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1 anced series of irreversible (2-substituted)-piperidyl-1,2,3-triazole urea inhibitors of ABHD6, inclu
2 tivity relationship (SAR) of (2-substituted)-piperidyl-1,2,3-TUs that selectively inactivate DAGLbeta
3 r development was the 6-chloro-3-(1-propyl-4-piperidyl)-1H-benzimidazol-2-one (19), which displayed t
4 d (P4S), imidazole-4-acetic acid (IAA), 5-(4-piperidyl)-3-isothiazolol (thio-4-PIOL) and 5-(4-piperid
5 uality low-throughput screen identified 5-(4-piperidyl)-3-isoxazolol (4-PIOL) as a potent plasminogen
6 ridyl)-3-isothiazolol (thio-4-PIOL) and 5-(4-piperidyl)-3-isoxazolol (4-PIOL).
7 agonists such as the phencyclidine analogue [piperidyl-3,4-(3)H(N)]-N-[1-(2-thienyl)cyclohexyl]-3,4-p
8 (3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H benzimidazol-2-one] an
9 tor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone (3, K(i) values of 492 a
10 s previously coupled with N-(4-methoxytrityl)piperidyl-4-O-(2-cyanoethyl diisopropylphosphoramidite)
11  aminoboranes, (1-Pip-2-BH2-C6H4)2 (2; Pip = piperidyl) and (1-NEt2-2-BH2-C6H4)2 (3; NEt2 = diethylam
12 d and tested a group of 12 hydroxylated 2-(2-piperidyl)- and 2-(2-pyrrolidyl)chromans.
13                      (R)-N-(2-Fluoroethyl)-3-piperidyl benzilate (3-FEPB, 22, K(i) = 12.1 nM) and N-(
14  22, K(i) = 12.1 nM) and N-(2-fluoroethyl)-4-piperidyl benzilate (4-FEPB, 8, K(i) = 1.83 nM) were sel
15 et rahydrofuran-2-yl]-N-[2-[[1-(2-pyridyl)-4-piperidyl]carbamoylamino]ethyl]purine-2 -carboxamide], o
16         We conclude that modification of the piperidyl fragment of 1 will not lead to more potent ves
17 osed a carbonyl group between the phenyl and piperidyl groups of the prototypical VAChT ligand vesami
18 enyl)amino-2,2-(1-oxyl-2,2,6,6-tetramethyl-4-piperidyl idene)di(oxymethylene)ethyl triphosphate (SSL-
19 an issue with previous series of 2-aryl-3-(4-piperidyl)indoles.
20 electivity of the weak partial agonist, 5-(4-piperidyl)isoxazol-3-ol (4-PIOL), as a potential mechani
21         1,3-Disubstituted ureas possessing a piperidyl moiety have been synthesized to investigate th
22 l regions occur near the hydroxyl oxygen and piperidyl nitrogen atoms.
23  suggest that the mechanism of action of the piperidyl nucleoside phosphoramidates involves the intra
24        A series of 31 compounds based on the piperidyl or pyrrolidyl benzilate scaffold were prepared
25                                              Piperidyl phosphoramidate analogues are also converted t
26              A series of novel haloethyl and piperidyl phosphoramidate FdUMP prodrug analogues has be
27             Activation of the benzotriazolyl piperidyl phosphoramidates is followed by P-N bond hydro
28 chlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidyl)pyrazole-3-carbo xamide].
29 trict the conformation of the appended C(11) piperidyl substituent in an axial orientation.
30 rfuryl phosphoramidates bearing haloethyl or piperidyl substituents was synthesized and used to inves
31 -n,n-Dimethyl-n-(2',2',6', 6'-tetramethyl-4'-piperidyl) (TEMPO-DPPC).
32 h 3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide (AZD7762) did not sens
33 arylpiperidines via the coupling of 4-(N-BOC-piperidyl)zinc iodide with aryl halides and triflates is

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