ライフサイエンスコーパス: plasma membrane

1 ease of the proteins from the vesicle to the plasma membrane.

2 rrival of the early and late proteins at the plasma membrane.

3 cific domains or morphologic features on the plasma membrane.

4 ode, in which SGs individually fuse with the plasma membrane.

5 ane, whereas ectosomes bud directly from the plasma membrane.

6 r newly formed vesicles originating from the plasma membrane.

7 rafficking of KATP and Kv2.1 channels to the plasma membrane.

8 o and localizes as puncta in cells along the plasma membrane.

9 dependent accumulation of the protein at the plasma membrane.

10 nes of lipid trafficking vesicles and in the plasma membrane.

11 as by directly binding prenylated Ras at the plasma membrane.

12 the FAF1-VCP complex and reduces FAF1 at the plasma membrane.

13 achinery, impairing its direct action on the plasma membrane.

14 by a redistribution of CHTs to the synaptic plasma membrane.

15 n reduces secretory granule targeting to the plasma membrane.

16 nrichment of the long TMEM260 isoform to the plasma membrane.

17 PIN-FORMED auxin efflux carriers within the plasma membrane.

18 ated vesicles prior to re-insertion into the plasma membrane.

19 events may be physically constrained by the plasma membrane.

20 ein-coupled receptors, which localize to the plasma membrane.

21 influx to replenish Ca(2+) losses across the plasma membrane.

22 cortex attached to the inner leaflet of the plasma membrane.

23 mately fusion of secretory vesicles with the plasma membrane.

24 eneath somatic, but not axonal or dendritic, plasma membrane.

25 ulum, and the Ca(2+) ion channel Orai in the plasma membrane.

26 ty to drive protein translocation across the plasma membrane.

27 MYO6 motor function at endosomes and at the plasma membrane.

28 tion of glucose transporter 4 (GLUT4) to the plasma membrane.

29 n of a synaptic vesicle with the presynaptic plasma membrane.

30 he localization of the UGT80B1 enzyme in the plasma membrane.

31 AMPA receptors and their trafficking to the plasma membrane.

32 ces stable proteins that are targeted to the plasma membrane.

33 somes, while aminolipid-SPIONs reside at the plasma membrane.

34 motes the maturation of ABCC6 mutants to the plasma membrane.

35 intracellular transport of receptors to the plasma membrane.

36 r), which tethers mitochondria to the ER and plasma membrane.

37 cle cells and is abundantly localized on the plasma membrane.

38 pathway, as well as copper export across the plasma membrane.

39 cts by stabilizing nutrient permeases at the plasma membrane.

40 lation-mediated trafficking of Nav1.5 to the plasma membrane.

41 te (PI(4,5)P2), the main lipid marker of the plasma membrane.

42 n (MLKL), which results in disruption of the plasma membrane.

43 f G protein-coupled receptors (GPCRs) at the plasma membrane.

44 s from the outer to the inner leaflet of the plasma membrane.

45 (3,4,5)-triphosphate (PIP3) within the spine plasma membrane.

46 erstanding of signal transduction across the plasma membrane.

47 om the nucleus and assembled en route to the plasma membrane.

48 nd that the OsALMT4 protein localizes to the plasma membrane.

49 nalized GPR15 receptors were recycled to the plasma membrane.

50 also promoted translocation of NDPK-C to the plasma membrane.

51 rnal stress of a rapidly growing wall to the plasma membrane.

52 on of alphaENaC immunoreactivity towards the plasma membrane.

53 s ligands occurs in a specific region of the plasma membrane.

54 rmeability effects on both intracellular and plasma membranes.

55 t rearrangement of cytoskeletal proteins and plasma membranes.

56 sed intact pro-EGF precursor on granular and plasma membranes.

57 tact and self-fusion of the apical and basal plasma membranes.

58 todynamic therapy (PDT), we designed a smart plasma membrane-activatable polymeric nanodrug by conjug

59 oxazolepropionic acid receptor levels at the plasma membrane, although their presence at distal dendr

60 ed a relocalization of beta-catenin from the plasma membrane and a loss of epithelial phenotype in CR

61 t cystic fibrosis channel (F508-CFTR) at the plasma membrane and after reconstitution into phospholip

62 specialised extension of the oligodendrocyte plasma membrane and clemastine fumarate can stimulate di

63 which cells divide, Piezo1 localizes to the plasma membrane and cytoplasm, whereas in dense regions

64 he sigma1R interacts with DAT at or near the plasma membrane and decreases methamphetamine-induced Ca

65 reveals that Rab8a is first recruited to the plasma membrane and dorsal ruffles, but it is retained d

66 ants to analyze their contributions to H-Ras plasma membrane and endomembrane distribution.

