ライフサイエンスコーパス: physical function

1 articipants (62% female, 30% with restricted physical function).

2 /or nerve function), and 6-minute-walk test (physical function).

3 issue and systemic inflammation and enhanced physical function.

4 ance to most patients, such as cognitive and physical function.

5 reast cancer may experience deterioration of physical function.

6 ) and improves cardiorespiratory fitness and physical function.

7 other patient-reported outcomes (PROs), and physical function.

8 betes, or to participants with moderate/high physical function.

9 disability with vision-related function and physical function.

10 are potentially protective against declining physical function.

11 lth behaviors, other chronic conditions, and physical function.

12 ears (QALYs) and improvements in fatigue and physical function.

13 and differentiation is necessary to maintain physical function.

14 s of rheumatoid arthritis and improvement in physical function.

15 sment of the patient's emotional, social and physical function.

16 reduction in pain and >/=10% improvement in physical function.

17 without the confounding effects of impaired physical function.

18 rance were nonmodifiable factors linked with physical function.

19 e without the confounding impact of impaired physical function.

20 body composition, bone mineral density, and physical functions.

21 e exercise and fitness, skills learning, and physical functioning.

22 ficits, but many reported impaired school or physical functioning.

23 literacy and greater pain and limitations in physical functioning.

24 disability in this population with impaired physical functioning.

25 ith short-term effects on pain intensity and physical functioning.

26 ic status, relationship (couple) status, and physical functioning.

27 r age at operation was associated with worse physical-functioning (-0.4/yr, P = 0.008).

28 s APT, fatigue -1.22, 95% CI -0.52 to -1.97, physical function 1.54, 0.86 to 2.31; GET vs APT, fatigu

29 s APT, fatigue -1.37, 95% CI -0.76 to -2.21, physical function 1.90, 1.10 to 2.91), but not CBT.

30 t mediated via total count of comorbidities: physical functioning 17.8% [men] versus 7.7% [women] and

31 ; GET vs APT, fatigue -1.86, -0.80 to -2.89, physical function 2.35, 1.35 to 3.39).

32 -0.48 point [CI, -0.82 to -0.14 point]) and physical functioning (2 RCTs; MD, 2.50 [CI, 0.90 to 4.10

33 , 0.20-1.03]) and in the score for the SF-36 physical functioning (22.4 [99% CI, 16.3-28.5] vs 12.6 [

34 .29-0.33), and they showed an improvement in physical functioning (36-Item Short Form Health Survey p

35 istically significant (adjusted estimate for Physical Functioning = 4.2, p = 0.14; for Role Physical

36 ited or no evidence of disease, specifically physical function (41.1 v 46.6, respectively), fatigue (

37 ain interference (52.4), fatigue (52.2), and physical function (44.1).

38 ioning and memory), as well as 2 measures of physical functioning (a Short Physical Performance Batte

39 Yet the impact of LT on physical function, a main determinant of quality of life

40 cts completed surveys about their visual and physical functioning ability.

41 gue, anxiety, depression, sleep disturbance, physical function, ability to participate in social role

42 tremity pain had greater odds of having poor physical function according to scores on the Health Asse

43 Trial, we examined incident deterioration of physical function after 12 months, defined as a >/= 10-p

44 ype (p<0.05) were associated with changes in physical functioning; age was associated with changes in

45 r, may play an important role in maintaining physical function among older adults.

46 of a confirmatory study designed to preserve physical function among survivors of breast cancer.

47 ervention in critical illness, be focused on physical function and assessed months or even years afte

48 measurements of physical performance assess physical function and associate with mortality and disab

49 Our results emphasize the importance of physical function and body composition in estimating TDE

50 esity exacerbates the age-related decline in physical function and causes frailty in older adults; ho

51 homocysteine, folate, and vitamin B-12 with physical function and decline in older persons.

52 e, and length; base of support), self-report physical function and disability, and falls in the past

53 nt provides clinically important benefits in physical function and disease-specific measures of quali

54 The level of physical function and disuse is often associated with ag

55 ion should be evaluated for their effects on physical function and frailty.

