ライフサイエンスコーパス: phototropin

1 f inhibition is delayed in seedlings lacking phototropin.

2 small family of photoreceptors known as the phototropins.

3 ins are the light-sensitive portion of plant phototropins.

4 tion between the LOV2 domain of Avena sativa phototropin 1 (AsLOV2) and an engineered PDZ domain (ePD

5 The LOV2 domain of Avenasativa phototropin 1 (AsLOV2), a member of the Per-Arnt-Sim (PA

6 tch based on the LOV2 domain of Avena sativa phototropin 1 (AsLOV2).

7 and activate the phototropism photoreceptors phototropin 1 (phot1) and phototropin 2 (phot2) by using

8 calcium (Ca2+) that begins within seconds of phototropin 1 (phot1) excitation is believed to be an im

9 Phototropin 1 (phot1) is a Ser/Thr photoreceptor kinase

10 radiation by a mechanism that depends on the phototropin 1 (phot1) photoreceptor.

11 ly photoactive LOV2 domain from Avena sativa phototropin 1 and the Escherichia coli trp repressor.

12 action between Arabidopsis phytochrome A and phototropin 1 at the plasma membrane.

13 en, voltage) of the blue light photoreceptor phototropin 1 from Avena sativa (oat).

14 glutamine residue [Q513 in the Avena sativa phototropin 1 LOV2 (AsLOV2) domain] switches its hydroge

15 the model plant Arabidopsis thaliana, phot1 (phototropin 1) is the dominant receptor controlling phot

16 sponses along with the protein kinase PHOT1 (Phototropin 1).

17 n the C-terminal LOV2 domain of Avena sativa phototropin 1, formation of this bond triggers a conform

18 Arabidopsis thaliana) mutants lacking either phototropins 1 and 2 (phot1 and phot2) or cryptochromes

19 ism photoreceptors phototropin 1 (phot1) and phototropin 2 (phot2) by using energy from absorbed blue

20 Phototropin, a major blue-light receptor for phototropis

21 a paralogue of the NPH1 gene, which encodes phototropin, a photoreceptor for phototropic bending.

22 Light plays a crucial role in activating phototropins, a class of plant photoreceptors that are s

23 ntrolled by light-activated kinases known as phototropins, a group of kinases that contain two light-

24 a series of still poorly understood events, phototropin activation leads to the formation of a gradi

25 te the magnitude of curvature resulting from phototropin activation.

26 ate phototropism through the coaction of the phototropin and cryptochrome blue-light photoreceptors.

27 large-scale phylogenetic reconstructions of phototropin and phytochrome gene families.

28 o the regulation by the blue light receptors phototropin and plant cryptochrome (pCRY).

29 utant, in which phot2 is the only functional phototropin and PP2A activity is reduced, showed enhance

30 In contrast, we also demonstrate that phototropins and cryptochromes function together to enha

31 Based on our results, we hypothesize that phototropins and cryptochromes regulate phototropism by

32 proteins that were first described in plant phototropins and form a subgroup of the Per-Arnt-Sim (PA

33 as light-sensory modules in plant and algal phototropins and in fungal blue-light receptors.

34 signaling mechanism, YtvA differs from plant phototropins and more closely resembles prokaryotic heme

35 ant neochromes, a chimera of phytochrome and phototropin, appear to share a common origin.

36 tochrome 1 (cry1), cryptochrome 2 (cry2) and phototropin are the blue/ultraviolet-A light receptors t

37 The phototropins are a family of membrane-associated flavopr

38 The phototropins are flavoprotein kinases that control photo

39 Phototropins are light-activated kinases important for p

40 Phototropins are plasma-membrane-associated UV-A/blue-li

41 omains, first identified in the higher-plant phototropins, are now shown to be present in plants, fun

42 was engineered from the blue light receptor phototropin as a reporter of viral infection.

43 nal arises through binding and coaction with phototropin at the plasma membrane.

44 iates physically with another photoreceptor, phototropin, at the plasma membrane.

45 The resulting phototropin autophosphorylation is essential for biologi

46 and how the phytochromes, cryptochromes, and phototropins bring about changes in development seen in

47 s not homogeneous, the uncovered phytochrome-phototropin co-action is important for plants to adapt t

48 We restored this dysfunction in different phototropin complementation experiments.

49 egration of light signals sensed through the phototropin, cryptochrome, and phytochrome signaling pat

50 t the nph4 mutants fail to exhibit the basal phototropin-dependent and phyA-dependent enhancement res

51 This pathway is under the control of the phototropin-dependent blue-light signaling cascade and c

52 e demonstrate that NPH3 is not necessary for phototropin-dependent growth inhibition.

53 the plasma membrane and displays light- and phototropin-dependent localization to microfilaments in

54 rowth inhibition that replaces the transient phototropin-dependent phase after approximately 30 min o

55 onse is genetically separable from the basal phototropin-dependent response, as demonstrated by its r

56 As phototropins do not influence circadian gene expression

57 Signaling from phototropin during the curvature response is dependent u

58 egative phototropism that is mediated by the phototropin family of photoreceptors.

59 blue light receptor, phot1, a member of the phototropin family, is a plasma membrane-associated flav

60 ependent formation of a C-terminal truncated phototropin form was observed.

61 plications of this mechanism with respect to phototropin function are discussed.

62 gate the role of LOV1 and LOV2 in regulating phototropin function.

63 we also discovered a previously unidentified phototropin gene that likely represents the ancestral li

64 Studies of the plant phototropins have identified 11 flavin-contacting residu

65 ing maintenance, opposite to the function of phototropin in these processes.