67 OAT2)), while in those treated with saponin (plasma membrane and ER membrane permeabilized), BeauIII

68 of nonvesicular sterol transport between the plasma membrane and ERC.

69 strict the lateral mobility of AtHIR1 at the plasma membrane and facilitate its oligomerization.

70 data reveal 2D dynamics of the mitochondria, plasma membrane and filopodia, and the 2D and 3D dynamic

71 the absence of RhoA, RhoB relocalized to the plasma membrane and functionally replaced RhoA with resp

72 or and Ca(2+) sensor for both heterotypic SG-plasma membrane and homotypic SG-SG fusion.

73 CR membrane localization and dynamics at the plasma membrane and in endosomal compartments, (c) TCR s

74 aturation but co-localizes with PD-L1 at the plasma membrane and in recycling endosomes, where it pre

75 reased localization of activated KRAS at the plasma membrane and induced tumour cell growth in vitro

76 rial species to interact with the eukaryotic plasma membrane and intracellular organelles.

77 yte, all three proteins were enriched in the plasma membrane and organelle membrane compartments.

78 x is a transmembrane machine that spans both plasma membrane and outer membrane and actively extrudes

79 structure and organization of the mammalian plasma membrane and review recent applications of super-

80 ch promotes the trafficking of Nav1.5 to the plasma membrane and stimulation of INa.

81 mechanical interplay between tension in the plasma membrane and stresses that develop within differe

82 oscillations: Hechtian adhesion between the plasma membrane and the cell wall of the growing tip act

83 The plasma membrane and the endocytic recycling compartment

84 ol, we examined sterol transport between the plasma membrane and the ERC using fluorescence recovery

85 which in turn induces DR5 clustering at the plasma membrane and thereby primes tumor cells to caspas

86 ctions between the voltage regulation of the plasma membrane and tonoplast in coordinating transport

87 Sphingolipids are a major component of plant plasma membranes and endomembranes, and mediate a divers

88 ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid compl

89 TF is much less efficiently localized to the plasma membrane, and it is not incorporated into the vir

90 res that ezrin is only phosphorylated at the plasma membrane, and with high specificity by the apical

91 xpected synergies appear, including with the plasma membrane anion channels and H(+)-ATPase and with

92 e found that the K-Ras anchor binds selected plasma membrane anionic lipids with defined head groups

93 ized to different regions of the pollen tube plasma membrane, apical vesicle-rich inverted cone regio

94 educed aquaporin-2 endocytosis and prolonged plasma membrane aquaporin-2 retention.

95 Eukaryotic plasma membranes are compartmentalized into functional l

96 more, the biophysical properties imparted to plasma membranes are regulated by fatty acid chain profi

97 bodies and their subsequent fusion with the plasma membrane, are also released from astrocytes via e

98 equiring a constant adaptation of the cell's plasma membrane area to prevent cell lysis.

99 their correct assembly and expression at the plasma membrane as a single functional complex, (b) TCR

100 e show that this protein is localized at the plasma membrane as well as in endosomes and soluble in t

101 mpaired anterograde vesicle transport to the plasma membrane as well as retrograde vesicle tethering

102 eir ability to shuttle between endosomes and plasma membranes, as well as on their lateral accumulati

103 Among them, the plasma membrane-associated Arabidopsis proteins OCTOPUS

104 olog of Indy (mIndy, Slc13a5) encoding for a plasma membrane-associated citrate transporter expressed

105 rylation drives the association of GRK2 with plasma membrane-associated DOR.

106 Self-assembly of plasma membrane-associated Ras GTPases has major implica

107 The plasma membrane-associated tyrosine phosphatase PTPRO is

108 te the fusion of secretory vesicles with the plasma membrane at sites of polarized growth, and acts a

109 We find hot spots on the plasma membrane, at least partially defined by the cytos

110 DNA to living cells requires overcoming the plasma membrane barrier without harming the cell during

111 omer SGs that undergoes no residence time on plasma membrane before fusion and, to a lesser extent, a

112 in, which link the actin cytoskeleton to the plasma membrane, bind membranes with very high affinity

113 Using this approach, we discovered that plasma membrane-bound respiratory syncytial virus G rapi

114 Thus, GPCRs function not only at the plasma membrane but also in endosomes to control complex

115 lacks the CNB-A domain, was recruited to the plasma membrane but did not accumulate at granules.

