ライフサイエンスコーパス: pincer

1 ](2-) ligand coordinates as a kappa(3)-O,P,O pincer.

2 is the first enzyme known to possess a metal pincer active site.

3 ymerization results for the first trianionic pincer alkylidyne complex, [(t)BuOCO]W identical withCC(

4 PNP (PNP- = N[2-P(CHMe2)2-4-methylphenyl]2) pincer ancillary bound to nickel.

5 ) metal phosphors bearing both the dicarbene pincer ancillary such as 2,6-diimidazolylidene benzene a

6 nteresting applications employing trianionic pincer and pincer-type complexes include: (1) catalyzed

7 Trianionic pincer and pincer-type ligands are the focus of this rev

8 The type of donor atoms within trianionic pincer and pincer-type ligands to be discussed include:

9 Since this is the first review of trianionic pincer and pincer-type ligands, an emphasis is placed on

10 s validate that both of the RNAP crab claw's pincers are mobile, as both beta and beta' have substant

11 yl and iron alkoxide complexes bearing boxmi pincers as stereodirecting ligands have been employed as

12 results demonstrate the strong influence of pincer backbone and hydrosilane sterics on the different

13 ithin the secondary coordination sphere of a pincer-based Fe(II) complex provides Lewis acidic sites

14 I)-(N2) precursor supported by a monoanionic pincer bis(carbene) ligand, (Mes)CCC ((Mes)CCC = bis(mes

15 l % of Rh catalyst supported by a new chiral pincer carbodicarbene ligand that delivers allylic subst

16 ommercially available ruthenium(II) PNP-type pincer catalyst (Ru-Macho) promotes the formation of alp

17 context we have examined the use of iridium pincer catalysts for the hydrosilylative reduction of su

18 droproducts (e.g., Ir and Rh diphosphine and pincer catalysts).

19 A highly efficient ruthenium pincer-catalyzed Guerbet-type process for the production

20 orm the organic component of the (SCS)Ni(II) pincer cofactor of LarA.

21 e was no prior evidence for the existence of pincer cofactors in enzymes.

22 coupling catalyzed by a preformed nickel(II) pincer complex ([(N2N)Ni-Cl]).

23 e alkynyl C-H bond of phenylacetylene to the pincer complex (PCP)Ir(CO).

24 Rhodium-hydride PNP pincer complex 1 is shown to add CO2 in two disparate pa

25 ng water as the only reagent is catalyzed by pincer complex 2.

26 The cationic iridium pincer complex [(POCOP)Ir(H)(acetone)](+)[B(C(6)F(5))(4)

27 The nonclassical ruthenium hydride pincer complex [Ru(PNP)(H)(2)(H(2))] 1 (PNP = 1,3-bis(di

28 (C6H2(t)Bu2-3,5-O-4)(2-), in the Bi(3+) NCN pincer complex Ar'Bi(C6H2(t)Bu2-3,5-O-4), 1, [Ar' = 2,6-

29 The Bi(3+) (N,C,N)-pincer complex Ar'BiCl(2) (1) [Ar' = 2,6-(Me(2)NCH(2))(2

30 The first Pd-pincer complex bearing a halogen (fluorine) arm has been

31 actobacillus plantarum harbors a (SCS)Ni(II) pincer complex derived from nicotinic acid.

32 nt, this pathway could be used to generate a pincer complex in other enzymes.

33 ydrosilylation catalyzed by the iridium(III) pincer complex introduced by Brookhart.

34 ed at 20 degrees C using Brookhart's Ir(III) pincer complex IrH(2)POCOP (5) (POCOP = [mu(3)-1,3-(OPtB

35 The reaction is catalyzed by a pincer complex of an earth-abundant metal (manganese), i

36 The reaction is catalyzed by a pincer complex of the earth abundant manganese and forms

37 A new de-aromatized pyridine-based PNP pincer complex of the Earth-abundant, first-row transiti

38 A hydride Mn(I) PNP pincer complex recently developed in our laboratory cata

39 tethered to Lys(184) and forms a tridentate pincer complex that coordinates nickel through one metal

40 d by a well-defined acridine-based ruthenium pincer complex was investigated in detail by both experi

41 In a preliminary study, a related Fe(II) PNP pincer complex was shown to catalyze the methylation of

42 An air- and moisture-stable SeCSe-Pd(II) pincer complex was synthesized and found to catalyze the

43 elimination of methane and formation of the pincer complex, [kappa(3)-Ar(Tol'(2))]Ta(PMe(3))(2)MeCl

44 n or added oxidant, catalyzed by a ruthenium pincer complex, is developed.

