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1 the placebo group (P<0.001 for each dose vs. placebo).
2 8 patients (30%) died (78 azithromycin vs 60 placebo).
3 , while AE incidence at 20 ng was similar to placebo.
4 ala and fronto-limbic regions, compared with placebo.
5 igned to escitalopram, 94 to tDCS, and 60 to placebo.
6 de 400 mug (those aged <11 years 200 mug) or placebo.
7 and caudate nucleus iron content compared to placebo.
8 ed to mepolizumab 100 mg and 277 assigned to placebo.
9 progression of diabetic kidney disease than placebo.
10 volume in 1 second (FEV1), as compared with placebo.
11 e dose of MABp1 and 102 at least one dose of placebo.
12 MET; 2) FDIS+placebo; 3) SRP+MET; and 4) SRP+placebo.
13 ril, 31 received bisoprolol, and 30 received placebo.
14 imary end points than did those who received placebo.
15 coconjugates (serotypes Ia, Ib, and III), or placebo.
16 ifference in efficacy between treatments and placebo.
17 ociated with higher adverse event rates than placebo.
18 an 4 times as high with benralizumab as with placebo.
19 s of age compared with children treated with placebo.
20 ear of oral neratinib 240 mg/day or matching placebo.
21 , 30 and 60 mg/kg per infusion) of TNT009 or placebo.
22 ules, the 50-mug patch was not compared with placebo.
23 ere more frequent with tofacitinib than with placebo.
24 amin E, selenium, vitamin E and selenium, or placebo.
25 relapse was lower with lisdexamfetamine than placebo.
26 ts were randomized to tolvaptan 30 mg/day or placebo.
27 <0.0001) for lumacaftor and ivacaftor versus placebo.
28 type 2 diabetes mellitus to canagliflozin or placebo.
29 lihood of response to MEDI2070 compared with placebo.
30 relapse rates in patients given SCIg versus placebo.
31 y and a greater improvement in symptoms than placebo.
32 egimen, and eight (29%) of 28 patients given placebo.
33 es of dofetilide, quinidine, ranolazine, and placebo.
34 vention were randomized to ranolazine versus placebo.
35 125 patients, 62 with eculizumab and 63 with placebo.
36 ea was more common with pertuzumab than with placebo.
37 CS plus escitalopram, or sham tDCS plus oral placebo.
39 e treatment with perindopril, bisoprolol, or placebo (1:1:1) for the duration of trastuzumab adjuvant
41 .5 mug) or 2.5 mug (2 puffs of 1.25 mug), or placebo (2 puffs), administered through the Respimat dev
42 reduce BMI z score to a greater extent than placebo (-3.4%; P = 0.09) and a significant -3.8% reduct
44 %]) than with TMP-SMX (29 of 261 [11.1%]) or placebo (32 of 255 [12.5%]); all adverse events resolved
46 event occurred for 182 patients assigned to placebo [62%, including early escape patients switched t
48 DG and overall composite score compared with placebo, accelerated GE, and was generally safe and well
49 pared with a decrease from 14.9 to 14.1 with placebo (adjusted median difference between the cannabid
50 After short-term treatment at week 12, the placebo-adjusted geometric mean ratio of UACR change fro
52 (Alliance) 100104 study, lenalidomide versus placebo after autologous stem-cell transplantation (ASCT
53 randomly assigned one to one to lapatinib or placebo after completion of first-line/initial chemother
55 a 3:1 ratio to receive 1200 million cells or placebo and assessed for safety through the first 7 days
57 M-CSF alone improves 6-minute walk more than placebo and whether exercise improves 6-minute walk more
58 4.5% from baseline, P<0.01 for all doses vs. placebo) and in levels of triglycerides (reductions of 3
59 the placebo group (P<0.001 for each dose vs. placebo), and everyday-activities scores improved by 5.5
60 received tofacitinib and in one who received placebo, and adjudicated cardiovascular events occurred
62 patients with type 2 diabetes compared with placebo, and showed a similar safety profile to currentl
63 g single crypts were laser microdissected in placebo- and sulindac- treated FAP patient tissue after
65 eceived tofacitinib and in none who received placebo; as compared with placebo, tofacitinib was assoc
66 ive standards on average at baseline, a mean placebo-associated improvement of less than 0.2 SD provi
70 l lenalidomide (2.5 mg/day) or matching oral placebo capsules (2.5 mg/day) for 28-day cycles, until d
72 combined with a 26-week prednisone taper, or placebo combined with a prednisone taper over a period o
74 atients; a phase 3 randomized, double blind, placebo controlled study involving 186 patients; an open
77 deshi children from 2 previous double-blind, placebo-controlled cluster-randomized trials were revisi
78 igator-initiated, multicenter, single-blind, placebo-controlled crossover clinical trial was conducte
79 nce imaging (fMRI) in a 2-drug, double-blind placebo-controlled crossover design conducted from Janua