116 g, is not evenly distributed over the entire plasma membrane but instead is highly enriched on microv

117 activation, the protein redistributes to the plasma membrane, but the underlying molecular mechanisms

118 have been developed to overcome the cellular plasma membrane, but they all result in reduced cell via

119 or cells requires evagination of its ciliary plasma membrane by an unknown molecular mechanism.

120 the trapping of newly formed virions at the plasma membrane by BST2, we found that it does not inhib

121 lar RNA processing they must first cross the plasma membrane by endocytosis.

122 pling may extend to the outer leaflet of the plasma membrane by examining the flow of GPI-anchored pr

123 Resultant Ca(2+) sparks activate plasma membrane Ca(2+) -activated K(+) (BKCa ) channels,

124 KEY POINTS: The role of plasma membrane Ca(2+) -ATPase 1 (PMCA1) in Ca(2+) homeo

125 ABSTRACT: To determine the role of plasma membrane Ca(2+) -ATPase 1 (PMCA1) in maintaining

126 the regulative N terminus of the Arabidopsis plasma membrane Ca(2+)-ATPase isoform 8 (ACA8) and that

127 Plasma membrane calcium ATPase 2 (PMCA2) is a calcium pu

128 In response to flow, the plasma membrane calcium channel ORAI1 mediates calcium i

129 -gated L-type Ca(2+) channels (LTCCs) in the plasma membrane can initiate a signaling pathway that ul

130 Sub-cellular investigations reveal that the plasma membrane cell fate regulator, SCRAMBLED (SCM), is

131 n occur in response to Ca(2+) influx through plasma membrane channels and Ca(2+) release from intrace

132 lasmic reticulum, although Ca(2+) influx via plasma membrane channels is also necessary to sustain th

133 Decreased VAC14 expression increased plasma membrane cholesterol, facilitating Salmonella doc

134 LRX proteins might play a role in cell wall-plasma membrane communication, influencing cell wall for

135 pin, among other phospholipids in the apical plasma membrane compared to the basolateral plasma membr

136 to examine the organization and dynamics of plasma membrane components, providing insight into the f

137 and a clustering of Munc13-4 at sites of WPB-plasma membrane contact.

138 ted pit, in equilibrium with the surrounding plasma membrane, contains phosphatidylinositol-4,5-bipho

139 owever, the reciprocal regulation of how the plasma membrane curvature affects the activities of endo

140 hown that CME proteins actively modulate the plasma membrane curvature.

141 PS asymmetry on the plasma membrane depends on the activities of P4-ATPases,

142 Changes in plasma membrane depolarization and elevated intracellula

143 2+) homeostasis in excitable cells following plasma membrane depolarization.

144 ein 90, were identified in samples of apical plasma membrane-derived exosomes, but not in basolateral

145 To examine whether the structure of the axon plasma membrane determines its overall stiffness, we int

146 rotein entered the cytosol by traversing the plasma membrane directly, like a small-molecule prodrug.

147 ne and its fluorescent analog JHC1-64 on the plasma membrane distribution of wild-type DAT and two no

148 How cells specify morphologically distinct plasma membrane domains is poorly understood.

149 Caveolae are protein-dense plasma membrane domains structurally composed of caveoli

150 triggers insertion of GLUT4 into the axonal plasma membrane driven by activation of the metabolic se

151 pIX NPs can disassemble and stably attach to plasma membranes due to the membrane affinity of PpIX mo

152 tory granules, which are integrated into the plasma membrane during regulated exocytosis.

153 ase uPA and astrocytes recruit uPAR to their plasma membrane during the recovery phase from a hypoxic

154 retically describe the interplay between the plasma membrane dynamics and a physically connected cell

155 to decipher specific influences on molecular plasma membrane dynamics.