45 A well-defined hydride Mn(I) PNP pincer complex, recently developed in our laboratory, ca

46 mentary recognition unit, a p-methoxy SCS-Pd pincer complex.

47 New carbazolide-based iridium pincer complexes ((carb)PNP)Ir(C2H4), 3a, and ((carb)PNP

48 ) has been constructed from Pd diphosphinite pincer complexes ([L-PdX](4-) = [(2,6-(OPAr2)2C6H3)PdX](

49 A series of new bis(phosphinite) p-XPCPIrHCl pincer complexes ([PCP = eta(3)-5-X-C(6)H(2)[OP(tBu)(2)]

50 Reaction of bis(phosphinite) PCP iridium pincer complexes (p-XPCP)IrHCl (5a-f) [X = MeO (5a), Me

51 of the phenylhydrosilanes PhnSiH4-n with the pincer complexes (POCsp(2)OP)Ni(OSiMe3), 1-OSiMe3, and (

52 Ir pincer complexes [((t)BuPNP)Ir(R)] (R = C6H5 (1), CH2COC

53 Random copolymers possessing both palladated-pincer complexes and diaminopyridine moieties (hydrogen-

54 s serves as the first example of boron-metal pincer complexes and possesses several interesting elect

55 tion of secondary alcohols and diols on iron pincer complexes and reversible oxidative dehydrogenatio

56 The activation of carbodicarbene (CDC)-Rh(I) pincer complexes by secondary binding of metal salts is

57 the synthesis of several unique, boron-rich pincer complexes derived from m-carborane.

58 The new Pt(II) pincer complexes display very high luminescence quantum

59 th HBpin (pin = pinacolate) using POCOP-type pincer complexes of Ir has been demonstrated, with turno

60 Pincer complexes of the type ((R)PCP)IrH(2), where ((R)P

61 ons in transition-metal chemistry to furnish pincer complexes or "pogo stick" type compounds.

62 Six amide-based NNN palladium(II) pincer complexes Pd(L)(CH3CN) were synthesized, characte

63 The first [ECE]Ni(II) pincer complexes with E = Si(II) and E = Ge(II) metallyl

64 ghtest binding ligands toward the palladated pincer complexes with the alanyl derivative being the st

65 A series of iron bis(phosphinite) pincer complexes with the formula of [2,6-((i)Pr2PO)2C6H

66 chelate yielding the corresponding modified pincer complexes, ((tBu)mPNP)CoX (X = H, CH3, Cl, CCPh).

67 nd reactivity of unusual T-shaped (LXL)Au(I)-pincer complexes, based on a carbazole framework flanked

68 PN5P-Ir-pincer complexes, recently developed in our laboratory,

69 activation by ligand cooperativity in nickel pincer complexes.

70 ents between appropriate intact and modified pincer complexes.

71 oxylation of unactivated olefins by iridium "pincer" complexes.

72 ist-led information technology intervention (PINCER), composed of feedback, educational outreach, and

73 ioxyselenuranes and diminished activity when pincer compounds were produced.

74 A V-shaped pincer connects HEL2 and the CTD by gripping an alpha-he

75 In this way, the pincer coordinates functions of all the domains and coup

76 The pincer-crown ether ligand exhibits tridentate, tetradent

77 ion ligated in a pentadentate fashion by the pincer-crown ether ligand.

78 ali metal cation binding with a macrocyclic "pincer-crown ether" ligand.

79 Our approach was to use molecular pincer design in which a pair of antibodies recognizing

80 An iridium pincer dihydride catalyst was immobilized on carbon nano

81 ral studies of RIG-I have identified a novel Pincer domain composed of two alpha helices that physica

82 ophysical analysis, we further show that the Pincer domain controls coupled enzymatic activity of the

83 pathic helix (the basic amino acid PI(4,5)P2 pincer domain) was required for PI(4,5)P2 binding and re

84 evolved to potentiate interactions with the Pincer domain, resulting in an adapted ATPase cleft that

85 eview is structured according to the type of pincer donor atoms that bind to the metal ion.

86 activation within the strained m-carboranyl pincer framework.

87 ring Rh and the chelating aryl carbon of the pincer framework.