82 eanut sensitivity and positive double-blind, placebo-controlled food challenges to an eliciting dose
84 underwent a further double-blind crossover, placebo-controlled oral gluten challenge, which had a fi
88 s, and carried out a double-blind randomized placebo-controlled study for 16 weeks, followed by an op
89 this multicenter, double-blind, randomized, placebo-controlled study, 74 participants with peanut al
93 ODS AND TIME was a randomized, double-blind, placebo-controlled trial comparing 150 million bone marr
94 h Malaria) was a randomized, double-blinded, placebo-controlled trial conducted in malaria-endemic Ug
95 was a multicentre, double-blind, randomised placebo-controlled trial for which patients were recruit
96 nducted a phase 2, randomized, double-blind, placebo-controlled trial in 27 centers across North Amer
97 THOD: This 6-week, randomized, double-blind, placebo-controlled trial included patients with schizoph
98 a double-blind, randomized, parallel-group, placebo-controlled trial of a single ketamine infusion (
100 Patients and Methods In this double-blinded, placebo-controlled trial, patients with HER2-positive ea
101 this multicenter, double-blind, randomized, placebo-controlled trial, we assessed the efficacy and s
106 We report two double-blind, randomised, placebo-controlled trials in adults with chronic non-can
107 found in all four much smaller, randomized, placebo-controlled trials specifically designed to evalu
108 vidence from 28 trials (only 3 of which were placebo-controlled) shows that colchicine, nonsteroidal
109 agnetic resonance imaging in a double-blind, placebo-controlled, crossover design to determine how in
110 nducted a phase I, randomized, double-blind, placebo-controlled, dose-escalating study of BMS-936559,
111 We did a phase 2, randomised, double-blind, placebo-controlled, dose-escalation trial of intravenous
114 ducted a phase 2, multicenter, double-blind, placebo-controlled, multiple-ascending-dose trial of inc
115 this randomised, double-blind, multicentre, placebo-controlled, non-inferiority trial, HIV-1-infecte
118 this multicenter, randomized, double-blind, placebo-controlled, parallel-group trial, 93 EoE patient
120 In this 1-year, randomised, double-blinded, placebo-controlled, phase 3 study (LIBERTY AD CHRONOS),
122 is a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial done in 97 centres in
127 This phase 2, randomised, double-blind, placebo-controlled, single-centre, crossover trial asses
129 or 12 weeks, then three rounds of 8 weeks of placebo daily followed by 12 weeks of 150 mg vismodegib
130 or 24 weeks, then three rounds of 8 weeks of placebo daily followed by 8 weeks of 150 mg vismodegib d
131 ell activation, to a greater extent than did placebo (decrease of 2.02+/-2.32 vs. 0.56+/-1.39 ng per
132 gle dose of oral dexamethasone compared with placebo did not increase the proportion of patients with
133 s110402 found that response to GSK561679 and placebo did not significantly differ by genotype alone.
136 k of efficacy could be due to a considerable placebo effect; insensitivity of scales to quantify stif
139 ived rifampicin versus 71 (18%) who received placebo experienced treatment failure or disease recurre
140 atin plus nintedanib (200 mg twice daily) or placebo followed by nintedanib plus placebo monotherapy
141 speridone for 16 weeks followed by switch to placebo for 16 weeks, or to receive placebo for 32 weeks
145 orally twice daily) for 90 days followed by placebo for 60 days (group 1), or placebo for 90 days fo
146 ollowed by placebo for 60 days (group 1), or placebo for 90 days followed by clemastine fumarate (5.3
147 study, risankizumab was more effective than placebo for inducing clinical remission in patients with
148 d directional favorability of tolvaptan over placebo for the primary endpoint compared with patients
150 ive aspirin, at a dose of 150 mg per day, or placebo from 11 to 14 weeks of gestation until 36 weeks
152 i was noted in the vaccine compared with the placebo group (0.149 mean episodes vs 0.146 mean episode
153 ere similar in the liraglutide group and the placebo group (15.1 events and 16.5 events per 1000 pati
155 he prednisolone group and 2.16 points in the placebo group (adjusted difference, -0.20; 95% CI, -0.40
156 min D3 + calcium group and 64 (5.58%) in the placebo group (difference, 1.69% [95% CI, -0.06% to 3.46
157 ed in the idelalisib group compared with the placebo group (grade >/=3 infections and infestations: 8
158 group and in 85 of 158 patients (54%) in the placebo group (hazard ratio, 0.78; 95% CI, 0.57 to 1.07;
159 .2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interv
160 sib group versus 4.0 months (3.1-5.2) in the placebo group (HR 0.76 [0.60-0.97], one-sided p=0.014).
