ライフサイエンスコーパス: phytoestrogen

1 , we examined whether resveratrol might be a phytoestrogen.

2 rcuma comosa Roxb., has been identified as a phytoestrogen.

3 gency-sponsored quality assurance scheme for phytoestrogens.

4 in engineering plants to contain isoflavone phytoestrogens.

5 tofu), soy protein, or urinary excretion of phytoestrogens.

6 bone density may be favorably influenced by phytoestrogens.

7 s, including the naturally occurring dietary phytoestrogens.

8 e of the biological effects of diets rich in phytoestrogens.

9 ense properties, as well as similar roles as phytoestrogens.

10 , was investigated for 29 mycotoxins and two phytoestrogens.

11 ibitors belonging to the coumestan family of phytoestrogens.

12 phytoestrogens or on a chow nearly devoid of phytoestrogens.

13 s under the stimulation of estrogens but not phytoestrogens.

14 contained lower amounts of naturally present phytoestrogens.

15 wn to be a suitable method for hydrolysis of phytoestrogens.

16 ning diet [(P-600); that had 600 microg/g of phytoestrogens].

17 diets containing plant-derived isoflavones (phytoestrogens) afford protection against CVDs, suppleme

18 h, menopause, and climacteric, combined with phytoestrogens, alternative medicine, herbal medicine, t

19 t comprehensive suite of natural hormone and phytoestrogen analytes examined to date across a livesto

20 Resveratrol, a well-established phytoestrogen and chemopreventive agent, has gained much

21 We conclude that resveratrol is a phytoestrogen and that it exhibits variable degrees of e

22 T1A10 is important for detoxifying estrogens/phytoestrogens and aromatic acids with complementary act

23 Research on the relation between phytoestrogens and breast cancer risk has been limited i

24 Phytoestrogens and environmental xenoestrogens will fall

25 However, both phytoestrogens and estrogen inhibited RANKL-induced Ikap

26 attenuation of natural steroid hormones and phytoestrogens and estrogenic activity were assessed acr

27 s due to their biological activity as strong phytoestrogens and potent cancer chemopreventive agents.

28 Isoflavones are classified as both phytoestrogens and selective estrogen receptor modulator

29 nd to contain lower amounts of contaminating phytoestrogens and showed increased enzyme activity for

30 ethod has been developed for the analysis of phytoestrogens and their conjugates in human urine using

31 These phytoestrogens and their metabolites have many potent ho

32 ological evidence is needed on the levels of phytoestrogens and their metabolites in foods and biolog

33 ne and a variety of EDCs produced by plants (phytoestrogens), and that the diversity of organic EDCs

34 study, the distribution of steroid hormones, phytoestrogens, and estrogenic activity was thoroughly c

35 broad class of nonsteroidal estrogens called phytoestrogens, and in the past decade there has been co

36 Phytoestrogens appear to have little effect on breast ca

37 Phytoestrogens are a group of polyphenolic plant metabol

38 hough epidemiological data are inconclusive, phytoestrogens are considered to be beneficial for a var

39 Phytoestrogens are plant-derived compounds found mainly

40 though natural toxins, such as mycotoxins or phytoestrogens are widely studied and were recently iden

41 to that of cntnap2 mutants and show that the phytoestrogen biochanin A specifically reverses the muta

42 , these data present the first evidence that phytoestrogens can affect aggressive behavior and, concu

43 on to naturally occurring estrogens, dietary phytoestrogens can affect sexual differentiation.

44 emiological data suggest that consumption of phytoestrogens can be protective against the development

45 vironmental estrogen-like molecules, such as phytoestrogens, can also affect cardiac physiology in bo

46 In urine, all of the phytoestrogen conjugates hydrolyzed within 2h under stan

47 6 proved to be detrimental to hydrolysis of phytoestrogen conjugates, especially those in plasma.

48 The authors' findings suggest that dietary phytoestrogen consumption may partially defeminize adult

49 the beneficial and/or detrimental impacts of phytoestrogen consumption through commercial rodent diet

50 mals fed a phytoestrogen-free (P-free) vs. a phytoestrogen-containing diet [(P-600); that had 600 mic

51 mbined with an enzyme "blank" to correct for phytoestrogen contamination was shown to be a suitable m

52 The finding that variability in phytoestrogen content in commercial rodent diets, both w

53 or the general public, reliable data on the phytoestrogen content of food is necessary.

