ライフサイエンスコーパス: plasma

1 0Met mutation detectable in tumour tissue or plasma.

2 cal thiols such as glutathione) and in human plasma.

3 w, CSF, circulating CD4+ T cell subsets, and plasma.

4 apture of MC-LR from aqueous media and blood plasma.

5 nano-scale coherent x-ray sources in a laser plasma.

6 aphy to purify HBeAg from individual patient plasmas.

7 ients with IBD were also analyzed along with plasma 25-hydroxy vitamin D3 (25D) detection.

8 vely correlates to levels of soluble CD14 in plasma, a marker of chronic immune activation.

9 bubble activity significantly increases the plasma abundance of tumor-derived microRNA rapidly after

10 within the range of 0.1 to 10 ng.mL(-1) for plasma and 0.25 to 10 ng.mL(-1) for urine.

11 Plasma and CSF collected pre-ART were assayed for cytoki

12 pinal fluid (CSF) viral rebound or sustained plasma and CSF viremia during treatment.

13 Metabolomics analyses of human plasma and HaCaT cells were used to compare the above th

14 PET data were analyzed using plasma and reference tissue-based methods to estimate th

15 Carotenoid levels in plasma and skin were quantitated, with total lycopene hi

16 Plasma and tissue HIV RNA correlated at baseline and whe

17 In vivo plasma and urine stability analysis showed intact (18)F-

18 relevant conditions such as in platelet-rich plasma and whole blood.

19 from the proteins that are present in human plasma, and some of the peptides are capable of distingu

20 Activity was determined in whole blood, plasma, and urine.

21 To explore this, serum, plasma, and whole blood from 61 adults in Oslo, Norway w

22 Multiple myeloma (MM) is a plasma B-cell hematologic cancer that causes significant

23 Perfusate was plasma-based with a hemoglobin concentration of 4 to 6 g

24 ived from a food-frequency questionnaire and plasma biomarker concentrations that were collected simu

25 Plasma biomarkers reflecting activation of procoagulatio

26 The incremental area under the plasma C-peptide concentration curve during the hypergly

27 h and 14 days, respectively (P < 0.01); the plasma C-peptide response remained unchanged in subjects

28 ed to identify how MGUS and multiple myeloma plasma cell clones responded to anti-multiple myeloma th

29 Finally, plasma cell differentiation of sorted LPS-stimulated MZ

30 In multiple myeloma (MM), a plasma cell malignancy, most tumors display hallmarks of

31 To characterize plasma cell-free eccDNAs, we performed sequencing analys

32 is known about the biology of amyloidogenic plasma cells (PCs).

33 A) are constitutively secreted by intestinal plasma cells to coat and contain the commensal microbiot

34 ovascular pathology.Higher concentrations of plasma choline were associated with an unfavorable cardi

35 n-like peptide 1 (GLP-1) immunoreactivity of plasma collected immediately before and at 15, 30, 60, 9

36 , giving the conversion formula: (creatinine plasma concentration in mumol/L) = (creatinine concentra

37 The unlabeled drug dose and plasma concentration leading to a 50% reduction of (11)C

38 d cediranib area under the curve and maximum plasma concentration on the daily, but not intermittent,

39 Plasma concentrations of 200 proteins changed significan

40 Plasma concentrations of amino acids (AAs), in particula

41 Plasma concentrations of free choline, betaine, and phos

42 Plasma concentrations of glyoxal are elevated in in diab

43 Elevated serum and plasma concentrations of MMP-8 are associated with the r

44 Plasma concentrations of triglycerides were measured imm

45 We confirmed that human plasma contains immunoglobulins that can neutralize ILY,

46 er assessed whether concentrations of NfL in plasma correlated with those in CSF.

47 treatment on body condition, immune metrics, plasma corticosterone concentrations, total antioxidant

48 tropin (250 mug) administration and a random plasma cortisol of < 10 mug/dL may be used by clinicians

49 l decline, muscle strength and survival with plasma creatinine were assessed.

50 In this validation cohort, plasma derived exosomal miRNA was isolated from 50 early

51 oned equivalently, matching or outperforming plasma-derived CFH, whereas R53H-CFH, linked to atypical

52 method for total transcriptome profiling of plasma-derived EVs by next generation sequencing (NGS) f

53 Total RNA extracted from plasma-derived EXOs of 12 T1DM and 12 control subjects w

54 as biomarkers for T1DM, miRNA expression in plasma-derived exosomes was measured.

