ライフサイエンスコーパス: pill

1 ables", "progestin", and "oral contraceptive pills".

2 inactive negative ion generator plus placebo pill).

3 A ninth group received CBI only (no pills).

4 the forces experienced by an orally ingested pill.

5 xyprogesterone acetate, 2.5 mg/d, or placebo pill.

6 000/QALY and statins cost $1.54 to $2.21 per pill.

7 ALY) if low-intensity statins cost $2.11 per pill.

8 tory, or prior use of the oral contraceptive pill.

9 was compared to that of women not taking the pill.

10 tive regimens now available as a one per day pill.

11 ngs, ease, and convenience of a daily-dosing pill.

12 rily and increasingly limited by the size of pills.

13 lso reported findings for oral contraceptive pills.

14 acebo (n = 20): FMUD associated with placebo pills.

15 fe, effective method for localizing magnetic pills.

16 binations of DAAs and fixed-dose combination pills.

17 ely to prefer an annual infusion over weekly pills.

18 an access, afford, and tolerate taking daily pills.

19 was in the range between 5.5 and 49microg in pills.

20 emained for women compliant with their study pills (0.92 [0.76-1.10]; P = 0.36).

21 of an active component of the birth control pill (17alpha-ethynylestradiol; EE2) that resulted in th

22 r 30 min/d in the early morning plus placebo pill); (2) antidepressant monotherapy (inactive negative

23 I, 1.75-1.84) and those using progestin-only pills, 2.2 (95% CI, 1.99-2.52).

24 69% [P = .18]; patch, 50% to 71% [P = .002]; pills, 41% to 65% [P < .001]; condoms, 25% to 45% [P = .

25 More respondents chose FMT if offered as a pill (90%; P = .002) or if their physician recommended i

26 ys of order-balanced varenicline and placebo pill administration and were scanned under each conditio

27 oximately 17 days of varenicline and placebo pill administration and were scanned, on different days

28 R], 0.6; 95% CI, .4-1.2), oral contraceptive pill (aHR, 0.8; 95% CI, .3-2.1), nor implant (aHR, 0.8;

29 This is the first report of a single-pill, all-oral, interferon-free, ribavirin-free treatmen

30 ld also be combined into a single fixed-dose pill, along with pyridoxine (vitamin B6), that would be

31 virenz in the United States, a once-daily, 3-pill alternative (generic efavirenz, generic lamivudine,

32 egulate attractive forces between a magnetic pill and an external magnet, while visualizing internal

33 n assumptions were less favorable ($1.00 per pill and disutility=0.00384), CAC screening with statin

34 red the most important attribute and a daily pill and longer lasting injection in the arm were the pr

35 statin assumptions were favorable ($0.13 per pill and no quality of life penalty).

36 rent effects of genuine acupuncture, placebo pill and rest control on pain threshold.

37 een introduced in the market both in vitamin pills and in fortified foods.

38 Placebo pills and meeting with a health care professional had a

39 and 262 women randomized to receive placebo pills and patches.

40 atients and non-infected teens who crush the pills and smoke the powder for its psychoactive effects.

41 s (n=11) after oral ingestion of antioxidant pills and were irradiated (10 mGy).

42 met to legitimately use the terms 'exercise pill' and 'exercise mimetic' are presented.

43 o filled an opioid prescription had leftover pills, and 26 of the 49 patients (53%) planned to keep t

44 x, race, numeracy, difficulty with obtaining pills, and number of pills taken per day but did not var

45 mood-altering drugs (tranquilizers, sleeping pills, and stimulants).

46 n in the control group received multivitamin pills, and the intervention group received vitamins and

47 variants of an innovator drug have the same pill appearance to reduce errors and promote drug adhere

48 In many cases excess pills are prescribed.

49 um forces and torques experienced in vivo by pills as a quantitative measure of the amount of force p

50 d, the challenge from others of an 'exercise pill' as a mimetic of natural physical activity will be

51 olesterol-lowering medications into a single pill associated with improved cardiovascular disease (CV

52 nt of subjects were taking the contraceptive pill at the time of periodontal examination.

53 'polypill strategy' refers to making such a pill available to the population based on age (e.g. 55 y

54 otential oral administration of any magnetic pill-based delivery system.