56 s associated with substantial impairments in physical function and health-related quality of life tha

57 s associated with substantial impairments in physical function and health-related quality of life tha

58 ween LR and OR, but the LR results in better physical function and less surgical site infections than

59 Improvements in physical function and mental health are evident in the 2

60 Physical function and mental health improved over time;

61 Factors that were associated with physical function and mental health outcomes over time t

62 ere used to identify factors associated with physical function and mental health over time.

63 reater likelihood of no major limitations in physical function and mental health.

64 's malignant disease, resulting in declining physical function and other detrimental clinical consequ

65 ides superior pain relief and improvement in physical function and patient's global assessment versus

66 mortality, length of hospital and ICU stay, physical function and quality of life, muscle strength,

67 have musculoskeletal pain that limits their physical function and quality of life.

68 Impaired physical function and reduced physical activity are comm

69 uromuscular weakness and impairments in both physical function and related aspects of quality of life

70 In addition, the physical function and vitality domains of the SF-36 Heal

71 joint models of longitudinal trajectories of physical function and waiting list mortality adjusted fo

72 ssessed associations of cognition with later physical functioning and associations of physical functi

73 ssociation between peripheral neuropathy and physical functioning and how the longitudinal associatio

74 rs with three or more late effects had lower physical functioning and Karnofsky score, lower likeliho

75 st bidirectional associations of memory with physical functioning and less evidence of associations o

76 served among patients with low self-reported physical functioning and low functional exercise capacit

77 adequacy was associated with improvements in Physical Functioning and Role Physical of 7.3 (p = 0.02)

78 At 6-month follow-up, adjusted increases in Physical Functioning and Role Physical scores for every

79 e, peak expiratory flow, in combination with physical functioning and symptom information more readil

80 ularly memory, is associated with subsequent physical functioning and vice versa.

81 bodily pain, 76.5% (95% CI, 74.6%-78.5%) for physical function, and 59.5% (95% CI, 56.4%-62.7%) for w

82 s, end-stage renal disease, quality of life, physical function, and activities of daily living.

83 cations, including muscle weakness, impaired physical function, and decreased health-related quality

84 en emphysema and key measures of physiology, physical function, and health care use.

85 ongitudinal epidemiology of muscle weakness, physical function, and health-related quality of life an

86 ndomized to device for total physical score, physical function, and in physical role limitation compa

87 l and psychological symptom burden, impaired physical function, and inferior survival compared with t

88 to older patients, such as quality of life, physical function, and maintenance of independence.

89 es: cognition, muscle and/or nerve function, physical function, and pulmonary function.

90 us, and evaluated global nutritional status, physical function, and quality of life before and after

91 vity would increase fat-free mass, strength, physical function, and quality of life, and reduce the r

92 comes were muscle power and quality, overall physical function, and total body and thigh compositions

93 mprovement, compared with baseline, in pain, physical function, and walk time over 3 years, but the p

94 l aging and included resilience, depression, physical functioning, and age (entering the regression m

95 urveys collect self-reported data on health, physical functioning, and biomarkers.

96 stance due to deterioration in cognition and physical functioning, and changes in behavior.

97 uding incidence of chronic diseases, memory, physical functioning, and mental health, among populatio

98 ysical component indicated low self-reported physical functioning, and the first question of the SF-1

99 (TSMBs) on the experienced pain and fatigue, physical functions, and mental focus of surgeons.

100 (TSMBs) on the experienced pain and fatigue, physical functions, and mental focus of surgeons.

101 composition, bone mineral density, specific physical functions, and quality of life.

102 Incident depressive symptoms and impaired physical function are common and long-lasting during the

103 at reported a measure of muscle structure or physical function as an outcome measure.

104 l SAQ domains including angina frequency and physical function, as well as the role physical and role

105 Physical function assessed at baseline, 6 months (ie, at

106 ed by the Chalder Fatigue Questionnaire) and physical function (assessed by the Short Form-36 physica

107 Physical function assessments were available for 86% of

108 Physical function at 1 month follow-up did not significa

109 se program resulted in modest improvement in physical function at 6 months after randomization.