55 g RONS speciation and delivery depth, or how plasma-derived RONS intervene in biological processes.

56 ng nanoelectrospray ionization (nanoESI) and plasma discharge ionization.

57 consistent product release, revaccination of plasma donors was investigated as a means to boost titer

58 apabilities of the dual-pulse to control the plasma-driven fluid dynamics by adjusting the axial offs

59 of autophagy led to 50-fold increases in the plasma drug concentration of the viral integrase inhibit

60 Genotypes that predict higher plasma efavirenz exposure were associated with increased

61 the relatively hydrophilic surface after O2 plasma etching provided better resistance to fouling tha

62 standard lithography and inductively coupled plasma etching, the Si substrate was prepared with very

63 To retrospectively analyze the effect of plasma exchange (PLEX; yes = PLEX(+) , no = PLEX(-) ) an

64 ith acquired TTP respond to a combination of plasma exchange and rituximab, but some die or acquire i

65 his follow-up study demonstrated circulating plasma exosomal miR-125a-3p is readily accessible as dia

66 Inhibiting the fall of plasma FFAs in these mice prevented the suppression of E

67 complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a

68 uce fibrinogen production, thereby elevating plasma fibrinogen levels.

69 an experimental demonstration of controlling plasma flow direction with a magnetic nozzle consisting

70 iation from "noise", arising from stochastic plasma fluctuations that competes with externally inject

71 The efficacy of cold plasma for inactivation of food-borne pathogens in foods

72 re measured by LC-MS/MS in maternal and cord plasma from 259 Caucasian women at delivery (BMI 18-55 k

73 f fractionated eluates by SRM (SAFE-SRM), to plasma from cancer patients and discovered two peptides

74 e methodology was further blindly applied to plasma from remote ischemic pre-conditioning (RIPC) rats

75 he metabolome were studied in the livers and plasma from these mice.

76 the inherent physical separation between the plasma generation region and downstream point of applica

77 regulated by feeding time and could underpin plasma glucose changes.

78 Empagliflozin reduced the plasma glucose concentration threshold for glucose spill

79 g/dL, which is well below the normal fasting plasma glucose concentration.

80 to release insulin in response to changes in plasma glucose concentration.

81 Mean +/- SEM pre- and postfilter venous plasma glucose concentrations in the aggregate group wer

82 ctor to discern the concentration of average plasma glucose over a long-drawn-out period.

83 the mixed meal induced a greater increase in plasma glucose, insulin, and GIP concentrations after su

84 onal ultrasonography), and blood glucose and plasma gut-hormone concentrations [insulin, glucagon, gh

85 iance estimators and included adjustment for plasma HIV VL.

86 ticipants with less than 50 copies per mL of plasma HIV-1 RNA at week 48 (by the US Food and Drug Adm

87 th CD4+ counts >350 cells/muL and detectable plasma HIV-1 RNA by single-copy assay.

88 -1 transcription was quantified by measuring plasma HIV-1 RNA during MGN1703 administration.

89 oint was the proportion of participants with plasma HIV-1 RNA of less than 50 copies per mL at week 4

90 during very early Fiebig stage I (detectable plasma HIV-1 RNA, antibody negative) followed by 4-drug

91 olyte content, are common and ascertained by plasma hypo- or hypernatremia, respectively.

92 tive SPT or elevated allergen-specific serum/plasma IgE levels.

93 score [ISS] = 20.2) exhibited elevations in plasma IL33 levels upon admission and over time that cor

94 ge required to realize the full potential of plasma in biology and medicine.

95 ion (called pedestal) of magnetized toroidal plasma in the KSTAR tokamak device.

96 luded analysis of in vivo FLT3 inhibition by plasma inhibitory activity assay and indicated improved

97 d two-tissue compartment model with arterial plasma input function with total volume of distribution

98 ng a 3 GeV electron beam through a two-stage plasma insertion device.

99 electrospray ionization, and low temperature plasma ionization.

