ライフサイエンスコーパス: phytochelatin

1 ut is coordinated tetrahedrally by sulfur of phytochelatin.

2 hat MT2 has a greater affinity for Zn2+ than phytochelatins.

3 it acts as a precursor for the synthesis of phytochelatins.

4 he three-enzyme pathway for the synthesis of phytochelatins.

5 the limited capacity of these plants to make phytochelatins.

6 nors are thus probably either glutathione or phytochelatins.

7 yces cerevisiae cells expressing PCS produce phytochelatins.

8 Phytochelatins, a class of posttranslationally synthesiz

9 n of all vacuolar ABC transporters abolishes phytochelatin accumulation in S. pombe vacuoles and abro

10 Abc2 expression restores phytochelatin accumulation into vacuoles and suppresses

11 y-metal tolerance and elicits Cd2+-activated phytochelatin accumulation when expressed in Saccharomyc

12 of the phytochelatins with heavy metals, the phytochelatin analogue peptides acetyl(gamma-glutamyl-cy

13 Lead is known to induce phytochelatins and antioxidative enzymes in vetiver; how

14 the accumulation of thiol compounds such as phytochelatins and glutathione, which are essential for

15 toxicity is thought to be mitigated through phytochelatins, and other toxic and nontoxic metals did

16 te plant response to Hg stress, glutathione, phytochelatins, and their Hg complexes were analyzed usi

17 The phytochelatins are a family of polydisperse, thiol-rich

18 Phytochelatins are thiol-rich peptides, whose production

19 l key genes that function in glutathione and phytochelatin biosynthesis in the WT, and this arsenic i

20 transporter for vacuolar sequestration of a phytochelatin/Cd complex, exhibited only mild hypersensi

21 suggesting that As may be stored as arsenite-phytochelatin complexes.

22 ases (phytochelatin synthases; EC 2.3.2.15), phytochelatins consist of repeating units of gamma-gluta

23 e data suggest that glutathione (and related phytochelatins) could act as key molecules for ensuring

24 owever, when MT deficiency was combined with phytochelatin deficiency, growth of the mt1a-2 mt2b-1 ca

25 ns, further supporting the essential role of phytochelatins for Pb detoxification.

26 thione biosynthesis, a process necessary for phytochelatin formation.

27 e synthesis of heavy-metal-binding peptides (phytochelatins) from glutathione and related thiols.

28 Moreover, MTs and phytochelatins function cooperatively to protect plants

29 The EC20sp synthetic phytochelatin gene was fused between the coding sequence

30 s of the cell surface display of a synthetic phytochelatin in the highly metal tolerant bacterium Cup

31 ant is unable to accumulate normal levels of phytochelatins in response to cadmium, although the cell

32 This study provides evidence for the role of phytochelatins in the detoxification of arsenate in arse

33 Involvement of phytochelatins in the detoxification of Pb(II) could be

34 d abc2 hmt1 double mutant show no detectable phytochelatins in vacuoles.

35 Cu-exposed cells, with the Cu ligand (e.g., phytochelatin) in P. tricornutum different from that in

36 r the generation of methionine, glutathione, phytochelatins, iron-sulfur clusters, vitamin cofactors,

37 en increased biosynthesis of glutathione and phytochelatins is required for detoxification purposes.

38 that the hmt1 mutant accumulates significant phytochelatin levels in vacuoles, suggesting that uniden

39 However, ars1 plants produce phytochelatin levels similar to levels produced by the w

40 Phytochelatins mediate tolerance to heavy metals in plan

41 Thus, although sulphide is required for phytochelatin-mediated metal tolerance, aberrantly high

42 als in plants and some fungi by sequestering phytochelatin-metal complexes into vacuoles.

43 Phytochelatins, once formed, are stable.

44 endodermis, suggesting enhanced synthesis of phytochelatins or glutathione.

45 iol-peptides synthesized as intermediates in phytochelatin (PC) biosynthesis confer cellular toleranc

46 proposed that SpHMT-1 transports heavy metal.phytochelatin (PC) complexes into the vacuolysosomal com

47 te rate-limiting factors for glutathione and phytochelatin (PC) production and the importance of thes

48 Phytochelatin (PC) synthase has been assumed to be a gam

49 Phytochelatin (PC) synthases are gamma-glutamylcysteine

50 monothioarsenate induced higher toxicity in phytochelatin (PC)-deficient mutants (cad1-3) as well as

51 Because phytochelatins (PC) protect plants from heavy metal toxi

52 The total content of phytochelatins (PCs) and their complexes are directly re

53 However, phytochelatins (PCs) are generally considered to functio

54 Phytochelatins (PCs) are glutathione-derived peptides th

55 Phytochelatins (PCs) are peptides that function in heavy

56 Phytochelatins (PCs) are post-translationally synthesize

57 class of heavy metal binding peptides termed phytochelatins (PCs) from GSH.

