ライフサイエンスコーパス: planar cell polarity

1 lia are polarized coordinately and display a planar cell polarity.

2 the apical membrane during the initiation of planar cell polarity.

3 protein (BMP) signaling, cell migration, and planar cell polarity.

4 g pathway that regulates Hippo signaling and planar cell polarity.

5 suggest that Dchs1-Fat4 signaling influences planar cell polarity.

6 but not directly in MET channel function or planar cell polarity.

7 fluid flow and the developmental process of planar cell polarity.

8 ing network regulates both transcription and planar cell polarity.

9 and gene expression but not its influence on planar cell polarity.

10 that regulates growth, gene expression, and planar cell polarity.

11 on, synaptogenesis, and the establishment of planar cell polarity.

12 nopus oocyte contains components of both the planar cell polarity and apical-basal polarity pathways,

13 d on the embryo have been used in studies on planar cell polarity and as models for the cytoskeletal

14 These include sonic hedgehog, wingless, planar cell polarity and fibroblast growth factor, which

15 mutant hair cells also displayed defects in planar cell polarity and morphogenesis of the stereocili

16 TK7 pseudo-kinase plays an essential role in planar cell polarity and the non-canonical Wnt pathway i

17 g signaling pathway, resulting in defects of planar cell polarity and tissue maintenance.

18 larize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts

19 The mechanisms of planar cell polarity are being revealed by genetic analy

20 on, alteration of intracellular calcium, and planar cell polarity are examined.

21 oliferation but instead resulted in aberrant planar cell polarity as manifested by abnormalities in t

22 PRICKLE2 distribution reveals the planar cell polarity axis in the underlying epithelium i

23 Other epithelia need Rho-kinase for planar cell polarity but it is not known whether Rho-kin

24 cal cadherin Fat is a conserved regulator of planar cell polarity, but the mechanisms by which Fat co

25 a signaling pathway that controls growth and planar cell polarity by regulating the membrane localiza

26 e Ror receptor tyrosine kinase CAM-1 and the planar cell polarity component Van Gogh/VANG-1.

27 nd that 5-HT and mdDA axons express the core planar cell polarity components Frizzled3, Celsr3, and V

28 In the nephron, planar cell polarity controls elongation along the proxi

29 , interactions and functions of the maternal planar cell polarity core protein Vangl2 and the apical-

30 Initially, planar cell polarity determines the orientation of LEC m

31 ed by regulation of cell differentiation and planar cell polarity during development.

32 the CNV showed discrete contributions of the planar cell polarity effector SCRIB and the splicing fac

33 ophila and for its conserved function during planar cell polarity establishment.

34 eractions between three proteins involved in planar cell polarity: Flamingo, Frizzled and Van Gogh.

35 Fat not only regulates growth but also planar cell polarity, for which it interacts with the Da

36 Vangl2, a core component in planar cell polarity, forms Wnt-induced receptor complex

37 Frizzled/planar cell polarity (Fz/PCP) signaling controls the ori

38 be in detail two of these: a mutation in the planar cell polarity gene scribbled homolog (Drosophila)

39 Mutations in the core planar cell polarity gene Van Gogh-like 2 (Vangl2) resul

40 When combined with a mutant allele of the planar cell polarity gene Vangl2 (Vangl2(Lp)), Fz1 and/o

41 roles for planar polarity and for the novel planar cell polarity gene, Ptk7, as essential regulators

42 These findings show that planar cell polarity genes are required for responses to

43 the cue, and reoriented mitosis required the planar cell polarity genes dachsous, fat, and atrophin.

44 ctorin-based matrix, epithelial cilia or the planar cell polarity genes Vangl2 and Ptk7 In wild-type

45 for pineapple eye, likewise dependent on the planar cell polarity genes.

46 at regulate folate one-carbon metabolism and planar cell polarity have been strongly implicated.

47 Fat-Dachsous signaling systems locally align planar cell polarities in Drosophila epithelia.

48 The frizzled/starry night pathway regulates planar cell polarity in a wide variety of tissues in man

49 he conserved frizzled (fz) pathway regulates planar cell polarity in both vertebrate and invertebrate

50 gnaling/signal transduction pathway controls planar cell polarity in both vertebrates and invertebrat

51 echanism also contribute to the formation of planar cell polarity in mechanosensory epithelia.

