ライフサイエンスコーパス: pigment epithelium-derived factor

1 lar endothelial growth factor-A (VEGF-A) and pigment epithelium-derived factor.

2 Inhibitor, Clade F) gene which encodes PEDF (pigment epithelium-derived factor), a potent inhibitor o

3 antichymotrypsin), a neuroprotective factor (pigment epithelium-derived factor), an antiangiogenesis

4 high glucose while increasing the levels of pigment epithelium-derived factor, an endogenous inhibit

5 The bioactivity of signaling activated by pigment epithelium-derived factor and DHA uncovered syne

6 Two angiogenesis inhibitors, pigment epithelium-derived factor and tissue inhibitor o

7 three agents, combretastatin A-4 phosphate, pigment epithelium-derived factor, and angiopoietin-2.

8 Pigment epithelium-derived factor antibodies also were u

9 -angiogenic activity of thrombospondin-1 and pigment epithelium-derived factor both in vitro and in v

10 We found that the pigment epithelium-derived factor can promote long-term

11 at two such inhibitors, thrombospondin-1 and pigment epithelium-derived factor, derive specificity fo

12 elial growth factor while increasing that of pigment epithelium-derived factor in diabetic retinas.

13 lecules (such as angiostatin, endostatin, or pigment epithelium derived factor) in the cornea.

14 re, we show that neurotrophins, particularly pigment epithelium-derived factor, induce NPD1 synthesis

15 tor receptor-Erk1/2 signaling pathway by the pigment epithelium-derived factor is sufficient to maint

16 rly population doubling level cDNA-1/retinal pigmented epithelium-derived factor) is a single-copy, q

17 ted by 100 nm docosahexaenoic acid, 10 ng/ml pigment epithelium-derived factor, or NPD1.

18 Pigment Epithelium Derived Factor (PEDF) is a secreted f

19 ial growth factor (VEGF) and anti-angiogenic pigment epithelium derived factor (PEDF) may cause choro

20 lial growth factor (VEGF) and antiangiogenic pigment epithelium derived factor (PEDF) may cause choro

21 R), and VEGFR3 (FLT4); and the gene encoding pigment epithelium-derived factor (PEDF) (SERPINF1) was

22 te cyclase (GUC2D), beta-arrestin 2 (ARRB2), pigment epithelium-derived factor (PEDF) and recoverin (

23 rain-derived neurotrophic factor (BDNF), and pigment epithelium-derived factor (PEDF) and significant

24 Here, we identify the angiogenesis inhibitor pigment epithelium-derived factor (PEDF) as a key inhibi

25 We have reported previously that pigment epithelium-derived factor (PEDF) can, via gamma-

26 ransmembrane (IFITM)-like protein (BRIL) and pigment epithelium-derived factor (PEDF) defects cause t

27 The extracellular pigment epithelium-derived factor (PEDF) displays retina

28 ferative diabetic retinopathy, we found that pigment epithelium-derived factor (PEDF) effectively aba

29 ors tested the effect of adenoviral vectored pigment epithelium-derived factor (PEDF) gene transfer o

30 Pigment epithelium-derived factor (PEDF) has been identi

31 Pigment epithelium-derived factor (PEDF) has neuronal di

32 F) and up-regulates an angiogenic inhibitor, pigment epithelium-derived factor (PEDF) in a dose-depen

33 tudy, we tested the effect of treatment with pigment epithelium-derived factor (PEDF) in combination

34 The presence of pigment epithelium-derived factor (PEDF) in HAM was demo

35 duction of a secreted protein, expression of pigment epithelium-derived factor (PEDF) in mice harbori

36 er AAV-mediated intraocular gene transfer of pigment epithelium-derived factor (PEDF) inhibits the de