110 eriod (for global health status at 9 months, physical functioning at 8 weeks, cognitive functioning a

111 ng: maximal leg strength, timed chair stand, physical function battery, gait characteristics (speed;

112 nia, even in those with normal cognition and physical function before pneumonia (beta = -0.02; P < 0.

113 mptoms within 3-5 years of age and declining physical functions before attaining puberty.

114 y (57%) showed no significant differences in physical function between groups.

115 Detailed body composition, physical function, biochemistry, and genotype data were

116 l-being with subscales that address not only physical functioning but also psycho-social issues.

117 pain and to 70.2% (95% CI, 67.8%-72.5%) for physical function, but improvement rates for walk time,

118 late host regenerative processes and improve physical function by regulating long noncoding RNA in re

119 (CBT p = 0.0027; GET p = 0.0059) and better physical function (CBT p=0.0002; GET p<0.0001).

120 sed comprehensively, including cognitive and physical function, coexisting medical conditions, demogr

121 s criteria to be designated as core domains: physical function, cognition, mental health, survival, p

122 nce, emotional well-being and relationships, physical function, cognitive function, or spirituality.

123 e nursing home model has positive effects on physical function compared to traditional nursing homes.

124 oids associated with improvement in pain and physical function compared with sham injection or no int

125 onths, the YG group had greater increases in physical functioning compared with both ST and WL groups

126 on antihypertensive medication had impaired physical functioning compared with other LT patients.

127 ssociated with a significant increase in the physical functioning component of the SF-36 score.

128 he covariate-adjusted mean difference on the physical function composite was -1.5 (95% confidence int

129 Physical functioning, constipation, and dyspnea were ind

130 Impaired physical functioning correlated with decreased left ante

131 the percentage with improvement in pain and physical function decreased between year 1 and year 3.

132 Secondary outcomes included physical function, depression, medication use, and quali

133 ion of participants who experienced incident physical function deterioration after 12 months was 16.3

134 ve weight lifting to reduce the incidence of physical function deterioration among survivors of breas

135 with standard care reduced the incidence of physical function deterioration among survivors of breas

136 models to determine whether trajectories of physical functioning differed by prevalent neuropathy st

137 Higher Short-Form-36 physical functioning domain scores at the prior visit we

138 rated the greatest odds of difficulty with 3 physical function domains, including activities of daily

139 Better physical functioning during recovery predicted subsequen

140 ey measures of PTSD; work, role, social, and physical functioning; employment; and poverty.

141 provided potential benefits with respect to physical function, fatigue, urinary problems, hot flashe

142 y and durability of improvements in pain and physical function following Roux-en-Y gastric bypass (RY

143 all, LT had a positive and durable effect on physical function for both older and younger recipients.

144 ncy and is a valid and responsive measure of physical function for ICU patients.

145 duals with cerebral palsy seek, not improved physical function for its own sake.

146 Mean improvement in physical function for the surgery and PT groups was 22.4

147 ICU admission is associated with decreased physical function for years after discharge.

148 ificant, with key sex-specific inferences on physical function, frailty, disability, and pharmacodyna

149 = 0.40, 95% confidence interval 0.08, 0.71), physical function (g = 0.46, 95% confidence interval 0.1

150 mpared objective and self-report measures of physical function, gait patterns, and falls between wome

151 < 0.001), and improved the QoL parameters of physical functioning, general health, vitality, social f

152 iation between purpose in life and objective physical function has not been examined.

153 aracteristics, income, health, cognitive and physical function, health behaviors, subjective beliefs

154 poorer self-rated health, mental health, and physical functioning, higher probability of smoking, and

155 everyday-activities domains of the Migraine Physical Function Impact Diary (scale transformed to 0 t

156 de of ACR responses and disease activity and physical function improvements were comparable between t

157 s in acute lung injury, studies of long-term physical function in acute lung injury survivors have co

158 a reliable, valid, and responsive measure of physical function in acute respiratory distress syndrome

159 RDA (2RDA) affects skeletal muscle mass and physical function in elderly men.In this parallel-group

160 letal radiographs and improved pulmonary and physical function in infants and young children with lif

161 uding reducing IMAT) and muscle strength and physical function in obese elderly, but those with highe

162 ng (RT) improves muscle strength and overall physical function in older adults.