54 igher than the P-free values and the mbh-poa phytoestrogen content was 8-fold higher than the P-free

55 xposure duration and timing, dietary fat and phytoestrogen content, or lack of sophisticated phenotyp

56 nesis less effectively than the nonselective phytoestrogen daidzein, which effectively reproduced eff

57 initial experiments using estradiol and the phytoestrogens daidzein and genistein (compounds known t

58 Additionally, phytoestrogens decreased body weight but increased consu

59 on with females of both genotypes on the low phytoestrogen diet.

60 Exposure to these phytoestrogens early in life may have long-term health b

61 e cancer-preventative "mammalian" lignan or "phytoestrogen" enterolactone, formed in the gut followin

62 holesterol, fatty acids, vitamins, minerals, phytoestrogens, ethanol, and polyphenols, are either ben

63 rge range in both the amount and the type of phytoestrogens excreted.

64 idual variation seen in urinary isoflavonoid phytoestrogen excretion, we conducted a series of 3 huma

65 Early-life soy phytoestrogen exposure has been shown in Eker rats to in

66 support for persistent effects of early life phytoestrogen exposure on the uterus.

67 We hypothesized that phytoestrogen exposure regulates PTEN protein expression

68 he relation between uterine fibroid risk and phytoestrogen exposure.

69 tion between exposure to fungicides, dioxin, phytoestrogens, flame retardants, heavy metals and child

70 dietary xenobiotics including glycosides of phytoestrogens, flavonoids, simple phenolics and cyanoge

71 Genistein, a phytoestrogen found abundantly in soy products, is thoug

72 Resveratrol, a natural phytoestrogen found in red wine and a variety of plants,

73 ls (via Western analysis) from animals fed a phytoestrogen-free (P-free) vs. a phytoestrogen-containi

74 We used a phytoestrogen (PE) and a phytoestrogen-free (PE-Free) diet to determine whether o

75 either a phytoestrogen-rich (Phyto-600) or a phytoestrogen-free (Phyto-free) diet.

76 ales, which are nonagouti, were fed either a phytoestrogen-free control diet or one of six experiment

77 -6 weeks of age, transgenic males were fed a phytoestrogen-free diet (AIN-76A) containing 0, 100, 250

78 nts may provide the health benefits of these phytoestrogens from consumption of more widely used grai

79 wt(-1) x d(-1)), whereas the intake of these phytoestrogens from human milk is negligible (<0.01 mg/d

80 flammatory gene expression, because both the phytoestrogen genistein and low doses of EE were effecti

81 The phytoestrogen genistein is able to modulate uterine estr

82 with these findings, STX, tamoxifen, and the phytoestrogen genistein were able to increase SF-1 trans

83 either methyl donors like folic acid or the phytoestrogen genistein, negated the DNA hypomethylating

84 For example, dietary intake of phytoestrogen, genistein (Gen), seems to play a preventi

85 y study has been pursued on the nonsteroidal phytoestrogen, genistein.

86 The soy isoflavone phytoestrogens, genistein and daidzein, and equol (a dai

87 enis) was associated with maternal intake of phytoestrogens, given their potential impact on estrogen

88 diet) and soy protein from which most of the phytoestrogens had been extracted (low-isoflavone diet)

89 bDiet 5001) as compared to chow with minimal phytoestrogens (Harlan 2016 Teklad) was associated with

90 Phytoestrogens have a similar structure to estradiol and

91 Furthermore, phytoestrogens have antineoplastic effects with inhibiti

92 ared with soy protein from which most of the phytoestrogens have been extracted, soy protein with int

93 The phytoestrogens have certain similarities to 'designer ho

94 Phytoestrogens have the ability to bind estrogen recepto

95 ate intakes of soy protein containing intact phytoestrogens (high-isoflavone diet) and soy protein fr

96 ucibility and can be easily adapted to other phytoestrogens if required.

97 exposure to 17beta-estradiol or genistein (a phytoestrogen in soy protein-based diets), and neonatal

98 the first generic method for the analysis of phytoestrogens in food, using automated solid-phase extr

99 s of the metabolism and disposition of these phytoestrogens in humans.

