the photosensitivity of this circuit is conferred by vertebr

173 RBCs and urine, as well as reversion of skin photosensitivity on bortezomib treatment.

174 trainment, and either their melanopsin-based photosensitivity or ability to relay rod/cone input is s

175 ns capable of alleviating porphyrin-mediated photosensitivity or decoupling dieting and fasting from

176 etely recovered to have had fever, headache, photosensitivity, or neck stiffness during their acute i

177 Photosensitivity, or photoparoxysmal response (PPR), is

178 A 44-year-old man developed blurry vision, photosensitivity, orthostasis, constipation, and acrodys

179 American Indian ancestry protected against photosensitivity (P < 0.0001, OR 0.58 [95% CI 0.44-0.76]

180 TLR3 rs3775296-T was associated with photosensitivity (p = 0.0020) and anemia (p = 0.0082).

181 myelination with calcium deposits, cutaneous photosensitivity, pigmentary retinopathy and/or cataract

182 myelination with calcium deposits; cutaneous photosensitivity; pigmentary retinopathy, cataracts, or

183 utaneous porphyrias with skin blistering and photosensitivity: porphyria cutanea tarda; congenital er

184 The prevalence of photosensitivity (predominantly polymorphic light erupti

185 tion provides a connection between cutaneous photosensitivity, protein damage, and increased skin can

186 ancestry were significantly associated with photosensitivity (Ptrend=0.0021, odds ratio for highest

187 though the major symptom of this disorder is photosensitivity, rarely, it can cause progressive liver

188 s were reported by six patients and included photosensitivity, rash, and headache.

189 thralgia (1259 [39%]), fatigue (1093 [34%]), photosensitivity reaction (994 [31%]), alopecia (826 [26

190 livered immediately after the first, but its photosensitivity recovered slowly in the dark, a process

191 ght responsive from birth (P0) and that this photosensitivity requires melanopsin expression.

192 ging, telangiectasia, neurodegeneration, and photosensitivity, resulting from a homozygous missense (

193 neurological dysfunction, cachetic dwarfism, photosensitivity, sensorineural hearing loss, and retina

194 xeroderma pigmentosum variant show clinical photosensitivity, skin neoplasias induced by ultraviolet

195 </= 24 h with FosPEG 2% and 8%, whilst skin photosensitivity studies showed Foscan(R) induces more d

196 subsequently enabled them to attain the low photosensitivity tailored to the role of circadian recep

197 phylaxis include hyperkalemia, hypoglycemia, photosensitivity, thrombocytopenia, and more rare advers

198 tinal ganglion cells (ipRGCs) combine direct photosensitivity through melanopsin with synaptically me

199 ory and functional significance of intrinsic photosensitivity through the vertebrate lineage and also

200 ion and the availability of azo-dopants with photosensitivity throughout the entire visible spectrum,

201 Melanopsin imparts an intrinsic photosensitivity to a subclass of retinal ganglion cells

202 -type counterparts and displayed the typical photosensitivity to high light associated to phylloquino

203 imary, immunologically mediated disorders of photosensitivity to inherited genetic or metabolic disor

204 The photopigment melanopsin confers photosensitivity upon a minority of retinal output neuro

205 cytes and hepatocytes, and resulting in skin photosensitivity upon leaching of blood protoporphyrin i

206 also to the regulation of other events whose photosensitivity varies during a diurnal cycle.

207 In this study, cortical function in photosensitivity was assessed using two visual aftereffe

208 Photosensitivity was more common with vemurafenib (14 pa

209 Iris photosensitivity was not affected by retinoid depletion

210 A wider action spectrum of intrinsic photosensitivity was obtained than would be expected for

211 Photosensitivity was present in 75% of the patients and

212 ntestinal disorders, jaundice, dry skin, and photosensitivity were increased at 240 mg BID compared w

213 unconjugated hyperbilirubinemia, and rash or photosensitivity were more common in the active groups t

214 onformational flexibility, and increased the photosensitivity, which indicates a local effect in the

215 anced cortical excitability in subjects with photosensitivity, which is likely to reflect changes in

216 s (>/=18 years) undergoing investigation for photosensitivity who were diagnosed with CAD from Novemb

217 ver, the double mutant exhibits an increased photosensitivity with respect to the single mutants and

218 s: All 3 cases reported a rapid reduction in photosensitivity within weeks following initiation of sy

219 otosensitive epilepsies and individuals with photosensitivity without seizures.