163 ulted in modest improvement in self-reported physical function in patients with hip and knee osteoart

164 There were impacts on emotional, social, and physical functioning in both conditions.

165 the interrelationships between cognitive and physical functioning in older adults is critical to dete

166 s have important implications for health and physical functioning in older age, and physical activity

167 y reduce cancer-related symptoms and improve physical functioning in patients with RCC.

168 (APT) or SMC alone in improving fatigue and physical functioning in people with chronic fatigue synd

169 lls played a synergistic role in cardiac and physical functions in the aged monkeys by regulation of

170 mental activities of daily living ("impaired physical function") in patients without baseline impairm

171 aire, in which higher scores indicate better physical function, increased more in the diet-exercise g

172 wait time and low baseline MELD; decline in physical function is associated with an increased risk o

173 association between sedentary activities and physical function is context specific (TV viewing vs. co

174 erence was statistically significant for the physical function item which was lower.

175 Secondary end points included physical function, knee function (WOMAC function scale,

176 Chronic inflammation may fuel declines in physical function leading to frailty and disability.

177 Peripheral neuropathy may play a role in physical functioning limitations and future disability.

178 This is important because poor physical function may be associated with premature morta

179 e, 1.6 units [95% CI, 0.9 to 2.3 units]) and physical function (mean difference, 9.3 units [CI, 5.9 t

180 ction, the longitudinal trajectories of each physical function measure were significantly associated

181 ue measured by the Chalder fatigue scale and physical function measured by the physical function subs

182 by Chalder fatigue questionnaire score) and physical function (measured by short form-36 subscale sc

183 unctional Status Score for the ICU and other physical function measures, and generally weaker correla

184 g correlations (69% of 32 > 0.40) with other physical function measures.

185 tion of other parameters, such as lifestyle, physical functioning, mental symptoms, and physical symp

186 lso demonstrated significant improvements in physical function [MOS SF-36 PCS (Medical Outcomes Study

187 ns and in interpreting studies comparing the physical function of groups of ICU patients.

188 he effects of PS on the body composition and physical function of older people undergoing RET.We perf

189 ms and, to a lesser degree, on sexuality and physical functioning of patients with breast cancer expe

190 and global status as well as improvement in physical function on the Short Form 36 (SF-36) physical

191 ous impact of the longitudinal trajectory of physical function on waiting list mortality (=death or d

192 Primary endpoint was physical function, one of the dimensions of the Short Fo

193 ition, no differences were seen in objective physical function or depressive symptoms at 12 months in

194 iseases or major impairments in cognitive or physical function or mental health).

195 iseases or major impairments in cognitive or physical function or mental health.

196 than 275 ng/mL and impaired sexual function, physical function, or vitality were allocated to testost

197 values, for 6-minute-walk distance and SF-36 Physical Function outcome measures.

198 s associated with improved mental health and physical function over time.

199 re deteriorated less (for pain P = 0.05; for physical function P = 0.02).

200 SF-36 subscales favored the LR group: physical function (P < 0.001), role physical (P < 0.012)

201 tality (P < 0.001; 95% CI, 0.96-0.98), daily physical function (P < 0.001; 95% CI, 0.97-0.99), and pa

202 vely, there were significant improvements in physical function (P = .02), energy and fatigue (P = .00

203 cardiorespiratory fitness (P < .001), better physical functioning (P </= .001), less nausea and vomit

204 sity (P=0.02), and interference of pain with physical functioning (P=0.02) on discharge from the serv

205 g New York Heart Association class (P=0.05), physical functioning (P=0.03), and physical health compo

206 ur (p=0.01), family activities (p<0.001) and physical functioning (p=0.05).

