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1 that are significantly associated with skin pigmentation.
2 enerate mature melanocytes for hair and skin pigmentation.
3 hite allele causes a nearly complete loss of pigmentation.
4 nd simultaneous development of lopsided body pigmentation.
5 ignaling cascade at multiple levels restored pigmentation.
6 nosomal membrane potential, pH, and regulate pigmentation.
7 and new aspects of hair follicle biology and pigmentation.
8 cesses including vision, olfaction, and skin pigmentation.
9 eptor, has a crucial role in human and mouse pigmentation.
10 melanosome degradation, is also critical for pigmentation.
11 ng different viable mutations affecting skin pigmentation.
12 ediated upregulation of Kitl influences skin pigmentation.
13 h (Raphanus sativus L.) by intermolecular co-pigmentation.
14 responsible for an EBS subtype with mottled pigmentation.
15 unction and signaling mediated by carotenoid pigmentation.
16 sity, especially with respect to patterns of pigmentation.
17 primary melanomas scored for histopathologic pigmentation.
18 lities, and occasional or late-onset retinal pigmentation.
19 cted cellular cytotoxicity without affecting pigmentation.
20 d tested for associations with skin and hair pigmentation.
21 mentation did not significantly affect juice pigmentation.
22 complement to the traditional colorant-based pigmentation.
23 bleb, and focal scleromalacia with localized pigmentation.
24 tes and defined how these cells reconstitute pigmentation.
25 clock processes in the regulation of melanin pigmentation.
26 fuscin in renal tubules that account for the pigmentation.
27 enes affecting eyespot development and black pigmentation.
28 d thereby promote cargo delivery and optimal pigmentation.
29 ); of these, 13 tumors (26%) showed variable pigmentation.
30 nvolvement, extrascleral extension, or tumor pigmentation.
31 ion in vitro more than melanocytes with high pigmentation.
32 eripheral clock activity influences human HF pigmentation.
33 component of the MBW activation complex for pigmentation.
34 shape of the skeleton as well as defects in pigmentation.
35 tic subterranean habitats have lost all body pigmentation.
36 e of differentiated melanocytes and for hair pigmentation.
37 zes the chemistry and role of astaxanthin in pigmentation.
38 had prior primary melanomas also scored for pigmentation.
39 light responses are linked to phylogeny and pigmentation.
40 tions to discover new genes influencing skin pigmentation.
41 of this analog still led to significant skin pigmentation.
42 e identified an R2R3-MYB, Reduced Carotenoid Pigmentation 1 (RCP1), as the first transcription factor
43 uration (3%, 4%, 7%, 11%) (P < 0.001), tumor pigmentation (48%, 53%, 69%, 78%) (P < 0.001), and extra
44 patients with incident melanomas scored for pigmentation, 527 had prior primary melanomas also score
45 iated with KITLG, previously associated with pigmentation abnormalities, and will thereby improve the
46 h cAMP and protein kinase A (PKA), regulates pigmentation, adaptive tanning, and melanoma resistance.
47 own to be involved in feather development or pigmentation: agouti signaling protein (ASIP), follistat
49 rial mutant casper, the crystal mutant lacks pigmentation also in the retinal pigment epithelium, the
50 E dedifferentiation was indicated by reduced pigmentation, altered cellular morphology and a reductio
51 ight is required for Vitamin D synthesis and pigmentation, although it is plausible that longer visib
52 longed sun exposure as surrogate measures of pigmentation among 49,323 white women in the Nurses' Hea
53 nfirm the association of rs1426654 with skin pigmentation among South Asians, consistent with previou
55 om common melanocytic nevi by variegation in pigmentation and clinical appearance, as well as differe
56 nd significant correlation between increased pigmentation and complex II turnover was observed in gen
57 es two morphs, tan and white, that differ in pigmentation and components of social behavior [3-5].
