ライフサイエンスコーパス: plasma aldosterone

1 ce often occur in concert with elevations in plasma aldosterone.

2 (4) These mice show higher levels of the plasma aldosterone.

3 phenotype, except for a 2.5-fold increase in plasma aldosterone.

4 decreased renal Na(+) avidity and increased plasma aldosterone.

5 ore than 50% without changing PCa++, PK+, or plasma aldosterone.

6 re (94 +/- 2 vs. 89 +/- 2 mm Hg, P = 0.002), plasma aldosterone (149 +/- 18 vs. 109 +/- 10 pmol/L, P

7 - 9 mg/d) and thrombotic microangiopathy and plasma aldosterone (18 +/- 18 pg/ml) remained low but da

8 HiPro versus CON rats had higher plasma aldosterone (60.9 +/- 5.9 versus 42.2 +/- 4.4 pg/

9 c, inappropriate (dietary Na+) elevations in plasma aldosterone (ALDO) and a catabolic state that inc

10 NH4Cl treatment significantly decreased plasma aldosterone and antidiuretic hormone concentratio

11 n, BKbeta1(-/-) strain A mice have increased plasma aldosterone and increased blood pressure.

12 of sodium in their feces and exhibited high plasma aldosterone and increased urinary sodium retentio

13 Despite life-long increase in plasma aldosterone and renin levels, no adverse cardiova

14 Low dietary Na+ intake raised rat plasma aldosterone and stimulated distal pericryptal she

15 Reduction in dietary Na+ intake raised plasma aldosterone and the capacity of the distal colon

16 The reduction of plasma renin activity, plasma aldosterone, and arginine vasopressin occurred ea

17 increase of plasma potassium (p < 0.02), but plasma aldosterone, angiotensin II (ANGII), and renin ac

18 ided clinical validation for the lowering of plasma aldosterone as a viable approach to modulate bloo

19 ets, conditional KO mice displayed decreased plasma aldosterone but normal Na+/K+ balance.

20 Plasma aldosterone but not plasma renin activity was sig

21 Eplerenone and amiloride each increased plasma aldosterone by 3-fold and renin concentration sli

22 In contrast, inducing high levels of plasma aldosterone by a variety of methods completely co

23 adrenal glands and a > 10-fold elevation in plasma aldosterone compared to SHAM.

24 ations nearly 20-fold, which correlated with plasma aldosterone concentration and urinary Na/K ratio.

25 nd no difference in plasma renin activity or plasma aldosterone concentration between salt-fed wild-t

26 tensive patient, a serum potassium level and plasma aldosterone concentration to plasma renin activit

27 f hypertension, higher preoperative ratio of plasma aldosterone concentration to plasma renin activit

28 Plasma aldosterone concentration was also measured.

29 dditional measurement of serum potassium and plasma aldosterone concentration-plasma renin activity r

30 KNG1]: P=0.001 for plasma renin, P=0.024 for plasma aldosterone concentration; and rs4253311 with P<0

31 Renal renin activity, tissue Ang II and plasma aldosterone concentrations did not differ between

32 First, under conditions of increased plasma aldosterone concentrations, the heart will extrac

33 ng, tissue renin activity, tissue Ang II and plasma aldosterone concentrations.

34 eart failure produces sustained reduction in plasma aldosterone, consistent with the observed signifi

35 Plasma aldosterone fell from 68 +/- 59 ng/dL at baseline

36 ke (120 +/- 124 versus 580 +/- 442 pg/ml for plasma aldosterone, group 1 versus group 2, P = 0.03, an