162 ectively, as compared with 2.4 points in the placebo group (P<0.001 for each dose vs. placebo), and e
164 cid group and in 2.8% of the patients in the placebo group (P=0.001), and seizures occurred in 0.7% a
166 ypothyroid Symptoms score (0.2+/-15.3 in the placebo group and 0.2+/-14.4 in the levothyroxine group;
169 ance was slowed 4 hours postchallenge in the placebo group but not in the gammaT treatment group.
171 roup, 3 in the high-dose group, and 1 in the placebo group discontinued the trial regimen because of
173 erence between the cannabidiol group and the placebo group in change in seizure frequency, -22.8 perc
174 rence between the levosimendan group and the placebo group in rates of hypotension or cardiac arrhyth
176 k 6 in the 80 mg/day group compared with the placebo group on the Abnormal Involuntary Movement Scale
177 s, improvement persisted in 1 patient in the placebo group versus 3 of 4 in the rituximab group, wher
178 trimethoprim-sulfamethoxazole group and the placebo group was similar (mean [SD] change in weight-fo
179 raglutide group versus 46 (6%) of 738 in the placebo group were diagnosed with diabetes while on trea
180 ndetanib group) or placebo plus gemcitabine (placebo group) according to pre-generated sequences prod
182 arib group vs two [2%] of 99 patients in the placebo group), fatigue or asthenia (eight [4%] vs two [
183 the masitinib group vs one [2%] of 63 in the placebo group), rash (four [6%] vs none), and asthenia (
186 l, we randomly allocated 172 57 (33%) to the placebo group, 57 (33%) to the low-dose group, and 58 (3
189 as 27% lower in the active group than in the placebo group, but this did not reach significance (esti
190 ious adverse events: one (2%) patient in the placebo group, three (5%) in the low-dose group, and two
202 score, 0 in the sertraline group vs 0 in the placebo group; between-group difference, 0 [95% CI, -10.
204 parlisib group versus 23 (16%) of 140 in the placebo group; the most frequent serious adverse events
205 1 year were similar between the ramipril and placebo groups (162.1 +/- 70.5 mm(3) vs. 177.3 +/- 94.3
207 abnormalities between the PfSPZ Vaccine and placebo groups, and only grade 1 (mild) local or systemi
209 ff, 104 patients (22%; 54 azithromycin vs 50 placebo) had experienced an airflow decline; 138 patient
210 ared pain modulation through treatment cues (placebo hypoalgesia, treatment context) with pain modula
212 million bone marrow mononuclear cells versus placebo in 120 patients with anterior ST-segment-elevati
213 was a randomized trial of evolocumab versus placebo in 27 564 patients with atherosclerotic disease
214 least squares mean difference compared with placebo in absolute change in ppFEV1 from all on-treatme
220 crease of 3.8%) compared with children given placebo (increase of 0.5%, increase of 0.05%, and decrea
221 l injection of gentamicin solution (8 mg) or placebo into 2 intact skin sites for 2 days in 4 of 5 pa
222 on in exacerbations with FF/VI compared with placebo, irrespective of a history of exacerbations or b
223 mine if testosterone treatment compared with placebo is associated with improved verbal memory and ot
227 with the last month of leuprolide alone, the placebo month, and the second and third months of estrad
229 y subcutaneous anakinra, 100 mg (n = 25), or placebo (n = 25) for 4 weeks and were followed for an ad
230 allergy (ages 4-25 years) were treated with placebo (n = 25), Viaskin Peanut 100 mug (VP100; n = 24)
232 ned to either the interventional (n = 48) or placebo (n = 49) group; 9 infants were exclusively breas
236 e of three groups in blocks of 15 to receive placebo (normal saline), low-dose ketamine (0.5 mg/kg),
237 quency was 43% with cannabidiol and 27% with placebo (odds ratio, 2.00; 95% CI, 0.93 to 4.30; P=0.08)
238 oic acid), the multidomain intervention plus placebo, omega 3 polyunsaturated fatty acids alone, or p
239 or Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis In Myoca
240 e the effect of subcutaneous anakinra versus placebo on fatigue severity in female patients with CFS.