100 large body of evidence documents the role of phytoestrogens in influencing hormone-dependent states.

101 amental plants) increase the distribution of phytoestrogens in surface waters.

102 In summary, phytoestrogens, in the form of dietary isoflavones, repr

103 fants fed soy formula receive high levels of phytoestrogens, in the form of soy isoflavones, during a

104 Broadly defined, phytoestrogens include isoflavones, coumestans, and lign

105 urine, and prostatic fluid concentrations of phytoestrogens, including genistein.

106 Phytoestrogens, including isoflavones and lignans, can a

107 have been extracted, soy protein with intact phytoestrogens increases HDL-cholesterol and apolipoprot

108 Excreta also contained phytoestrogens indicative of a soy-based diet, particula

109 The characterization of phytoestrogen intake and cancer risk has been hindered b

110 represents the first large-scale analysis of phytoestrogen intake and hypospadias.

111 sex/gender difference exists in response to phytoestrogen intake and what the possible underlying me

112 colorectal, and prostate cancers relative to phytoestrogen intake on the basis of a comprehensive dat

113 For example, the odds ratio for total phytoestrogen intake was 0.7 (95% confidence interval: 0

114 Phytoestrogen intake was not associated with breast canc

115 Phytoestrogen intake was not associated with breast canc

116 ontrols) cancers were calculated relative to phytoestrogen intake.

117 Individual phytoestrogen interventions such as dietary and suppleme

118 e P-free group, demonstrating the passage of phytoestrogens into brain.

119 terest in engineering the synthesis of these phytoestrogens into plants.

120 Phytoestrogen isoflavone intervention to engage the neur

121 Genistein is a phytoestrogen isoflavone that exerts agonist and antagon

122 From a panel of phytoestrogen isoflavones, biochanin A (BCA) was identif

123 Phytoestrogens (isoflavones and lignans) are of increasi

124 mized rats (9 weeks) on chow containing high phytoestrogen levels (Purina LabDiet 5001) as compared t

125 mice to a commercial rodent diet with higher phytoestrogen levels facilitates uterine growth in the p

126 plus maze and body weight were unaffected by phytoestrogen levels in the diet.

127 P-600 plasma phytoestrogen levels were 78-fold higher than the P-free

128 implantation compared with a diet with lower phytoestrogen levels.

129 significantly: (1) elevate plasma and brain phytoestrogens levels and (2) decrease brain calcium-bin

130 In the ArKO females raised on a diet high in phytoestrogens, lordosis was reduced in comparison with

131 Phytoestrogens may act as natural selective estrogen rec

132 Dietary phytoestrogens may contribute to the risk of colorectal

133 It may be logical to postulate that phytoestrogens may regulate proteins that control cellul

134 Genistein, a phytoestrogen, may have estrogenic cardioprotective acti

135 humans with a soy challenge, a comparison of phytoestrogen metabolism when subjects consumed fermente

136 In addition, dietary phytoestrogens modified mammary development and tumor la

137 Here, we identify Icaritin, a phytoestrogen molecule enhances self-renewal of mouse em

138 Liquiritigenin was found to be the principle phytoestrogen of the licorice extracts; however, it exhi

139 isolates and contain significant amounts of phytoestrogens of the isoflavone class.

140 This review is focused on the effects of phytoestrogens on cognition by examining clinical and an

141 needed to evaluate the long-term effects of phytoestrogens on obesity and diabetes mellitus and thei

142 s study characterized the effects of dietary phytoestrogens on the expression of body and prostate we

143 s study characterized the effects of dietary phytoestrogens on the expression of body weight, consumm

144 er on a standard mouse chow that was rich in phytoestrogens or on a chow nearly devoid of phytoestrog

145 e interactions between tamoxifen and dietary phytoestrogens (or isoflavones) by dose and form in vivo

146 uded plasticizers, phthalates, metals, PCBs, phytoestrogens, PAHs, heterocyclic amines, antioxidants,

147 ndicate that women ingesting high amounts of phytoestrogens, particularly as isoflavones in soy produ

148 doxically, high consumption of plant-derived phytoestrogens, particularly soybean isoflavones, is ass