207 f the SF-36, with large differences for role physical function, pain, and the physical component summ

208 ficant benefit in improving quality of life, physical function, peripheral and respiratory muscle str

209 The declines in cognitive and physical function persisted for at least 8 years.

210 aluation of cognition, depression, distress, physical function (PF) (self-reported and objectively me

211 res included diet quality (DQ), PA, BMI, and physical function (PF).

212 sed diseases and completed the Short Form 36 physical functioning (PF) scale over multiple survey cyc

213 Physical functioning (PF; QLQ-C30) and eating problems (

214 h pretransplantation functional status data (physical function [PF] scale of the Medical Outcomes Stu

215 Form Health Survey (SF-36) domain scores for physical functioning, physical role functioning, bodily

216 a, and similar trajectories of cognitive and physical function prior to pneumonia (adjusted prevalenc

217 Baseline NCF tests and the physical functioning quality of life scale were associat

218 distance was the primary outcome; markers of physical function, quality of life, health status, and d

219 husetts General Hospital (MGH) Cognitive and Physical Functioning Questionnaire (CPFQ) showed a promi

220 comes Study 36-Item Short-Form Health Survey physical functioning questionnaires were also administer

221 comes Study 36-Item Short-Form Health Survey physical functioning questionnaires were also administer

222 s with the corresponding SF-36 Health Survey physical function (r=-0.87), vitality (r=-0.85), and sho

223 Physical functioning reduced in the first month after su

224 nitive functioning but worse on 1 measure of physical functioning relative to children born full term

225 Patients with limited physical function reported more physical/psychological (

226 Improvements in fatigue and physical functioning reported by participants originally

227 ined (within-group comparison of fatigue and physical functioning, respectively, at long-term follow-

228 -up period compared with 1 year (fatigue and physical functioning, respectively: APT -3.0 [-4.4 to -1

229 s of adding CR for weight loss on muscle and physical function responses to RT in older overweight an

230 ns were also found between weight change and physical function, role limitations due to physical prob

231 bscales (fatigue, nausea and vomiting, pain, physical functioning, role functioning, disease symptoms

232 dy 36-Item Short-Form Health Survey (SF-36): physical functioning; role limitations due to physical h

233 01 to 1.24; P = .03), abnormal Short Form-36 physical function (RR, 1.19; 95% CI, 1.06 to 1.33; P < .

234 the 36-item Short-Form health survey (SF-36; physical function scale only) at week 14.

235 e, 1.1 [95% CI, 0.04 to 2.1, P = .04), SF-36 physical function scale score (difference, 12.2 [95% CI,

236 s (SF-36) for physical and mental health and physical function scale score, Functional Performance In

237 n 24 months after surgery, measured with the physical functioning scale of the European Organisation

238 s 64% (+/- 22%) and 67% (+/- 26%), and SF-36 Physical Function score (as percent-predicted) was 61% (

239 e best proprioceptive acuity, whose pain and physical function score deteriorated less (for pain P =

240 The baseline mean (SD) physical function score for the active group was 32.3 (9

241 Primary outcome was physical function score on the Short Form-36 Health Surv

242 o -2.3, p<0.0001; effect size 0.53) and mean physical function score was 55.7 (23.3) in the GES group

243 minute-walk distance, and Short Form [SF]-36 Physical Function score) for 203 survivors of ALI enroll

244 er Universities Osteoarthritis Index (WOMAC) physical-function score (ranging from 0 to 100, with hig

245 C pain scores (0.47 on a 20-point scale) and physical function scores (by 1.5 points on a 0-68-point

246 Compared with SMC alone, mean physical function scores were 7.1 (2.0 to 12.1) points h

247 No significant differences in SF-36 physical function scores were observed between patients

248 of life was similar between groups, whereas physical functioning scores remained slightly lower in p

249 AQ scores, lower Short Form 36 health survey physical functioning scores, lower composite SPPB scores

250 s: 0.729, 0.750, and 0.740 for self-reported physical functioning, self-rated general health, and fun

251 Secondary outcomes were objective physical function (Short Physical Performance Battery) a

252 ave proposed that loss of muscle strength or physical function should also be included in the definit

253 rhage, cognitive function, and self-reported physical function showed good calibration.

