ライフサイエンスコーパス: piriform

1 Anterior piriform adrenergic blockade prevented acquisition of si

2 habenula, striatum, amygdala, the cingulate, piriform and entorhinal cortex, and in cerebellum, notab

3 Also, the piriform and insular cortices displayed strong PIST labe

4 se to these odors in the olfactory (anterior piriform and orbitofrontal) cortices and emotion-relevan

5 egions (dentate gyrus, hippocampal area CA1, piriform and parietal cortices) at 6 and 12 months of ag

6 s the endopiriform, secondary somatosensory, piriform and prefrontal cortex.

7 Curiously, the piriform and somatosensory cortices were more vulnerable

8 a distributive pattern of projections to the piriform and stereotyped projections to the amygdala pro

9 educed in the hippocampus and somatosensory, piriform, and entorhinal cortices of all three strains o

10 ed BDNF expression in the frontal, parietal, piriform, and entorhinal cortices, increased NT-3 expres

11 emble patterns in perirhinal, orbitofrontal, piriform, and insular cortices.

12 ons as indexed by a reduction in overlap for piriform Arc(+) pyramidal neurons after training.

13 e similar as indexed by increased overlap in piriform Arc-expressing (Arc(+)) pyramidal neurons.

14 clofen, a GABA(B) agonist known to attenuate piriform associative inputs, interfered with within-cate

15 This circuitry may shape the ensembles of piriform cells that encode odorant identity.

16 c and GABAergic neuronal subtypes within the piriform circuits.

17 dal cell connections across the rat anterior piriform cortex (aPC) and found a pronounced gradient of

18 Ensemble activity patterns in anterior piriform cortex (APC) and orbitofrontal cortex (OFC) ref

19 P(+)) cells within the CC, Ctx, and anterior piriform cortex (aPC) and used prelabeling with 5-ethyny

20 Layer 2 principal neurons in the anterior piriform cortex (APC) can be divided into 2 subtypes: se

21 The anterior piriform cortex (APC) has been shown to be an essential

22 NMDA receptor (NMDAR) number in the anterior piriform cortex (aPC) in rat induced by a 10 min pairing

23 he first time that adrenoceptors in anterior piriform cortex (aPC) must be engaged for adult rats to

24 ded neural ensemble activity in the anterior piriform cortex (aPC) of rats performing an odor mixture

25 rivation is in the highly excitable anterior piriform cortex (APC) of the brain.

26 examines synaptic plasticity in the anterior piriform cortex (aPC) using ex vivo slices from rat pups

27 ction to the ventral portion of the anterior piriform cortex (APC) was substantial, while the dorsal

28 f IAA deficiency requires an intact anterior piriform cortex (APC), but does it act alone?

29 specific odorant features, but the anterior piriform cortex (aPCX) and posterior piriform cortex (pP

30 striction, we hypothesized that the anterior piriform cortex (APCx) and the olfactory tubercle (OTu)

31 tion, the analysis of neural circuits in the piriform cortex (PC) demonstrated the importance of not

32 ng from the association fiber (AF) system in piriform cortex (PC) make axodendritic synapses on granu

33 inhibitory and glutamatergic neurons in the piriform cortex (PC) of mice.

34 nic synapses (AASs) in brain slices from the piriform cortex (PC) of mice.

35 n adult rat olfactory bulb (OB) and anterior piriform cortex (PC) were assessed after discrimination

36 ation of cortical association fibers (AF) in piriform cortex (PC).

37 these mitral/tufted cells in turn project to piriform cortex (PC).

38 ral and granular layers of the OB and in the piriform cortex (PC).

39 ct regions: olfactory bulb (OB) and anterior piriform cortex (PC).

40 Hyperactive odor-evoked activity in the piriform cortex (PCX) and increased OB-PCX functional co

41 s, we found that 26% of neurons in the mouse piriform cortex (PCX) display modulation in firing to ca

42 The piriform cortex (PCX) is the largest component of the ol

43 s well as local field potentials in the MDT, piriform cortex (PCX), and OFC in rats performing a two-

44 In the piriform cortex (PCx), spatially dispersed sensory input

45 electrophysiological recordings in anterior piriform cortex (PCx), we assessed how cortical neurons

46 e-associated astrocytes" (SAAs) in posterior piriform cortex (PPC) are unique by virtue of a direct a

47 ributed ensemble activity in human posterior piriform cortex (PPC) coincides with perceptual ratings

48 resentations of the odor target in posterior piriform cortex (PPC) gave way to poststimulus represent

49 Retrograde tracing from the OB or posterior piriform cortex (PPC) showed that the APC projects to th

50 ons positive for GAD65-EGFP in the posterior piriform cortex (PPC).