37 High plasma aldosterone has deleterious cardiovascular effect

38 In contrast, loss of BKbeta1 did not affect plasma aldosterone in strain C mice.

39 Plasma aldosterone increased with Fs (41+/-10 to 100+/-1

40 Plasma aldosterone is increased in NHE3-deficient mice,

41 Increases in systolic blood pressure, plasma aldosterone level, and urinary and heart prostano

42 Plasma aldosterone levels (P(aldo)) were comparable duri

43 Eleven of the 34 subjects had plasma aldosterone levels above the upper limit of norma

44 We simultaneously measured plasma aldosterone levels and the degree of inhibition o

45 Furthermore, elevated plasma aldosterone levels are associated with increased

46 Plasma aldosterone levels are elevated in patients with

47 Plasma aldosterone levels are elevated in patients with

48 Plasma aldosterone levels by radioimmunoassay demonstrat

49 The very high plasma aldosterone levels detected under hypovolemic or

50 ffects of an angiotensin receptor blocker on plasma aldosterone levels in patients with NYHA class II

51 Adrenalectomy + ALDO showed plasma aldosterone levels of 735 +/- 147 pg/ml; plasma p

52 In control mice, rosiglitazone did not alter plasma aldosterone levels or protein expression of ENaC

53 ical studies have demonstrated that elevated plasma aldosterone levels predict the development of ins

54 duced-potassium diet (rescue diet), although plasma aldosterone levels remained significantly increas

55 asurements of adrenal CYP11B2 expression and plasma aldosterone levels showed that increases in endog

56 was increased, and plasma renin activity and plasma aldosterone levels were decreased after the HS di

57 enin concentrations were modestly higher and plasma aldosterone levels were lower in Sglt2(-/-) mice.

58 At 2 wk, plasma renin activity and plasma aldosterone levels were lower in the POL group.

59 However, plasma aldosterone levels were significantly suppressed

60 Systolic BP (SBP), 24-h protein excretion, plasma aldosterone levels, 24-h urinary aldosterone excr

61 In Study 3, the relationship between plasma aldosterone levels, alcohol drinking and craving

62 1, we investigated the relationship between plasma aldosterone levels, ethanol self-administration a

63 hs accompanied with proportionate changes in plasma aldosterone levels, whereas plasma volumes ranged

64 hibited sodium loss through feces and higher plasma aldosterone levels.

65 on, increased GFR, and significantly reduced plasma aldosterone levels.

66 ese mice lost the normal circadian rhythm of plasma aldosterone levels.

67 d FE(Na) than wild-type mice despite similar plasma aldosterone levels.

68 phosphorylation of NCC protein, despite high plasma aldosterone levels.

69 ted thrombotic microangiopathy and decreased plasma aldosterone (<16 versus 710 +/- 91 pg/ml; P < 0.0

70 Plasma renin activity, plasma aldosterone, plasma and 24 h urine sodium and pot

71 Patients' work-up included plasma aldosterone, plasma renin activity, serum cortiso

72 negatively and significantly correlated with plasma aldosterone (r=-0.38, P=0.0006), 24-hour urinary

73 In conjunction with the lower plasma aldosterone, rats in the POL group had higher pla

74 ommon nonpressor effects included changes in plasma aldosterone, renal function, cardiac variables, a

75 ldosterone (r=-0.49, P<0.0001), and ratio of plasma aldosterone to plasma renin activity (r=-0.43, P<

76 ely evaluated with an early-morning ratio of plasma aldosterone to plasma renin activity and 24-hour

77 A plasma aldosterone to renin ratio is a useful screening

78 adenomas in patients with elevated ratios of plasma aldosterone to renin.

79 Plasma aldosterone was elevated approximately 5- and 15-

80 Plasma aldosterone was increased in slc26a3-null mice.

81 Plasma aldosterone was measured by radioimmunoassay in c

82 After 4 weeks of therapy, plasma aldosterone was reduced by valsartan 80 mg BID (-

83 Renal plasma flow and plasma aldosterone were measured before and after a 45-m

84 Of note, smaller increases in plasma aldosterone were required to adapt renal Na+ excr

85 in signaling elevated CYP11B2 expression and plasma aldosterone, whereas deficiency in leptin or lept