88 h which they use chopsticks, handedness, and pincer grip activities.

89 her activities and subjects who denied other pincer grip activities.

90 and subjects who did not engage in any other pincer grip activities.

91 This suggests that RNA polymerase II's pincer grip is important as it slides on DNA in search o

92 At 6 months' follow-up, patients in the PINCER group were significantly less likely to have been

93 PINCER has a 95% probability of being cost effective if

94 led that borylation of the 4-position of the pincer in the cobalt catalyst was faster than arene bory

95 INTERPRETATION: The PINCER intervention is an effective method for reducing

96 This analysis suggests that the PINCER intervention is strongly effective in reducing th

97 ium centre in molecular single crystals of a pincer Ir(I) complex.

98 not the thermodynamics) of C-H addition to (pincer)Ir are favored by sigma-withdrawal from the phosp

99 e to unsubstituted PCP) addition to the 14e (pincer)Ir fragments but disfavor addition to the 16e com

100 y proceeds via alpha-olefin C-H addition to (pincer)Ir to give an allyl intermediate as was previousl

101 tion to the 16e complexes (pincer)IrH(2) or (pincer)Ir(CO).

102 Instead, (pincer)Ir(eta(2)-olefin) species undergo isomerization v

103 undergo isomerization via the formation of (pincer)Ir(eta(3)-allyl)(H) intermediates; one example of

104 on, which limits yields of alpha-olefin from pincer-Ir catalyzed alkane dehydrogenation, proceeds via

105 but disfavor addition to the 16e complexes (pincer)IrH(2) or (pincer)Ir(CO).

106 The corresponding dihydrides, (pincer)IrH(2), are known to hydrogenate olefins via init

107 ydroaryloxylation of aryl alkyl ethers using pincer iridium catalysts.

108 mation within a nonporous molecular crystal: pincer iridium single crystals ligated with nitrogen, et

109 The pincer-iridium fragment ((iPr)PCP)Ir ((R)PCP = kappa(3)-

110 feature a rare nickel-carbene linkage as the pincer ligand anchor point.

111 ing a tridentate 2,6-pyridinedicarboxamidate pincer ligand and a terminal hydroxide ligand.

112 s supported by a naphthyridine-diimine (NDI) pincer ligand as functional surrogates of Co2 (CO)8 .

113 coupled electron transfer from the saturated pincer ligand backbone.

114 -)) that are deprotonated at nitrogen in the pincer ligand backbone.

115 y(NMes)) was prepared as a rigid, tridentate pincer ligand containing pendent anilines as hydrogen bo

116 e incorporation of the metal center into the pincer ligand decreases the NICS(1)zz values.

117 mplex (3) supported by a bis(phosphino)amine pincer ligand efficiently catalyzes both acceptorless de

118 nt the up to now strongest chelating neutral pincer ligand for the simplest electrophile of chemistry

119 A new class of [CCC] X(3)-donor pincer ligand for transition metals has been constructed

120 Nickel complexes of a PC(carbene)P pincer ligand framework are described.

121 A new bifunctional pincer ligand framework bearing pendent proton-responsiv

122 emase, which features a pyridinium-based SCS pincer ligand framework bound to nickel.

123 A tetra(carboxylated) PCP pincer ligand has been synthesized as a building block f

124 idinedicarboxamidate(2-)) derived from a NNN pincer ligand have been prepared including L = OH(-) (1)

125 [ReCl3(PPh3)2(NCMe)] reacts with pincer ligand HN(CH2CH2PtBu2)2 (HPNP) to five coordinate

126 possible involvement of the N-H group on the pincer ligand in the catalysis via a metal-ligand cooper

127 (3))(2)(CD(3))(3)Cl(2) demonstrates that the pincer ligand is created by a pair of Ar-H/Ta-Me sigma-b

128 e (tBu) PCP (kappa(3)-2,6-((t)Bu2PCH2)2C6H3) pincer ligand is possible.