55 e replacement therapy (HRT) or birth control pills (BCPs) influence risk for age-related macular dege

56 to 1 of 4 parallel groups: no pills, placebo pills (blinded), echinacea pills (blinded), or echinacea

57 no pills, placebo pills (blinded), echinacea pills (blinded), or echinacea pills (unblinded, open-lab

58 ill devices that transmit data each time the pill bottle is opened.

59 ounced home-based pill counts and electronic pill bottle monitoring.

60 participants' capecitabine bottles to record pill bottle openings.

61 hypertensive medication identified through a pill bottle review.

62 er flea), Cladocera (brine shrimp), Isopoda (pill bugs), Amphipoda (scuds, sideswimmers), and Decapod

63 s (HCV) genotype 1, the regimens have a high pill burden and are associated with increased rates and

64 enefit from regimen simplification to reduce pill burden and dosing frequency.

65 Simplified regimens with reduced pill burden and fewer side-effects are desirable for peo

66 ens are simpler than in the past, with lower pill burden and once-daily dosing frequency common.

67 d trials (RCTs) to investigate the impact of pill burden and once-daily vs twice-daily dosing on ART

68 pends more on the disutility associated with pill burden than their degree of cardiovascular risk.

69 Lower pill burden was associated with both better adherence an

70 Higher pill burden was associated with both lower adherence rat

71 e disutility caused by daily medication use (pill burden).

72 ults with consideration of dosing frequency, pill burden, adverse toxic effect profiles, comorbiditie

73 emental toxic effects, high costs, increased pill burden, and many drug interactions.

74 Omitting NRTIs will reduce pill burden, cost, and toxicity in this patient populati

75 tease inhibitor-containing regimens, greater pill burden, higher maximum number of doses per day, and

76 it generally effective, are hampered by high pill burden, long duration of treatment, coexistent toxi

77 ptase inhibitor (NRTI)-sparing benefits, low pill burden, once-daily dosage, and safety.

78 ir alone is a possible option because of low pill burden, once-daily dosing, safety, and unique resis

79 reduced dosages was associated with reduced pill burden, reduced treatment costs, and a trend toward

80 Fixed-dose combinations could reduce pill burdens and costs as well as improving patient adhe

81 A) and, perhaps, low-dose oral contraceptive pills can have adverse effects on adolescent bone health

82 The proposed method (PILL) can serve as a valuable tool for protein function

83 (4 month assessment) assessed via electronic pill caps (Medication Event Monitoring System [MEMS]) wi

84 eligible for TIPS, Poly-Iran, Wald, and the PILL Collaboration, CAC = 0 was observed in 58.6%, 54.5%

85 patients increased by 34% after a change in pill color (adjusted odds ratio, 1.34 [95% CI, 1.12 to 1

86 Rates of changes in pill color and shape during the year after MI were calcu

87 sistence were evaluated to determine whether pill color or shape had changed.

88 The term 'polypill' denotes a single-pill combination of drugs for reducing cardiovascular di

89 s for blood pressure measurement, and single-pill combination pharmacotherapy.

90 more, our model predicts that certain single-pill combination therapies can prevent resistance regard

91 In comparison with monotherapy, single-pill combinations and multiple-pill combinations were as

92 ady been randomised to treatment with single-pill combinations of either benazepril and hydrochloroth

93 erapy, single-pill combinations and multiple-pill combinations were associated with 55% and 26% incre

94 item-respondents could select birth control pills; condoms; an intrauterine device or implant; injec

95 bo-controlled trial to receive a combination pill containing folic acid, vitamin B6, and vitamin B12

96 vs 35%; p=0.001) and have adherence <90% by pill count (42 vs. 0%; p=0.02).

97 nding the final visit with MAQ = 20 and high pill count (80% to 110%) combined, to assess adherence.

98 ported Morisky-Green questionnaire (MAQ) and pill count (patients had to meet both criteria for adher

99 We analysed factors associated with pill count adherence (PCA) of less than 95%, medication

100 y; counseling was intensified if unannounced pill count adherence fell to <80%.

101 was 98.6% (standard deviation [SD], 2.4) by pill count and 98.5% (SD, 2.7) by self-report; 86% repor

102 east 20% of doses were missed as measured by pill count and failure to open the medication monitor bo

103 ug, adherence counselling and measurement by pill count and self-reporting, and risk reduction counse

104 gh adherence to the study medication (92% by pill count).