51 nterior piriform cortex (aPCX) and posterior piriform cortex (pPCX) differ markedly in their anatomic

52 obust interhemispheric asymmetry in anterior piriform cortex activity that emerges during specific st

53 nput from the anterior olfactory nucleus and piriform cortex already by the second week.

54 Pyramidal cells in adult piriform cortex also lack I(h), the mixed Na(+)-K(+) cur

55 of the basal telencephalon, most notably the piriform cortex and amygdala.

56 cross brain regions, and particularly in the piriform cortex and cortical amygdala.

57 dus within 3 h after KA treatment and in the piriform cortex and hippocampus by 6 h after KA.

58 reased theta-specific phase coupling between piriform cortex and hippocampus.

59 us (AON) lies between the olfactory bulb and piriform cortex and is the first bilaterally innervated

60 d with a direct monosynaptic pathway linking piriform cortex and OFC.

61 However, the LEC also projects back to the piriform cortex and olfactory bulb.

62 ible changes in odor-evoked fMRI activity in piriform cortex and orbitofrontal cortex (OFC).

63 ed by learning-induced response increases in piriform cortex and orbitofrontal cortex (OFC).

64 nfection from the olfactory bulb (OB) to the piriform cortex and other areas connected to the OB was

65 ns that resembled neurogliaform cells of the piriform cortex and provided feedforward inhibition of t

66 phe magnus nucleus, and was decreased in the piriform cortex and septum.

67 e, only C. sociabilis had OTR binding in the piriform cortex and thalamus and V1aR binding in the olf

68 idual glomeruli in the olfactory bulb to the piriform cortex and the cortical amygdala.

69 w that spatial ensemble activity patterns in piriform cortex are closely linked to the perceptual mea

70 rceptual codes of odour quality in posterior piriform cortex are degraded in patients with Alzheimer'

71 The orbitofrontal cortex (OFC) and piriform cortex are involved in encoding the predictive

72 lly to reach the ventral pallium deep to the piriform cortex at E14.5 in the mouse.

73 ion-invariant neurons are overrepresented in piriform cortex but not in olfactory bulb mitral and tuf

74 dy further explored LEC feedback to anterior piriform cortex by examining how LEC top-down input modu

75 bitrarily chosen subpopulation of neurons in piriform cortex can elicit different behavioral response

76 Steady-state interhemispheric anterior piriform cortex coherence is reduced during the initial

77 reduced microgliosis in the hippocampus and piriform cortex compared with T2(+/+)PS mice.

78 al stimuli to sensory representations in the piriform cortex during odor-driven social learning.

79 We now report that OPCs in adult murine piriform cortex express low levels of doublecortin, a ma

80 evated baseline, spontaneous activity in the piriform cortex extends the dynamic range of odor repres

81 Together these findings suggest that human piriform cortex has access to olfactory content in the t

82 Cholinergic modulation within the piriform cortex has long been proposed to serve importan

83 To determine whether OPCs in the piriform cortex have inherently different physiological

84 In rats and birds, the anterior piriform cortex houses the detector, but its mechanism h

85 ry formed between the olfactory bulb and the piriform cortex in anesthetized mice.

86 In recordings from anterior piriform cortex in awake behaving mice, we found that ne

87 ur study suggests a causal role of posterior piriform cortex in differentiating olfactory objects.

88 nd olfactory-related oscillations within the piriform cortex in vivo.

89 revious reports, these findings suggest that piriform cortex includes multiple subdivisions, which ma

90 Inactivation of piriform cortex increased odor responsiveness and pairwi

91 assium changes demonstrates that SLEs in the piriform cortex initiate in the superficial layer 1 lack

92 Pyramidal cells in piriform cortex integrate sensory information from multi

93 Finally, post-training disruption of piriform cortex intracortical association fiber synapses

94 An interesting finding is the absence of the piriform cortex involvement in young male rats and the c

95 gamma oscillations in the vStr LFP and that piriform cortex is an important driver of gamma-band osc

96 trated that a reduction in plasticity in the piriform cortex is associated with a selective impairmen

97 cells across major cortical subdivisions of piriform cortex is lacking.