129 strongly trans directing silyl group at the pincer ligand of these complexes are discussed on the ba

130 A carbodicarbene (CDC)-based pincer ligand scaffold is reported, along with its appli

131 ungsten catalyst supported by a tetraanionic pincer ligand that can rapidly polymerize alkynes to for

132 atalyst appears to be the new ancillary SiNN pincer ligand that combines amido, quinoline, and silyl

133 Application of a tridentate NHC containing pincer ligand to Pt catalyzed cascade cyclization reacti

134 The basicity of the ipso-carbon atom of the pincer ligand was investigated in a related complex.

135 A new PC(carbene)P pincer ligand with 2,3-benzo[b]thiophene linkers connect

136 e (PCP)Ir(I) fragment containing an aromatic pincer ligand with methyl-substituted hydrazines form a

137 -innocent pyrrole-based trianionic (ONO)(3-) pincer ligand within [(pyr-ONO)TiCl(thf)2 ] (2) can acce

138 The complex containing an aromatic pincer ligand, (PCP)Ir(H)(NHNC(5)H(10)), slowly undergoe

139 New iridium complexes of a tridentate pincer ligand, 2,6-bis(di-tert-butylphosphinito)pyridine

140 I)(OH)(n)(H(2)O)(m), 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to cata

141 = CCH3(CF3)2) 1, featuring a stabilizing ONO pincer ligand, initiates the controlled living polymeriz

142 ploying an iron-based catalyst bearing a PNP-pincer ligand.

143 bonds in remote positions of the supporting pincer ligand.

144 highly reversible C-C coupling with the PNP pincer ligand.

145 ered alkylidene (4) featuring a tetraanionic pincer ligand.

146 ormational flexibility of the acridine-based pincer ligand.

147 ed by an iridium complex supported by a SiNN pincer ligand.

148 reacting silver(I) oxide with N-substituted pincer ligands 3 (a = 2,6-bis(ethanolimidazoliummethyl)p

149 The concept of aromaticity in pincer ligands and complexes was discussed in order to p

150 aromatic PN(x)(P) and dearomatized PN(x)(P)* pincer ligands and the corresponding transition metal co

151 Palladium complexes with chiral pincer ligands are demonstrated to have utility in deter

152 s of the process when different dearomatized pincer ligands are used.

153 The SeBSe and SBS pincer ligands can be synthesized via two independent sy

154 ert-butyl substituted bis(phosphino)pyridine pincer ligands has been synthesized and structurally cha

155 eric and electronic properties of trianionic pincer ligands has occurred rapidly over the past ten ye

156 able tridentate directing groups inspired by pincer ligands have been designed to stabilize otherwise

157 Cobalt(II) alkyl complexes of aliphatic PNP pincer ligands have been synthesized and characterized.

158 The increase in use of pincer ligands in forming stable, isolable complexes is

159 um dihydride complexes supported by PCP-type pincer ligands rapidly insert CO(2) to yield kappa(2)-fo

160 Iridium complexes of sterically unhindered pincer ligands such as (iPr4)PCP, in the solid phase, ar

161 he rare earths, are combined with trianionic pincer ligands to produce some of the most interesting c

162 es of aromatic (PCP) and aliphatic (D(t)BPP) pincer ligands undergo single cleavage of the N-H bonds

163 is is put on the common appearance in AAD of pincer ligands, of noninnocent ligands, and of outer sph

164 Cobalt complexes stabilized with pincer ligands, recently developed in our laboratory, ca

165 hilic traps with electrophilic trisphosphine pincer ligated Pt(II) complexes results in the formation

166 system comprises one molecular catalyst (a "pincer"-ligated iridium complex) that effects alkane deh

167 eneous or molecular catalysts--specifically 'pincer'-ligated iridium complexes--and olefinic hydrogen

168 R)POCOP = kappa(3)-C(6)H(3)-2,6-(OPR(2))(2)) pincer-ligated catalysts, which also show catalytic acti

169 A family of pincer-ligated cobalt complexes has been synthesized and

170 alkanes catalyzed by solid-phase, molecular, pincer-ligated iridium catalysts, using ethylene or prop

171 process involves alkane dehydrogenation by a pincer-ligated iridium complex and alkene dimerization b

172 A pincer-ligated iridium complex, (PCP)Ir (PCP = kappa(3)-

173 le (H(2), arene, alkane, and CO) addition to pincer-ligated iridium complexes of several different co

174 The p-methoxy-substituted pincer-ligated iridium complexes, (MeO-(tBu)PCP)IrH(4) (

175 isomerization of olefins by complexes of the pincer-ligated iridium species ((tBu)PCP)Ir ((tBu)PCP =

176 The pincer-ligated species (PCP)Ir (PCP = kappa3-C6H3-2,6-(C

177 to date in this area has been achieved with pincer-ligated transition-metal-based catalysts; this an

178 The pincer-like 1,3-alternate conformation of the oxacalix[4

179 ich the carboxy-terminal tail domain is held pincer-like by the vinculin head, and ligand binding is

180 m152 interacts in a pincer-like manner with two sites on the alpha1 and alph

181 releasing" motions between vinculin tail and pincer-like structure formed by first three domains of v

182 suggest that a wide family of pyridine-based pincers may also be redox-active.