100 n sequestration in macrophages and decreased plasma iron; this is proposed to limit the replication o

101 o tetherin but that virion dissemination via plasma is inhibited by tetherin and is required for full

102 can be introduced without extinguishing the plasma is limited to about 4mg.

103 Proteomic characterization of blood plasma is of central importance to clinical proteomics a

104 h IFNbeta, but not IFNalpha2, selected donor plasma isolates that exhibited a transmitted virus-like

105 d temporally-varying interaction between the plasma, its environment and external controls presents a

106 ssible without interfacial stratification of plasma jet to thin (of several microm) current filaments

107 easure the genotoxic and cytotoxic effect of plasma jet treatments (both indirect and direct) in divi

108 ble swelling episodes caused by uncontrolled plasma kallikrein generation and excessive bradykinin re

109 The plasma kynurenine/tryptophan (KT) ratio, a marker of ada

110 HIIT acutely increases plasma lactate levels.

111 ed yielding marked hypotension and a rise in plasma lactate.

112 ncreased hepatic LDLR expression and reduced plasma LDL concentrations in mice.

113 Plasma leakage and keratinocyte chemoattractant producti

114 and tight and adherens junction markers with plasma leakage.

115 Lactalbumin and lactoferrin decreased plasma leptin and insulin, and lactalbumin increased pep

116 E2 plasma levels (p = .092) and time period of measurement

117 used to detect interactions between hormonal plasma levels and ocular parameters.

118 Finally, we confirmed low 25D plasma levels in patients with IBD with active inflammat

119 Plasma levels of 17 cytokines were screened in the same

120 the association of genetic variants with the plasma levels of each of the 156 Framingham Cardiovascul

121 Plasma levels of fitusiran increased in a dose-dependent

122 , Tnfa, and Crp expression in WBCs, elevated plasma levels of IL-1beta, IL-6, and IL-8, increased IL-

123 To compare the circulating plasma levels of peptide YY and ghrelin in control subje

124 Plasma levels of PPi and the degree of ectopic mineraliz

125 cells in RIC mice and elevated blood and BM plasma levels of T helper1 cytokines.

126 Plasma levels of the inflammatory cytokine tumor necrosi

127 Basal plasma levels of von Willebrand factor and recruitment o

128 Despite enhanced weight gain and plasma lipid levels compared with Apoe(-/-) controls, Ep

129 ytosis of E. coli RA101295 treatment reduced plasma LPS content in E. coli-challenged baboons, implyi

130 collagen fractional synthesis rate (FSR) and plasma lumican FSR were measured based on (2) H labeling

131 There was no effect of MCH on fetal plasma/lung tissue cortisol concentrations, nor genes re

132 on of a highly sensitive inductively coupled plasma mass spectrometer coupled to a scanning flow cell

133 ique with multicollector inductively coupled plasma mass spectrometers.

134 -ray spectroscopy (EDX), inductively coupled plasma mass spectrometry (ICP-MS), amino acid analysis,

135 eases were quantified by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), single-particle-ICP-M

136 andard was determined by inductively coupled plasma mass spectrometry (ICPMS).

137 D47-QD was assessed with inductively coupled plasma mass spectrometry.

138 The nanosensor successfully worked in plasma matrixes.

139 Collective effects of the pair plasma may be also triggered, offering a window on inves

140 ion models were used to examine relations of plasma measures with cardiometabolic risk factors, histo

141 protein whose reversible localization to ER-plasma membrane (PM) contacts is governed by phosphoryla

142 stream signalling components, which exist in plasma membrane (PM)-localised protein complexes.

143 specialised extension of the oligodendrocyte plasma membrane and clemastine fumarate can stimulate di

144 reveals that Rab8a is first recruited to the plasma membrane and dorsal ruffles, but it is retained d

145 data reveal 2D dynamics of the mitochondria, plasma membrane and filopodia, and the 2D and 3D dynamic

146 the absence of RhoA, RhoB relocalized to the plasma membrane and functionally replaced RhoA with resp

147 CR membrane localization and dynamics at the plasma membrane and in endosomal compartments, (c) TCR s

148 aturation but co-localizes with PD-L1 at the plasma membrane and in recycling endosomes, where it pre

149 ch promotes the trafficking of Nav1.5 to the plasma membrane and stimulation of INa.