98 These observations demonstrate that the piriform cortex is sufficient to elicit learned behavior

99 d, odor-distinctive patterns of responses in piriform cortex layer 2 principal cells: Approximately 1

100 the peculiar organization of the superficial piriform cortex layers, which are characterized by unmye

101 Both right and left piriform cortex local field potential activities were re

102 oligodendrocytes (OLs), whereas those in the piriform cortex may also generate neurons.

103 activity during slow-wave states within the piriform cortex may be shaped by recent olfactory experi

104 learning until mastery, suggesting that each piriform cortex may contribute something unique to odour

105 The neural circuits of the piriform cortex mediate field potential oscillations and

106 cell fate and later to specify layer II/III piriform cortex neuronal identities.

107 We found that the overall spike rates of piriform cortex neurons (PCNs) were sensitive to the rel

108 Piriform cortex neurons from E14.5 mutant embryos displa

109 n a spatially scattered ensemble of anterior piriform cortex neurons, and the ensemble activity inclu

110 ng how LEC top-down input modulates anterior piriform cortex odor evoked activity in rats.

111 robust odor representations in the anterior piriform cortex of adult rats when odor was associated w

112 However, neurotoxicity in the piriform cortex of immature females treated for 60days a

113 The piriform cortex provides an ideal system to address this

114 However, piriform cortex pyramidal cells also receive dense intra

115 espread and broadly tuned than excitation in piriform cortex pyramidal cells.

116 enhanced intrinsic neuronal excitability of piriform cortex pyramidal neurons, and in their excitato

117 are primarily located in the in the adjacent piriform cortex rather than in the vStr itself, providin

118 ve suggested a model in which neurons of the piriform cortex receive convergent input from random col

119 n to provide direct evidence that neurons in piriform cortex receive convergent synaptic input from d

120 The olfactory bulb (OB) and piriform cortex receive dense cholinergic projections fr

121 to the olfactory bulb, such that concurrent piriform cortex recordings show no evidence of enhanced

122 lt CNS-though rare, neuron production in the piriform cortex remains a possibility.

123 ves dorsal olfactory bulb input, whereas the piriform cortex samples the whole olfactory bulb without

124 Here we used patch-clamp recordings in rat piriform cortex slices to examine cellular mechanisms th

125 onic synapse are significantly higher in the piriform cortex than in the neocortex.

126 tiple relays in a network extending from the piriform cortex through the hippocampus can be different

127 fMRI data for a node within the ipsilateral piriform cortex to be important for seizure modulation i

128 We introduced channelrhodopsin into the piriform cortex to characterize these intrinsic circuits

129 dendrites and that feedback projections from piriform cortex to olfactory bulb interneurons are a sou

130 stablished major neural pathways linking the piriform cortex to other cortical and subcortical region

131 aired single-unit recordings in rat anterior piriform cortex to test several predictions regarding en

132 Notably, the projection to piriform cortex was predominantly from ventrolateral orb

133 hereas cingulate cortex and to a less extent piriform cortex were affected preferentially by the CIV

134 gs from both the olfactory bulb and anterior piriform cortex were performed in freely breathing ureth

135 DCX and PSA-NCAM immunoreactive cells in the piriform cortex were quantified as measures of plasticit

136 put/output curves for two connections in the piriform cortex were similar to those for the LPP, where

137 Odor representations in anterior piriform cortex were sparser than typical in adult rat a

138 I-III of the parietal cortex and superficial piriform cortex were the most sensitive followed by othe

139 o-active neurons that are distributed across piriform cortex without any apparent spatial organizatio

140 a tecta, and anterior olfactory tubercle and piriform cortex) have cells that express either calbindi

141 The analysis was of piriform cortex, a highly epileptogenic area of cerebral

142 We did not observe these effects in anterior piriform cortex, amygdala or orbitofrontal cortex, indic

143 t of local field potential activity in human piriform cortex, amygdala, and hippocampus.

