ライフサイエンスコーパス: pineal gland

1 the pattern of melatonin secretion from the pineal gland.

2 hotoreceptor system for regulating the human pineal gland.

3 nates is comparable to that of the night rat pineal gland.

4 GC in photoreceptors, was not present in the pineal gland.

5 presence of ROS-GC2 was not detected in the pineal gland.

6 k, and MOP4) are co-expressed in the chicken pineal gland.

7 te cyclase signal transduction system in the pineal gland.

8 the eye and of pineal-specific genes in the pineal gland.

9 rs of the retina and the pinealocytes of the pineal gland.

10 n, mesencephalon, cerebellum, pituitary, and pineal gland.

11 y expressed in the retina and AANAT-2 in the pineal gland.

12 tion between P(Pm) and other proteins in the pineal gland.

13 r by reducing production of melatonin by the pineal gland.

14 ols the rhythm in melatonin synthesis in the pineal gland.

15 ulator of Gbetagamma signaling in retina and pineal gland.

16 al medulla, the posterior pituitary, and the pineal gland.

17 hm in melatonin production in the vertebrate pineal gland.

18 in neuroendocrine functions, possibly in the pineal gland.

19 only localized to the retina but also to the pineal gland.

20 role in regulating circadian rhythm in chick pineal gland.

21 iencephalic tract in Alligator which lacks a pineal gland.

22 alocyte, the melatonin-secreting cell of the pineal gland.

23 Ribeye b is absent in the pineal gland.

24 e retina and a subset of pinealocytes in the pineal gland.

25 ates photoneural-circadian regulation of the pineal gland.

26 se (MAT), increases 2.5-fold at night in the pineal gland.

27 candidate opsinlike genes in the retina and pineal gland.

28 of the retina and in the pinealocytes of the pineal gland.

29 of the retina and in the pinealocytes of the pineal gland.

30 zebrafish crx is expressed in the retina and pineal gland.

31 ein is detectable in both the retina and the pineal gland.

32 , is expressed selectively in the retina and pineal gland.

33 OST2) is predominantly restricted to daytime pineal glands.

34 3 and miR-96 are also highly enriched in the pineal gland, a distinctive pattern also found in the re

35 ovide evidence for amphioxus homologs of the pineal gland, adenohypophysis, and endocrine pancreas.

36 expectation was examined with respect to the pineal gland, an organ innervated by the two SCGs.

37 d to one of three photosensitive organs (the pineal gland and both eyes) can protect the eyes from th

38 thm of plasma melatonin originating from the pineal gland and driven by the circadian pacemaker locat

39 in distal intracranial SCG targets, such as pineal gland and extracerebral blood vessels (bv).

40 Unlike pineal gland and extracerebral bv, the external carotid

41 n of pgPepT1 appears to be restricted to the pineal gland and follows a marked circadian pattern with

42 dorsal structures, including the developing pineal gland and habenular nucleus, both implicated in C

43 at TPH1 is the predominant form expressed in pineal gland and in P815 mastocytoma cells with a molecu

44 e of two putative photoisomerases within the pineal gland and in retinal layers associated with biolo

45 Localization of AT transcripts in the pineal gland and in specific cells of the intestine, cer

46 -binding proteoglycan that is present in the pineal gland and interphotoreceptor matrix of the retina

47 pproximately 1 kb) is highly abundant in the pineal gland and is expressed at lower levels in the ret

48 VT-AANAT contributed to the evolution of the pineal gland and lateral eyes from a common ancestral ph

49 ression was detected in the hypothalamus and pineal gland and reiterates Bsx expression.

50 e tissue-specific gene expression within the pineal gland and retina derives, in part, from a pineal/

51 The mRNA for both genes within the pineal gland and retina is regulated on a circadian basi

52 n exhibits a dramatic diurnal rhythm in both pineal gland and retina with 100-fold greater expression

53 l of HIOMT mRNA fluctuates daily in both the pineal gland and retina.

54 AT), which is predominantly expressed in the pineal gland and retina.

55 es were predominantly distributed within the pineal gland and retina: the retinal pigmented epitheliu

56 In birds, the pineal gland and retinae have been defined as pacemakers

57 crease in beta4 and alpha3 expression in the pineal gland and SCG.

58 concentrations of paraquat were seen in the pineal gland and the lateral ventricles.