254 emotional and social functioning; caregiver physical functioning significantly worsened.

255 ted had significantly greater improvement in physical function, social function, and quality of life.

256 athy Questionnaire (KCCQ) (23 items covering physical function, social function, symptoms, self-effic

257 fect of heart failure on patients' symptoms, physical function, social limitations, and QOL.

258 We assessed self-reported physical function status with the Health Assessment Ques

259 e, higher perceived behavioural control, the physical function subscale of SF-36, and having someone

260 s, defined as a >/= 10-point decrease in the physical function subscale of the Medical Outcomes Short

261 scale and physical function measured by the physical function subscale of the SF-36.

262 aster Universities OA Index (WOMAC) Pain and Physical Function subscale scores of >/=5 and >/=4, resp

263 ical function (assessed by the Short Form-36 physical function subscale); both were self-rated by pat

264 ge (CGIC), the change in 36-Item Short Form- physical functioning subscale score (SF-36), and the cha

265 n the deutetrabenazine group, the mean SF-36 physical functioning subscale scores decreased from 47.5

266 the SF-36 physical component summary and the physical functioning subscale) was significantly worse a

267 unctioning (36-Item Short Form Health Survey physical functioning subscale; P=.002; effect size, 0.37

268 e from baseline to week 16 in WOMAC Pain and Physical Function subscales and patient's global assessm

269 , compared with placebo, GM-CSF improved the physical functioning subscore of the SF-36 questionnaire

270 timore (N=255) and AT1RaAb associations with physical function tests and outcomes assessed.

271 effective in reducing fatigue and improving physical function than both adaptive pacing therapy (APT

272 nhibition of joint damage and improvement in physical function than does MTX alone.

273 and exercise provides greater improvement in physical function than either intervention alone.

274 umin, hepatocellular carcinoma, and baseline physical function, the longitudinal trajectories of each

275 ficantly between the two study groups in the Physical Function Trial but did differ significantly whe

276 three trials--the Sexual Function Trial, the Physical Function Trial, and the Vitality Trial.

277 provement in pain and a small improvement in physical function up to 6 weeks after injection.

278 We also assessed pain, stiffness, and physical function using the Western Ontario and McMaster

279 ence that associations between cognitive and physical functioning varied over time.

280 The physical functioning, vitality (energy/fatigue) and soci

281 Physical function was assessed using self-report measure

282 Physical function was assessed with the Australia-modifi

283 The SF36 Physical function was found to be a suitable primary out

284 In both groups, physical function was reduced yet significantly improved

285 For example, 5 years after surgery, physical function was stable or improved in 86% of patie

286 Physical functioning was measured in 1996-2008 using tim

287 At 6 and 12 months, "physical function" was in favor of the younger group (3

288 improvement in joint and skin responses and physical function, was maintained through 1 year.

289 cidences of depressive symptoms and impaired physical function were 40 and 66%, respectively, with gr

290 Risk factors for incident impaired physical function were longer ICU stay and prior depress

291 e, higher income, more education, and higher physical functioning were independently associated with

292 important difference [MCID], 1.8 units) and physical function (Western Ontario and McMaster Universi

293 m, no pain; 100 mm, worst pain possible) and physical function (Western Ontario and McMaster Universi

294 alking (11-point numerical rating scale) and physical function (Western Ontario and McMaster Universi

295 essed on a numerical rating scale [NRS]) and physical function (Western Ontario and McMaster Universi

296 Treatment should target full return to physical function, which leads to subsequent improvement

297 face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic ob

298 eletal muscle that may contribute to reduced physical function with knee OA-associated muscle disuse,

299 tioning and less evidence of associations of physical functioning with executive functioning and glob

300 ter physical functioning and associations of physical functioning with later cognition.

301 with Chalder fatigue questionnaire score and physical functioning with short form-36 subscale score,

302 Average physical function worsened per 3 months on the waiting l