52 cle orientation depends on genes that define planar cell polarity in the epidermis.

53 ry cilia are required for the maintenance of planar cell polarity in the mammalian kidney and that ac

54 ommatidial rotation, functional readouts of planar cell polarity in the wing and eye respectively, a

55 Rap1 is also necessary for planar cell polarity in these tissues.

56 play a conserved role in cilia formation and planar cell polarity in zebrafish.

57 g and genetic analysis of proteins linked to planar cell polarity (Inturned, Fuzzy and Wdpcp), we ide

58 These results suggest that ependymal planar cell polarity is a multistep process initially or

59 gh their hair bundles develop normally their planar cell polarity is compromised.

60 Once the planar cell polarity is established, microtubules are no

61 Planar cell polarity is normal in the vestibular epithel

62 as grossly normal in the cochlea, indicating planar cell polarity is not markedly affected.

63 Moreover, the planar-cell-polarity member, Prickle-1, is recruited spe

64 on CE is robust to relatively high levels of planar cell polarity misalignment and to the presence of

65 ements of cell polarity suggest that classic planar cell polarity molecules are not directly influenc

66 cts at least partially independently of core planar cell polarity molecules at the plasma membrane, a

67 egulation of Kif12 may underlie the abnormal planar cell polarity observed in cystic kidney diseases.

68 ling during kidney morphogenesis affects the planar cell polarity of the epithelium and leads to tubu

69 xpansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/m

70 The planar cell polarity pathway and hydrodynamic forces hav

71 g in a novel pathway, independently from the planar cell polarity pathway and in parallel to lin-17/f

72 eover, we demonstrate that components of the planar cell polarity pathway colocalize to recycling end

73 Here we show that the Dchs1-Fat4 planar cell polarity pathway controls cell orientation i

74 ry sensory organ, the Usher complex, and the planar cell polarity pathway in the formation and polari

75 Although the traditional planar cell polarity pathway is not involved, we obtaine

76 Medio-lateral cell intercalation and the planar cell polarity pathway play a role during this ear

77 ng satellite stem cell expansion through the planar cell polarity pathway, as well as myofiber hypert

78 Vangl2, a core component of the Planar Cell Polarity pathway, is necessary for the cauda

79 molecular control via the non-canonical Wnt/planar cell polarity pathway, Shh/BMP signalling, and th

80 lamingo/CELSR, an essential component of the planar cell polarity pathway.

81 enter through a mechanism reminiscent of the planar cell polarity pathway.

82 progenitor movement that is dependent on the planar cell polarity pathway.

83 tion between genes of the non-canonical Wnt (planar cell polarity) pathway and NTDs provides candidat

84 nraveling novel and unexpected functions for planar cell polarity pathways in HSC fate.

85 et genes not by signalingviathe WNT/Ca(2+)or planar cell polarity pathways, but rather by inhibiting

86 nts of the highly conserved apical-basal and planar cell polarity pathways, suggesting a possible reg

87 vertebrate neural tube formation, connecting planar cell polarity patterning to contraction of specif

88 hs1 signalling has been proposed to regulate planar cell polarity (PCP) and activity of the Hippo eff

89 f cells form as a result of coupling between planar cell polarity (PCP) and anisotropic tissue-scale

90 The Frizzled/planar cell polarity (PCP) and anterior-posterior (AP) p

91 r and slope of morphogen gradients influence planar cell polarity (PCP) and growth.

92 The Fat pathway controls both planar cell polarity (PCP) and organ growth.

93 ila protocadherin Fat (Ft) regulates growth, planar cell polarity (PCP) and proximodistal patterning.

94 The generation of planar cell polarity (PCP) and tissue shape during morph

95 The PCP effector gene Inturned regulates planar cell polarity (PCP) and wing hair formation in Dr

96 e demonstrate that several components of the planar cell polarity (PCP) arm of non-canonical Wnt sign

97 ssues appeared normal in mice lacking a core planar cell polarity (PCP) component, Vangl2.