144 c suppression of responses from the amygdalo-piriform cortex, an associative temporal cortical struct

145 The three-layered piriform cortex, an integral part of the olfactory syste

146 ygdala, cingulate cortex, hippocampus (CA1), piriform cortex, and BNST were lower in OVX+E2 females c

147 us at 60 and 120 min following KA and in the piriform cortex, and central nucleus of the amygdala at

148 d with within-category pattern separation in piriform cortex, and the magnitude of this drug-induced

149 ry areas, the anterior olfactory nucleus and piriform cortex, and the olfactory associated orbital an

150 of the forebrain, including medial amygdala, piriform cortex, and ventrolateral septum, showed low c-

151 KCC3a in the hippocampus, choroid plexus and piriform cortex, as well as KCC4 in the choroid plexus a

152 gions, such as the hippocampus, thalamus, or piriform cortex, but not in the cerebellum beginning at

153 s have unique and redundant functions in the piriform cortex, controlling the timing of differentiati

154 e laminin immunoreactivity is present in the piriform cortex, corpus callosum (myelinated tracts) amy

155 In piriform cortex, CRF1 binding increased in females and d

156 glutamatergic pacemaker circuits within the piriform cortex, each of which can initiate waves of act

157 ted olfactory epithelium and OB, but not the piriform cortex, express similar, sustained circadian rh

158 e ipsilateral and contralateral OB, AON, and piriform cortex, few studies have examined this circuitr

159 hat extend, largely undiminished, across the piriform cortex, forming a large excitatory network that

160 icited cross-adapting responses in posterior piriform cortex, in accord with the pattern observed in

161 In the piriform cortex, individual odorants activate a unique e

162 s including the olfactory nuclei, neocortex, piriform cortex, induseum griseum, hippocampus, thalamus

163 ammed spatial relationships may not exist in piriform cortex, making flexible random associations the

164 ssion is seen in anterior olfactory nucleus, piriform cortex, median preoptic nucleus, basolateral am

165 might participate in seizure circuitry: the piriform cortex, olfactory tubercle, nucleus accumbens,

166 tive cell numbers were high in, for example, piriform cortex, paraventricular nucleus, supraoptic nuc

167 Neurons in piriform cortex, responsive to a given odorant, are not

168 DCX and PSA-NCAM immunoreactive cells in the piriform cortex, similar to that previously reported in

169 cus on the hippocampus, somatosensory, paleo/piriform cortex, striatum, and various amygdala nuclei.

170 ositive, we showed that in the motor cortex, piriform cortex, striatum, CA1 region of the hippocampus

171 , known to abolish gamma oscillations in the piriform cortex, strongly reduced vStr gamma power and t

172 the c-Fos protein has been evidenced in the piriform cortex, subiculum, entorhinal and perirhinal co

173 nigra, but was increased bilaterally in the piriform cortex, supraoptic nucleus, central nucleus of

174 However, in piriform cortex, the activity of target neurons increase

175 The AC is composed of axons from the piriform cortex, the anterior olfactory nucleus and the

176 idual recognition, particularly the anterior piriform cortex, the CA1 and CA3 regions of anterior dor

177 riched for oxytocin receptors, including the piriform cortex, the left auditory cortex, and CA2 of th

178 ing channelrhodopsin at multiple loci in the piriform cortex, when paired with reward or shock, elici

179 tern does not appear to be maintained in the piriform cortex, where stimuli appear to be coded in a d

180 ur results indicate a double dissociation in piriform cortex, whereby posterior regions encode qualit

181 nt mice presented a reduced thickness of the piriform cortex, which affected projection neurons in la

182 enerated in the forebrain, especially in the piriform cortex, which is the main target of the olfacto

183 ity of the olfactory cortex, principally the piriform cortex, will be described in the context of how

184 ical loop between the olfactory bulb and the piriform cortex, with cortex explaining incoming activit

185 or stimulation enhanced theta power in human piriform cortex, with robust effects at the level of sin

186 b and in the pyramidal cells of the anterior piriform cortex.

187 ns, and later to layer II/III neurons of the piriform cortex.

188 olinergic modulation of the OB inputs to the piriform cortex.

189 ompared to juvenile rats in both the OFC and piriform cortex.

190 rom several areas, including S1, SR, FM, and piriform cortex.

191 bilateral reversible lesions of the anterior piriform cortex.