105 ion adherence was 97% by self-report, 96% by pill count, and 84% by urine monitoring.

106 doses missed or not ingested with a meal, by pill count, and by plasma concentrations of tenofovir an

107 Among women with complete pill counts (97% adherence), the mean decrease in CRP wa

108 rtile range [IQR] 96.9%-100%) by unannounced pill counts and 97.2% (90.6%-100%) by electronic monitor

109 PrEP adherence using unannounced home-based pill counts and electronic pill bottle monitoring.

110 However, while pill counts and self-reports indicated that more than 66

111 nd measured using clinical documentation and pill counts for direct observation, and self-reports, pi

112 Subjects made monthly visits, at which time pill counts were made and fasting blood samples were col

113 ts for direct observation, and self-reports, pill counts, and medication event-monitoring devices for

114 was measured in 55 patients using the MASRI, pill counts, and physician ratings (MD scale).

115 nts, performing urine drug tests, monitoring pill counts, and reviewing prescription drug monitoring

116 etrics of drug adherence (e.g., self-report, pill counts, blood monitoring) have limitations, and ana

117 , 1.77-2.15]) than were doses less than 0.75 pills/d (OR, 1.63 [95% CI, 1.48-1.78]; P = .007 for inte

118 Doses more than 1.5 PPI pills/d were more strongly associated with vitamin B12 d

119 er for higher daily doses (>1.5 vs <0.75 PPI pills/d; P value interaction = .004) and decreased after

120 Mean utility for taking a pill daily for cardiovascular prevention is approximatel

121 ensitive to patient preferences for taking a pill daily, changes to statin price, and the risk of sta

122 s in the disutility associated with taking a pill daily, statin price, and the risk of statin-induced

123 to pay an average of $1445 to avoid taking a pill daily, which translated to a mean utility of 0.994

124 se risk factors if they do not mind taking a pill daily.

125 amount of time to avoid taking a preventive pill daily.

126 eas over 90% of participants reported taking pills daily while on early ART.

127 ess than a college degree; and 79% took >/=1 pills daily.

128 t UTI prevention compared to daily cranberry pills, daily estrogen therapy, and acupuncture.

129 lls/day: OR, 1.41 [95% CI, 1.21-1.64]; <0.74 pills/day: OR, 1.12 [95% CI, 0.94-1.33]).

130 ssociated with increased risk (eg, > or =1.5 pills/day: OR, 1.41 [95% CI, 1.21-1.64]; <0.74 pills/day

131 Prescription utilization (measured in pill-days) and out-of-pocket expenditures, as determined

132 cts received one of four treatments: placebo pills (described as Tylenol), sham acupuncture, genuine

133 gastric contractility that will aid rational pill design and provide a quantitative framework for int

134 to the intervention group counted patients' pills, designated a family member to support adherence b

135 y after both groups stopped taking the study pills, despite a similar frequency of mammography.

136 Consumption of protein powder and isoflavone pills did not differ between groups, and compliance with

137 e their medications (70.6%); and that taking pills did not interfere with their daily activities (85.

138 with either bupropion or a matching placebo pill (double-blind).

139 of varenicline (0.5 mg) or matching placebo pill (double-blind, random order) before imaging.

140 son of ever to never or rare users (< or =30 pills during observation period), no evidence was observ

141 t guidelines recommend branded once-daily, 1-pill efavirenz-emtricitabine-tenofovir as first-line ant

142 PILL estimates the missing labels for a protein based on

143 that little disutility results from taking a pill every day.

144 The concept of an 'exercise pill'/'exercise mimetic' demonstrates an inadequate appr

145 quantitative measure of the amount of force pills experience during the muscular contractions leadin

146 The fraction of time pills experience ranges of forces and torques are analyz

147 The decrease in utility attributed to taking pills for cardiovascular prevention can have major effec

148 igh adherence as self-report of taking "all" pills for each prescribed ART medication; all other repo

149 placebo and smaller nocebo effects than did pills for the treatment of hot flashes.

150 y to effectively transfer food, liquids, and pills from their mouth to stomach.

151 and 1 cell/high-power field [hpf] in the no-pill group, 39 ng/L and 1 cell/hpf in the blinded placeb

152 he blinded placebo group; and 286 for the no-pill group.

