ライフサイエンスコーパス: pituitary gland

1 neuropeptides from tissue in situ (i.e., rat pituitary gland).

2 y infiltration of T and B lymphocytes in the pituitary gland.

3 cell specification and in the adult anterior pituitary gland.

4 e's pouch to ensure the proper growth of the pituitary gland.

5 n that extends to and activates hGH-N in the pituitary gland.

6 ls, resulting in a greatly enlarged anterior pituitary gland.

7 stic mass involving the anterior lobe of the pituitary gland.

8 ted to Rathke's pouch, the primordium of the pituitary gland.

9 tes the synthesis and release of GH from the pituitary gland.

10 thke's pouch, the progenitor of the anterior pituitary gland.

11 sequenced from the posterior lobe of the rat pituitary gland.

12 al for development of the mammalian anterior pituitary gland.

13 ulate the release of growth hormone from the pituitary gland.

14 and functional patterning of the vertebrate pituitary gland.

15 res via the median eminence to the posterior pituitary gland.

16 ction in IL-6-like material in the posterior pituitary gland.

17 ses through communication with the endocrine pituitary gland.

18 cluding brain, skeletal muscle, and anterior pituitary gland.

19 sively expressed in the developing mammalian pituitary gland.

20 n in the liver, pancreas, heart, joints, and pituitary gland.

21 begin to differentiate within the developing pituitary gland.

22 the hormone-producing cells of the anterior pituitary gland.

23 hat SHH is required for proliferation of the pituitary gland.

24 found to induce the production of GH by the pituitary gland.

25 eatic neuroendocrine cells, and the anterior pituitary gland.

26 beta subunit (LHbeta) gene expression in the pituitary gland.

27 vere defects of the limbs, lung and anterior pituitary gland.

28 data suggest that the tumors arise from the pituitary gland.

29 same cells that contained DARPP-32-IR in the pituitary gland.

30 ng a loxP-modified SF1 locus in the anterior pituitary gland.

31 ncludes the thyrotrope cells of the anterior pituitary gland.

32 salivary gland, mammary gland, stomach, and pituitary gland.

33 ion of autoreactive T and B cells within the pituitary gland.

34 red for angiogenesis in the developing mouse pituitary gland.

35 thke's pouch, the primordium of the anterior pituitary gland.

36 ss elevated levels of CRH-BP in the anterior pituitary gland.

37 moderate levels in spinal cord, stomach, and pituitary gland.

38 growth hormone release from the rat anterior pituitary gland.

39 s to be present specifically in the anterior pituitary gland.

40 endocrine regulation since it innervates the pituitary gland.

41 ited to the thyrotrope cells of the anterior pituitary gland.

42 eloping and mature nervous system and in the pituitary gland.

43 including development of the brain, eyes and pituitary gland.

44 A axis, with the requirement of a functional pituitary gland.

45 ed its exclusive expression in the brain and pituitary gland.

46 marily centrally rather than at the anterior pituitary gland.

47 ge in the number of gonadotrope cells in the pituitary gland.

48 ted whether kisspeptins are expressed in the pituitary gland.

49 rgeted ablation of Jnk genes in the anterior pituitary gland.

50 ther T lymphocytes undergo activation in the pituitary gland.

51 f the anterior and intermediate lobes of the pituitary gland.

52 ing gonadotropin secretion from the anterior pituitary gland.

53 y differentiated endocrine cell types of the pituitary gland.

54 vate the promoters of genes expressed in the pituitary gland.

55 ifferentiate into the endocrine cells of the pituitary gland.

56 lipid rafts was also observed in whole mouse pituitary glands.

57 No OFQ was observed in the pineal or pituitary glands.

58 ells, and the pancreas and submandibular and pituitary glands.

59 37 surgical pituitary adenomas and 11 normal pituitary glands.

60 oteins (TDP-43, FUS, and ubiquilin) in human pituitary glands.

61 I 0.4-1.6]; mean dose 0.53 Gy [SD 1.40]) and pituitary gland (17 [3%] of 510, 1.1 [0.5-2.4] for more

62 (TSHbeta) in the pars tuberalis (PT) of the pituitary gland [2-4].