59 daily changes in melatonin production by the pineal gland and thereby plays a unique role in biologic

60 rom several experiments performed on the rat pineal gland and Toxoplasma gondii, successfully detecti

61 Surgery reliably reset the phase of the pineal gland and vascular organ of the lamina terminalis

62 sustained circadian oscillators, whereas the pineal gland and VOLT are weak oscillators that require

63 nt shark) were cloned, and it was found that pineal glands and retinas from these groups express a fo

64 mission in adrenal gland, autonomic ganglia, pineal gland, and several nuclei in the central nervous

65 ity of approximately 100 pM to nAChRs in the pineal gland, and the density of these sites is approxim

66 of nicotinic drugs for binding sites in the pineal gland are similar to those at alpha3beta4 nAChRs

67 that virtually all of the nAChRs in the rat pineal gland are the alpha3beta4 nAChR subtype and that

68 Levels in the pineal gland are the highest of any mammalian tissue.

69 r cells at embryonic day 16 (E16) and in the pineal gland at E21.

70 athetic neurotransmitter that stimulates the pineal gland at night.

71 cadian axis, the suprachiasmatic nucleus and pineal gland, but not in other brain areas examined.

72 increases in acetylation of serotonin in the pineal gland by arylalkylamine N-acetyltransferase (AANA

73 or matrix by Postnatal day 5 (P5) and in the pineal gland by P6.

74 elatonin is synthesized predominantly in the pineal gland by the actions of two pineal-specific enzym

75 Although 12L/12D covering of the pineal gland can protect chick eyes from CL's effects (c

76 e the alpha3beta4 nAChR subtype and that the pineal gland can therefore serve as an excellent and con

77 t sequences were masked, 26 novel retina and pineal gland cDNA clusters were identified.

78 that is mostly expressed in hypothalamic and pineal gland cells.

79 These pineal gland changes suggest that the pinealitis associa

80 e the existence of a functional HCRT neurons-pineal gland circuit able to modulate melatonin producti

81 in DNA from retinal photoreceptor cells and pineal gland compared to DNA from other tissues.

82 Binding studies in human and rat brain and pineal gland confirmed the selectivity of AT-1001 for al

83 Ribbon synapses of the ear, eye and pineal gland contain a unique protein component: Ribeye.

84 III-V, VIII, and IX of the spinal cord, and pineal gland contained exclusively ER-beta mRNA.

85 The rat pineal gland contains a high density of neuronal nicotin

86 lkylamine N-acetyltransferase, AANAT) in the pineal gland control the rhythmic production of the time

87 Overall, 34 patients (8%) manifested pineal gland cyst and 4 (1%) showed pineoblastoma.

88 Pineal gland cyst was incidentally detected in 8% of ret

89 on and protein appearance during retinal and pineal gland development in the rat.

90 of the anterior chamber, and hyperopia), the pineal gland does not appear to be necessary for normal

91 melatonin synthesis, is reduced in hcrtr-/- pineal gland during the night.

92 During development, the abundance of most pineal gland-enriched miRNAs increases; however, there i

93 The chick retina and pineal gland exhibit circadian oscillations in biochemic

94 Secretory cells of the chicken pineal gland exhibit light-sensitive circadian rhythms i

95 nce of AA-NAT protein in both the retina and pineal gland exhibited a daily rhythm that was statistic

96 cetyltransferase, AANAT) mRNA in the chicken pineal gland exhibits a circadian rhythm, which is trans

97 The pineal gland expresses a unique member of the opsin fami

98 tis, pinealitis has been demonstrated in the pineal gland from a mare with active uveitis and is susp

99 ur understanding of the 24-h dynamics of the pineal gland from one focused on melatonin synthesis to

100 B lymphocytes were detected only in the pineal gland from the one mare with active uveitis in wh

101 Pineal glands from 10 horses with uveitis and from 13 ho

102 Study of pineal glands from horses with clinically documented uve

103 P or vimentin immunoreactivity were noted in pineal glands from horses with or without uveitis.

104 Septal areas of pineal glands from horses with uveitis had clusters of M

105 We have evaluated pineal glands from horses with various stages of uveitis

106 hese changes were not as readily observed in pineal glands from horses without uveitis.

107 In this study, pineal gland function was examined by measuring nocturna

108 In the pineal gland, GLAST is expressed by astrocytic cells nea

109 In the pineal gland, gRgr message was sparsely distributed amon

110 octurnal melatonin signal generated from the pineal gland has been co-opted to provide the photoperio

111 Over the last several decades the pineal gland has emerged as an active neuroendocrine tra

112 Melatonin, the chief hormone secreted by the pineal gland, has been previously shown to inhibit human

113 Pineal gland hoods and eye covers worn 12 hours a day si

114 Numerous physiological functions of the pineal gland hormone melatonin are mediated via activati

115 ysiological or pharmacological levels of the pineal gland hormone melatonin, although the mechanism(s

116 The agrp2 gene was expressed in the pineal gland in a previously uncharacterized subgroup of

117 f serotonergic areas and melatonin-producing pineal gland in rat brains.