60 t it is essential for multicellular conidial pigmentation and development in a plant endophytic fungu
61 on CM or CM-related host phenotypes (such as pigmentation and eye color) and tested them for associat
63 e speciation but the genetic basis of animal pigmentation and how colour polymorphisms contribute to
64 sequencing in patients with FHL with normal pigmentation and identify a critical binding site for Mu
65 tect selection at loci associated with diet, pigmentation and immunity, and two independent episodes
66 ates as a cell-autonomous modulator of human pigmentation and may be targeted for future therapeutic
69 ck to the P. fici DeltaPfmaE mutant restored pigmentation and multicellular adherence of the conidia.
71 anum lycopersicum) mutants affected in fruit pigmentation and nutritional content can provide valuabl
73 mentation of SSB01 cultures causes a loss of pigmentation and photosynthetic activity, disorganizatio
76 Resulting mice exhibit abnormalities in skin pigmentation and reproductive tissue architecture, and a
77 les (MAC) are the most frequent cause of lip pigmentation and sometimes difficult to differentiate fr
78 ed with LM or LMM: (1) asymmetric follicular pigmentation and targetlike structures, and (2) round, l
79 th the genetic architecture of avian feather pigmentation and the evolutionary history and conservati
80 ntified that are involved in regulating skin pigmentation and these act during development, survival,
81 t that PDK1 contributes functionally to skin pigmentation and to the development of melanomas harbori
82 skin xanthophores, which mediate red/yellow pigmentation and trafficking, but not in tissues associa
84 acid is critical in establishing asymmetric pigmentation and, via cross-talk with thyroid hormones,
85 aureus that display small colonies, reduced pigmentation, and decreased hemolysis and/or coagulase a
86 intrinsic tumor vascularity, increased tumor pigmentation, and decreased tumor thickness with synchro
87 ed with benign tumours, spotty mucocutaneous pigmentation, and endocrine overactivity (Ophthalmic Sur
90 , Cdc42 null mice displayed a severe loss of pigmentation, and melanoblasts showed cell-cycle progres
91 ownregulates betalain biosynthetic genes and pigmentation, and overexpressing BvMYB1 upregulates them
92 roplast replication, fatty acid composition, pigmentation, and photosynthetic parameters were charact
94 tinctive, genetically programmed patterns of pigmentation, and the recessive k1 mutation can epistati
97 ve alleles--especially those associated with pigmentation--are mostly of hunter-gatherer origin, alth
99 ticipate in the patterning of the carapacial pigmentation as both the migratory neural crest cells an
100 ukoplakia, nail dystrophy, and abnormal skin pigmentation, as well as high rates of bone marrow (BM)
101 D) is an autosomal-dominant disorder of skin pigmentation associated with mutations in keratin 5 (KRT
102 determine temporal and spatial patterning of pigmentation at the cellular level, especially for PAs.
103 ffers many benefits compared to conventional pigmentation based display technologies, such as increas
105 tial pattern variation of floral anthocyanin pigmentation between two sister species of monkeyflower:
108 between self-reported hearing loss and skin pigmentation by using hair color, skin tanning ability,
110 ations, we show how the architecture of skin pigmentation can vary across humans subject to different
111 AF mutation into that of DPN, with increased pigmentation, cell volume and nuclear cyclin D1 levels.
112 d downregulation of Hsp70-1A correlated with pigmentation changes in cultured melanocytes, modified h
113 ion study for variants associated with human pigmentation characteristics two coding variants of TPC2
114 dynamic and responsive relationship between pigmentation, complex II function, and intracellular sup
115 atients had patches of increasing subretinal pigmentation consistent with transplanted retinal pigmen
119 ring the pathological mechanisms involved in pigmentation diseases, and provide a robust assay for th
120 or studies of melanocyte lineage commitment, pigmentation disorders and cell replacement therapies.
121 afe and effective treatment options for skin pigmentation disorders are limited, these specific GPER
124 s were identified as containing colorimetric pigmentation due to residual matrix from the specimen or
126 complications) and minor adverse events (eg, pigmentation, edema, telangiectatic matting, and hematom
127 nins (>six galloyl units) exerted smaller co-pigmentation effects (36+/-2%; Deltalambdamax 13nm), pos
128 -glucose induced greatest and most stable co-pigmentation effects (53+/-2%; Deltalambdamax 13nm).
