ライフサイエンスコーパス: plasma fibrinogen

1 e from retraction with normal recombinant or plasma fibrinogen.

2 opportunity to establish the source of human plasma fibrinogen.

3 s in the presence of a high concentration of plasma fibrinogen.

4 ly responsible for the depressed levels of a plasma fibrinogen.

5 protein cholesterol, C-reactive protein, and plasma fibrinogen.

6 -sensitivity C-reactive protein (hsCRP), and plasma fibrinogen.

7 remained the same over a wide range of total plasma fibrinogen.

8 ell-mediated retraction of clots formed from plasma fibrinogen.

9 fibrinogen can serve as a accurate model for plasma fibrinogen.

10 -8% to 10%, and a slightly greater range for plasma fibrinogen, -16% to 10%.

11 ; (2) binds to PECAM-1; (3) does not consume plasma fibrinogen; (4) accumulates in mouse lungs after

12 apolipoprotein B (1.03, 1.06, and 1.08 g/L), plasma fibrinogen (8.43, 8.44, and 9.53 micromol/L), hom

13 We therefore characterized plasma fibrinogen Aalpha-chain allotypes by electrospray

14 Tissue fibrin deposition and reduction of plasma fibrinogen accompanied this phenotype.

15 We measured baseline plasma fibrinogen among 199 incident cases of MI and 199

16 of a kindred with renal amyloidosis and low plasma fibrinogen and also the first report of amyloidos

17 effort that led to a successful outcome for plasma fibrinogen and discusses implications for future

18 Plasmin degrades plasma fibrinogen and factor VIII in a dose-dependent ma

19 We have investigated associations between plasma fibrinogen and factors operating in childhood and

20 A decrease in plasma fibrinogen and increases in thrombin-antithrombin

21 To examine whether plasma fibrinogen and PAI-1 antigen levels differ among

22 the vessel wall may therefore interact with plasma fibrinogen and promote platelet adhesion, leading

23 In all other analyses, we found that plasma fibrinogen and recombinant fibrinogen were remark

24 period of 13 d, and a tendency toward higher plasma fibrinogen and serum IL-6 levels.

25 polymerase chain reaction, and serology, and plasma fibrinogen and serum interleukin-6 (IL-6) were de

26 s the ligand binding site, which can bind to plasma fibrinogen and to a number of Arg-Gly-Asp (RGD)-t

27 anied by thrombin generation, consumption of plasma fibrinogen, and deposition of hepatic fibrin.

28 indexes of blood rheology (plasma viscosity, plasma fibrinogen, and hematocrit) in 106 patients with

29 ndialdehyde and 8-hydroxy-2'-deoxyguanosine, plasma fibrinogen, and white blood cells).

30 The authors have reported previously that plasma fibrinogen appears to rise after menopause and to

31 ted with FALP and approximately 17% of total plasma fibrinogen are bound to FALP.

32 This led to the FDA qualification of plasma fibrinogen as a prognostic or enrichment biomarke

33 als were also found to have higher levels of plasma fibrinogen at the time of surgery, with unchanged

34 ant recombinant fibrinogens were compared to plasma fibrinogens by following the time course of throm

35 f hyperfibrinogenemia, we show that elevated plasma fibrinogen concentration (1) elicits augmented fi

36 5 %, p= 0.038), with a parallel reduction of plasma fibrinogen concentration (mean (+/-SD), 157(+/-19

37 Small changes in plasma fibrinogen concentration are often clinically imp

38 complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a

39 cation) were inversely associated with adult plasma fibrinogen concentration in both sexes.

40 High plasma fibrinogen concentration is associated with an in

41 Estimates of the heritability of plasma fibrinogen concentration, an established predicto

42 o ICR mice did not significantly deplete the plasma fibrinogen concentration, co-administration of Dr

43 cidate the mechanism responsible for the low plasma fibrinogen concentration, simultaneous metabolic

44 er the 41 loci explain 3% of the variance in plasma fibrinogen concentration.

45 Normal plasma fibrinogen concentrations are critical to haemost

46 ymptoms of amyloidosis as yet but have lower plasma fibrinogen concentrations when compared with thei

47 blood platelet aggregation was enhanced, and plasma fibrinogen content, clot weight, and clot strengt

48 ise, neither decreased RBC ATP nor increased plasma fibrinogen explained the T/HS-induced changes tha

49 ping plaques, and the identification of high plasma fibrinogen (Fib) levels as an independent risk fa

50 the retraction was dependent on secretion of plasma fibrinogen from platelet alpha-granules.

51 Elevated plasma fibrinogen (> or =375 mg/dl) in the presence of d

52 Plasma fibrinogen has emerged as a risk factor for cardi

53 s of fibrinogen matrices prepared from human plasma fibrinogen (hFg), recombinant normal (rFg), and f

54 The results showed that human plasma fibrinogen (HPF) can be readily displaced from th

55 idemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of car

56 ism-related genes, have been associated with plasma fibrinogen in European Americans (EAs).