98 The absence of planar cell polarity (PCP) core proteins Prickle1 and Pr

99 Planar cell polarity (PCP) describes the polarization of

100 Using this platform, we show that the planar cell polarity (PCP) effector Fuz was required for

101 Planar cell polarity (PCP) establishes polarity within a

102 he two mouse homologues of a Drosophila core planar cell polarity (PCP) gene Van Gogh (Vang), we reve

103 The pathway is a hierarchy with the Planar Cell Polarity (PCP) genes (aka the core genes) fu

104 Mutations in multiple planar cell polarity (PCP) genes can cause swirling patt

105 Here we show that mutations in the planar cell polarity (PCP) genes Celsr1 and Vangl2 lead

106 Here we report that the planar cell polarity (PCP) genes Celsr3 and Fzd3 are req

107 Recently, several planar cell polarity (PCP) genes have been implicated in

108 ertebrate homologues of core tissue polarity/planar cell polarity (PCP) genes in Drosophila.

109 The Wnt/Planar cell polarity (PCP) has been associated with cili

110 Establishment of planar cell polarity (PCP) in a tissue requires coordina

111 gnaling/signal transduction pathway controls planar cell polarity (PCP) in both vertebrates and inver

112 (Fzr/Cdh1) in epithelial cell patterning and planar cell polarity (PCP) in Drosophila.

113 Acquisition of planar cell polarity (PCP) in epithelia involves interce

114 Planar cell polarity (PCP) in epithelia, orthogonal to t

115 tracellular molecular machinery that directs planar cell polarity (PCP) in epithelial tissues, includ

116 nd Dachsous (Ds) have been found to underlie planar cell polarity (PCP) in many tissues.

117 Ft, Ds, and Fj are also required for normal planar cell polarity (PCP) in the wing, abdomen, and eye

118 led/starry night (fz/stan) pathway regulates planar cell polarity (PCP) in vertebrates and invertebra

119 Planar cell polarity (PCP) is a common feature of many e

120 Planar cell polarity (PCP) is a property of epithelial t

121 Planar cell polarity (PCP) is a ubiquitous property of a

122 Planar cell polarity (PCP) is an important conserved pro

123 In dividing cells of the mammalian skin, planar cell polarity (PCP) is maintained through the bul

124 A key step in generating planar cell polarity (PCP) is the formation of restricte

125 fish morphants are similar to those found in planar cell polarity (PCP) mutants, a pathway suggested

126 ensory organ to exhibit a particular form of planar cell polarity (PCP) necessary for mechanotransduc

127 function is the rotational and translational planar cell polarity (PCP) of E1 cells.

128 Components of the planar cell polarity (PCP) pathway are required for the

129 Here, we provide evidence implicating the planar cell polarity (PCP) pathway as the downstream com

130 ferative divisions, and the re-expression of planar cell polarity (PCP) pathway components.

131 The vertebrate planar cell polarity (PCP) pathway consists of conserved

132 I found that components of the Wnt/Planar Cell Polarity (PCP) pathway control MB axon branc

133 The noncanonical Wnt/planar cell polarity (PCP) pathway controls a variety of

134 The planar cell polarity (PCP) pathway controls multiple cel

135 ong et al. add to mounting evidence that the planar cell polarity (PCP) pathway coordinates posterior

136 n by regulating the evolutionarily conserved planar cell polarity (PCP) pathway during embryonic morp

137 including beta-catenin and non-canonical Wnt/planar cell polarity (PCP) pathway factors, such as Daam

138 Recent work implicates a non-canonical Wnt/planar cell polarity (PCP) pathway in the regulation of

139 The planar cell polarity (PCP) pathway is a conserved non-ca

140 The planar cell polarity (PCP) pathway is a conserved pathwa

141 The planar cell polarity (PCP) pathway is best known for its

142 Recent studies established that the planar cell polarity (PCP) pathway is critical for vario

143 The planar cell polarity (PCP) pathway is necessary for the

144 The planar cell polarity (PCP) pathway is required for fetal

145 The Wnt-planar cell polarity (PCP) pathway is the primary regula

146 The planar cell polarity (PCP) pathway organizes the cytoske

147 The evolutionarily conserved planar cell polarity (PCP) pathway regulates CE, and Wnt

148 The Wnt/planar cell polarity (PCP) pathway regulates directed ce

149 importance in development and physiology the planar cell polarity (PCP) pathway remains one of the mo

150 The vertebrate planar cell polarity (PCP) pathway shares molecular comp

151 facilitate a switch to the non-canonical Wnt planar cell polarity (PCP) pathway that is involved in c

152 gration is directed by the non-canonical Wnt planar cell polarity (PCP) pathway via Rho/ROCK.