150 oscillations: Hechtian adhesion between the plasma membrane and the cell wall of the growing tip act

151 xpected synergies appear, including with the plasma membrane anion channels and H(+)-ATPase and with

152 e found that the K-Ras anchor binds selected plasma membrane anionic lipids with defined head groups

153 their correct assembly and expression at the plasma membrane as a single functional complex, (b) TCR

154 e show that this protein is localized at the plasma membrane as well as in endosomes and soluble in t

155 omer SGs that undergoes no residence time on plasma membrane before fusion and, to a lesser extent, a

156 or cells requires evagination of its ciliary plasma membrane by an unknown molecular mechanism.

157 pling may extend to the outer leaflet of the plasma membrane by examining the flow of GPI-anchored pr

158 the regulative N terminus of the Arabidopsis plasma membrane Ca(2+)-ATPase isoform 8 (ACA8) and that

159 -gated L-type Ca(2+) channels (LTCCs) in the plasma membrane can initiate a signaling pathway that ul

160 Sub-cellular investigations reveal that the plasma membrane cell fate regulator, SCRAMBLED (SCM), is

161 LRX proteins might play a role in cell wall-plasma membrane communication, influencing cell wall for

162 pin, among other phospholipids in the apical plasma membrane compared to the basolateral plasma membr

163 hown that CME proteins actively modulate the plasma membrane curvature.

164 PS asymmetry on the plasma membrane depends on the activities of P4-ATPases,

165 2+) homeostasis in excitable cells following plasma membrane depolarization.

166 To examine whether the structure of the axon plasma membrane determines its overall stiffness, we int

167 ne and its fluorescent analog JHC1-64 on the plasma membrane distribution of wild-type DAT and two no

168 triggers insertion of GLUT4 into the axonal plasma membrane driven by activation of the metabolic se

169 to decipher specific influences on molecular plasma membrane dynamics.

170 ane-derived exosomes, but not in basolateral plasma membrane exosomes from mouse cortical collecting

171 plasma membrane compared to the basolateral plasma membrane exosomes.

172 ensing is not dependent on its function as a plasma membrane folate transporter.

173 g and translocation of RodZ to the bacterial plasma membrane in an obligatorily cotranslational mecha

174 activity triggers lysosomal fusion with the plasma membrane in dendrites.

175 ot palmitoylated display drastically reduced plasma membrane localization, which effectively prevents

176 y discharge during invasion and to host cell plasma membrane lysis during egress.

177 rotein located and functioning at the apical plasma membrane of epithelial cells, is required for epi

178 In the plasma membrane of eukaryotic cells, proteins and lipids

179 Primary cilia are hairlike extensions of the plasma membrane of most mammalian cells that serve speci

180 Eukaryotic plasma membrane organization theory has long been contro

181 d phospholipase Cgamma, enzymes that deplete plasma membrane phosphatidylinositol 4,5-bisphosphate (P

182 ation study indicated that it is an integral plasma membrane protein.

183 While the plasma membrane proteome remained largely invariable, we

184 areas promote structural changes within the plasma membrane that segregate membrane receptors and af

185 a necrotic DFNA5-N fragment that targets the plasma membrane to induce secondary necrosis/pyroptosis.

186 TLR4, dimerize and move laterally across the plasma membrane to phosphatidylinositol (4,5)-bisphospha

187 otein which is usually found anchored to the plasma membrane via a glycophosphatidylinositol (GPI) an

188 PIN1 phosphorylation at the basal and apical plasma membrane was differentially sensitive to BFA trea

189 ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid compl

190 TF is much less efficiently localized to the plasma membrane, and it is not incorporated into the vir

191 have been developed to overcome the cellular plasma membrane, but they all result in reduced cell via

192 oteins expressed at the inner leaflet of the plasma membrane, including alpha-actinin-1, moesin, 14-3

193 ression of KCNQ1 trapped beta-catenin at the plasma membrane, induced a patent lumen in CRC spheroids

194 ia virus protein F11, which localizes to the plasma membrane, is required for ROCK-mediated cell cont

195 Ltc1 and Ltc3/4 function at the vacuole and plasma membrane, respectively, to create membrane domain

196 e triggered the fusion of lysosomes with the plasma membrane, resulting in the release of Cathepsin B

