ライフサイエンスコーパス: plasmatocyte

1 ifically required for the differentiation of plasmatocytes.

2 d Ush in dpp mutants leads to hyperplasia of plasmatocytes.

3 ivates a class of insect immune cells called plasmatocytes.

4 causes crystal cells to be transformed into plasmatocytes.

5 ivates a class of insect immune cells called plasmatocytes.

6 ytes involved in insect cellular immunity is plasmatocytes.

7 tide and that other peptidyl factors mediate plasmatocyte adhesion responses.

8 is that Ush participates in a switch between plasmatocyte and lamellocyte fate in a common precursor

9 asmatocyte production, but Dif controls both plasmatocyte and lamellocyte production.

10 phila melanogaster, the lymph gland produces plasmatocytes and crystal cells that are not released un

11 major types of D. melanogaster blood cells, plasmatocytes and crystal cells.

12 and induces myeloproliferative expansion of plasmatocytes and crystal cells.

13 Here, we use insect plasmatocytes and hemocyte-like Drosophila S2 cells to c

14 Plasmatocytes are reduced in number, but still express t

15 , the peripodial epithelium and blood cells (plasmatocytes) associated with the developing retina.

16 We further found that the plasmatocyte calcium burst is suppressed by G1 venom in

17 Finally, by genetically manipulating plasmatocyte calcium levels, we were able to alter fly i

18 Mature plasmatocytes can proliferate but it is not known if cry

19 kin in Drosophila larvae, blood cells called plasmatocytes can transform into other classes of blood

20 cells, whereas mature haemocytes comprising plasmatocytes, crystal cells and lamellocytes are periph

21 tages three types of hemocytes are produced, plasmatocytes, crystal cells, and lamellocytes, and thei

22 es of terminally differentiated blood cells: plasmatocytes, crystal cells, and lamellocytes.

23 itoid wasp venom proteins led us to identify plasmatocyte cytoplasmic calcium bursts as an important

24 clarify the role of these redundant genes in plasmatocyte development.

25 has previously been shown to be required for plasmatocyte development.

26 Plasmatocytes differentiate into adhesive lamellocytes t

27 present a transitory state in prohemocyte to plasmatocyte differentiation.

28 at positively and cell-autonomously controls plasmatocyte differentiation.

29 udens larvae caused a transient depletion of plasmatocytes from circulation.

30 ic peptide at concentrations >/=2 nM induced plasmatocytes from P. includens to spread on the surface

31 ytes lacking Stat fail to differentiate into plasmatocytes, indicating that Stat positively and cell-

32 The major blood cell type, called plasmatocyte, is small, non-adhesive and phagocytic.

33 gland gives rise to three mature cell types: plasmatocytes, lamellocytes, and crystal cells.

34 st closely resemble mammalian myeloid cells: plasmatocytes (macrophage-like cells), crystal cells (in

35 hages, gcm cannot be the sole determinant of plasmatocyte/macrophage differentiation.

36 gcm has a role in the differentiation of the plasmatocyte/macrophage lineage of hemocytes.

37 hes of Drosophila hematopoiesis give rise to plasmatocytes/macrophages and crystal cells.

38 the Drosophila hematopoietic repertoire are plasmatocytes/macrophages and crystal cells.

39 of prohemocytes in the cortical zone induces plasmatocyte maturation in adjacent hemocytes.

40 Further analysis revealed that Wee1 inhibits plasmatocyte maturation through upregulation of Tiggrin

41 ressed in the LG, is a specific regulator of plasmatocyte maturation.

42 ingly, we found that fly immune cells termed plasmatocytes normally undergo a cytoplasmic calcium bur

43 ce mutation of gcm causes only a decrease in plasmatocyte numbers without changing their ability to c

44 like gcm, mutation of gcm2 leads to reduced plasmatocyte numbers.

45 other was active in hemocyte precursors and plasmatocytes only.

46 However, less is known about how the plasmatocyte pool of the LG is established and matures.

47 e required together for the proliferation of plasmatocyte precursors, the expression of Croquemort pr

48 dl primarily stimulates plasmatocyte production, but Dif controls both plasmatoc

49 -1 and -2 are essential for crystal cell and plasmatocyte production, respectively.

50 ired for the production of crystal cells and plasmatocytes, respectively.

51 uggests that only a certain subpopulation of plasmatocytes responds to the peptide and that other pep

52 To identify residues important for plasmatocyte spreading activity, we bioassayed PSP mutan

53 tured domain of PSP and was found to have no plasmatocyte spreading activity.

54 Plasmatocyte spreading peptide (PSP) is a 23-amino acid

55 The structure of the recently identified plasmatocyte spreading peptide from the moth Pseudoplusi

56 d structured domains of PSP are required for plasmatocyte-spreading activity.

57 Plasmatocyte-spreading peptide (PSP) is a 23-amino acid

58 Plasmatocyte-spreading peptide (PSP) is a 23-amino acid

59 This peptide, designated plasmatocyte-spreading peptide (PSP1), contains 23 amino

60 which selectively affects mitochondria-rich plasmatocyte survival and function, leading to melanotic

61 s indicated that this peptide induced 75% of plasmatocytes that were double-labeled by the monoclonal

62 ons is accompanied by high concentrations of plasmatocytes, the major hemocyte class in uninfected co

63 With this approach, we discriminate and sort plasmatocytes, the major hemocyte subset, from lamellocy

64 th mRNAs are expressed in granular cells and plasmatocytes, the primary classes of hemocytes involved

65 Ush is expressed in hemocyte precursors and plasmatocytes throughout embryogenesis and larval develo

66 -dependent manner, leading to the failure of plasmatocytes to become activated and migrate toward G1

67 on of Croquemort protein, and the ability of plasmatocytes to convert into macrophages.

68 sia includens that mediates the spreading of plasmatocytes to foreign surfaces.

69 nduces a class of insect immune cells called plasmatocytes to spread on foreign surfaces.

70 d, whereas plasma induced significantly more plasmatocytes to spread.

71 iginate through a Notch-dependent process of plasmatocyte transdifferentiation.

72 rin mutants exhibit precocious maturation of plasmatocytes, whereas Tiggrin overexpression blocks thi

73 multiple lineages, including macrophage-like plasmatocytes, which comprise the vast majority of matur

74 pomorph larvae had a 35% decreased number of plasmatocytes with a 45% reduced active mitochondrial st