63 ioma, Rathke's cleft cyst, ectopic posterior pituitary gland), 5.melanin (metastatic melanoma), 6.les

64 g from the pars tuberalis (PT) region of the pituitary gland, a well-defined melatonin target site, c

65 ation that hormones produced in the anterior pituitary gland act as positive regulators of primary B

66 The anterior pituitary gland (adenohypophysis) comprises anterior and

67 e regulators of prolactin secretion from the pituitary gland, also release GABA within the hypothalam

68 with a pronounced hypoplasia of the anterior pituitary gland and a marked decrease in pituitary and s

69 n radiation doses to the gonads, uterus, and pituitary gland and administered chemotherapy were quant

70 cretory granule content proteins of anterior pituitary gland and adrenal medulla.

71 n the control of developmental events in the pituitary gland and assign a critical role for hypothala

72 adrenomedullin (AM), is present in brain and pituitary gland and binds to the same receptors as AM an

73 one secretagogue receptor (GHS-R) from human pituitary gland and brain identified a third G protein-c

74 well as real data obtained from mouse liver, pituitary gland and data from NIH3T3, U2OS cell lines.

75 beta locus is readily detectable only in the pituitary gland and derived cell sources such as GH3 som

76 ell as expression in the developing anterior pituitary gland and first branchial arch.

77 and specific cell phenotypes in the anterior pituitary gland and in several other organs.

78 n (PRL)-producing lactotroph of the anterior pituitary gland and induce development of PRL-producing

79 denosine has been identified in the anterior pituitary gland and is secreted from cultured folliculos

80 signals that induce, pattern and specify the pituitary gland and its cell types.

81 tribution throughout the mammalian brain and pituitary gland and mediates a number of physiological f

82 ium is usually due to tumors in the anterior pituitary gland and occurs occasionally in hereditary mu

83 polypeptide hormone produced by the anterior pituitary gland and other sites that acts both systemica

84 receptors, each of which is expressed in the pituitary gland and other tissues.

85 e (eLH/CGbeta) that (1) is expressed in both pituitary gland and placenta, (2) encodes a characterist

86 locus in B cells distinct from those in the pituitary gland and placenta.

87 recently discovered protein, produced by the pituitary gland and secreted into the bloodstream.

88 acterized neurosecretory structures, the rat pituitary gland and single cultured Aplysia bag cell neu

89 red for correct development of the mammalian pituitary gland and spinal motoneurons.

90 nRH include the gonadotropes of the anterior pituitary gland and the cells of various hormone-depende

91 is activity through negative feedback to the pituitary gland and the central nervous system (CNS).

92 rticotropin-releasing factor in the anterior pituitary gland and the central nervous system.

93 owth hormone secretagogues (GHSs) act on the pituitary gland and the hypothalamus to stimulate and am

94 the determination and differentiation of the pituitary gland and the ventral hypothalamus.

95 ination and proliferation events of anterior pituitary gland and tooth organogenesis.

96 (AH) is a rare inflammatory condition of the pituitary gland and usually affects women of childbearin

97 abnormalities in the developing hyoid bone, pituitary gland and vomeronasal organ.

98 , GHRH-R mRNA was analyzed in 2 normal human pituitary glands and 16 human pituitary adenomas using i

99 n (MALDI) MSI six nonpathological (NP) human pituitary glands and 45 hormone secreting and nonsecreti

100 and castrated rats without anterior or whole pituitary glands and were processed for histology and im

101 delta is highly expressed in salivary gland, pituitary gland, and adrenal gland, whereas p38alpha is

102 e, and in the rat is expressed in the brain, pituitary gland, and brown adipose tissue (BAT).

103 genitourinary tracts, developing cartilage, pituitary gland, and discrete regions of the central and

104 adult brain with a high concentration in the pituitary gland, and expression of Wnt10b was highest in

105 in target tissues e.g.: uterus, breast, and pituitary gland, and hormone-responsive tumors occur at

106 expresses in certain tissues, including the pituitary gland, and negatively regulates the LHbeta gen

107 on doses to the testes, ovaries, uterus, and pituitary gland, and related these to the risk of stillb

108 signaling in the formation of the vertebrate pituitary gland, and suggest that Hh signaling from neur

109 1)C-dihydroergotamine in the choroid plexus, pituitary gland, and venous sinuses as expected from the

110 d by a 50% threshold for all lesions and the pituitary gland; and for (18)F-FDG (C)-RD of SUVs of the

111 Subsequently, the anterior pituitary gland appears bifurcated, dysmorphic and occas

112 Prodynorphin (ProDYN) in the anterior pituitary gland appears to be processed differently from

113 ylamide gels, the soluble enzyme from bovine pituitary glands appears as two bands of 170 and 135 kDa

114 The intermediate and anterior lobes of the pituitary gland are derived from an invagination of oral

115 The anterior and intermediate lobes of the pituitary gland are formed from Rathke's pouch.

116 lts suggest that the actions of ANXA1 in the pituitary gland are independent of Fpr1 but may involve

117 otrophs and other cell types of the anterior pituitary gland are not well understood at present.