197 were normally processed and targeted to the plasma membrane, whereas their PC secretion activity was

198 DNER is present on the plasma membrane, while NFIA is confined to the nucleus,

199 Among them, the plasma membrane-associated Arabidopsis proteins OCTOPUS

200 Self-assembly of plasma membrane-associated Ras GTPases has major implica

201 The plasma membrane-associated tyrosine phosphatase PTPRO is

202 ein 90, were identified in samples of apical plasma membrane-derived exosomes, but not in basolateral

203 this phenomenon, here we confirmed that the plasma membrane-localized transporter (renamed CDR6/ROA1

204 rrival of the early and late proteins at the plasma membrane.

205 lation-mediated trafficking of Nav1.5 to the plasma membrane.

206 te (PI(4,5)P2), the main lipid marker of the plasma membrane.

207 n (MLKL), which results in disruption of the plasma membrane.

208 f G protein-coupled receptors (GPCRs) at the plasma membrane.

209 s from the outer to the inner leaflet of the plasma membrane.

210 (3,4,5)-triphosphate (PIP3) within the spine plasma membrane.

211 erstanding of signal transduction across the plasma membrane.

212 om the nucleus and assembled en route to the plasma membrane.

213 nd that the OsALMT4 protein localizes to the plasma membrane.

214 nalized GPR15 receptors were recycled to the plasma membrane.

215 also promoted translocation of NDPK-C to the plasma membrane.

216 rnal stress of a rapidly growing wall to the plasma membrane.

217 rafficking of KATP and Kv2.1 channels to the plasma membrane.

218 ease of the proteins from the vesicle to the plasma membrane.

219 the FAF1-VCP complex and reduces FAF1 at the plasma membrane.

220 ated vesicles prior to re-insertion into the plasma membrane.

221 Sphingolipids are a major component of plant plasma membranes and endomembranes, and mediate a divers

222 olve minute PKA activity microdomains on the plasma membranes of living cells and to uncover the role

223 e are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through th

224 eir ability to shuttle between endosomes and plasma membranes, as well as on their lateral accumulati

225 mains of these CARMIL isoforms interact with plasma membranes, vimentin intermediate filaments, SH3-c

226 tact and self-fusion of the apical and basal plasma membranes.

227 A combination of seven plasma metabolite biomarkers readily discriminates supra

228 Plasma metabolites and insulin were measured at baseline

229 pared with placebo, l-methylfolate increased plasma methylfolate levels (d=1.00, P=0.0009) and improv

230 Among 38 plasma miRNAs that were elevated following ischemia, eig

231 Using a two-dimensional numerical air plasma model, it is shown that the phase shift impacts t

232 Dietary and plasma n-6:n-3 ratio and n-3 predicted performance on wo

233 The plasma NFL analysis was performed in September 2016.

234 ent, and 180 patients with AD with dementia, plasma NFL correlated with CSF NFL (Spearman rho = 0.59,

235 Plasma NFL was increased in patients with MCI (mean, 42.

236 ely, when strain PC574 was cultured in human plasma, no similar increase in hemolytic activity was ob

237 dies indicated that these cells were neither plasma nor memory cells.

238 A) gene whose abundance was increased in the plasma of ovarian cancer patients.

239 samples was performed by inductively coupled plasma optical emission spectrometry and the digestion e

240 queous phase by means of inductively coupled plasma optical emission spectroscopy (ICP-OES).

241 of cooked rice using an inductively coupled plasma-optical emission spectroscopy.

242 We investigated whether plasma or cerebrospinal fluid (CSF) levels of cytokines

243 As compared to direct assays of plasma or leukocytes, the EV detection rate was signific

244 Although unique sequences in plasma or liver were observed, in the majority of cases

245 Exposure of cultured neurons to fetal plasma or to secretions from the placenta or from model

246 analysis reveal a strong association between plasma organophosphate residues and HbA1c but no associa

247 In human plasma, osmotic shock increased cBIN1 detection by enzym

248 lls were reliably characterized in recipient plasma over follow-up periods of up to 5 years.