156 tly thought to involve PIN-FORMED (PIN)-type plasma membrane efflux carriers that generate subcellula

157 are commonly considered as hallmarks of the plasma membrane, endosomes, and lysosomes, these compart

158 At the plasma membrane, ERK1/2-mediated phosphorylation and 14-

159 ane-derived exosomes, but not in basolateral plasma membrane exosomes from mouse cortical collecting

160 plasma membrane compared to the basolateral plasma membrane exosomes.

161 ates RA-FLS adhesion through controlling the plasma membrane expression and activation of beta1 integ

162 n, which upon CRISPR knockout led to reduced plasma membrane flow directionality despite increased ac

163 ensing is not dependent on its function as a plasma membrane folate transporter.

164 Akt is translocated to the plasma membrane for activation.

165 lated TF is preferentially trafficked to the plasma membrane for virus budding.

166 ntain energy homeostasis as well as to build plasma membranes for newly synthesized cells.

167 ntrol of physical properties of their apical plasma membranes for normal development and function.

168 the secretion of AUX1 influx carrier to the plasma membrane from the TGN during hook development and

169 Rafts are involved in most plasma membrane functions by selective recruitment and r

170 fy the expression of either the total or the plasma membrane GABAARs or gephyrin.

171 administration rapidly increased (p < 0.05) plasma membrane GLUT4 content in both red and white gast

172 heory proposed in the 1970s, auxin activates plasma membrane H(+)-ATPases (PM H(+)-ATPases) to facili

173 een cholesterol and sphingolipids within the plasma membrane has long been implicated in endocytic me

174 HA and M2 are strongly coclustered in the plasma membrane; however, in the case of NA and M2, clus

175 ate that cytosolic Rasa3 translocates to the plasma membrane in a PI3K-dependent manner upon activati

176 g and translocation of RodZ to the bacterial plasma membrane in an obligatorily cotranslational mecha

177 activity triggers lysosomal fusion with the plasma membrane in dendrites.

178 pt mature erythrocytes, but do not reach the plasma membrane in erythroblasts and are degraded by the

179 aps newly assembled enveloped virions at the plasma membrane in infected cells, and it induces NF-kap

180 lioside receptor in the outer leaflet of the plasma membrane in intestinal (HT-29) cells and thereby

181 oring protein 79/150 (AKAP), residing at the plasma membrane in neurons, scaffolds PKA to target prot

182 ction-mediated translocation of GLUT4 to the plasma membrane in skeletal muscle.

183 n the cortical longitudinal actin cables and plasma membrane in the shank region of growing pollen tu

184 itol polyphosphate 5-phosphatase (Inp54p) to plasma membranes in the presence of rapamycin.

185 ed that alpha1D protein was localized at the plasma membrane, in cytosol and cell nuclei.

186 of the EGFR-Grb2 binding interaction in the plasma membrane, in the presence and absence of activati

187 oteins expressed at the inner leaflet of the plasma membrane, including alpha-actinin-1, moesin, 14-3

188 s two orders of magnitude slower than in the plasma membrane, indicating that HIV-1 envelope is intri

189 ression of KCNQ1 trapped beta-catenin at the plasma membrane, induced a patent lumen in CRC spheroids

190 ll death, ESCRT-III controls the duration of plasma membrane integrity.

191 n balance was shown to induce narrow tubular plasma membrane invaginations enriched with sphingosine

192 ranes, induces the formation of cristae-like plasma membrane invaginations.

193 s showed that one pool of cholesterol in the plasma membrane is "accessible" to binding by a modified

194 Although tension in the plasma membrane is generally considered to be an importa

195 Plasma Membrane is the primary structure for adjusting t

196 ia virus protein F11, which localizes to the plasma membrane, is required for ROCK-mediated cell cont

197 nslocate the virus from the cytoplasm to the plasma membrane leading to virion budding.

198 These results suggest that plasma membrane localization is required for Ser5 antivi

199 ot palmitoylated display drastically reduced plasma membrane localization, which effectively prevents

200 The plasma membrane-localized SbSUT1 and SbSUT5 exhibited a

201 this phenomenon, here we confirmed that the plasma membrane-localized transporter (renamed CDR6/ROA1

202 y discharge during invasion and to host cell plasma membrane lysis during egress.