153 linded placebo group and 7.03 days in the no-pill group.

154 The pill groups had more treatment-related adverse events th

155 Users of progestogen-only pills had an RR for first use of an antidepressant of 1.

156 ctions using Incomplete hierarchical LabeLs (PILL in short).

157 o measurements of the movement of a magnetic pill in the stomachs of fasted and fed humans.

158 rofile, parity and use of oral contraceptive pills in females, smoking and alcohol intake in males di

159 d direction of gastric forces experienced by pills in healthy stomachs serves as a baseline for compa

160 rate (TDF) and emtricitabine (FTC), the quad pill includes cobicistat (COBI; an inactivator of cytoch

161 adults 65 years of age or older, choking or pill-induced dysphagia or globus caused 37.6% (95% CI, 2

162 entified articles, recording treatment type (pill, injection, or other) and whether placebo compositi

163 The Matlab code of PILL is available upon request.

164 rologic and immunologic efficacy of the quad pill is equivalent to that of other comparator regimens

165 PILL is shown to outperform other related techniques in

166 The quad pill is the newest single-pill, once-daily option for th

167 Variation in the appearance of generic pills is associated with nonpersistent use of these esse

168 ien) is the most widely prescribed "sleeping pill." It makes the inhibitory neurotransmitter GABA wor

169 What our magnetic pill localization strategy adds to the state of the art,

170 combined oestrogen-progestagen contraceptive pill might decrease lamotrigine concentrations, which co

171 of medicines for dyspepsia (from 3.7 to 2.4 pills/month) and painkillers (6.8-5.5 pills/month) and t

172 to 2.4 pills/month) and painkillers (6.8-5.5 pills/month) and the number of antibiotic courses (0.6-0

173 device (LNG-IUD; n = 27), oral contraceptive pills (n = 32), or no hormonal contraception (n = 33).

174 ore sex and one dose within 24 h after sex), pills needed or used to achieve regimen-specific adheren

175 We included 21 nonoral contraceptive pill (non-OCP) users who self-collected vaginal samples

176 s and possibly lower adherence rates (due to pill number or complexity of regimen).

177 buttressed by a dose-response relation of PB pill number to chronic symptoms in GWV and by a relation

178 such that all volunteers received identical pill numbers.

179 ed after cessation of the oral contraceptive pill (OCP) and associated adenoma regression.

180 ons between sex hormones, oral contraceptive pill (OCP) use, systemic inflammation and airway inflamm

181 Oral contraceptive pills (OCPs) have been associated with improvement for m

182 associated with using pyridostigmine bromide pills [odds ratio (OR) = 3.5; 95% confidence interval (C

183 eatment group (daily intake of a combination pill of 2.5 mg folic acid, 50 mg vitamin B6, and 1 mg vi

184 Daily intake of a combination pill of 2.5 mg of folic acid, 50 mg of vitamin B6, and 1

185 rs of treatment and follow-up, a combination pill of folic acid, vitamin B6, and vitamin B12 did not

186 Participants took a median of 15 pills of TDF-FTC or placebo per month (P=0.57).

187 ability to monitor the force exerted by the pill on the tissue and to locate the magnetic pill withi

188 We compared 2 regimens dosed as 2 pills once daily.

189 The quad pill is the newest single-pill, once-daily option for the treatment of human immun

190 lity of the combination of simeprevir, a one-pill, once-daily, oral HCV NS3/4A protease inhibitor ver

191 fety of the combination of simeprevir, a one pill, once-daily, oral HCV NS3/4A protease inhibitor, pl

192 These extracellular structures, called pill or fimbriae, are employed in attachment and invasio

193 treat all only if statin cost exceeded $3.16/pill or if testing increased adherence from <22% to >75%

194 escribed in randomized, controlled trials of pills or capsules.

195 -associated factors (intake of birth control pills or estrogens and number of births) were not associ

196 uring treatment, those receiving CBI without pills or medical management (n = 157) had lower percent

197 re' placebos are interventions such as sugar pills or saline injections without direct pharmacologica

198 urred when the oral contraceptive pill ("the Pill" or "OCP") was approved.