241 tly greater reduction in anxiety relative to placebo on the LSAS (Time x Treatment: F9,115=2.6, p=0.0
242 , rivaroxaban twice a day (5 mg with aspirin placebo once a day), or to aspirin once a day (100 mg an
243 oral cabotegravir 30 mg tablets or matching placebo once daily during a 4 week oral lead-in phase, f
244 =2.0) were assigned randomly to groups given placebo or 100, 300, 450, 600, or 900 mg latiglutenase d
246 , patients were randomly assigned to receive placebo or hydrocortisone (0.5 mg/kg twice per day for 7
247 to receive 12 weeks of blind treatment with placebo or MABp1, a true human antibody targeting IL-1al
248 of invasive fungal infections compared with placebo or no intervention in critically ill patients wi
249 e lenalidomide group and 23.5 months for the placebo or observation group (hazard ratio, 0.48; 95% CI
252 n with a history of myocardial infarction to placebo or one of three doses of canakinumab (50 mg, 150
253 in two randomized treatment periods of daily placebo or PF-04958242 for 5 days separated by a washout
254 l significance of the study drug compared to placebo ( P < 0.0161 and P < 0.0001, respectively).
255 nide (0 [range, 0-2] vs 2.5 [range, 0-4] for placebo; P < .01), with complete suppression observed in
257 randomized to 21 mg nicotine (TNP; n=37) or placebo (PBO; n=43) transdermal patch following overnigh
258 allocated ramucirumab plus docetaxel versus placebo plus docetaxel (median 4.07 months [95% CI 2.96-
259 tanib plus gemcitabine (vandetanib group) or placebo plus gemcitabine (placebo group) according to pr
261 costeroids vs 12% [39 patients] who received placebo plus topical corticosteroids; p<0.0001) and EASI
262 -line oral buparlisib (100 mg once daily) or placebo, plus intravenous paclitaxel (80 mg/m(2) on days
263 us injection of either mepolizumab 100 mg or placebo, plus standard of care, every 4 weeks for 24 wee
268 genetic sequence of viruses from vaccine and placebo recipients to the sequence of the vaccine itself
269 age 4 months to receive whole-egg powder or placebo (rice powder) until 8 months of age, with all ot
270 assigned patients to receive tDCS plus oral placebo, sham tDCS plus escitalopram, or sham tDCS plus
272 tive voice-response system to eltrombopag or placebo, stratified by baseline platelet count (<10 x 10
274 none who received placebo; as compared with placebo, tofacitinib was associated with increased lipid
275 eight, oral or intravenous) versus identical placebo, together with standard antibiotic therapy.
277 ped normal glucose tolerance compared with 8 placebo-treated participants (16.0%) (P < .001; number n
281 hile a similar interaction was observed with placebo treatment, treatment with estradiol attenuated t
287 ses were 0, 43, and 130 mg of protein in the placebo, VP100, and VP250 groups, respectively (placebo
288 cebo, VP100, and VP250 groups, respectively (placebo vs VP100, P = .014; placebo vs VP250, P = .003).
290 t with testosterone for 1 year compared with placebo was not associated with improved memory or other
291 ned to BIIB074 versus nine (64%) assigned to placebo were classified as treatment failures (p=0.0974)
293 Changes in both seladelpar groups versus placebo were significant (p<0.0001 for both groups vs pl
294 t severe adverse events (>4% difference from placebo) were diarrhoea (eight [11%] of 70 in the masiti
295 carbose (50 mg three times a day) or matched placebo, which was added to standardised cardiovascular
296 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority
297 administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiori
298 The least-squares mean difference versus placebo with respect to the absolute change in the perce
299 ere significant (p<0.0001 for both groups vs placebo), with no significant difference between the two
300 the most common local adverse events versus placebo within the first 14 days were arm pain (57.4% [2
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