57 pes, and although the liver is the source of plasma fibrinogen in vivo in rats, this is not known in

58 plete clot lysis and complete destruction of plasma fibrinogen; in contrast, rSKDelta59 produced tota

59 Elevated plasma fibrinogen increases and low dose aspirin decreas

60 Plasma fibrinogen is a mixture of multiple molecular for

61 that a previously identified calcium site in plasma fibrinogen is absent when Gly-His-Arg-Pro-amide i

62 It is unclear whether elevated plasma fibrinogen is associated with both deep venous th

63 We tested the hypotheses that elevated plasma fibrinogen is associated with increased risk of D

64 These findings indicate that plasma fibrinogen is inversely associated with physical

65 vealed lower PI in patients with an elevated plasma fibrinogen level (> or =375 mg/dl), diabetes mell

66 ess level remained inversely associated with plasma fibrinogen level (beta = -1.3, 95% confidence int

67 Resting heart rate was also correlated with plasma fibrinogen level (r = 0.18, p<0.05).

68 the association between physical fitness and plasma fibrinogen level in 193 children 4-25 years old;

69 vely little is known about the correlates of plasma fibrinogen level in childhood.

70 An elevated plasma fibrinogen level is a risk factor for thrombotic

71 ogen concentrate infusion dosed to achieve a plasma fibrinogen level of 2.5 g/L in high-risk cardiac

72 (n = 60), targeted to achieve a postinfusion plasma fibrinogen level of 2.5 g/L.

73 least 1.61 micromol/L (> or =45.3 mg/dL), a plasma fibrinogen level of at least 10.35 micromol/L, a

74 o fib(+/-) littermate controls, which have a plasma fibrinogen level that is 70% of that of wild-type

75 sed plasma markers of coagulation, decreased plasma fibrinogen level, and widespread tissue fibrin de

76 al profile, including normal platelet count, plasma fibrinogen level, clotting time and fibrin crossl

77 did not show any major differences including plasma fibrinogen level, prothrombin time, and activated

78 t/obese and 19 lean individuals with MRI and plasma fibrinogen levels (marker of inflammation).

79 Our findings indicate that Cv-PC increases plasma fibrinogen levels and may provide a promising the

80 In 1997-1999, plasma fibrinogen levels and prevalences of the fibrinog

81 Elevated plasma fibrinogen levels are a major risk factor for thr

82 Elevated plasma fibrinogen levels are associated with increased r

83 Higher plasma fibrinogen levels are associated with increased r

84 ultiple linear regression analyses adjusting plasma fibrinogen levels for age, sex, race/ethnicity, t

85 f early onset of ischemic heart disease with plasma fibrinogen levels in children.

86 We raised plasma fibrinogen levels in mice via intravenous infusio

87 Plasma fibrinogen levels in the children were not relate

88 Plasma fibrinogen levels may be used to identify patient

89 platelet aggregability, we hypothesized that plasma fibrinogen levels may interact with Pl(A) genotyp

90 Plasma fibrinogen levels showed a graded inverse relatio

91 nts exhibit genotypes associated with higher plasma fibrinogen levels than healthy individuals.

92 The ancrod regimen was designed to decrease plasma fibrinogen levels to 1.18 to 2.03 micromol/L.

93 r the measurement of serum hsCRP levels, and plasma fibrinogen levels were determined using an automa

94 Graded relations of children's plasma fibrinogen levels were found with tertiles of bod

95 Plasma fibrinogen levels were lower in Blacks than in Wh

96 uce fibrinogen production, thereby elevating plasma fibrinogen levels.

97 and their correlations with serum hsCRP and plasma fibrinogen levels.

98 e (ESR), zeta sedimentation ratio (ZSR), and plasma fibrinogen levels.

99 re associated with a 7% lifelong increase in plasma fibrinogen levels; however, these genetic variant

100 Plasma fibrinogen measured either as thrombin-clottable

101 While the existence of gamma chains in plasma fibrinogen molecules has been known for many year

102 mer position of disulfide bond reduced human plasma fibrinogen prepared from fresh single donor or ou

103 generated from several purified fractions of plasma fibrinogen, purified proteolytic fragments of pla

104 ation after multivariable adjustment between plasma fibrinogen quintiles and risk of DVT alone (P-tre

105 Increasing plasma fibrinogen quintiles were associated with increas

106 admill testing was inversely associated with plasma fibrinogen (r = -0.24, p<0.001).

107 ibrinogen, purified proteolytic fragments of plasma fibrinogen, recombinant normal fibrinogen, and re

108 ntal stress testing in the laboratory, where plasma fibrinogen stress responses were smaller in happi

109 ssociations, together accounting for 3.7% of plasma fibrinogen variation.

110 brinogen can serve as a functional model for plasma fibrinogen, we have examined the conversion of fi

111 ents of RBC adenosine triphosphate (ATP) and plasma fibrinogen were performed.

112 Human and bovine plasma fibrinogens were also assayed for their ability t

113 Three studies showed increased plasma fibrinogen when dietary STA exceeded 9% of energy

114 We examined the association of baseline plasma fibrinogen with future risk of myocardial infarct

115 The interaction of human plasma fibrinogen with leukocyte integrins alpha(M)beta(