199 ), nicotine patch (active patch plus placebo pill), or varenicline (active pill plus placebo patch),

200 control condition of psychotherapy, placebo, pill, or other treatment and samples of sufficient power

201 otein powder, soy protein powder and placebo pill, or venlafaxine and soy protein powder.

202 ception is superior to that of contraceptive pills, patch, or ring and is not altered in adolescents

203 eptive failure rate among participants using pills, patch, or ring was 4.55 per 100 participant-years

204 Among participants who used pills, patch, or ring, those who were less than 21 years

205 PAa, placebo acupuncture; placebo cetirizine pill, PC) and a no-intervention control (NI).

206 .5 : 1.5) during which each subject took one pill per day at the same clock time (3 mg melatonin or p

207 associations were among persons taking >1.5 pills per day for at least 10 years (odds ratio, 4.27; 9

208 performance on loss to follow-up and on-time pill pickup were explored, and appropriate corrective ac

209 Is but missed the desired target for on-time pill pickup, pharmacy stockouts, and virological suppres

210 Targets were missed for on-time pill pickup, retention in care, and virological suppress

211 s for rates of loss to follow-up and on-time pill pickup.

212 to -0.11), and SSRIs and SNRIs compared with pill placebo (-0.44, -0.67 to -0.22) were the only class

213 sure therapy and were randomly assigned to a pill placebo (n = 14) or 50 mg of DCS (n = 15) immediate

214 specific pharmacological effect relative to pill placebo for patients with less severe depression.

215 apy (CBT), and FLX/CBT combination (COMB) vs pill placebo in 439 adolescents with major depressive di

216 rapy was associated with fewer dropouts than pill placebo or medications.

217 avioral therapy, medication, combination, or pill placebo) in the Child/Adolescent Anxiety Multimodal

218 cessation with commonly used treatments (and pill placebo) lead to decreased alpha4beta2* nAChR densi

219 0 mg/d), (2) prolonged exposure therapy plus pill placebo, (3) supportive counseling plus naltrexone

220 al group therapy (CBGT), phenelzine sulfate, pill placebo, and combined CBGT plus phenelzine.

221 ong with the effect of low-dose varenicline, pill placebo, and smoking-to-satiety on withdrawal ratin

222 Compared with pill placebo, selective serotonin reuptake inhibitors (S

223 nitive-behavioral therapy, bupropion HCl, or pill placebo.

224 to SRIs was superior to both risperidone and pill placebo.

225 100 mg/d), or (4) supportive counseling plus pill placebo.

226 /RP (17 sessions delivered twice weekly), or pill placebo.

227 talopram; escitalopram plus CBT, followed by pill placebo; and escitalopram alone, followed by placeb

228 were assigned to 1 of 4 parallel groups: no pills, placebo pills (blinded), echinacea pills (blinded

229 :1:1 ratio), to 11 weeks of placebo (placebo pill plus placebo patch), nicotine patch (active patch p

230 h plus placebo pill), or varenicline (active pill plus placebo patch), plus behavioural counselling.

231 IV risk in ten studies of oral contraceptive pills (pooled HR 1.00, 0.86-1.16) or five studies of nor

232 o controls (sham acupuncture [SA] or placebo pills [PPs]).

233 iption rate data were expressed as number of pills prescribed per person.

234 was a wide variation in the number of opioid pills prescribed to patients undergoing the same operati

235 prescription data are expressed as number of pills prescribed.

236 ian Polycap Study], Poly-Iran, Wald, and the PILL [Program to Improve Life and Longevity] Collaborati

237 Yet, safe, effective pill retention within a desired region of the GI remains

238 costs (for repeat prescription), followed by pills running out, not wanting others to notice, side-ef

239 forward in the ability to localize magnetic pills safely and effectively anywhere within the GI trac

240 though prescription drugs (prescription pain pills, sedatives, and tranquilliser) were the most commo

241 s no significant association between placebo pills, sham acupuncture and cue conditioning effects, in

242 CI, 1.12 to 1.59]) and 66% after a change in pill shape (adjusted odds ratio, 1.66 [CI, 1.43 to 1.94]

243 of patients (3286 of 11,513) had a change in pill shape or color during the study.