118 pulsatile release of gonadotropins from the pituitary gland are unknown.

119 required for the development of the anterior pituitary gland, are the predominant cause of MPHD (mult

120 Using the mouse pituitary gland as a model, the extraction protocol effe

121 cuate nucleus of the hypothalamus and in the pituitary gland as a model, we established a unique prot

122 s in up-regulation of both p53 and GH in the pituitary gland, as well as increased GH expression in n

123 r mechanisms underlying the formation of the pituitary gland, as well as the initial development of o

124 is not expressed in Rathke's pouch or in the pituitary gland at any time of embryogenesis.

125 ith a complete absence of vasculature in the pituitary gland at birth.

126 ts reveals that the dorsoventral axis of the pituitary gland becomes ventralized, with dorsal extensi

127 ated by the pars tuberalis (PT) of the fetal pituitary gland, before the fetal circadian system and a

128 The pineal and pituitary glands both expressed rhythms that persisted f

129 ne with mild lymphocytic infiltration in the pituitary gland but no clinical signs of hypophysitis, a

130 is expressed in the developing forebrain and pituitary gland, but its role during hypothalamo-pituita

131 low levels in several brain regions and the pituitary gland, but not in several peripheral tissues e

132 d1, is not expressed in the developing mouse pituitary gland, but rather in the mesenchyme surroundin

133 ow levels were also detected in the anterior pituitary gland by radioimmunoassay.

134 at adenosine, formed locally in the anterior pituitary gland can stimulate gap junction communication

135 Resection of the pituitary gland causes iatrogenic hypopituitarism which

136 pituitary development, we screened an adult pituitary gland cDNA library for homeobox sequences.

137 eus (SCN) and the pars tuberalis (PT) of the pituitary gland, collected every 4 h throughout 24 h, fr

138 only in the rostral ventral diencephalon and pituitary gland, commencing on e11.5, marks pituitary ce

139 , is essential for normal development of the pituitary gland, craniofacial region, eyes, heart, abdom

140 Null homozygotes exhibit arrest of pituitary gland development at the committed Rathke pouc

141 tein SC35 controls cell proliferation during pituitary gland development but is completely dispensabl

142 Pituitary gland development serves as an excellent model

143 During mammalian pituitary gland development, distinct cell types emerge

144 proliferation and cell-type determination in pituitary gland development.

145 meobox genes Rpx, Lhx3 and Pit1 for anterior pituitary gland development.

146 hine on the levels of dynorphin(1-13) in the pituitary gland, different brain regions, spinal cord an

147 During the development of the pituitary gland, distinct hormone-producing cell types a

148 box gene Six3 is expressed in the developing pituitary gland during mouse development but its functio

149 al ectoderm exhibit craniofacial defects and pituitary gland dysmorphology, but normal pituitary cell

150 n the rat, prolactin (PRL) from the anterior pituitary gland exerts its luteotropic function on the o

151 Pttg(-/-) pituitary glands exhibit ARF/p53/p21-dependent senescenc

152 racterize FSH glycosylation, FSH isoforms in pituitary gland extracts and a variety of physiological

153 x2 is expressed in both developing and adult pituitary gland, eye and brain tissues, suggesting an im

154 levels of thyroid-stimulating hormone in the pituitary gland), features found in Hashimoto's thyroidi

155 odomain transcription factor is critical for pituitary gland formation and specification of the anter

156 has been proved to be essential for initial pituitary gland formation.

157 our FPR family members in the mouse anterior pituitary gland, Fpr-rs1, Fpr-rs2, Fpr-rs6, and Fpr-rs7.

158 We also analysed pituitary glands from individuals with Abeta pathology a

159 n, required to prevent induction of multiple pituitary glands from oral ectoderm.

160 nucleus of the hypothalamus (PVH) regulates pituitary gland function and feeding, and innervates aut

161 fied included genes involved in hypothalamic-pituitary gland functions.