249 Plasma oxidative stress (advanced oxidative protein prod

250 We further show that PF-06446846 reduces plasma PCSK9 and total cholesterol levels in rats follow

251 Plasma PCSK9 levels are associated with an increased ris

252 Higher concentrations of plasma phosphatidylcholine were associated with characte

253 ), which contributed to the reduction in the plasma pool sizes of these lipoprotein particles.

254 Plasma potassium concentration strongly and negatively c

255 We conclude that plasma profiling after STEMI may help identify patients

256 with cell-type-specific gene expression and plasma protein levels sheds light on potential disease m

257 s thrombin-catalyzed conversion of a soluble plasma protein, fibrinogen, into a polymeric fibrin clot

258 profiling of a larger portion of circulating plasma proteins (the plasma proteome) will provide oppor

259 Lastly, we used PECAN to build a plasma proteome library from DIA data and to query known

260 portion of circulating plasma proteins (the plasma proteome) will provide opportunities for unbiased

261 therefore receiving increasing attention in plasma proteomics.

262 Higher fresh frozen plasma ratios (> 1:2) were not associated with increased

263 The glomerular filtration rate and plasma renin, noradrenaline, lipopolysaccharide binding

264 We measured biomarkers from plasma samples collected in 211 patients using enzyme-li

265 microRNAs and their diagnostic potential in plasma samples of patients suffering from adrenocortical

266 ils from healthy controls exposed to patient plasma samples or exogeneous IFN-alpha.

267 ased protein profiling was applied to pooled plasma samples to enrich serine hydrolases using a fluor

268 n, quantitation with minimally processed rat plasma samples was demonstrated with three different sta

269 Skeletal muscle, liver, and plasma samples were analyzed by gas chromatography time-

270 Plasma samples were digested with trypsin and analyzed w

271 (exRNA) was isolated and sequenced from 183 plasma samples, 204 urine samples and 46 saliva samples

272 In all plasma samples, 98.8%-100% of CMV DNA was free DNA; this

273 ry (TBI) protein biomarker, in diluted blood plasma samples, achieving a LOD of 0.86 ng/mL.

274 and beta-blockers) spiked in human urine and plasma samples.

275 n of clinically significant proteoforms from plasma samples.

276 bolite GS-331007 were evaluated by intensive plasma sampling at day 7 in the first 10 patients enroll

277 LOAG_15846) of these proteins in individual plasma/serum samples.

278 dance proteins (e.g., </= 100 pg/mL in blood plasma/serum) using targeted proteomics approaches still

279 Metabolomic analysis of the liver and plasma shows a positive correlation between obesity and

280 Plasma soluble P-selectin (sP-selectin) is elevated thre

281 say, we measured HIV-1 RNA levels in CSF and plasma specimens from 220 HIV-positive adults who were t

282 le with different number of coils, forming a plasma structure similar to that observed in the experim

283 Interestingly, the direct plasma synthesis of acetic acid from CH4 and CO2 is an i

284 is regard: are there key advantages to using plasma technology over other novel approaches, and if so

285 served that patients with early increases in plasma TGF-beta1 concentrations had better outcomes 90 d

286 However, the exact nature of the initial plasma-tissue interactions remains unknown, including RO

287 This pathway is triggered upon exposure of plasma to certain anionic polymers and artificial surfac

288 Fresh frozen plasma-to-packed RBCs and platelets-to-packed RBCs ratio

289 Here we show that human cord plasma treatment revitalizes the hippocampus and improve

290 We found that plasma uridine levels are regulated by fasting and refee

291 The fatty acids were quantified in rumen and plasma using targeted MS to validate and evaluate the si

292 lipid metabolites in both the intestine and plasma via altered gut microbiota composition.

293 nital shedding among women with undetectable plasma viral load (VL).

294 ubjects with obese HFpEF displayed increased plasma volume (3907 mL [3563-4333 mL] versus 2772 mL [25

295 Herein, deidentified plasma was collected from sepsis patients (n = 22 subjec

296 Plasma was collected pre- and postoperatively as well as

297 Plasma was obtained from 128 patients with exudative AMD

298 Through blinded profiling of postoperative plasma, we observe evidence of adjuvant chemotherapy res

299 density, and coagulation rate of human blood plasma were measured along with the standard coagulation

300 ical analysis of the within-host dynamics of plasma ZIKV burden in a nonhuman primate model, allowing