203 Surface charges at the inner leaflet of the plasma membrane may contribute to regulate the surface r

204 how the asymmetric lipid distribution of the plasma membrane might facilitate fusion pore formation d

205 eference nor variant APOL1s localized on the plasma membrane, Na(+) and K(+) gradients were maintaine

206 n ENT members hENT1 and hENT2, which mediate plasma membrane nucleoside transport at pH 7.4, hENT3 is

207 Methionine transport across plasma membranes occurs via the large amino acid transpo

208 Partition and transportation of drug in the plasma membrane of a mammalian cell are the prerequisite

209 istry to visualize their distribution on the plasma membrane of different cells with virtually molecu

210 rotein located and functioning at the apical plasma membrane of epithelial cells, is required for epi

211 In the plasma membrane of eukaryotic cells, proteins and lipids

212 -labeled Na(+),K(+)-ATPase constructs in the plasma membrane of HEK293T cells by fluorescence correla

213 onverts ATP to electrochemical energy at the plasma membrane of higher plants.

214 physical and biochemical function within the plasma membrane of living cells.

215 The plasma membrane of mammalian cells undergoes constitutiv

216 Primary cilia are hairlike extensions of the plasma membrane of most mammalian cells that serve speci

217 hosphate kinases (NDPKs) are enriched at the plasma membrane of patients with end-stage HF, but the f

218 edominant potassium channel expressed at the plasma membrane of rheumatoid arthritis fibroblast-like

219 It rapidly permeabilizes the plasma membrane of the ascomycete fungi Fusarium gramine

220 in the fusion of secretory vesicles with the plasma membrane of the growing bud.

221 olve minute PKA activity microdomains on the plasma membranes of living cells and to uncover the role

222 terol-binding proteins bind uniformly to the plasma membrane or bind preferentially to specific domai

223 ted in which Hog1 was either tethered to the plasma membrane or constitutively nuclear.

224 s binding partner CIBN to bind either to the plasma membrane or to the mitochondrial membrane.

225 Eukaryotic plasma membrane organization theory has long been contro

226 oteins require preferential affinity for the plasma membrane over thylakoids to correctly position th

227 ) acting across two nanodomains, one between plasma membrane P/Q Ca(2+) channels and endoplasmic reti

228 racellular Ca(2+) subsequent to LLO-mediated plasma membrane perforation is required for the activati

229 ells prepared by a treatment with digitonin (plasma membrane permeabilized), BeauIII selectively inhi

230 d phospholipase Cgamma, enzymes that deplete plasma membrane phosphatidylinositol 4,5-bisphosphate (P

231 al organization of molecules in the cellular plasma membrane plays an important role in cellular sign

232 Internalization of proteins from the plasma membrane (PM) allows for cell-surface composition

233 of the invading cell as well as nonapoptotic plasma membrane (PM) blebbing in this cellular motile pr

234 protein whose reversible localization to ER-plasma membrane (PM) contacts is governed by phosphoryla

235 In this study, we investigate the impact of plasma membrane (PM) integrity on bacterial replication

236 lasmic reticulum (ER) proteins that bind the plasma membrane (PM) via C2 domains and transport lipids

237 l function at the cytoplasmic surface of the plasma membrane (PM), where they are activated by cell s

238 stream signalling components, which exist in plasma membrane (PM)-localised protein complexes.

239 ed transport mechanisms to ensure that their plasma membranes (PMs) are optimally supplied with chole

240 elrhodopsins are widely used to modulate the plasma membrane potential of excitable cells, mitochondr

241 ne (PS) exposure on the outer leaflet of the plasma membrane preceded loss of PM integrity.

242 exes is critical for main-tenance of optimal plasma membrane protein composition.

243 ation study indicated that it is an integral plasma membrane protein.

244 ate that the US12 family selectively targets plasma membrane proteins and plays key roles in regulati

245 Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in polarized grow

246 undances of receptor-associated and resident plasma membrane proteins that were not readily observed

247 About a third of ARMMs-enriched proteins are plasma membrane proteins, including the NOTCH2 receptor.

248 o predominantly tubular carriers shared with plasma membrane proteins, independently of signal-adapto

249 While the plasma membrane proteome remained largely invariable, we

250 quantitative approach to profile the entire plasma membrane proteome, we find that CMTM6 displays sp

251 gether, whereas unattached cells make active plasma membrane protrusions to migrate.

252 ystin-1 (PC1) and polycystin-2 (PC2), form a plasma membrane receptor-ion channel complex.