192 i.e., the hippocampus, substantia nigra, and piriform cortex.

193 ive input times than neurons in the anterior piriform cortex.

194 (mitral/tufted [MT] cells) projecting to the piriform cortex.

195 t power gradient originating in the adjacent piriform cortex.

196 undant axo-axonic synapses across the entire piriform cortex.

197 operties of these synapses across the entire piriform cortex.

198 in putative centrifugal cells and posterior piriform cortex.

199 al migration and homologous to the mammalian piriform cortex.

200 sentations of odor identity and intensity in piriform cortex.

201 on of odors more similar to that seen in the piriform cortex.

202 y bulbs and higher brain regions such as the piriform cortex.

203 he lateral olfactory tract and the posterior piriform cortex.

204 al glutamatergic neurons within normal adult piriform cortex.

205 iate into pyramidal glutamatergic neurons in piriform cortex.

206 n local field potentials within the anterior piriform cortex.

207 integration and analogous to the vertebrate piriform cortex.

208 ctions with both the olfactory bulb (OB) and piriform cortex.

209 temporal cortices, with no changes noted in piriform cortex.

210 anatomical- and theoretical-based models of piriform cortex.

211 f the pseudorabies virus into the rat OB and piriform cortex.

212 y nucleus, the endopiriform nucleus, and the piriform cortex.

213 ating odor response properties of neurons in piriform cortex.

214 ctively expressed in different layers of the piriform cortex.

215 presentations of odor objects are encoded in piriform cortex.

216 principal excitatory neuron in the anterior piriform cortex.

217 tral/tufted (MT) cells carrying OB output to piriform cortex.

218 t but not the associational afferents of the piriform cortex.

219 ives rich glutamatergic projections from the piriform cortex.

220 odel of cholinergic modulation in the OB and piriform cortex.

221 olfactory tract (lot) guidepost cells in the piriform cortex.

222 maker circuits in the septal nucleus and the piriform cortex.

223 sensory input in the olfactory bulb through piriform cortex/olfactory bulb synaptic interactions.

224 patial order in the bulb is discarded in the piriform cortex; axons from individual glomeruli project

225 essing center for olfactory information, the piriform cortex?

226 and polysynaptically) to primary olfactory (piriform) cortex (PC)-connections that might be hypothes

227 from single neurons in posterior olfactory (piriform) cortex (pPC) of awake rats while presenting ba

228 nctional coupling between OFC and olfactory (piriform) cortex and between vmPFC and amygdala revealed

229 rocessing, the projections to the olfactory (piriform) cortex are more diffuse and show characteristi

230 sured neural responses in primary olfactory (piriform) cortex as subjects smelled pairs of odorants s

231 or representations in the primary olfactory (piriform) cortex depend on excitatory sensory afferents

232 The olfactory (piriform) cortex is thought to generate odour percepts a

233 sensory paleocortex, the primary olfactory (piriform) cortex of mice.

234 orsal (MD) thalamus links primary olfactory (piriform) cortex to olfactory neocortical projection sit

235 distributed in the rodent primary olfactory (piriform) cortex.

236 or representations in rat primary olfactory (piriform) cortex.

237 mble activity patterns in primary olfactory (piriform) cortex.

238 d are highly expressed in primary olfactory (piriform) cortex.

239 ity in the mouse primary olfactory (anterior piriform) cortex.

240 training to test for functional asymmetry in piriform cortical activity during learning.

241 The results demonstrate that piriform cortical activity during slow-wave state is sha

242 The results suggest that piriform cortical activity during slow-wave states is sh

243 Piriform cortical circuits are hypothesized to form perc

244 c and GABAergic neuronal subtypes within the piriform cortical circuits.

245 This piriform cortical ensemble activity predicts olfactory p

246 en overlapping mixtures resulted in impaired piriform cortical ensemble pattern separation (enhanced

247 havioral discrimination ability and enhanced piriform cortical ensemble pattern separation.

248 e results demonstrate transient asymmetry in piriform cortical function during odour discrimination l

249 Single-unit activity of piriform cortical layer II/III neurons was recorded simu

250 LEC reversible lesions enhanced ipsilateral piriform cortical local field potential oscillations dur

251 Proximal synapses arise from piriform cortical neurons and facilitate with paired-pul

252 While lot cells and other piriform cortical neurons share a pallial origin, the fa

253 oked excitatory synaptic transmission in rat piriform cortical neurons.