153 Additionally, glypicans function in the planar cell polarity (PCP) pathway, and several PCP gene

154 at Celsr3 and Vangl2, core components of the planar cell polarity (PCP) pathway, are localized at dev

155 Several components of the Wnt/planar cell polarity (PCP) pathway, including the transm

156 The planar cell polarity (PCP) pathway, incorporating non-ca

157 of Vangl2, a transmembrane component of the planar cell polarity (PCP) pathway, rescued recessive Da

158 The Wnt planar cell polarity (PCP) pathway, through the recruitm

159 y-Legs (Pk) is an essential component of the planar cell polarity (PCP) pathway, together with Frizzl

160 d PAH pericytes for abnormalities in the Wnt/planar cell polarity (PCP) pathway, which has been shown

161 Some of these processes signal via the planar cell polarity (PCP) pathway, which is a beta-cate

162 ochord taper involves three main mechanisms: Planar Cell Polarity (PCP) pathway-independent sibling c

163 n and seems to require signaling through the planar cell polarity (PCP) pathway.

164 of the primary body axis and depends on the planar cell polarity (PCP) pathway.

165 lypican 4, an essential component of the Wnt/planar cell polarity (PCP) pathway.

166 regulator of both the canonical Wnt and the planar cell polarity (PCP) pathway.

167 eta-catenin pathway and the noncanonical Wnt/planar cell polarity (PCP) pathway.

168 PTK7 is an essential component of the Wnt/planar cell polarity (PCP) pathway.

169 proteins functioning in a non-canonical Wnt/Planar Cell Polarity (PCP) pathway.

170 interfere with gastrulation mediated by the planar cell polarity (PCP) pathway.

171 ommon planar axis specified by the conserved planar cell polarity (PCP) pathway.

172 Noncanonical Wnt/planar cell polarity (PCP) pathways contribute to proces

173 Planar cell polarity (PCP) pathways have been defined by

174 adherin Fat is a receptor for both Hippo and planar cell polarity (PCP) pathways.

175 thway, including Wnt5b and the transmembrane planar cell polarity (PCP) protein Vangl2.

176 Planar cell polarity (PCP) proteins are distributed norm

177 ermis whereupon cell division, transmembrane planar cell polarity (PCP) proteins are removed from the

178 Core planar cell polarity (PCP) proteins are well known to re

179 We report here that planar cell polarity (PCP) proteins control convergent e

180 The core planar cell polarity (PCP) proteins coordinate the orien

181 Asymmetric localization of planar cell polarity (PCP) proteins is essential for tis

182 increased levels of transcripts encoding the planar cell polarity (PCP) proteins SCRIB and VANGL1 cor

183 nization and require the concerted action of planar cell polarity (PCP) proteins that regulate cell e

184 ir cell bundle alignment is mediated by core planar cell polarity (PCP) proteins, such as Vangl2, tha

185 symmetric subcellular localization of 'core' planar cell polarity (PCP) proteins, we find that altern

186 Planar cell polarity (PCP) refers to coordinated polariz

187 Planar cell polarity (PCP) refers to the collective alig

188 Planar cell polarity (PCP) refers to the coordinated ali

189 Planar cell polarity (PCP) regulates basal body (BB) doc

190 Planar cell polarity (PCP) regulates cell alignment requ

191 Planar cell polarity (PCP) regulates the orientation of

192 orientation are manifestations of epithelial planar cell polarity (PCP) required for proper perceptio

193 Planar cell polarity (PCP) requires the asymmetric sorti

194 Commissural axons engage planar cell polarity (PCP) signaling components to turn

195 Core planar cell polarity (PCP) signaling controls OCD and CE

196 Planar cell polarity (PCP) signaling controls the polari

197 Planar cell polarity (PCP) signaling controls tissue mor

198 Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell or

199 et of signaling pathways and the role of Wnt/Planar cell polarity (PCP) signaling in adult neurogenes