66 These results suggest that phototropin-induced actin bundling via THRUMIN1 is impor

67 This result indicates that BL-activation of phototropin influences cryptochrome signaling leading to

68 hototropism1) mutant, which lacks one of the phototropin-interacting CPT proteins, shows reduced sens

69 Phototropin is a blue-light receptor involved in the pho

70 We propose that phototropin is a light regulator of phototaxis that dese

71 Moreover, phototropin is involved in adjusting the level of channe

72 Light sensing by the phototropins is mediated by a repeated motif at the N-te

73 the presumed signaling species that leads to phototropin kinase activation and subsequent signal tran

74 f a peripheral Jalpha helix and, ultimately, phototropin kinase activation.

75 Complementation with the phototropin kinase fragment reduced the eyespot size, in

76 by dual receptors such as phytochrome B and phototropin leads to immediate signalling convergence.

77 significance for the different roles of the phototropin LOV domains is discussed.

78 in adapts a structure similar to that of the phototropin LOV domains.

79 eveals that a family of blue photoreceptors, phototropins, maintain robust rhythms of Fq'/Fm' under c

80 The UV-A/blue light sensing phototropins mediate several light responses enabling op

81 results highlight the strict specificity of phototropin-mediated signal transduction pathways.

82 sents the ancestral lineage of the neochrome phototropin module.

83 ses red-sensing phytochrome and blue-sensing phototropin modules into a single gene, thereby optimizi

84 th drastically enlarged chloroplasts, and in phototropin mutants with impaired photorelocation but no

85 e blue light (BL) requires the action of the phototropin (nph1) BL receptor.

86 The present work demonstrates that phototropin (nph1), the photoreceptor responsible for ph

87 phy3) LOV2 are conserved in LOV domains from phototropin of other plant species and from three protei

88 These constructs encode either wild-type phototropin or phototropin with one or both LOV-domain c

89 from the marine picoalga Ostreococcus tauri phototropin (Otphot) and examine its ability to replace

90 aracterized the light-dependent changes of a phototropin PAS domain by solution nuclear magnetic reso

91 ion of the spectrum, while cryptochromes and phototropins perceive blue and UVA light.

92 ght photoreceptors, cryptochrome (CRY) 2 and phototropin (PHOT) 2, are required for the stability of

93 In flowering plants, the phototropin (phot) blue light receptors are essential to

94 Phototropin (PHOT) is a photoreceptor involved in a vari

95 Phototropins (phot) sense blue light through the two N-t

96 Phototropin (phot1) is a blue light-activated plasma mem

97 Phototropins (phot1 and phot2) are autophosphorylating s

98 Phototropins (phot1 and phot2) are blue light receptor k

99 Phototropins (phot1 and phot2) are plant blue-light rece

100 Phototropins (phot1 and phot2), the plant blue-light rec

101 These photoresponses are mediated by two phototropins, phot1 and phot2.

102 entified THRUMIN1 as a critical link between phototropin photoreceptor activity at the plasma membran

103 Phototropin photoreceptors (phot1 and phot2 in Arabidops

104 s stimulated by blue light perceived via the phototropin photoreceptors and is transduced to the acti

105 sis (Arabidopsis thaliana) is induced by the phototropin photoreceptors and modulated by the cryptoch

106 c analyses indicate that the cryptochrome or phototropin photoreceptors do not participate in the res

107 maging and genetic experiments revealed that phototropin photoreceptors stimulate katanin-mediated se

108 The phototropin photoreceptors transduce blue-light signals

109 ption, including the phytochrome (Phy) A and phototropin photoreceptors.

110 nse is mediated by blue/UV A light-absorbing phototropins (phots) and cryptochromes (crys).

111 Phototropins (phots) regulate a range of adaptive proces

112 Of the two phototropins present in the model plant Arabidopsis thal

113 When placed into the full-length phototropin protein, these point mutations display const

114 nt in regulation of kinase signaling for the phototropin proteins.

115 ses of fungi through madA and plants through phototropin rely on diverse proteins; however, these pro

116 Residues that interact with FMN in the phototropin segment of the chimeric fern photoreceptor (

117 rystal structure of the LOV2 domain from the phototropin segment of the chimeric fern photoreceptor p

118 in Physcomitrella protonemata binds several phototropins specifically in the photoactivated Pfr stat

119 ctive LOV (light oxygen voltage) domain from phototropin, sterically blocking Rac1 interactions until

120 (R)/far-R (FR) regions and cryptochromes and phototropins that respond to the ultraviolet-A/blue (B)

121 imilar to the LOV domains found in the plant phototropins, the Neurospora VIVID (VVD) protein, and th

122 We therefore propose the name phototropin to designate the nph1 holoprotein.

123 ry portion of phot1 leads, as in other plant phototropins, to activation of a C-terminal serine/threo

124 In response to blue light, phototropins undergo autophosphorylation.

125 Previous studies indicated that phototropin uses a bound flavin mononucleotide (FMN) wit

126 strain in which the blue light photoreceptor phototropin was deleted by homologous recombination, the

127 0A mutant of the LOV2 domain of Avena sativa phototropin was reconstituted with universally and site-

128 ors that mediate chloroplast movements (i.e. phototropins), we conducted a mutant screen that has led

129 in that binds flavin mononucleotide in plant phototropins, we show that light responses are abolished

130 during the light period are downregulated by phototropin, whereas the level of channelrhodopsin-2 is

131 phototropism is primarily controlled by the phototropins, which are also involved in stomatal moveme

132 ructs encode either wild-type phototropin or phototropin with one or both LOV-domain cysteines mutate

133 rs, such as phytochromes, cryptochromes, and phototropins, ZEITLUPE (ZTL), FLAVIN-BINDING, KELCH REPE