254 t input from olfactory bulb mitral cells and piriform cortical pyramidal cells and is the gateway for

255 ns of the ipsilateral LEC increased anterior piriform cortical single-unit spontaneous activity.

256 single missing component, whereas olfactory (piriform) cortical neural ensembles perform pattern comp

257 y (coherence) between the bilateral anterior piriform cortices is learning- and context-dependent.

258 onal cortical areas (insular, cingulate, and piriform cortices) and hippocampus proper.

259 ntal cortex than in motor, somatosensory, or piriform cortices, greater in superficial than in deep l

260 C projections to both the olfactory bulb and piriform cortices.

261 rtex and ipsilaterally in the entorhinal and piriform cortices.

262 ant responses in the cortex reveals that the piriform discards spatial segregation as well as chemoto

263 These data imply that the piriform does not use spatial order to map odorant ident

264 trast, olfactory recipient regions including piriform, entorhinal, and orbitofrontal cortex showed th

265 onditioning on the contralateral side of the piriform, entorhinal, perirhinal, and parietal cortices

266 7th (reminder) conditioning sessions for the piriform, entorhinal, perirhinal, and parietal cortices,

267 l increase after the reminder session in the piriform, entorhinal, perirhinal, and parietal cortices,

268 experiments reveal that these layer-specific piriform genes mark different subclasses of neurons, whi

269 ity was detected in cortical areas including piriform, insular, cingulate and somatomotor cortices, t

270 ever, the quantitative properties of diverse piriform interneurons are unknown.

271 d memories, and odour information encoded in piriform is routed to target brain areas involved in mul

272 rongly to the medial frontal polar, anterior piriform, medial and ventral orbital, anterior cingulate

273 t early blood-brain barrier pathology in the piriform network is a sensitive and specific predictor (

274 tion of odor representations in the anterior piriform network suggests that odor objects are widely d

275 In the absence of applied odors, piriform neurons exhibit spontaneous firing at mean rate

276 Activation of a small subpopulation of piriform neurons expressing channelrhodopsin at multiple

277 demonstrate that different subpopulations of piriform neurons expressing ChR2 can be discriminated an

278 as well as excitation, the responsiveness of piriform neurons is at least twofold less sparse than cu

279 Piriform neurons receive convergent excitatory inputs fr

280 m a subpopulation of concentration-invariant piriform neurons.

281 namic changes such as those observed here in piriform odor encoding are at the heart of perceptual le

282 t taste-odor convergence occurs in posterior piriform olfactory cortex and calls for a reformulation

283 es formed by olfactory bulb afferents to the piriform (olfactory) cortex significantly contributes to

284 nnections were studied in slices of anterior piriform (olfactory) cortex, and Schaffer-commissural sy

285 ng synchronizes electrical activity in human piriform (olfactory) cortex, as well as in limbic-relate

286 This information is then transmitted to piriform (olfactory) cortex, via axons of olfactory bulb

287 t odor category codes within the perirhinal, piriform, orbitofrontal, and insular cortices suggests t

288 antly, classification analysis revealed that piriform oscillatory activity conveys olfactory-specific

289 However, it remains unknown if piriform outputs are spatially organized, and if distinc

290 ur category, identity and value are coded in piriform (PC), orbitofrontal (OFC) and ventromedial pref

291 ings indicate that aversive learning induces piriform plasticity with corresponding gains in odor ena

292 served cortical volume in the entorhinal and piriform regions compared with T2(+/+)PS mice.

293 e cell degeneration in the retrosplenial and piriform regions.

294 However, piriform response patterns change substantially over a 1

295 medial prefrontal (mPFC), agranular insular, piriform, retrosplenial, and parahippocampal cortices.

296 erion performance, Arc ensembles in anterior piriform showed enhanced stability for the rewarded odor

297 ls emphasizing the importance of distributed piriform templates for the perceptual reconstruction of

298 monstrate that oxytocin directly impacts the piriform, the olfactory sensory cortex, to mediate socia

299 , only one minor cortical area, the amygdalo-piriform transition area (AmPir), contained neurons upst

300 ndividual glomeruli project diffusely to the piriform without apparent spatial preference.