244 that assessed the use of oral contraceptive pills showed no significant association with HIV acquisi

245 These contaminants are like gluten 'pills', shown here to skew gluten analysis results.

246 tend that an underappreciated consequence of pill size is unequal dosing in comparative clinical tria

247 The regimen comprised 3 pills taken daily.

248 mber of analgesic pills taken, and number of pills taken from day 3 to the end of the study correlate

249 fficulty with obtaining pills, and number of pills taken per day but did not vary by education level,

250 vation phase was change in the proportion of pills taken vs baseline; secondary end points were the a

251 3 weeks to assess pain, number of analgesic pills taken, and number of days pills were taken.

252 pills were taken, total number of analgesic pills taken, and number of pills taken from day 3 to the

253 conducted to determine the number of opioid pills taken.

254 PILL takes into account the hierarchical and the flat ta

255 We sought to measure the utility of daily pill-taking for cardiovascular prevention.

256 Disclosure was less common for pills than for injections and other treatments (8.2% vs.

257 es swallowing an optomechanically engineered pill that captures cross-sectional microscopic images of

258 t proportion of elderly people from taking a pill that would benefit only a few.

259 owledge could help in the design of sleeping pills that induce a more natural sleep.

260 obtained refills.We identified the number of pills that would fully supply the opioid needs of 80% of

261 hows that it might be possible to develop a 'pill' that awakens the innate immune system to kill canc

262 debate occurred when the oral contraceptive pill ("the Pill" or "OCP") was approved.

263 The median velocity of the magnetic pill through the small intestine in the fasting state wa

264 her, was the median velocity of the magnetic pill through the small intestine in the postprandial sta

265 e-blinded randomized trial comparing placebo pill to duloxetine.

266 " only 34.7% could demonstrate the number of pills to be taken daily.

267 rocedures and to estimate an ideal number of pills to prescribe.

268 described can be applied to high-resolution pill tracking acquired by any modality.

269 ed contraceptive methods (oral contraceptive pills, transdermal patch, contraceptive vaginal ring, an

270 preferred; and at costs less than $0.10 per pill, treating all persons with low-density lipoprotein

271 1 (n = 17) was a 2-wk single-blinded placebo pill trial.

272 of 20 mg of doxycycline or matching placebo pill twice a day at least 2 days prior to surgery, on th

273 ed), echinacea pills (blinded), or echinacea pills (unblinded, open-label).

274 in the TDF-FTC group had evidence of recent pill use at visits that were matched to the HIV-infectio

275 lation factors, prolonged oral contraceptive pill use provided a greater protective effect against pr

276 Current and previous contraceptive pill use was assessed by a questionnaire.

277 d vomiting, laxative use, diuretic use, diet pill use, driven exercise).

278 iabetes mellitus, cancer, oral contraceptive pill use, surgical menopause, hormone replacement therap

279 t be explained by differential contraceptive pill use.

280 ales were not matched for oral contraceptive pill use.

281 Current pill users had deeper mean probing depths compared to no

282 Pill users had more sites with bleeding on probing (44.0

283 The periodontal health of current pill users was compared to that of women not taking the

284 molecules varied between oral contraceptive pill users, postmenopausal females, and females in the f

285 This approach was exemplified on QiShenYiQi Pills using thrombin and angiotensin converting enzyme a

286 pilus-mediated conjugal transfer, as well as pilL-V, which encodes a second pilus of the type IV fami

287 or 12 weeks: milk protein powder and placebo pill, venlafaxine and milk protein powder, soy protein p

288 ps, and compliance with the study powder and pills was 80-90%.

289 osage, supply days, and numbers of dispensed pills was extracted from the Taiwan National Health Insu

290 enicline and twice while receiving a placebo pill, wearing either a nicotine or a placebo patch.

291 d core temperature via ingestible telemetric pill were measured continuously; cutaneous vascular cond

292 Fewer pills were needed for complete adherence in women alloca

293 udy population, the number of days analgesic pills were taken, total number of analgesic pills taken,

294 of analgesic pills taken, and number of days pills were taken.

295 Only 28% of the prescribed pills were taken.

296 randomly assigned (1:1) to receive either a pill with active pre-exposure prophylaxis or placebo, ta

297 t was change in the velocity of the magnetic pill within the small intestine.

298 ill on the tissue and to locate the magnetic pill within the test subject all in real time.

299 ndent of the distribution of the capsules or pills within the RF coil and is therefore more suitable

300 jury when they are treated with the sleeping pill zolpidem.