200 These experiments implicate planar cell polarity (PCP) signaling in motor axon growt

201 Moreover, we find that blocking planar cell polarity (PCP) signaling in somitic muscle c

202 work has implicated Frizzled6 (Fz6)-mediated planar cell polarity (PCP) signaling in the initial spec

203 A role for planar cell polarity (PCP) signaling in the orientation

204 Wnt-Frizzled/Planar cell polarity (PCP) signaling is a conserved mech

205 Planar cell polarity (PCP) signaling is a key regulator

206 Planar cell polarity (PCP) signaling is essential for me

207 Planar cell polarity (PCP) signaling is essential in det

208 This regulatory link between Shh and planar cell polarity (PCP) signaling may also occur in o

209 Much of the Hippo and planar cell polarity (PCP) signaling mediated by the Dro

210 Frizzled (Fz)/planar cell polarity (PCP) signaling orchestrates cytosk

211 Here we provide evidence that planar cell polarity (PCP) signaling orchestrates direct

212 During vertebrate gastrulation, Wnt/planar cell polarity (PCP) signaling orchestrates polari

213 Planar cell polarity (PCP) signaling orients development

214 The planar cell polarity (PCP) signaling pathway governs col

215 The planar cell polarity (PCP) signaling pathway is crucial

216 wingless (Wnt)-beta-catenin (betaC) and Wnt-planar cell polarity (PCP) signaling pathways to facilit

217 Non-canonical Wnt/planar cell polarity (PCP) signaling plays a primary rol

218 o worms, whether and how this is mediated by planar cell polarity (PCP) signaling remain elusive.

219 We show that planar cell polarity (PCP) signaling specifies direction

220 An evolutionarily conserved planar cell polarity (PCP) signaling system employs intr

221 The planar cell polarity (PCP) signaling system governs many

222 polarity is controlled by non-canonical Wnt/planar cell polarity (PCP) signaling, the hair cell-intr

223 g a candidate approach for genes involved in planar cell polarity (PCP) signaling, we identified Dros

224 cal beta-catenin signaling and Frizzled (Fz)-planar cell polarity (PCP) signaling.

225 sion (CE) defects, arising from impaired Wnt/planar cell polarity (PCP) signaling.

226 ther non-canonical pathways, WNT5A activates planar cell polarity (PCP) signaling.

227 ed cell autonomously in Wnt/beta-catenin and planar cell polarity (PCP) signaling.

228 The role of planar cell polarity (PCP) signalling in neural crest (N

229 Planar cell polarity (PCP) signalling is a well-conserve

230 Wnt planar cell polarity (PCP) signalling is critical in ver

231 to results from transgenic embryos in which Planar Cell Polarity (PCP) signalling is disrupted.

232 show that Scribble, a protein implicated in planar cell polarity (PCP) signalling, is necessary for

233 ateral polarization was under the control of planar cell polarity (PCP) signalling, was necessary for

234 Here, we show that in response to planar cell polarity (PCP) signals, Ral modulates asymme

235 Planar cell polarity (PCP) solves a similar morphogeneti

236 n the ASP was dependent on components of the planar cell polarity (PCP) system in the disc, and neith

237 nd physiology of tissues and organs requires planar cell polarity (PCP) systems that orient and coord

238 PTK7 regulates epithelial morphogenesis and planar cell polarity (PCP) through modulation of actomyo

239 n of this flow requires the establishment of planar cell polarity (PCP) whereby MCCs align hundreds o

240 ntation within the plane of a tissue, termed planar cell polarity (PCP), appear to be crucial for the

241 Many epithelia have a common planar cell polarity (PCP), as exemplified by the consis

242 lls within the plane of the tissue, known as planar cell polarity (PCP), is a recurring theme in biol

243 n of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segrega

244 d identified genes required for PR survival, planar cell polarity (PCP), patterning and differentiati

245 Planar cell polarity (PCP), the coordinated and consiste

246 ften coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the e

247 The Ciona notochord displays planar cell polarity (PCP), with anterior localization o

248 mmon pathway suggestive of activation of wnt-planar cell polarity (PCP)-c-Jun N-terminal kinase (JNK)

249 Rosette dynamics are regulated by both planar cell polarity (PCP)-dependent and -independent pa

250 reociliary bundles, indicative of defects in planar cell polarity (PCP).

251 nt Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP).