162 In the pituitary gland, GLAST is likely expressed by folliculo-

163 art because no pathologic examination of the pituitary gland has been reported to date.

164 After embolization therapy, pituitary gland height decreased and signal intensity vo

165 In the developing pituitary gland, Hlf was highly expressed in the rostral

166 while the circulating concentrations of the pituitary gland hormones vasopressin and adrenocorticotr

167 nt decrease in dynorphin(1-13) levels in the pituitary gland, hypothalamus, hippocampus, striatum, ce

168 protein and localized a specific area of the pituitary gland (i.e., adenohypophysis) known to secrete

169 ous syt isoforms are highly expressed in the pituitary gland in a lobe, and sex-specific manner.

170 revealed that myosin XV is expressed in the pituitary gland in both humans and mice.

171 yonic development of the hypothalamus and/or pituitary gland in humans results in congenital hypopitu

172 esions located in cerebellar hemispheres and pituitary gland in just one patient.

173 uterotonic agent known, is released from the pituitary gland in large amounts during parturition in a

174 M homeobox genes, determine formation of the pituitary gland in mice.

175 rise from the intermediate lobe cells of the pituitary gland in p27-/- mice, as well as in Rb+/- mice

176 nstrated it to be released from the anterior pituitary gland in vivo.

177 sent an expression profile of the developing pituitary gland including 83 transcripts, 40% of which a

178 ergic neurons and the vascular supply of the pituitary gland intact.

179 The anterior pituitary gland integrates the repertoire of hormonal si

180 suggest that serotonin plays a role in SENC/pituitary gland interaction.

181 ocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption

182 The mammalian anterior pituitary gland is a compound endocrine organ that regul

183 The vertebrate pituitary gland is a key endocrine control organ that co

184 the dense cores of secretory granules of the pituitary gland is a Lubrol-insoluble aggregate.

185 The pituitary gland is an endocrine organ that is developmen

186 The anterior lobe of the pituitary gland is composed of five hormone-producing ce

187 dural AV fistula in the cavernous sinus, the pituitary gland is enlarged, which should not be misdiag

188 nt understanding of the role of PROP1 in the pituitary gland is limited to the repression and activat

189 fact that in the Six3-deficient embryos the pituitary gland is not induced.

190 The pituitary gland is particularly sensitive to genetic alt

191 tin (PRL) from the anterior lobe (AL) of the pituitary gland is tonically inhibited by dopamine (DA)

192 The pituitary gland is unique to Chordates, with significant

193 y, the broad physiological importance of the pituitary gland, its intriguing organogenesis, and the c

194 ere injected together there was no effect on pituitary gland, kidneys and spleen.

195 ayer of the cerebellum, and rostral anterior pituitary gland (location of corticotropes).

196 in effective imaging of the adrenal glands, pituitary gland, lymph nodes, pancreas, and thyroid and

197 t melatonin-receptor-containing cells in the pituitary gland may operate as key calendar cells, trans

198 on of these factors to tanycytes but not the pituitary gland, may explain the heterogeneous response

199 s obtained in vitro (binding affinity to rat pituitary gland membranes) and in vivo (rat antiovulator

200 by various immune cells and by the anterior pituitary gland, MIF plays a critical role in the system

201 n, expression of p8 mRNA in developing mouse pituitary glands mirrored its expression in the gonadotr

202 been shown to be secreted from the anterior pituitary gland, monocytes/macrophages, and T cells acti

203 rve sheath, optic disc, posterior globe, and pituitary gland morphology was performed and correlated

204 he endocrine system via the hypothalamus and pituitary gland, neuroendocrinology has evolved into a s

205 Total RNA isolated from the pituitary gland of a female white rhino was used as temp

206 ian eminence (ME) and various regions of the pituitary gland of OVX and OVX+NIL-D rats were measured

207 minergic neurons in the hypothalamus and the pituitary gland of the domestic pig, Sus scrofa, an anim

208 g evolution as SIX3 is also expressed in the pituitary gland of the human embryo.

209 e (LH) beta subunit gene is expressed in the pituitary glands of all mammals, whereas the closely rel

210 L), but not growth hormone, was lower in the pituitary glands of mice with defective mammary gland de

211 In contrast, p8 mRNA was undetectable in the pituitary glands of normal adults.

212 We analyzed at autopsy the pituitary glands of six cancer patients treated with CTL

213 ly, reduced growth hormone expression in the pituitary glands of these mice.