118 ), the immediate precursor of melatonin, the pineal gland indole, is regulated in a circadian rhythm.

119 reover, HCRT perfusion of cultured zebrafish pineal glands induces melatonin release.

120 s containing synaptic ribbons, including the pineal gland, inner ear, and retina.

121 t serotonin/melatonin-producing cells of the pineal gland into cells that also produce dopamine and i

122 The mammalian pineal gland is a neuroendocrine organ that responds to

123 cadian expression of FcepsilonRIalpha in the pineal gland is driven by this neural circuit via an adr

124 Melatonin production in the chick pineal gland is high at night and low during the day.

125 elatonin, the chief secretory product of the pineal gland, is a direct free radical scavenger, an ind

126 ation of rod transducin and suggest that the pineal gland may contain a rodlike phototransduction cas

127 and protein expression were detected in the pineal gland, medial mammillary nucleus, median eminence

128 ated by focusing on the main function of the pineal gland, melatonin synthesis.

129 cluding areas such as the subfornical organ, pineal gland, neurohypophysis, and hypothalamus.

130 transfected neuronal cells and in rat brain pineal gland, nucleus accumbens, and globus pallidus.

131 iurnal rhythm of melatonin production in the pineal gland of animals and humans.

132 Inflammation of the pineal gland of immunized rats suggests that P gamma is

133 Arg8-vasotocin isolated from the pineal gland of rainbow trout is detected, demonstrating

134 mined that a nonretinal P(Cl) pigment in the pineal gland of the pigeon has a lambdamax value at 481

135 P specifically to rod photoreceptors and the pineal gland of transgenic mice.

136 vertebrate-specific structures including the pineal gland, olfactory bulb, and brachial arches.

137 gths of light but does not require the eyes, pineal gland, or other canonical deep-brain photorecepti

138 the substantia nigra/pars compacta, and the pineal gland, partially overlapping SNAP-25b mRNA distri

139 The pineal gland plays an essential role in vertebrate chron

140 hythmic nocturnal melatonin signals from the pineal gland, providing a critical cue to time seasonal

141 Here, we demonstrate that in the mammalian pineal gland, ptc1 expression exhibits a dramatic diurna

142 of two key influx nodes at the pituitary and pineal gland recesses, while dynamic MRI permitted the d

143 expressed greater than 8-fold higher in the pineal gland relative to other tissues.

144 vated by 12 weeks, yet TH innervation of the pineal gland remained significantly decreased.

145 Pineal glands removed from neonatal rats at 5, 7, and 9

146 ealed mRNA expression for both opsins in the pineal gland, retina, and brain tissue.

147 Among its oscillators are the pineal gland, retinae, and a hypothalamic structure assu

148 We have cloned and sequenced the pineal gland-specific opsin (P opsin) gene, p(Pm), of ma

149 The chicken gene encoding pineal gland-specific opsin (P-opsin) has been previousl

150 A retina- and pineal gland-specific transcription factor, cone-rod hom

151 h factor (NGF) in the control and transgenic pineal glands, suggesting that it occurred in a NGF-inde

152 ine and murine tissues (whole brain, retina, pineal gland, superior colliculus, cortex, thymus, haben

153 Half of the chicks in each group had their pineal glands surgically removed at 3 to 6 days after ha

154 gene product has been identified in the rat pineal gland, termed pgPepT1.

155 us, mammillary bodies, substantia nigra, and pineal glands the two isoforms were distributed in recip

156 n we employ high density cDNA microarrays of pineal gland transcripts to determine oscillating transc

157 Studies have shown that the pineal gland via its hormone, melatonin, induces the inv

158 y (MCA)], the submandibular gland (SMG), and pineal gland was quantified following injury using an an

159 etic resonance imaging (MRI) features of the pineal gland were evaluated in all patients with retinob

160 l and histopathologic changes in the eye and pineal gland were examined.

161 The night levels of MAT2A mRNA in the pineal gland were severalfold higher than in other neura

162 T neuroanatomy, including projections to the pineal gland, where hcrtr mRNA is expressed.

163 o be related to the regulation of the nearby pineal gland (which Rene Descartes described as the "pri

164 to continuous stimulation in contrast to the pineal gland, which (being insulated from the external e

165 The chicken pineal gland, which contains a heterogeneous cell popula

166 12 lncRNAs (0.3 to >50 kb) occurs in the rat pineal gland, which is the source of melatonin, the horm

167 hythm in mRNA-encoding alpha1beta-ARs in the pineal gland, with a peak at midnight.

168 xpressed in a rhythmic manner in the chicken pineal gland, with peak levels at early subjective night