252 ized, with a pattern suggestive of defective planar cell polarity (PCP).

253 have only recently been linked to a role in planar cell polarity (PCP).

254 nal to the apical-basal axis, referred to as planar cell polarity (PCP).

255 r studying the genetic control of epithelial Planar Cell Polarity (PCP).

256 beta-catenin-mediated gene transcription and planar cell polarity (PCP).

257 originally in flies to coordinate epithelial planar cell polarity (PCP).

258 ia have been implicated in the generation of planar cell polarity (PCP).

259 The planar cell polarity (PCP; non-canonical Wnt) pathway is

260 This is generally referred to as planar cell polarity (PCP; or historically, tissue polar

261 Planar-cell-polarity (PCP) signalling is necessary for i

262 ts of canonical and noncanonical (Ca(2+) and planar cell polarity [PCP]) Wnt pathways, including IWP-

263 The Wnt-PCP (planar cell polarity, PCP) pathway regulates cell polari

264 restingly, dyl mutants also display a unique planar cell polarity phenotype that is distinct from tha

265 PTK7, a tyrosine kinase receptor involved in planar cell polarity, plays a role in epithelial Wnt sig

266 tunes dishevelled levels, thereby modulating planar cell polarity processes.

267 nder flow and exhibit high expression of the planar cell polarity protein VANGL2.

268 The latter - planar cell polarity - requires long-range regulation of

269 After NCC delamination, planar cell polarity signaling acts via RhoGTPases to co

270 this ciliopathy that (i) implicate ALMS1 in planar cell polarity signaling and (ii) suggest that the

271 The only known ligands for planar cell polarity signaling are Wnt proteins.

272 First, PAPC attenuates planar cell polarity signaling at the ectoderm-mesoderm

273 LIN-17 phosphorylation and is antagonized by planar cell polarity signaling components Van Gogh (VANG

274 ata suggest an important role for Ryk in Wnt/planar cell polarity signaling during vertebrate develop

275 Perturbation analyses demonstrate that planar cell polarity signaling enables cells to pivot in

276 Fat2/Lar signaling is similar to planar cell polarity signaling in terms of sub-cellular

277 Here we reveal a novel requirement for Wnt/planar cell polarity signaling in the anterior-posterior

278 Overall, our data suggest that Wnt/planar cell polarity signaling may be a global anterior-

279 Wnt-11/planar cell polarity signaling polarizes mesodermal cell

280 In this study we demonstrate that planar cell polarity signaling regulates morphogenesis i

281 e reporters, that WNT11 strongly induced JNK/planar cell polarity signaling while repressing the beta

282 Celsr1, a likely indicator of competence for planar cell polarity signaling.

283 ryos mutant for two proteins associated with planar cell polarity signaling: Vangl2 and Ptk7.

284 Wnt/beta-catenin signalling and disrupts Wnt/planar cell polarity signalling in vivo.

285 ase 1 gene (ROCK1) is a key component of the planar cell polarity signalling pathway, which plays an

286 nother non-canonical Wnt pathway involved in planar cell polarity, suggesting that these two pathways

287 ost entirely by Dachsous and Fat, one of two planar cell polarity systems.

288 of research there are still basic aspects of planar cell polarity that are not well understood.

289 Oriented cell division is a feature of planar cell polarity that describes the orientation of t

290 he non-canonical Wnt-dependent regulation of planar cell polarity through the Formin homology protein

291 is an evolutionarily conserved regulator of planar cell polarity, tissue size and cell adhesion.

292 We demonstrate spindle alignments and planar cell polarities, which form a novel functional un

293 dent on Rho kinase, JNK and, to some extent, planar cell polarity within the epidermis.

294 onent of both the canonical and noncanonical/planar cell polarity Wnt pathways, modulates cell polari

295 The data suggest that JNK/planar cell polarity WNT signaling operates in the face

296 The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial r

297 The non-canonical WNT/planar cell polarity (WNT/PCP) pathway plays important r

298 the Wnt/calcium (Wnt/Ca) pathway and the Wnt/planar cell polarity (Wnt/PCP) pathway, in certain cellu

299 Wnt planar cell polarity (Wnt/PCP) signaling polarizes the m

300 orphogenesis (in particular the emergence of planar cell polarity), wound healing, and disease-progre