131 covariation of UV-B irradiance and UV floral pigmentation from within species to that among species,
132 N. vitripennis, we targeted a conserved eye pigmentation gene cinnabar, generating several independe
133 conidial pigmentation mutants, a new fungal pigmentation gene cluster, which contains Mr-Pks1, Mr-Et
135 show that a missense mutation in a classical pigmentation gene, melanocyte stimulating hormone recept
136 tion associated with decreased expression of pigmentation genes and increased expression of cytokines
137 ation regulatory pathway, and that all three pigmentation genes exercise feedback regulation of conid
139 the association of two previously known skin pigmentation genes, SLC24A5 (minimum p = 2.62 x 10(-14),
142 tion between pregnancy and altered cutaneous pigmentation has been documented for over two millennia,
144 Our understanding of the genetics of skin pigmentation has been largely skewed towards populations
145 a in anthocyanic taxa suggests that betalain pigmentation has been lost twice in Caryophyllales, and
149 and contributed to the evolution of betalain pigmentation, highlighting the significance of upstream
150 margins without clinically apparent residual pigmentation; however, more data are needed to make defi
151 case activities and showed defects in colony pigmentation, hyphal surface hydrophobicity, cell wall i
154 patterns of variation in UV-absorbing floral pigmentation in a widespread plant, Argentina anserina (
155 ll other loci, variants associated with dark pigmentation in Africans are identical by descent in Sou
156 results introduce an unprecedented source of pigmentation in amphibians and highlight the potential r
161 nly impacts our fundamental understanding of pigmentation in extant organisms but also provides a sig
162 xpression in tobacco resulted in the loss of pigmentation in flowers due a decrease in anthocyanin ac
163 Here we present direct chemical evidence of pigmentation in fossilized skin, from three distantly re
166 ion mutations in the NFU3 gene caused yellow pigmentation in leaves, reductions in plant size, leaf s
167 roles in cell elongation, lignification and pigmentation in plants and could play crucial role in co
169 asis of evolutionary changes in male-limited pigmentation in several pairs of Drosophila species that
174 ologs arose during the evolution of betalain pigmentation in the core Caryophyllales and later experi
176 40 and one bHLH gene controlling anthocyanin pigmentation in the entire corolla of M. lewisii and two
178 Although the contribution of human cells to pigmentation in the host was lower than that of mouse or
183 This post-treatment increase in cellular pigmentation induced a significant increase in PAI signa
186 nd confirmed previous findings, showing that pigmentation is a critical determinant of skin aging.
187 Finally, we determined that the degree of pigmentation is a key feature defining cells with metast
189 chanisms to ensure the degree of anthocyanin pigmentation is appropriate to myriad developmental and
190 To test whether clofazimine-induced skin pigmentation is due to CLDI formation, we synthesized a
193 pigmentation phenotypes, we demonstrate that pigmentation is more complex than previously assumed, wi
194 esults suggest that clofazimine-induced skin pigmentation is not due to clofazimine precipitation and
199 tion using the perceived biological basis of pigmentation leads to enhanced genetic association and p
200 nor adverse event, with a 3.53% treated-vein pigmentation length for group 1 and 7.09% for group 2, w
201 droxyapatite crystallites) associated with a pigmentation line in dentine and with a distinct neonata
202 pigmentation is highly heritable, but known pigmentation loci explain only a small fraction of the v
203 we identify canonical and non-canonical skin pigmentation loci, including near SLC24A5, TYRP1, SMARCA
205 e Bayesian LMMs provide evidence for two new pigmentation loci: one for eye color (AHRR) and one for
206 of the 129 mouse background are resistant to pigmentation locus-negative (pgm(-)) Yersinia pestis and
207 histologic margins without clinical residual pigmentation may be safely observed rather than reexcise
208 th FHL with immunodeficiency but with normal pigmentation might sometimes have mutations that affecte
209 that the activity of the master regulator of pigmentation, MITF, and its downstream targets may be re
214 ; 18%), nonpigmented (n = 2; 12%), and mixed pigmentation (n = 12; 71%), and with no surrounding halo
215 ering from the classic spicular intraretinal pigmentation observed in other individuals homozygous fo
217 Gloger's rule and its corollaries state that pigmentation of endothermic animals will increase from m
222 s spectroscopic analyses and observe lighter pigmentation of the large parascapular spines, consisten
224 nd development of remarkable diffuse mottled pigmentation on the trunk and proximal extremities.