214 Within the pituitary gland, only tyrosine hydroxylase fibers, and n

215 The endocrine-secreting lobe of the pituitary gland, or adenohypophysis, forms from cells at

216 The mammalian pituitary gland originates from two separate germinal ti

217 tg(-/-)p21(-/-) relative to Rb(+/-)Pttg(-/-) pituitary glands, p21-dependent senescence provoked by P

218 zation of contrast agents in the adrenal and pituitary glands, pancreas, and lymph nodes with depende

219 ligands for a receptor found in abundance in pituitary gland, play a broader role in brain function a

220 s involved in AVP release from the posterior pituitary gland, plays a role in the hypertension in RA+

221 cal defect in which the anterior lobe of the pituitary gland protrudes through the cartilage plate th

222 The pituitary gland regulates numerous physiological functio

223 Cushing disease is a condition in which the pituitary gland releases excessive adrenocorticotropic h

224 of the vertebrate neuroendocrine system, the pituitary gland relies on the progressive and coordinate

225 Normal development of the pituitary gland requires coordination between the mainte

226 Within the anterior pituitary gland, RXRgamma expression is limited primaril

227 nificantly reduced body weights and anterior pituitary gland sizes.

228 During development of the mammalian pituitary gland specific hormone-producing cell types, c

229 The pituitary gland, spleen, and thymus are disproportionate

230 at staining was consistently observed in the pituitary glands, stomach, and intestines, and to a less

231 galactosidase was enhanced in Pttg-deficient pituitary glands, telomere lengths were increased.

232 s a peptide hormone produced by the anterior pituitary gland that is critical in lactation.

233 timulate the release of GH from the anterior pituitary gland through the activation of a novel G-prot

234 growth hormone secretagogue receptor in the pituitary gland, thus fulfilling criteria of a brain-gut

235 gulator of developmental angiogenesis in the pituitary gland, thus providing insight into the long-st

236 at determine the tumorigenic response of the pituitary gland to estrogens.

237 y is indicative of a failure of the anterior pituitary gland to stimulate the target endocrine organs

238 We report a catalog of the mouse embryonic pituitary gland transcriptome consisting of five cDNA li

239 A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, a

240 Patients with craniopharyngeoma or a pituitary gland tumor were excluded.

241 During the development of the pituitary gland, two highly related paired-like homeodom

242 n of the hormone-secreting cell types of the pituitary gland underlie severe forms of CPHD.

243 SHH) in outgrowth and differentiation of the pituitary gland using loss- and gain-of-function studies

244 nctional pituitary adenomas and eight normal pituitary glands, using 33 oligonucleotide GeneChip micr

245 araventricular nucleus [PVN]) but not in the pituitary gland, ventromedial hypothalamus, dorsal hippo

246 The mean height of the pituitary gland was 9.4 mm +/- 1.5 (standard deviation)

247 The superior contour of the pituitary gland was convex or flat in group 1 and flat o

248 A growth-promoting principle of the pituitary gland was discovered in 1921, and bovine growt

249 des, significant radioactivity uptake in the pituitary gland was observed (SUV of 0.7 at 30 min pi).

250 of ProDYN in both the anterior and posterior pituitary glands was much lower than that in the neural

251 ) release from the hypothalamus and anterior pituitary gland, we hypothesized that it also might rele

252 termediate (IL) and neural (NL) lobes of the pituitary gland were determined by HPLC-EC.

253 termediate (IL) and neural (NL) lobes of the pituitary gland were dissected and the concentration of

254 The weight of both thyroid and pituitary glands were significantly less in hypothyroid

255 y unique, actions also occur in the anterior pituitary gland where both peptides inhibit adrenocortic

256 iating ANXA1 actions, we have focused on the pituitary gland, where ANXA1 has a well-defined role as

257 s including adrenal gland, kidney, brain and pituitary gland, where it acts to modify sodium homeosta

258 ly innervating different brain areas and the pituitary gland, which could represent an important fact

259 but rather in the mesenchyme surrounding the pituitary gland, which is an essential source of signali

260 of plasma growth hormone (GH) release by the pituitary gland, which shows significant sex differences

261 mation and maturation of blood cells, in the pituitary gland (Wnt10a), and in the face, limbs and ski