183 anion receptor functions via a novel dynamic pincer mechanism where upon nitrate anion binding, both

184 es, and catalytic applications of trianionic pincer metal complexes.

185 s tandem [4 + 2]/[4 + 2] cycloadditions in a pincer mode.

186 u)PNP)CoH, at 110 degrees C also resulted in pincer modification by H atom loss while the chloride an

187 es of mutations that additively decouple the Pincer motif from the ATPase core and show that this dec

188 igher binding ability offered by two pendant pincers of the former.

189 , a C51 H24 hydrocarbon with two corannulene pincers on a dibenzonorbornadiene tether, exhibits an af

190 ionally fixed aromatic residues, hydrophobic pincer pair that locks the different drug structures on

191 ppendages approximately perpendicular to the pincer plane, with increasingly better alignment progres

192 We find that the Pincer plays an important role in mediating the enzymati

193 ssociation constants are comparable to other pincer-pyridine systems in DMSO suggesting that the cont

194 the controlled coordination of the metalated pincer/pyridine interaction is an interesting biological

195 imary alcohols, alkyl chains, and palladated pincer receptors, synthesized by ring-opening metathesis

196 inant spherocytosis and with the presence of pincered red cells in the peripheral blood smears of uns

197 2 featuring one and two pendant amide side "pincers", respectively, and three triphenylamine substit

198 This article describes a well-defined pincer-Rh catalyst for C-S cross-coupling reactions.

199 f Milstein's well-defined acridine-based PNP-pincer Ru complex has been investigated both experimenta

200 The reaction is catalyzed by a PNP pincer ruthenium complex, generating efficiently only di

201 ligand combining a rigid, strongly donating pincer scaffold with a flexible, weakly donating aza-cro

202 In contrast, several selenides that afford pincer selenuranes (e.g., 20 and 21) instead of spirosel

203 red which specifically binds Ni(II) at a NNN pincer site and five-coordinate Fe(II) at a triamine sit

204 The PINCER study, a cluster randomised controlled trial, is

205 analogous diarylamido/bis(phosphine) (PNP)Rh pincer system.

206 havior of isoelectronic Mn(I) and Fe(II) PNP pincer systems.

207 ibody-based protein sensor design (molecular pincers) that allows rapid and sensitive detection of a

208 rization of the new CF(3)-ONO(3-) trianionic pincer tungsten-alkylidene [CF(3)-ONO]W horizontal lineC

209 esign of highly basic nonionic superbases of pincer type.

210 The square planar pincer-type carbene effects quantitative oxygen-atom tra

211 applications employing trianionic pincer and pincer-type complexes include: (1) catalyzed aerobic oxi

212 Patients with pincer-type FAI had a significantly larger femoral antet

213 on was significantly higher in patients with pincer-type FAI than in those with cam-type FAI for read

214 [C(CF3)2O])2N(3-)} supported by a trianionic pincer-type ligand demonstrates enhanced nucleophilicity

215 rization of a novel CF(3)-ONO(3-) trianionic pincer-type ligand, rationally designed to mimic enamine

216 Pincer-type ligands are believed to be very robust scaff

217 Trianionic pincer and pincer-type ligands are the focus of this review.

218 yhydride complexes containing tridentate PNP pincer-type ligands is described.

219 of donor atoms within trianionic pincer and pincer-type ligands to be discussed include: NCN(3-), OC

220 is the first review of trianionic pincer and pincer-type ligands, an emphasis is placed on providing

221 Here we design a Pt(II) pincer-type material with selective absorptive and emiss

222 was observed in the analogous complex with a pincer-type mer-C,N,S ligation, emphasizing the importan

223 d the problem of high prevalence of cam- and pincer-type morphology in asymptomatic persons.

224 of arylboronic acids catalyzed by a new ONO pincer-type Pd(II) complex under mild reaction condition

225 Theoretically designed pincer-type phosphorus compound is found to be active fo