225 lliform surface (OR, 2.1 [95% CI, 1.3-3.5]), pigmentation (OR, 1.5 [95% CI, 1.0-2.2]), temporal locat
226 implicated in the evolution of sex-specific pigmentation outside the montium subgroup, suggesting th
228 ix progenitors that regulate hair growth and pigmentation, partly by creating an SCF-dependent niche
230 hree key genes known to be involved in human pigmentation pathways--HERC2, SLC45A2, and TYR--using al
231 eviously unidentified allele for the gloving pigmentation pattern found in the Birman breed supports
233 ators, suggesting that it probably regulates pigmentation patterning by regulating scale cell develop
234 se three PeMYBs participated in the distinct pigmentation patterning in a single flower, which was re
238 r long-lasting flowers of various colors and pigmentation patterning, Phalaenopsis spp. have become i
240 any vertebrate species visible melanin-based pigmentation patterns correlate with high stress- and di
241 aries strongly with light environment [7-9], pigmentation patterns give clues to an animal's habitat.
244 gh UVR environments is expected to constrain pigmentation phenotype and variation in pigmentation loc
245 gene mutation(s) accountable for the mottled pigmentation phenotype in a patient with suspected inher
246 he first clinically well-documented, mottled pigmentation phenotype related to a novel EXPH5 mutation
247 script isoforms expressed exclusively in one pigmentation phenotype, 17 of which are genes involved i
249 embling a global survey of quantitative skin pigmentation phenotypes, we demonstrate that pigmentatio
250 mphasize the complex genetic architecture of pigmentation phenotypes, which are controlled by multipl
254 PeMYB12 resulted in the loss of the full-red pigmentation, red spots, and venation patterns, respecti
255 10(-8)) including seven previously confirmed pigmentation-related loci: MC1R, ASIP, TYR, SLC45A2, OCA
260 Genes that encode functions related to skin pigmentation (SCL4A5) and cutaneous glands (EDAR) are al
261 ect ORs were adjusted for age, smoking, iris pigmentation, self-reported cardiovascular disease, self
263 Intraepithelial nonproliferative melanocytic pigmentation signifies the usually small number of conju
264 ptibility to UV radiation (UVR)-induced skin pigmentation, skin cancers, ocular surface disease, and,
265 cially PsbF, lower PSII activity, pale green pigmentation, smaller leaf and plant sizes, and retarded
267 reover, mouse and human melanocytes with low pigmentation stimulate endothelial cell (EC) proliferati
273 luding spectral tuning, oil droplet size and pigmentation, synaptic targets, and spatial patterning,
274 compounds, including polymeric pigments, co-pigmentation, tannins and iron-reactive polyphenols.
276 score (P = 0.0009), and improvements in scar pigmentation, thickness, surface roughness, and mechanic
277 ession of either TSC1 or TSC2 causes reduced pigmentation through mTORC1 activation, which results in
278 Thus, our data show that TPC2 regulates pigmentation through two fundamental determinants of mel
279 nce that the genetic factors associated with pigmentation traits are risk loci of UM susceptibility.
280 proportions proposed to represent differing pigmentation types, such as pheomelanin, eumelanin, and
281 ng MC1R signalling, which triggers increased pigmentation, ultraviolet-B-induced G1-like cell cycle a
282 Genetic evidence indicates that the light pigmentation variant at SLC24A5 was introduced into East
284 enes have been directly associated with skin pigmentation variation in humans, leading to its charact
285 mparative approaches to determine whether UV pigmentation variation is associated with geography and/
293 ations in the characterization of human iris pigmentation, we introduce a fully automated approach th
294 r cohort of white women, surrogates for skin pigmentation were not associated with risk of hearing lo
295 teristics, receipt of vasopressors, and skin pigmentation were recorded at the time of a clinical art
296 and qualitative effects of intermolecular co-pigmentation were studied by adding chlorogenic and rosm
300 a result of cell type and not differences in pigmentation, yolk content, cell size, or position in th
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