253 lack of APP leads to a dramatic increase in plasma membrane recruitment of endogenous arrestin 3 fol

254 found to control the balance between GLP-1R plasma membrane recycling and lysosomal degradation and,

255 s cytoplasmic Cl(-) homeostasis and promotes plasma membrane remodeling required for mammalian epithe

256 ved in tethering of exocytic vesicles to the plasma membrane, rescued secretion and bud growth defect

257 Ltc1 and Ltc3/4 function at the vacuole and plasma membrane, respectively, to create membrane domain

258 e triggered the fusion of lysosomes with the plasma membrane, resulting in the release of Cathepsin B

259 Upon crossing the plasma membrane, signal peptides are cleaved off and mat

260 hat is important for the organization of the plasma membrane, signal transduction, and membrane traff

261 his possibility, we modeled exocytosis using plasma membrane SNARE-containing planar-supported bilaye

262 interestingly, with the outer leaflet of the plasma membrane, suggesting a role at the host-parasite

263 Instead, Sec22b in combination with plasma membrane syntaxin 3 and syntaxin 4 as well as SNA

264 E) onto a binary SNARE complex on the target plasma membrane (t-SNARE).

265 ocesses associated with changes in effective plasma membrane tension induce significant spatiotempora

266 We found that DRG neurons had a plasma membrane tension of approximately 54 pN/mum, and

267 le into small invaginating structures at the plasma membrane termed clathrin-coated pits (CCPs) that

268 Unlike TLRs located on the plasma membrane that dimerize on the membrane after liga

269 areas promote structural changes within the plasma membrane that segregate membrane receptors and af

270 e are abundant flask-shaped invaginations of plasma membranes that buffer membrane tension through th

271 es the overall ceramide concentration in the plasma membrane, the quantity of CRPs, and their size.

272 Interestingly, when encountering plasma membranes, the GC-PEG-PpIX NPs can disassemble an

273 racellular vesicles that bud directly at the plasma membrane; their function is poorly understood.

274 igration when localized appropriately to the plasma membrane, thereby having an essential role in can

275 demonstrated that myomaker functions at the plasma membrane to drive fusion.

276 undergo rapid tetrazine ligation within the plasma membrane to generate the HIDE probe DiI-SiR.

277 a necrotic DFNA5-N fragment that targets the plasma membrane to induce secondary necrosis/pyroptosis.

278 TLR4, dimerize and move laterally across the plasma membrane to phosphatidylinositol (4,5)-bisphospha

279 embrane lipids, are normally returned to the plasma membrane to sustain this action.

280 tin binding protein ezrin relocated from the plasma membrane to the cytosol as early as 2 h after rad

281 recruitment to endosome membranes and GLUT1 plasma membrane translocation.

282 sor CueR controls cytoplasmic chaperones and plasma membrane transporters, whereas CopR/S responds to

283 totoxic to cells is developed to disrupt the plasma membrane under gentle ultrasound insonation, 1MHz

284 cessary for efficient Dvl recruitment to the plasma membrane upon Wnt stimulation of Fzd receptor and

285 Here we report experiments utilizing giant plasma membrane vesicles (GPMVs) to explore how membrane

286 Further evidence from giant plasma membrane vesicles suggests that the presence of a

287 different efficiencies into Golgi complex to plasma membrane vesicular carriers, and 2) the different

288 otein which is usually found anchored to the plasma membrane via a glycophosphatidylinositol (GPI) an

289 mains of these CARMIL isoforms interact with plasma membranes, vimentin intermediate filaments, SH3-c

290 PIN1 phosphorylation at the basal and apical plasma membrane was differentially sensitive to BFA trea

291 MC4R and clathrin were redistributed to the plasma membrane where they colocalized to sites that app

292 usters also function to anchor dynein to the plasma membrane, where dynein captures and walks along a

293 6 shifts localization of this complex to the plasma membrane, where it associates with the tight-junc

294 essed in yeast, human Eps15 localized to the plasma membrane, where it recruited late-phase CME prote

295 osomes and released when these fuse with the plasma membrane, whereas ectosomes bud directly from the

296 were normally processed and targeted to the plasma membrane, whereas their PC secretion activity was

297 in part by depolarization of senescent cell plasma membrane, which leads to primary cilia defects an

298 membrane protein interactions in the intact plasma membrane, while accounting for cell heterogeneity

299 DNER is present on the plasma membrane, while NFIA is confined to the nucleus,

300 itutive internalization and recycling to the plasma membrane with agonist binding inducing receptor r