58 ments of the level of three major species of phytochelatins (PCs) in roots of plants exposed to Cd(2+

59 Phytochelatins (PCs), (gamma-Glu-Cys)n Gly polymers that

60 these, eight were identified as thiol-bound (phytochelatins [PCs], glutathione, and cysteine) species

61 esults indicate that GSH and the GSH-derived phytochelatin peptides do not play critical roles in det

62 The amino acid sequence of the phytochelatin peptides is (gamma-glutamyl-cysteinyl)n-gl

63 ces pombe detoxifies cadmium by synthesizing phytochelatins, peptides of the structure (gamma-GluCys)

64 d to Cu(I) and that polyphosphate bodies and phytochelatins play a significant role in the internaliz

65 Phytochelatins play major roles in metal detoxification

66 a 15-fold reduction in GSH level and lack of phytochelatin production was as tolerant as the wild-typ

67 ity phosphate uptake system and constitutive phytochelatin production.

68 NRs) of three aspect ratios were coated with phytochelatin-related peptides and studied using fluores

69 Synthetic phytochelatin-related peptides are used as an organic co

70 n in high yield, were covalently attached to phytochelatin-related peptides.

71 stosomes and roundworms, herald a new era in phytochelatin research, in which these novel post-transl

72 Directed evolution of Arabidopsis thaliana phytochelatin synthase (AtPCS1) yields mutants that conf

73 The dependence of phytochelatin synthase (gamma-glutamylcysteine dipeptidy

74 Enzymatic activity of phytochelatin synthase (PCS) in plant produces phytochel

75 n Arabidopsis thaliana AtPCS1 gene, encoding phytochelatin synthase (PCS), in Indian mustard (Brassic

76 ma-glutamyl-cysteine synthetase (gamma-ECS), phytochelatin synthase (PCS1) and phosphate effluxer (PH

77 binant purified S.pombe PCS protein displays phytochelatin synthase activity.

78 Although phytochelatin synthase improves the ability of Indian mu

79 Phytochelatin synthase is the enzyme responsible for the

80 b(II) could be demonstrated by investigating phytochelatin synthase mutants.

81 nse to cadmium, although the cells possess a phytochelatin synthase that is active in vitro.

82 These findings and others that demonstrate phytochelatin synthase-coding sequences in the genomes o

83 H-heavy metal adducts are the substrates for phytochelatin synthase.

84 eine synthetase, glutathione synthetase, and phytochelatin synthase.

85 tathione thiolate required as a substrate by phytochelatin synthase.

86 ro, AtPCS1 is concluded to encode the enzyme phytochelatin synthase.

87 Phytochelatin synthases (PCS) mediate cellular heavy-met

88 These data demonstrate that PCS genes encode phytochelatin synthases and mediate metal detoxification

89 However, genes encoding phytochelatin synthases have not yet been identified.

90 glutamylcysteine dipeptidyl transpeptidases (phytochelatin synthases; EC 2.3.2.15), phytochelatins co

91 ng increased GSH levels facilitate increased phytochelatin synthesis and sequestration of Cd, because

92 polypeptide for high rates of Cd2+-activated phytochelatin synthesis from glutathione in vitro, AtPCS

93 hat the precipitation of free cadmium blocks phytochelatin synthesis in vivo, by preventing upregulat

94 on of root growth and a lack of Pb-activated phytochelatin synthesis.

95 to the classical methods for purification of phytochelatins, this new method is more specific, simple

96 ze ABC transporter (ABCC-type) that mediates phytochelatin transport into vacuoles.

97 haromyces pombe Hmt1 has been described as a phytochelatin transporter and attempts to identify ortho

98 ls in vacuoles, suggesting that unidentified phytochelatin transporters exist in fungi.

99 and are proposed as the long-sought vacuolar phytochelatin transporters in plants and other organisms

100 sporter and attempts to identify orthologous phytochelatin transporters in plants and other organisms

101 o Cd2+ and Cu2+ and are unable to synthesize phytochelatins upon Cd2+ exposure as determined by HPLC

102 Elevated levels of phytochelatin were measured in plants with a range of to

103 e HPLC analyses show that elevated levels of phytochelatins were not detected in ars4, ars5 or ars4ar

104 ytochelatin synthase (PCS) in plant produces phytochelatins, which help in sequestration of heavy met

105 dicated that the arsenic-induced thiol was a phytochelatin with two subunits (PC(2)).

106 aracterize the coordination chemistry of the phytochelatins with heavy metals, the phytochelatin anal