37 Pigment epithelium-derived factor (PEDF) is a 50-kD prot

38 Pigment epithelium-derived factor (PEDF) is a glycoprote

39 Pigment epithelium-derived factor (PEDF) is a member of

40 Pigment epithelium-derived factor (PEDF) is a multifunct

41 Pigment epithelium-derived factor (PEDF) is a multifunct

42 Pigment epithelium-derived factor (PEDF) is a potent ang

43 Pigment epithelium-derived factor (PEDF) is a potent ang

44 Pigment epithelium-derived factor (PEDF) is a potent inh

45 Pigment epithelium-derived factor (PEDF) is a serine pro

46 Pigment epithelium-derived factor (PEDF) is a serine pro

47 Pigment epithelium-derived factor (PEDF) is a serpin wit

48 Pigment epithelium-derived factor (PEDF) is an extracell

49 The cytokine pigment epithelium-derived factor (PEDF) is downregulate

50 Pigment epithelium-derived factor (PEDF) is important fo

51 Pigment epithelium-derived factor (PEDF) is known to be

52 ELISA was performed to measure pigment epithelium-derived factor (PEDF) levels from con

53 a1 transcription factor and are dependent on pigment epithelium-derived factor (PEDF) on the outer su

54 ral (rAAV) serotype-2-mediated expression of pigment epithelium-derived factor (PEDF) or Kringle doma

55 ation of the known neuroprotective molecule, pigment epithelium-derived factor (PEDF) plus docosahexa

56 Pigment epithelium-derived factor (PEDF) protects immatu

57 ascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) protein, and mR

58 The cytoprotective effects of pigment epithelium-derived factor (PEDF) require interac

59 vIII induces the expression and secretion of pigment epithelium-derived factor (PEDF) via activation

60 Pigment epithelium-derived factor (PEDF) was increased m

61 eptors (VEGFR-1, VEGFR-2, Npn-1, Npn-2), and pigment epithelium-derived factor (PEDF) were also exami

62 asminogen activator inhibitor-1 (PAI-1), and pigment epithelium-derived factor (PEDF) were measured b

63 Pigment epithelium-derived factor (PEDF), a member of th

64 identify proteolytic activities that cleave pigment epithelium-derived factor (PEDF), a member of th

65 tified a novel inhibitor of the Wnt pathway, pigment epithelium-derived factor (PEDF), a multifunctio

66 Pigment epithelium-derived factor (PEDF), a neurotrophic

67 Pigment epithelium-derived factor (PEDF), a neurotrophic

68 Pigment epithelium-derived factor (PEDF), a noninhibitor

69 f these ocular compartments is identified as pigment epithelium-derived factor (PEDF), a protein prev

70 Pigment epithelium-derived factor (PEDF), a protein secr

71 Furthermore, pigment epithelium-derived factor (PEDF), a secreted gly

72 n difference, we have measured the levels of pigment epithelium-derived factor (PEDF), an angiogenic

73 ociated transcription factor (MITF) acts via pigment epithelium-derived factor (PEDF), an antiangioge

74 The neurotrophic activity of pigment epithelium-derived factor (PEDF), an extracellul

75 ng endostatin, thrombospondin-1 (TSP-1), and pigment epithelium-derived factor (PEDF), as well as by

76 One of these molecules, pigment epithelium-derived factor (PEDF), is a broadly e

77 Pigment epithelium-derived factor (PEDF), the protein pr

78 Null mutations in for pigment epithelium-derived factor (PEDF), the protein pr

79 or 26 weeks, was analyzed by immunoassay for pigment epithelium-derived factor (PEDF), vascular endot

80 scular endothelial growth factor (VEGF), and pigment epithelium-derived factor (PEDF).

81 ations of hepatocyte growth factor (HGF) and pigment epithelium-derived factor (PEDF).

82 ion (CNV) and regulation of MMP-2 and -9 and pigment epithelium-derived factor (PEDF).

83 lial growth factor (VEGF) and antagonized by pigment epithelium-derived factor (PEDF).

84 Loss of pigment epithelium-derived factor (PEDF, SERPINF1) in ca

85 The net secretion of pigment-epithelium-derived factor (PEDF) was directed ap

86 corneas were harvested for ELISA (VEGFR3 and pigment epithelium-derived factor [PEDF]) and for quanti

87 l, revealed that they constitutively secrete pigment epithelium-derived factor, PEDF, which is known

88 ults further indicate that activation of the pigment epithelium-derived factor receptor-Erk1/2 signal

89 Pigment epithelium-derived factor restoration increases

90 ing alpha-1 microglobulin/bikunin precursor, pigment epithelium-derived factor, surfactant protein B,

91 Also, DHA and pigment epithelium-derived factor synergistically modify

92 th increased levels of type III collagen and pigment epithelium-derived factor, which accumulate in t