149 We used a phytoestrogen (PE) and a phytoestrogen-free (PE-Free) di

150 Phytoestrogen [plant estrogenic-like molecule(s)] resear

151 Evidence is emerging that dietary phytoestrogens play a beneficial role in obesity and dia

152 nd cell culture systems suggest that dietary phytoestrogens play an important role in prevention of m

153 Natural phytoestrogen polyphenols, including resveratrol (RES),

154 Phytoestrogens present in soybeans and other plant produ

155 occurring estrogen-like molecules in plants (phytoestrogens), present via soy, in animal diets can al

156 occurring estrogen-like molecules in plants (phytoestrogens), present via soy, in animal diets, exert

157 Phytoestrogens produced anxiolytic effects in both male

158 r data provide evidence that a mechanism for phytoestrogens' protective nature is partially through i

159 ng naturally occurring amounts of isoflavone phytoestrogens reduced lipid peroxidation in vivo and in

160 imental protocols, animals were fed either a phytoestrogen-rich (Phyto-600) or a phytoestrogen-free (

161 Phytoestrogen-rich soy is known to ameliorate menopause-

162 However, little is known about phytoestrogen's effects on the CNS.

163 Black cohosh and foods that contain phytoestrogens show promise for the treatment of menopau

164 and Asian populations and clinical studies, phytoestrogens show promise to improve health and brain

165 ondary aim was to evaluate the effect of soy phytoestrogen (SPE) treatment on the severity of OA.

166 metabolite equol was by far the predominant phytoestrogen species, with daidzein, genistein, formono

167 Plant-derived phytoestrogens specifically have received much attention

168 Increased intake in phytoestrogens stemmed from the search for safe alternat

169 Concomitantly, phytoestrogen stimulation resulted in decreased Akt phos

170 Soy products, which contain phytoestrogens such as genistein, are one source of expo

171 or increased consumption of other sources of phytoestrogens such as whole grains, vegetables, fruits,

172 re slightly increased in cells stimulated by phytoestrogens, suggesting that the mechanism for increa

173 trials suggests that composite and specific phytoestrogen supplementations were associated with mode

174 cts of 2 popular, commercially available soy phytoestrogen supplements on anxiety in male, diestrus f

175 D3 is a weakly acting phytoestrogen that mimics the mitogenic responses produc

176 Taken together, BCA represents a natural phytoestrogen that mitigates stroke-induced injury by in

177 The isoflavones are a group of phytoestrogens that are present in high concentrations i

178 is a rich source of isoflavones--a class of phytoestrogens that has both antiestrogenic and anticarc

179 ds are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the

180 cts of endogenous T-derived E2 and exogenous phytoestrogens, the authors used an aromatase knockout (

181 re no dietary recommendations for individual phytoestrogens, there may be great benefit in increased

182 edlings can serve multiple purposes, e.g. as phytoestrogens they can provide health benefits and as n

183 Similar to broad conversion of phytoestrogens, UGT1A10 metabolized estrogens and their

184 Because phytoestrogen use in nutritional and pharmaceutical appl

185 hindered by the absence of accurate dietary phytoestrogen values.

186 These data suggest that consumption of phytoestrogens via a soy diet for a relatively short int

187 These data suggest that consumption of phytoestrogens via a soy diet, significantly: (1) decrea

188 Use of phytoestrogens was associated with a decrease in the num

189 Previously, food analysis for phytoestrogens was performed using either HPLC-UV or GC/

190 Daidzein, another phytoestrogen, was ineffective, but equimolar concentrat

191 nformation, we hypothesized that soy-derived phytoestrogens, weak estrogen-like substances in the soy

192 total isoflavones, total lignans, and total phytoestrogens were associated with reduced risks; odds

193 All of these phytoestrogens were found to be photolabile under certai

194 first time, average levels of all the above phytoestrogens were measured in samples of urine collect

195 Phytoestrogens were often more abundant than steroidal e

196 We report an assay for phytoestrogens which is sensitive, accurate, and uses lo

197 estrogen agonist is the plant-based group of phytoestrogens, which include isoflavones, lignans and c

198 ver sprouts can be considered as a source of phytoestrogens with high biological activity and as a di

199 s trace minerals and phenolic compounds, and phytoestrogens, with potential hormonal effects.